The apoptotic ligands TRAIL, TWEAK, and fas ligand mediate monocyte death induced by autologous lupus T cells

Journal of Immunology

Volumn 169, Issue 10, 2002, Pages 6020-6029

  Kaplan, Mariana J ^a   Lewis, Emily E ^a   Shelden, Eric A ^a   Somers, Emily ^a   Pavlic, Robert ^a   McCune, William J ^a   Richardson, Bruce C ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL AGENT; AZATHIOPRINE; CYCLOPHOSPHAMIDE; FAS LIGAND; METHOTREXATE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; TUMOR NECROSIS FACTOR LIKE WEAK INDUCER OF APOPTOSIS LIGAND; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG;

ANTIGENICITY; APOPTOSIS; ARTICLE; AUTOIMMUNITY; CELL DEATH; CELL SUBPOPULATION; CONTROLLED STUDY; CYTOTOXICITY; DISEASE ACTIVITY; FEMALE; HUMAN; HUMAN CELL; IMMUNE RESPONSE; LIGAND BINDING; LYMPHOCYTE ACTIVATION; MAJOR CLINICAL STUDY; MALE; MONOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYSTEMIC LUPUS ERYTHEMATOSUS; T LYMPHOCYTE;

EID: 0037111246     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.169.10.6020     Document Type: Article

References (53)

1. Emlen, W., J. Niebur, and R. Kadera. 1994. Accelerated in vitro apoptosis of lymphocytes from patients with systemic lupus erythematosus. J. Immunol. 152: 3685.
2. Pemiok, A., F. Weedkind, M. Hermann, C. Specker, and M. Schneider. 1998. High levels of circulating early apoptotic peripheral blood mononuclear cells in systemic lupus erythematosus. Lupus 7:113.
3. Mysler, E., P. Bini, J. Drappa, P. Ramos, S. M. Friedman, P. H. Krammer, and K. B. Elkon. 1994. The apoptosis-1/Fas protein in human systemic lupus erythematosus. J. Clin. Invest. 93:1029.
4. Yang, B. C., Y. S. Wang, L. C. Lin, and M. F. Liu. 1997. Induction of apoptosis and cytokine gene expression in T cell lines by sera of patients with systemic lupus erythematosus. Scand. J. Immunol. 45:96.
5. Bell, D. A., and B. Morrison. 1991. The spontaneous apoptotic death of normal human lymphocytes in vitro: The release of an immunoproliferative response to nucleosomes in vitro. Clin. Immunol. Immunopathol. 60:13.
6. Chan, E. Y., S. C. Ko, and C. S. Lau. 1997. Increased rate of apoptosis and decreased expression of bcl-2 protein in peripheral blood lymphocytes from patients with active systemic lupus erythematosus. Asian Pac. J. Allergy Immunol. 15:3.
7. Richardson, B., R. Yung, P. Rowse, K. Johnson, and N. D. Lalwani. 1993. Monocyte apoptosis in patients with active lupus. Arthritis Rheum. 39:1432.
8. Shoshan, Y., I. Shapira, E. Toubi, I. Frolkis, M. Yaron, and D. Mevorach. 2001. Accelerated Fas-mediated apoptosis of monocytes and maturing macrophages from patients with systemic lupus erythematosus: Relevance to in vitro impairment of interaction with iC3b-opsonized apoptotic cells. J. Immunol. 167:5963.
9. Richardson, B. C., J. R. Strahler, T. S. Pivirotto, J. Quddus, G. E. Bayliss, L. A. Gross, K. S. O'Rourke, D. J. Powers, S. M. Hanash, and M. A. Johnson. 1992. Phenotypic and functional similarities between 5-azacytidine treated T cells and a T cell subset in patients with active systemic lupus erythematosus. Arthritis Rheum. 35:647.
10. + T cell killing of antigen-presenting macrophages. J. Immunol. 164:2897.
11. Yung, R., M. Kaplan, D. Ray, K. Schneider, R.-R. Mo, K. Johnson, and B. Richardson. 2001. Autoreactive murine Th1 and Th2 cells kill syngeneic macrophages and induce autoantibodies. Lupus 10:539.
12. Wiley, S. R., L. Cassiano, T. Lofton, T. Davis-Smith, J. A. Winkles, V. Linder, H. Liu, T. O. Daniel, C. A. Smith, and W. C. Fanslow. 2001. A novel TNF receptor family member binds TWEAK and is implicated in angiogenesis. Immunity 15:837.
13. Tan, E. M., A. S. Cohen. J. F. Fries, A. T. Masi, D. J. McShane, N. F. Rothfield, J. G. Schaller, N. Talal, and R. J. Winchester. 1982. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum. 25:1271.
14. Arnett, F. C., S. M. Edworthy, D. A. Bloch, D. J. McShane, J. F. Fries, N. S. Cooper, L. A. Healey, S. R. Kaplan, M. H. Liang, H. S. Luthra, et al. 1988. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum. 31:315.
15. Bombardier, C., D. D. Gladman, M. B. Urowitz, D. Caron, and C. H. Chang. 1992. Derivation of the SLEDAI: A disease activity index for lupus patients. Arthritis Rheum. 35:630.
16. Gabriel, S. E., C. S. Crowson, and W. M. O'Fallon. 1999. The epidemiology of rheumatoid arthritis in Rochester, MN, 1955-1985. Arthritis Rheum. 42:415.
17. Ramakrishnan, S., and L. L. Houston. 1984. Inhibition of human acute lymphoblastic leukemia cells by immunotoxins: Potentiation by chloroquine. Science 223:58.
18. Kerkhoff, C., L. Gehring, K. Habben, K. Resch, and V. Kaever. 1997. The mitogen-induced lysophospholipid: Acyl-coA acyltransferase (LAT) expression of human T-lymphocytes is diminished by hydrocortisone. Biochem. Biophys. Res. Commun. 237:632.
19. Lieberman, M. M., G. M. Patterson, and R. E. Moore. 2001. In vitro bioassays for anticancer drug screening: Effects of cell concentration and other assay parameters on growth inhibitory activity. Cancer Lett. 173:21.
20. Nakayama, M., N. Kayagaki, N. Yamaguchi, K. Okumura, and H. Yagita. 2000. Involvement of TWEAK in interferon γ-stimulated monocyte cytotoxicity. J. Exp. Med. 192:1373.
21. Michea, L., C. Combs, P. Andrews, N. Dmitrieva, and M. B. Burg. 2002. Mitochondrial dysfunction is an early event in high-NaCl-induced apoptosis of mIMCD3 cells. Am. J. Physiol. Renal Physiol. 282:F981.
22. Cory, A. H., T. C. Owen, J. A. Barltrop, and J. G. Cory. 1991. Use of an aqueous soluble tetrazolium/formazan assay for cell growth assays in culture. Cancer Commun. 3:207.
23. Hynes, R. O. 1992. Integrins: Versatility, modulation, and signaling in cell adhesion. Cell 69:11.
24. Kovacs, B., S. N. Liossis, G. J. Dennis, and G. C. Tsokos. 1997. Increased expression of functional Fas-ligand in activated T cells from systemic lupus erythematosus. Autoimmunity 25:213.
25. Los, M., M. Mozoluk, D. Ferrari, A. Stepczynska, C. Stroh, A. Renz, Z. Herceg, Z. Q. Wang, and K. Schulze-Osthoff. 2002. Activation and caspase-mediated inhibition of PARP: A molecular switch between fibroblast necrosis and apoptosis in death receptor signaling. Mol. Cell. Biol. 13:978.
26. Chou, A. H., H. F. Tsai, L. L. Lin, S. L. Hsieh, P. I. Hsu, and P. N. Hsu. 2001. Enhanced proliferation and increased IFN-γ production in T cells by signal transduced through TNF-related apoptosis-inducing ligand. J. Immunol. 167:1347.
27. Lehner, M., T. Felzmann, K. Clodi, and W. Holter. 2001. Type I interferons in combination with bacterial stimuli induce apoptosis of monocyte-derived dendritic cells. Blood 98:736.
28. Wang, Z. Q., A. S. Bapat, R. J. Rayanade, A. S. Dagtas, and M. K. Hoffmann. 2001. Interleukin-10 induces macrophage apoptosis and expression of CD16 (FcγRIII) whose engagement blocks the cell death programme and facilitates differentiation. Immunology 102:331.
29. Schmidt, M., N. Lugering, H. G. Pauels, K. Schulze-Osthoff, W. Domschke, and T. Kucharzik. 2000. IL-10 induces apoptosis in human monocytes involving the CD95 receptor/ligand pathway. Eur. J. Immunol. 30:1769.
30. Lang, D., A. Hubrich, F. Dohle, M. Terstesse, H. Saleh, M. Schmidt, H. G. Pauels, and S. Heidenreich. 2000. Differential expression of heat shock protein 70 (hsp70) in human monocytes rendered apoptotic by IL-4 or serum deprivation. J. Leukocyte Biol. 68:729.
31. + T cells. Eur. J. Immunol. 23:1450.
32. + T cells during the anti-tumour effects of targeted superantigens. Br. J. Cancer 81:359.
33. + T cells. J. Virol. 72:4387.
34. + T cells. J. Immunol. 159:2091.
35. Al-Janadi, M., and S. Raziuddin. 1993. B cell hyperactivity is a function of T cell derived cytokines in systemic lupus erythematosus. J. Rheumatol. 20:1885.
36. Mariani, S. M., and P. H. Krammer. 1998. Surface expression of TRAIL/Apo2 ligand in activated mouse T and B cells. Eur. J. Immunol. 28:1492.
37. Jo, M., T. H. Kim, D. W. Seol, J. E. Esplen, K. Dorko, T. R. Billiar, and S. C. Strom. 2000. Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand. Nat. Med. 6:564.
38. Nitsch, R., I. Bechmann, R. A. Deisz, D. Haas, T. N. Lehmann, U. Wendling, and F. Zipp. 2000. Human brain-cell death induced by tumour-necrosis-factor-related apoptosis-inducing ligand (TRAIL). Lancet 356:827.
39. Martinez-Lorenzo, M. J., M. A. Alava, S. Garmen, K. J. Kim, A. Chuntherapai, A. Pineiro, J. Naval, and A. Anel. 1998. Involvement of Apo2 ligand/TRAIL in activation-induced death of Jurkat and human peripheral blood T cells. Eur. J. Immunol. 28:2714.
40. Golstein, P. 1997. Cell death: TRAIL and its receptors. Curr. Biol. 7:R750.
41. Herr, I., C. Posovszky, L. D. Di Marzio, M. G. Cifone, T. Boehler, and K. M. Debatin. 2000. Autoamplification of apoptosis following ligation of CD95L, TRAIL and TNF-α. Oncogene 19:4255.
42. Snell, V., K. Clodi, S. Zhao, R. Goodwin, E. K. Thomas, S. W. Morris, M. E. Kadin, F. Cabanillas, M. Andreeff, and A. Younes. 1997. Activity of TNF-related apoptosis-inducing ligand (TRAIL) in haematological malignancies. Br. J. Haematol. 99:618.
43. + T cell subsets against keratinocytes. J. Immunol. 165:2058.
44. Klint, C., L. Truedsson, A. Andreasson, I. Johansson, and G. Sturfelt. 2000. Toxic effects of SLE serum on normal monocytes in vitro: Cell death induced by apoptosis related to complement dysfunction. Lupus 9:278.
45. Kaplan, M., L. Beretta, R. L. Yung, and B. C. Richardson. 2000. LFA-1 overexpression and T cell autoreactivity: Mechanisms. Immunol. Invest. 29:427.
46. Savill, J. 1997. Recognition and phagocytosis of cells undergoing apoptosis. Br. Med. Bull. 53:491.
47. Savill, J., Y. Ren, H. Church, S. Loizou, M. J. Walport, and S. A. Brown. 1997. A new candidate mechanism for tissue injury in autoimmunity: Autoantibodies that bind apoptotic cells block clearance by macrophages. J. Am. Soc. Nephrol. 8:484A.
48. Hermann, M., R. E. Voll, and J. R. Kalden. 2000. Etiopathogenesis of systemic lupus erythematosus. Immunol. Today 21:424.
49. Albert, M. L., B. Sauter, and N. Bhardwaj. 1998. Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs. Nature 392:86.
50. Huynh, M. L. N., V. A. Fadok, and P. M. Henson. 2002. Phosphatidylserinedependent ingestion of apoptotic cells promotes TGF-β1 secretion and the resolution of inflammation. J. Clin. Invest. 109:41.
51. Bave, U., G. V. Alm, and L. Ronnblom. 2000. The combination of apoptotic U937 cells and lupus IgG is a potent IFN-α inducer. J. Immunol. 165:3519.
52. Blanco, P., A. K. Palucka, M. Gill, V. Pascual, and J. Banchereau. 2001. Induction of dendritic cell differentiation by IFN-α in systemic lupus erythematosus. Science 294:1540.
53. Kayagaki, N., N. Yamaguchi, M. Nakayama, H. Eto, K. Okumura, and H. Yagita. 1999. Type I interferons (IFNs) regulate tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) expression on human T cells: A novel mechanism for the antitumor effects of type I IFNs. J. Exp. Med. 189:1451.