-
1
-
-
13944281226
-
Molecular functions of BRCA1 in the DNA damage response
-
Scully, R., Xie, A., and Nagaraju, G. (2004) Molecular functions of BRCA1 in the DNA damage response. Cancer Biol. Ther. 3, 521-527.
-
(2004)
Cancer Biol. Ther
, vol.3
, pp. 521-527
-
-
Scully, R.1
Xie, A.2
Nagaraju, G.3
-
2
-
-
0036220871
-
BRCA1-dependent and independent functions of BARD1
-
Irminger-Finger, I., and Leung, W. C. (2002) BRCA1-dependent and independent functions of BARD1. Int. J. Biochem. Cell Biol. 34, 582-587.
-
(2002)
Int. J. Biochem. Cell Biol
, vol.34
, pp. 582-587
-
-
Irminger-Finger, I.1
Leung, W.C.2
-
3
-
-
10544231876
-
Identification of a RING protein that can interact in vivo with the BRCA1 gene product
-
Wu, L. C., Wang, Z. W., Tsan, J. T., Spillman, M. A., Phung, A., Xu, X. L., Yang, M. C., Hwang, L. Y., Bowcock, A. M., and Baer, R. (1996) Identification of a RING protein that can interact in vivo with the BRCA1 gene product. Nat. Genet. 14, 430-440.
-
(1996)
Nat. Genet
, vol.14
, pp. 430-440
-
-
Wu, L.C.1
Wang, Z.W.2
Tsan, J.T.3
Spillman, M.A.4
Phung, A.5
Xu, X.L.6
Yang, M.C.7
Hwang, L.Y.8
Bowcock, A.M.9
Baer, R.10
-
4
-
-
0037610801
-
Binding and recognition in the assembly of an active BRCA1/BARD1 ubiquitin-ligase complex
-
Brzovic, P. S., Keeffe, J. R., Nishikawa, H., Miyamoto, K., Fox, D., III, Fukuda, M., Ohta, T., and Klevit, R. (2003) Binding and recognition in the assembly of an active BRCA1/BARD1 ubiquitin-ligase complex. Proc. Natl. Acad. Sci. U.S.A. 100, 5646-5651.
-
(2003)
Proc. Natl. Acad. Sci. U.S.A
, vol.100
, pp. 5646-5651
-
-
Brzovic, P.S.1
Keeffe, J.R.2
Nishikawa, H.3
Miyamoto, K.4
Fox III, D.5
Fukuda, M.6
Ohta, T.7
Klevit, R.8
-
5
-
-
0034804672
-
Structure of a BRCA1-BARD1 heterodimeric RING-RING complex
-
Brzovic, P. S., Rajagopal, P., Hoyt, D. W., King, M. C., and Klevit, R. E. (2001) Structure of a BRCA1-BARD1 heterodimeric RING-RING complex. Nat. Struct. Biol. 8, 833-837.
-
(2001)
Nat. Struct. Biol
, vol.8
, pp. 833-837
-
-
Brzovic, P.S.1
Rajagopal, P.2
Hoyt, D.W.3
King, M.C.4
Klevit, R.E.5
-
6
-
-
0031046294
-
A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins
-
Bork, P., Hofmann, K., Bucher, P., Neuwald, A. F., Altschul, S. F., and Koonin, E. V. (1997) A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins. FASEB J. 11, 68-76.
-
(1997)
FASEB J
, vol.11
, pp. 68-76
-
-
Bork, P.1
Hofmann, K.2
Bucher, P.3
Neuwald, A.F.4
Altschul, S.F.5
Koonin, E.V.6
-
7
-
-
0031031787
-
From BRCA1 to RAP1: A widespread BRCT module closely associated with DNA repair
-
Callebaut, I., and Mornon, J. P. (1997) From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair. FEBS Lett. 400, 25-30.
-
(1997)
FEBS Lett
, vol.400
, pp. 25-30
-
-
Callebaut, I.1
Mornon, J.P.2
-
8
-
-
6344287454
-
Interactions between BRCT repeats and phosphoproteins: Tangled up in two
-
Glover, J. N., Williams, R. S., and Lee, M. S. (2004) Interactions between BRCT repeats and phosphoproteins: tangled up in two. Trends Biochem. Sci. 29, 579-585.
-
(2004)
Trends Biochem. Sci
, vol.29
, pp. 579-585
-
-
Glover, J.N.1
Williams, R.S.2
Lee, M.S.3
-
9
-
-
20644461718
-
BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function
-
Cantor, S. B., Bell, D. W., Ganesan, S., Kass, E. M., Drapkin, R., Grossman, S., Wahrer, D. C., Sgroi, D. C., Lane, W. S., Haber, D. A., and Livingston, D. M. (2001) BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function. Cell 105, 149-160.
-
(2001)
Cell
, vol.105
, pp. 149-160
-
-
Cantor, S.B.1
Bell, D.W.2
Ganesan, S.3
Kass, E.M.4
Drapkin, R.5
Grossman, S.6
Wahrer, D.C.7
Sgroi, D.C.8
Lane, W.S.9
Haber, D.A.10
Livingston, D.M.11
-
10
-
-
0032566753
-
The C-terminal (BRCT) domains of BRCA1 interact in vivo with CtIP, a protein implicated in the CtBP pathway of transcriptional repression
-
Yu, X., Wu, L. C., Bowcock, A. M., Aronheim, A., and Baer, R. (1998) The C-terminal (BRCT) domains of BRCA1 interact in vivo with CtIP, a protein implicated in the CtBP pathway of transcriptional repression. J. Biol. Chem. 273, 25388-25392.
-
(1998)
J. Biol. Chem
, vol.273
, pp. 25388-25392
-
-
Yu, X.1
Wu, L.C.2
Bowcock, A.M.3
Aronheim, A.4
Baer, R.5
-
11
-
-
0033574543
-
Binding of CtIP to the BRCT repeats of BRCA1 involved in the transcription regulation of p21 is disrupted upon DNA damage
-
Li, S., Chen, P. L., Subramanian, T., Chinnadurai, G., Tomlinson, G., Osborne, C. K., Sharp, Z. D., and Lee, W. H. (1999) Binding of CtIP to the BRCT repeats of BRCA1 involved in the transcription regulation of p21 is disrupted upon DNA damage. J. Biol. Chem. 274, 11334-11338.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 11334-11338
-
-
Li, S.1
Chen, P.L.2
Subramanian, T.3
Chinnadurai, G.4
Tomlinson, G.5
Osborne, C.K.6
Sharp, Z.D.7
Lee, W.H.8
-
12
-
-
34547655427
-
CCDC98 is a BRCA1-BRCT domain-binding protein involved in the DNA damage response
-
Kim, H., Huang, J., and Chen, J. (2007) CCDC98 is a BRCA1-BRCT domain-binding protein involved in the DNA damage response. Nat. Struct. Mol. Biol. 14, 710-715.
-
(2007)
Nat. Struct. Mol. Biol
, vol.14
, pp. 710-715
-
-
Kim, H.1
Huang, J.2
Chen, J.3
-
13
-
-
34547662882
-
CCDC98 targets BRCA1 to DNA damage sites
-
Liu, Z., Wu, J., and Yu, X. (2007) CCDC98 targets BRCA1 to DNA damage sites. Nat. Struct. Mol. Biol. 14, 716-720.
-
(2007)
Nat. Struct. Mol. Biol
, vol.14
, pp. 716-720
-
-
Liu, Z.1
Wu, J.2
Yu, X.3
-
14
-
-
0142240342
-
BRCT repeats as phosphopeptide-binding modules involved in protein targeting
-
Manke, I. A., Lowery, D. M., Nguyen, A., and Yaffe, M. B. (2003) BRCT repeats as phosphopeptide-binding modules involved in protein targeting. Science 302, 636-639.
-
(2003)
Science
, vol.302
, pp. 636-639
-
-
Manke, I.A.1
Lowery, D.M.2
Nguyen, A.3
Yaffe, M.B.4
-
15
-
-
0142147272
-
The BRCT domain is a phospho-protein binding domain
-
Yu, X., Chini, C. C., He, M., Mer, G., and Chen, J. (2003) The BRCT domain is a phospho-protein binding domain. Science 302, 639-642.
-
(2003)
Science
, vol.302
, pp. 639-642
-
-
Yu, X.1
Chini, C.C.2
He, M.3
Mer, G.4
Chen, J.5
-
16
-
-
2542490186
-
Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1
-
Williams, R. S., Lee, M. S., Hau, D. D., and Glover, J. N. (2004) Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1. Nat. Struct. Mol. Biol. 11, 519-525.
-
(2004)
Nat. Struct. Mol. Biol
, vol.11
, pp. 519-525
-
-
Williams, R.S.1
Lee, M.S.2
Hau, D.D.3
Glover, J.N.4
-
17
-
-
2542489188
-
Structure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancer
-
Clapperton, J. A., Manke, I. A., Lowery, D. M., Ho, T., Haire, L. F., Yaffe, M. B., and Smerdon, S. J. (2004) Structure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancer. Nat. Struct. Mol. Biol. 11, 512-518.
-
(2004)
Nat. Struct. Mol. Biol
, vol.11
, pp. 512-518
-
-
Clapperton, J.A.1
Manke, I.A.2
Lowery, D.M.3
Ho, T.4
Haire, L.F.5
Yaffe, M.B.6
Smerdon, S.J.7
-
18
-
-
2342484423
-
Structure of the BRCT repeats of BRCA1 bound to a BACH1 phosphopeptide: Implications for signaling
-
Shiozaki, E. N., Gu, L., Yan, N., and Shi, Y. (2004) Structure of the BRCT repeats of BRCA1 bound to a BACH1 phosphopeptide: implications for signaling. Mol. Cell 14, 405-412.
-
(2004)
Mol. Cell
, vol.14
, pp. 405-412
-
-
Shiozaki, E.N.1
Gu, L.2
Yan, N.3
Shi, Y.4
-
19
-
-
23944510641
-
Structural basis for cell cycle checkpoint control by the BRCA1-CtIP complex
-
Varma, A. K., Brown, R. S., Birrane, G., and Ladias, J. A. (2005) Structural basis for cell cycle checkpoint control by the BRCA1-CtIP complex. Biochemistry 44, 10941-10946.
-
(2005)
Biochemistry
, vol.44
, pp. 10941-10946
-
-
Varma, A.K.1
Brown, R.S.2
Birrane, G.3
Ladias, J.A.4
-
20
-
-
25444465151
-
Structure of the BRCT repeat domain of MDC1 and its specificity for the free COOH-terminal end of the gamma-H2AX histone tail
-
Lee, M. S., Edwards, R. A., Thede, G. L., and Glover, J. N. (2005) Structure of the BRCT repeat domain of MDC1 and its specificity for the free COOH-terminal end of the gamma-H2AX histone tail. J. Biol. Chem. 280, 32053-32056.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 32053-32056
-
-
Lee, M.S.1
Edwards, R.A.2
Thede, G.L.3
Glover, J.N.4
-
21
-
-
0037462647
-
Structural consequences of a cancer-causing BRCA1-BRCT missense mutation
-
Williams, R. S., and Glover, J. N. (2003) Structural consequences of a cancer-causing BRCA1-BRCT missense mutation. J. Biol. Chem. 278, 2630-2635.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 2630-2635
-
-
Williams, R.S.1
Glover, J.N.2
-
22
-
-
45749087347
-
-
Tischkowitz, M., Hamel, N., Carvalho, M. A., Birrane, G., Soni, A., van.Beers, E. H., Joosse, S. A., Wong, N., Novak, D., Quenneville, L. A., Grist, S. A., Nederlof, P. M., Goldgar, D. E., Tavtigian, S. V., Monteiro, A. N., Ladias, J. A. and, and Foulkes, W. D. (2008) Pathogenicity of the BRCA1 missense variant M1775K is determined by the disruption of the BRCT phosphopeptide- binding pocket: a multi-modal approach. Eur. J. Hum. Genet. (in press).
-
Tischkowitz, M., Hamel, N., Carvalho, M. A., Birrane, G., Soni, A., van.Beers, E. H., Joosse, S. A., Wong, N., Novak, D., Quenneville, L. A., Grist, S. A., Nederlof, P. M., Goldgar, D. E., Tavtigian, S. V., Monteiro, A. N., Ladias, J. A. and, and Foulkes, W. D. (2008) Pathogenicity of the BRCA1 missense variant M1775K is determined by the disruption of the BRCT phosphopeptide- binding pocket: a multi-modal approach. Eur. J. Hum. Genet. (in press).
-
-
-
-
23
-
-
0346101743
-
Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains
-
Rodriguez, M., Yu, X., Chen, J., and Songyang, Z. (2003) Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains. J. Biol. Chem. 278, 52914-52918.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 52914-52918
-
-
Rodriguez, M.1
Yu, X.2
Chen, J.3
Songyang, Z.4
-
24
-
-
34249950879
-
Ubiquitin-binding protein RAP80 mediates BRCA1-dependent DNA damage response
-
Kim, H., Chen, J., and Yu, X. (2007) Ubiquitin-binding protein RAP80 mediates BRCA1-dependent DNA damage response. Science 316, 1202-1205.
-
(2007)
Science
, vol.316
, pp. 1202-1205
-
-
Kim, H.1
Chen, J.2
Yu, X.3
-
25
-
-
0032792551
-
The ankyrin repeat: A diversity of interactions on a common structural framework
-
Sedgwick, S. G., and Smerdon, S. J. (1999) The ankyrin repeat: a diversity of interactions on a common structural framework. Trends Biochem. Sci. 24, 311-316.
-
(1999)
Trends Biochem. Sci
, vol.24
, pp. 311-316
-
-
Sedgwick, S.G.1
Smerdon, S.J.2
-
26
-
-
2442706456
-
The ankyrin repeat as molecular architecture for protein recognition
-
Mosavi, L. K., Cammett, T. J., Desrosiers, D. C., and Peng, Z. Y. (2004) The ankyrin repeat as molecular architecture for protein recognition. Protein Sci. 13, 1435-1448.
-
(2004)
Protein Sci
, vol.13
, pp. 1435-1448
-
-
Mosavi, L.K.1
Cammett, T.J.2
Desrosiers, D.C.3
Peng, Z.Y.4
-
27
-
-
36348986847
-
Structural requirements for the BARD1 tumor suppressor in chromosomal stability and homology-directed DNA repair
-
Laufer, M., Nandula, S. V., Modi, A. P., Wang, S., Jasin, M., Murty, V. V., Ludwig, T., and Baer, R. (2007) Structural requirements for the BARD1 tumor suppressor in chromosomal stability and homology-directed DNA repair. J. Biol. Chem. 282, 34325-34333.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 34325-34333
-
-
Laufer, M.1
Nandula, S.V.2
Modi, A.P.3
Wang, S.4
Jasin, M.5
Murty, V.V.6
Ludwig, T.7
Baer, R.8
-
28
-
-
2142721332
-
Mutations in the BRCA1-associated RING domain (BARD1) gene in primary breast, ovarian and uterine cancers
-
Thai, T. H., Du, F., Tsan, J. T., Jin, Y., Phung, A., Spillman, M. A., Massa, H. F., Muller, C. Y., Ashfaq, R., Mathis, J. M., Miller, D. S., Trask, B. J., Baer, R., and Bowcock, A. M. (1998) Mutations in the BRCA1-associated RING domain (BARD1) gene in primary breast, ovarian and uterine cancers. Hum. Mol. Genet. 7, 195-202.
-
(1998)
Hum. Mol. Genet
, vol.7
, pp. 195-202
-
-
Thai, T.H.1
Du, F.2
Tsan, J.T.3
Jin, Y.4
Phung, A.5
Spillman, M.A.6
Massa, H.F.7
Muller, C.Y.8
Ashfaq, R.9
Mathis, J.M.10
Miller, D.S.11
Trask, B.J.12
Baer, R.13
Bowcock, A.M.14
-
29
-
-
0036165866
-
Germline mutations of the BRCA1-associated ring domain (BARD1) gene in breast and breast/ovarian families negative for BRCA1 and BRCA2 alterations
-
Ghimenti, C., Sensi, E., Presciuttini, S., Brunetti, I. M., Conte, P., Bevilacqua, G., and Caligo, M. A. (2002) Germline mutations of the BRCA1-associated ring domain (BARD1) gene in breast and breast/ovarian families negative for BRCA1 and BRCA2 alterations. Genes Chromosomes Cancer 33, 235-242.
-
(2002)
Genes Chromosomes Cancer
, vol.33
, pp. 235-242
-
-
Ghimenti, C.1
Sensi, E.2
Presciuttini, S.3
Brunetti, I.M.4
Conte, P.5
Bevilacqua, G.6
Caligo, M.A.7
-
30
-
-
23744479222
-
Identification and characterization of missense alterations in the BRCA1 associated RING domain (BARD1) gene in breast and ovarian cancer
-
Sauer, M. K., and Andrulis, I. L. (2005) Identification and characterization of missense alterations in the BRCA1 associated RING domain (BARD1) gene in breast and ovarian cancer. J. Med. Genet. 42, 633-638.
-
(2005)
J. Med. Genet
, vol.42
, pp. 633-638
-
-
Sauer, M.K.1
Andrulis, I.L.2
-
31
-
-
18844407814
-
BRCA1/BARD1 inhibition of mRNA 3′ processing involves targeted degradation of RNA polymerase II
-
Kleiman, F. E., Wu-Baer, F., Fonseca, D., Kaneko, S., Baer, R., and Manley, J. L. (2005) BRCA1/BARD1 inhibition of mRNA 3′ processing involves targeted degradation of RNA polymerase II. Genes Dev. 19, 1227-1237.
-
(2005)
Genes Dev
, vol.19
, pp. 1227-1237
-
-
Kleiman, F.E.1
Wu-Baer, F.2
Fonseca, D.3
Kaneko, S.4
Baer, R.5
Manley, J.L.6
-
32
-
-
0035831030
-
The BARD1-CstF-50 interaction links mRNA 3′ end formation to DNA damage and tumor suppression
-
Kleiman, F. E., and Manley, J. L. (2001) The BARD1-CstF-50 interaction links mRNA 3′ end formation to DNA damage and tumor suppression. Cell 104, 743-753.
-
(2001)
Cell
, vol.104
, pp. 743-753
-
-
Kleiman, F.E.1
Manley, J.L.2
-
33
-
-
0001221269
-
Functional interaction of BRCA1-associated BARD1 with polyadenylation factor CstF-50
-
Kleiman, F. E., and Manley, J. L. (1999) Functional interaction of BRCA1-associated BARD1 with polyadenylation factor CstF-50. Science 285, 1576-1579.
-
(1999)
Science
, vol.285
, pp. 1576-1579
-
-
Kleiman, F.E.1
Manley, J.L.2
-
34
-
-
41849095683
-
The 3′ processing factor CstF functions in the DNA repair response
-
in press
-
Mirkin, N., Fonseca, D., Mohammed, S., Cevher, M. A., Manley, J. L., and Kleiman, F. E. (2008) The 3′ processing factor CstF functions in the DNA repair response. Nucleic Acids Res. (in press).
-
(2008)
Nucleic Acids Res
-
-
Mirkin, N.1
Fonseca, D.2
Mohammed, S.3
Cevher, M.A.4
Manley, J.L.5
Kleiman, F.E.6
-
35
-
-
0033984159
-
Complex protein interactions within the human polyadenylation machinery identify a novel component
-
Takagaki, Y., and Manley, J. L. (2000) Complex protein interactions within the human polyadenylation machinery identify a novel component. Mol. Cell. Biol. 20, 1515-1525.
-
(2000)
Mol. Cell. Biol
, vol.20
, pp. 1515-1525
-
-
Takagaki, Y.1
Manley, J.L.2
-
36
-
-
0000560808
-
MOLREP: An automated program for molecular replacement
-
Vagin, A., and Teplyakov, A. (1997) MOLREP: an automated program for molecular replacement. J. Appl. Crystallogr. 30, 1022-1025.
-
(1997)
J. Appl. Crystallogr
, vol.30
, pp. 1022-1025
-
-
Vagin, A.1
Teplyakov, A.2
-
37
-
-
0030924992
-
Refinement of macromolecular structures by the maximum-likelihood method
-
Murshudov, G. N., Vagin, A. A., and Dodson, E. J. (1997) Refinement of macromolecular structures by the maximum-likelihood method. Acta Crystallogr., Sect. D: Biol. Crystallogr. 53, 240-255.
-
(1997)
Acta Crystallogr., Sect. D: Biol. Crystallogr
, vol.53
, pp. 240-255
-
-
Murshudov, G.N.1
Vagin, A.A.2
Dodson, E.J.3
-
38
-
-
0035182073
-
Use of TLS parameters to model anisotropic displacements in macromolecular refinement
-
Winn, M., Isupov, M., and Murchudov, G. N. (2001) Use of TLS parameters to model anisotropic displacements in macromolecular refinement. Acta Crystallogr., Sect. D: Biol. Crystallogr. 57, 122-133.
-
(2001)
Acta Crystallogr., Sect. D: Biol. Crystallogr
, vol.57
, pp. 122-133
-
-
Winn, M.1
Isupov, M.2
Murchudov, G.N.3
-
39
-
-
3543012707
-
-
Brunger, A. T., Adams, P. D., Clore, G. M., DeLano, W. L., Gros, P., Grosse.Kunstleve, R. W., Jiang, J. S., Kuszewski, J., Nilges, M., Pannu, N. S., Read, R. J., Rice, L. M., Simonson, T., and Warren, G. L. (1998) Crystallography & NMR system: A new software suite for macromolecular structure determination. Acta Crystallogr., Sect. D: Biol. Crystallogr. 54, 905-921.
-
Brunger, A. T., Adams, P. D., Clore, G. M., DeLano, W. L., Gros, P., Grosse.Kunstleve, R. W., Jiang, J. S., Kuszewski, J., Nilges, M., Pannu, N. S., Read, R. J., Rice, L. M., Simonson, T., and Warren, G. L. (1998) Crystallography & NMR system: A new software suite for macromolecular structure determination. Acta Crystallogr., Sect. D: Biol. Crystallogr. 54, 905-921.
-
-
-
-
40
-
-
13244281317
-
Coot: Model-building tools for molecular graphics
-
Emsley, P., and Cowtan, K. (2004) Coot: model-building tools for molecular graphics. Acta Crystallogr., Sect. D: Biol. Crystallogr. 60, 2126-2132.
-
(2004)
Acta Crystallogr., Sect. D: Biol. Crystallogr
, vol.60
, pp. 2126-2132
-
-
Emsley, P.1
Cowtan, K.2
-
41
-
-
37149049312
-
X-ray solution scattering (SAXS) combined with crystallography and computation: Defining accurate macromolecular structures, conformations and assemblies in solution
-
Putnam, C. D., Hammel, M., Hura, G. L., and Tainer, J. A. (2007) X-ray solution scattering (SAXS) combined with crystallography and computation: defining accurate macromolecular structures, conformations and assemblies in solution. Q. Rev. Biophys. 40, 191-285.
-
(2007)
Q. Rev. Biophys
, vol.40
, pp. 191-285
-
-
Putnam, C.D.1
Hammel, M.2
Hura, G.L.3
Tainer, J.A.4
-
42
-
-
34248363563
-
Structural analysis of flexible proteins in solution by small angle X-ray scattering combined with crystallography
-
Tsutakawa, S. E., Hura, G. L., Frankel, K. A., Cooper, P. K., and Tainer, J. A. (2007) Structural analysis of flexible proteins in solution by small angle X-ray scattering combined with crystallography. J. Struct. Biol. 158, 214-223.
-
(2007)
J. Struct. Biol
, vol.158
, pp. 214-223
-
-
Tsutakawa, S.E.1
Hura, G.L.2
Frankel, K.A.3
Cooper, P.K.4
Tainer, J.A.5
-
43
-
-
0141484613
-
PRIMUS: A Windows PC-based system for small-angle scattering data analysis
-
Konarev, P. V., Volkov, V. V., Sokolova, A. V., Koch, M. H. J., and Svergun, D. I. (2003) PRIMUS: a Windows PC-based system for small-angle scattering data analysis. J. Appl. Crystallogr. 36, 1277-1282.
-
(2003)
J. Appl. Crystallogr
, vol.36
, pp. 1277-1282
-
-
Konarev, P.V.1
Volkov, V.V.2
Sokolova, A.V.3
Koch, M.H.J.4
Svergun, D.I.5
-
44
-
-
0026910457
-
Determination of the regularization parameter in indirect-transform methods using perceptual criteria
-
Svergun, D. I. (1992) Determination of the regularization parameter in indirect-transform methods using perceptual criteria. J. Appl. Crystallogr. 25, 495-503.
-
(1992)
J. Appl. Crystallogr
, vol.25
, pp. 495-503
-
-
Svergun, D.I.1
-
45
-
-
55249084786
-
-
Kikhney, A. G, Konarev, P. V, and Svergun, D. I
-
Kikhney, A. G., Konarev, P. V., and Svergun, D. I.
-
-
-
-
46
-
-
0033001996
-
Restoring low resolution structure of biological macromolecules from solution scattering using simulated annealing
-
Svergun, D. I. (1999) Restoring low resolution structure of biological macromolecules from solution scattering using simulated annealing. Biophys. J. 76, 2879-2886.
-
(1999)
Biophys. J
, vol.76
, pp. 2879-2886
-
-
Svergun, D.I.1
-
47
-
-
0035010533
-
Determination of domain structure of proteins from X-ray solution scattering
-
Svergun, D. I., Petoukhov, M. V., and Koch, M. H. (2001) Determination of domain structure of proteins from X-ray solution scattering. Biophys. J. 80, 2946-2953.
-
(2001)
Biophys. J
, vol.80
, pp. 2946-2953
-
-
Svergun, D.I.1
Petoukhov, M.V.2
Koch, M.H.3
-
48
-
-
0035124442
-
Automated matching of high- and low-resolution structural models
-
Kozin, M. B., and Svergun, D. I. (2001) Automated matching of high- and low-resolution structural models. J. Appl. Crystallogr. 34, 33-41.
-
(2001)
J. Appl. Crystallogr
, vol.34
, pp. 33-41
-
-
Kozin, M.B.1
Svergun, D.I.2
-
49
-
-
0037701585
-
Uniqueness of ab initio shape determination in small-angle scattering
-
Volkov, V. V., and Svergun, D. I. (2003) Uniqueness of ab initio shape determination in small-angle scattering. J. Appl. Crystallogr. 36, 860-864.
-
(2003)
J. Appl. Crystallogr
, vol.36
, pp. 860-864
-
-
Volkov, V.V.1
Svergun, D.I.2
-
50
-
-
0035747672
-
Enhancement of protein modeling by human intervention in applying the automatic programs 3D-JIGSAW and 3D-PSSM
-
Bates, P. A., Kelley, L. A., MacCallum, R. M., and Sternberg, M. J. (2001) Enhancement of protein modeling by human intervention in applying the automatic programs 3D-JIGSAW and 3D-PSSM. Proteins Suppl. 5, 39-46.
-
(2001)
Proteins Suppl
, vol.5
, pp. 39-46
-
-
Bates, P.A.1
Kelley, L.A.2
MacCallum, R.M.3
Sternberg, M.J.4
-
51
-
-
0032606088
-
Model building by comparison at CASP3: Using expert knowledge and computer automation
-
Bates, P. A., and Sternberg, M. J. (1999) Model building by comparison at CASP3: using expert knowledge and computer automation. Proteins Suppl. 3, 47-54.
-
(1999)
Proteins Suppl
, vol.3
, pp. 47-54
-
-
Bates, P.A.1
Sternberg, M.J.2
-
52
-
-
0036678447
-
Domain fishing: A first step in protein comparative modelling
-
Contreras-Moreira, B., and Bates, P. A. (2002) Domain fishing: a first step in protein comparative modelling. Bioinformatics 18, 1141-1142.
-
(2002)
Bioinformatics
, vol.18
, pp. 1141-1142
-
-
Contreras-Moreira, B.1
Bates, P.A.2
-
53
-
-
34247891557
-
Structural characterization of flexible proteins using small-angle X-ray scattering
-
Bernado, P., Mylonas, E., Petoukhov, M. V., Blackledge, M., and Svergun, D. I. (2007) Structural characterization of flexible proteins using small-angle X-ray scattering. J. Am. Chem. Soc. 129, 5656-5664.
-
(2007)
J. Am. Chem. Soc
, vol.129
, pp. 5656-5664
-
-
Bernado, P.1
Mylonas, E.2
Petoukhov, M.V.3
Blackledge, M.4
Svergun, D.I.5
-
54
-
-
0034809456
-
Crystal structure of the BRCT repeat region from the breast cancer-associated protein BRCA1
-
Williams, R. S., Green, R., and Glover, J. N. (2001) Crystal structure of the BRCT repeat region from the breast cancer-associated protein BRCA1. Nat. Struct. Biol. 8, 838-842.
-
(2001)
Nat. Struct. Biol
, vol.8
, pp. 838-842
-
-
Williams, R.S.1
Green, R.2
Glover, J.N.3
-
55
-
-
34347361679
-
Crystal structure of the BARD1 BRCT domains
-
Birrane, G., Varma, A. K., Soni, A., and Ladias, J. A. (2007) Crystal structure of the BARD1 BRCT domains. Biochemistry 46, 7706-7712.
-
(2007)
Biochemistry
, vol.46
, pp. 7706-7712
-
-
Birrane, G.1
Varma, A.K.2
Soni, A.3
Ladias, J.A.4
-
56
-
-
29244434544
-
MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks
-
Stucki, M., Clapperton, J. A., Mohammad, D., Yaffe, M. B., Smerdon, S. J., and Jackson, S. P. (2005) MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks. Cell 123, 1213-1226.
-
(2005)
Cell
, vol.123
, pp. 1213-1226
-
-
Stucki, M.1
Clapperton, J.A.2
Mohammad, D.3
Yaffe, M.B.4
Smerdon, S.J.5
Jackson, S.P.6
-
57
-
-
33646407280
-
DNA damage-induced BARD1 phosphorylation is critical for the inhibition of messenger RNA processing by BRCA1/BARD1 complex
-
Kim, H. S., Li, H., Cevher, M., Parmelee, A., Fonseca, D., Kleiman, F. E., and Lee, S. B. (2006) DNA damage-induced BARD1 phosphorylation is critical for the inhibition of messenger RNA processing by BRCA1/BARD1 complex. Cancer Res. 66, 4561-4565.
-
(2006)
Cancer Res
, vol.66
, pp. 4561-4565
-
-
Kim, H.S.1
Li, H.2
Cevher, M.3
Parmelee, A.4
Fonseca, D.5
Kleiman, F.E.6
Lee, S.B.7
-
59
-
-
0033621117
-
Compactness of the denatured state of a fast-folding protein measured by submillisecond small-angle x-ray scattering
-
Pollack, L., Tate, M. W., Darnton, N. C., Knight, J. B., Gruner, S. M., Eaton, W. A., and Austin, R. H. (1999) Compactness of the denatured state of a fast-folding protein measured by submillisecond small-angle x-ray scattering. Proc. Natl. Acad. Sci. U.S.A. 96, 10115-10117.
-
(1999)
Proc. Natl. Acad. Sci. U.S.A
, vol.96
, pp. 10115-10117
-
-
Pollack, L.1
Tate, M.W.2
Darnton, N.C.3
Knight, J.B.4
Gruner, S.M.5
Eaton, W.A.6
Austin, R.H.7
-
60
-
-
0035209087
-
Using Situs for the registration of protein structures with low-resolution bead models from X-ray solution scattering
-
Wriggers, W., and Chaon, P. (2001) Using Situs for the registration of protein structures with low-resolution bead models from X-ray solution scattering. J. Appl. Crystallogr. 34, 773-776.
-
(2001)
J. Appl. Crystallogr
, vol.34
, pp. 773-776
-
-
Wriggers, W.1
Chaon, P.2
-
61
-
-
18744380008
-
Consensus-derived structural determinants of the ankyrin repeat motif
-
Mosavi, L. K., Minor, D. L., Jr., and Peng, Z. Y. (2002) Consensus-derived structural determinants of the ankyrin repeat motif. Proc. Natl. Acad. Sci. U.S.A. 99, 16029-16034.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A
, vol.99
, pp. 16029-16034
-
-
Mosavi, L.K.1
Minor Jr., D.L.2
Peng, Z.Y.3
-
62
-
-
51049086890
-
Crystal structure of the BARD1 ankyrin repeat domain and its functional consequences
-
in press
-
Fox, D., Le Trong, I., Rajagopal, P., Brzovic, P. S., Stenkamp, R. E., and Klevit, R. E. (2008) Crystal structure of the BARD1 ankyrin repeat domain and its functional consequences. J. Biol. Chem. (in press).
-
(2008)
J. Biol. Chem
-
-
Fox, D.1
Le Trong, I.2
Rajagopal, P.3
Brzovic, P.S.4
Stenkamp, R.E.5
Klevit, R.E.6
-
64
-
-
38549146411
-
Structural characterization of the active and inactive states of Src kinase in solution by small-angle X-ray scattering
-
Bernado, P., Perez, Y., Svergun, D. I., and Pons, M. (2008) Structural characterization of the active and inactive states of Src kinase in solution by small-angle X-ray scattering. J. Mol. Biol. 376, 492-505.
-
(2008)
J. Mol. Biol
, vol.376
, pp. 492-505
-
-
Bernado, P.1
Perez, Y.2
Svergun, D.I.3
Pons, M.4
-
65
-
-
33749668010
-
A flexible interface between DNA ligase and PCNA supports conformational switching and efficient ligation of DNA
-
Pascal, J. M., Tsodikov, O. V., Hura, G. L., Song, W., Cotner, E. A., Classen, S., Tomkinson, A. E., Tainer, J. A., and Ellenberger, T. (2006) A flexible interface between DNA ligase and PCNA supports conformational switching and efficient ligation of DNA. Mol. Cell 24, 279-291.
-
(2006)
Mol. Cell
, vol.24
, pp. 279-291
-
-
Pascal, J.M.1
Tsodikov, O.V.2
Hura, G.L.3
Song, W.4
Cotner, E.A.5
Classen, S.6
Tomkinson, A.E.7
Tainer, J.A.8
Ellenberger, T.9
-
66
-
-
34248579736
-
The N terminus of Saccharomyces cerevisiae Msh6 is an unstructured tether to PCNA
-
Shell, S. S., Putnam, C. D., and Kolodner, R. D. (2007) The N terminus of Saccharomyces cerevisiae Msh6 is an unstructured tether to PCNA. Mol. Cell 26, 565-578.
-
(2007)
Mol. Cell
, vol.26
, pp. 565-578
-
-
Shell, S.S.1
Putnam, C.D.2
Kolodner, R.D.3
-
67
-
-
0030297912
-
Crystal structure at 2.4 angstroms resolution of the complex of transducin betagamma and its regulator, phosducin
-
Gaudet, R., Bohm, A., and Sigler, P. B. (1996) Crystal structure at 2.4 angstroms resolution of the complex of transducin betagamma and its regulator, phosducin. Cell 87, 577-588.
-
(1996)
Cell
, vol.87
, pp. 577-588
-
-
Gaudet, R.1
Bohm, A.2
Sigler, P.B.3
-
68
-
-
0029593456
-
The structure of the G protein heterotrimer Gi alpha 1 beta 1 gamma 2
-
Wall, M. A., Coleman, D. E., Lee, E., Iniguez-Lluhi, J. A., Posner, B. A., Gilman, A. G., and Sprang, S. R. (1995) The structure of the G protein heterotrimer Gi alpha 1 beta 1 gamma 2. Cell 83, 1047-1058.
-
(1995)
Cell
, vol.83
, pp. 1047-1058
-
-
Wall, M.A.1
Coleman, D.E.2
Lee, E.3
Iniguez-Lluhi, J.A.4
Posner, B.A.5
Gilman, A.G.6
Sprang, S.R.7
-
69
-
-
0042738069
-
Full-length archaeal Rad51 structure and mutants: Mechanisms for RAD51 assembly and control by BRCA2
-
Shin, D. S., Pellegrini, L., Daniels, D. S., Yelent, B., Craig, L., Bates, D., Yu, D. S., Shivji, M. K., Hitomi, C., Arvai, A. S., Volkmann, N., Tsuruta, H., Blundell, T. L., Venkitaraman, A. R., and Tainer, J. A. (2003) Full-length archaeal Rad51 structure and mutants: mechanisms for RAD51 assembly and control by BRCA2. EMBO J. 22, 4566-4576.
-
(2003)
EMBO J
, vol.22
, pp. 4566-4576
-
-
Shin, D.S.1
Pellegrini, L.2
Daniels, D.S.3
Yelent, B.4
Craig, L.5
Bates, D.6
Yu, D.S.7
Shivji, M.K.8
Hitomi, C.9
Arvai, A.S.10
Volkmann, N.11
Tsuruta, H.12
Blundell, T.L.13
Venkitaraman, A.R.14
Tainer, J.A.15
-
70
-
-
0035878112
-
Capping, splicing, and 3′ processing are independently stimulated by RNA polymerase II: Different functions for different segments of the CTD
-
Fong, N., and Bentley, D. L. (2001) Capping, splicing, and 3′ processing are independently stimulated by RNA polymerase II: different functions for different segments of the CTD. Genes Dev. 15, 1783-1795.
-
(2001)
Genes Dev
, vol.15
, pp. 1783-1795
-
-
Fong, N.1
Bentley, D.L.2
-
71
-
-
0031037856
-
The C-terminal domain of RNA polymerase II couples mRNA processing to transcription
-
McCracken, S., Fong, N., Yankulov, K., Ballantyne, S., Pan, G., Greenblatt, J., Patterson, S. D., Wickens, M., and Bentley, D. L. (1997) The C-terminal domain of RNA polymerase II couples mRNA processing to transcription. Nature 385, 357-361.
-
(1997)
Nature
, vol.385
, pp. 357-361
-
-
McCracken, S.1
Fong, N.2
Yankulov, K.3
Ballantyne, S.4
Pan, G.5
Greenblatt, J.6
Patterson, S.D.7
Wickens, M.8
Bentley, D.L.9
-
72
-
-
3843066731
-
BRCA1-BARD1 complexes are required for p53Ser-15 phosphorylation and a G1/S arrest following ionizing radiation-induced DNA damage
-
Fabbro, M., Savage, K., Hobson, K., Deans, A. J., Powell, S. N., McArthur, G. A., and Khanna, K. K. (2004) BRCA1-BARD1 complexes are required for p53Ser-15 phosphorylation and a G1/S arrest following ionizing radiation-induced DNA damage. J. Biol. Chem. 279, 31251-31258.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 31251-31258
-
-
Fabbro, M.1
Savage, K.2
Hobson, K.3
Deans, A.J.4
Powell, S.N.5
McArthur, G.A.6
Khanna, K.K.7
-
73
-
-
19844373870
-
BARD1 induces apoptosis by catalysing phosphorylation of p53 by DNA-damage response kinase
-
Feki, A., Jefford, C. E., Berardi, P., Wu, J. Y., Cartier, L., Krause, K. H., and Irminger-Finger, I. (2005) BARD1 induces apoptosis by catalysing phosphorylation of p53 by DNA-damage response kinase. Oncogene 24, 3726-3736.
-
(2005)
Oncogene
, vol.24
, pp. 3726-3736
-
-
Feki, A.1
Jefford, C.E.2
Berardi, P.3
Wu, J.Y.4
Cartier, L.5
Krause, K.H.6
Irminger-Finger, I.7
-
74
-
-
18244399879
-
Identification of BARD1 as mediator between proapoptotic stress and p53-dependent apoptosis
-
Irminger-Finger, I., Leung, W. C., Li, J., Dubois-Dauphin, M., Harb, J., Feki, A., Jefford, C. E., Soriano, J. V., Jaconi, M., Montesano, R., and Krause, K. H. (2001) Identification of BARD1 as mediator between proapoptotic stress and p53-dependent apoptosis. Mol. Cell 8, 1255-1266.
-
(2001)
Mol. Cell
, vol.8
, pp. 1255-1266
-
-
Irminger-Finger, I.1
Leung, W.C.2
Li, J.3
Dubois-Dauphin, M.4
Harb, J.5
Feki, A.6
Jefford, C.E.7
Soriano, J.V.8
Jaconi, M.9
Montesano, R.10
Krause, K.H.11
-
75
-
-
34247157961
-
Developing master keys to brain pathology, cancer and aging from the structural biology of proteins controlling reactive oxygen species and DNA repair
-
Perry, J. J., Fan, L., and Tainer, J. A. (2007) Developing master keys to brain pathology, cancer and aging from the structural biology of proteins controlling reactive oxygen species and DNA repair. Neuroscience 145, 1280-1299.
-
(2007)
Neuroscience
, vol.145
, pp. 1280-1299
-
-
Perry, J.J.1
Fan, L.2
Tainer, J.A.3
|