Nifedipine suppresses Th1/Th2 cytokine production and increased apoptosis of anti-CD3 + anti-CD28-activated mononuclear cells from patients with systemic lupus erythematosus via calcineurin pathway

Clinical Immunology

Volumn 129, Issue 3, 2008, Pages 462-470

  Lu, Ming Chi ^a,b,c   Lai, Ning Sheng ^a,c   Yu, Hui Chun ^a   Hsieh, Song Chou ^d   Tung, Chien Hsueh ^a   Yu, Chia Li ^d  

^a BUDDHIST TZU CHI GENERAL HOSPITAL   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^c TZU CHI UNIVERSITY   (Taiwan)

^d NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Apoptosis; ; Calcineurin; ; Calcium channel blocker; ; Mononuclear cells; ; Nifedipine; Systemic lupus erythematosus;

Indexed keywords

CALCINEURIN; CALCINEURIN INHIBITOR; CALCIUM CHANNEL L TYPE; CD28 ANTIGEN; CD3 ANTIBODY; FAS LIGAND; GAMMA INTERFERON; INTERLEUKIN 10; NIFEDIPINE; PHOSPHATASE;

ADULT; APOPTOSIS; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN CELL; MALE; MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYSTEMIC LUPUS ERYTHEMATOSUS; TH1 CELL; TH2 CELL;

ADULT; ANTIGENS, CD28; ANTIGENS, CD3; APOPTOSIS; CALCINEURIN; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, L-TYPE; CYTOKINES; FAS LIGAND PROTEIN; FEMALE; HUMANS; INTERFERON-GAMMA; INTERLEUKIN-10; LEUKOCYTES, MONONUCLEAR; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; NFATC TRANSCRIPTION FACTORS; NIFEDIPINE; PHOSPHORIC MONOESTER HYDROLASES; SIGNAL TRANSDUCTION;

EID: 55249083269     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2008.08.001     Document Type: Article

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