Modulation of the BCL-2/BAX ratio by interferon-γ and hypoxia in human peritoneal and adhesion fibroblasts

Fertility and Sterility

Volumn 90, Issue 5, 2008, Pages 1925-1930

  Saed, Ghassan M ^a   Jiang, Zhongliang ^a   Fletcher, Nicole M ^a   Diamond, Michael P ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

apoptosis; BCL 2 BAX ratio; hypoxia; interferon ; Postoperative adhesions

Indexed keywords

GAMMA INTERFERON; PROTEIN BAX; PROTEIN BCL 2;

APOPTOSIS; ARTICLE; CELL LINE; CONTROLLED STUDY; DNA SYNTHESIS; DOSE RESPONSE; DRUG EFFICACY; FIBROBLAST; FIBROBLAST CULTURE; FIBROSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOXIA; MULTIPLEX POLYMERASE CHAIN REACTION; PERITONEUM; PERITONEUM ADHESION; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN EXPRESSION; PROTEIN TARGETING;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELL HYPOXIA; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBROBLASTS; HUMANS; INTERFERON-GAMMA; PERITONEAL DISEASES; PERITONEUM; PROSPECTIVE STUDIES; PROTO-ONCOGENE PROTEINS C-BCL-2; RNA, MESSENGER; TIME FACTORS; TISSUE ADHESIONS;

EID: 55149099204     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2007.06.091     Document Type: Article

References (55)

1. Heemken R., Gandawidjaja L., and Hau T. Peritonitis: pathophysiology and local defense mechanisms. Hepatogastroenterology 44 (1997) 927-936
2. Diamond M.P., and El-Mowafi D.M. Pelvic adhesions. Surg Technol Int VII (1998) 273-283
3. Saed G.M., and Diamond M.P. Molecular characterization of postoperative adhesions: the adhesion phenotype. J Am Assoc Gynecol Laparosc 11 (2004) 307-314
4. Alpay Z., Saed G.M., and Diamond M.P. Female infertility and free radicals: potential role in adhesions and endometriosis. J Soc Gynecol Investig 13 (2006) 390-398
5. Saed G.M., Kruger M., and Diamond M.P. Expression of transforming growth factor-beta and extracellular matrix by human peritoneal mesothelial cells and by fibroblasts from normal peritoneum and adhesions: effect of Tisseel. Wound Repair Regen 12 (2004) 557-564
6. Friedman S.L. Stellate cell activation in alcoholic fibrosis-an overview. Alcohol Clin Exp Res 23 (1999) 904-910
7. Adesida A.B., Grady L.M., Khan W.S., and Hardingham T.E. The matrix-forming phenotype of cultured human meniscus cells is enhanced after culture with fibroblast growth factor 2 and is further stimulated by hypoxia. Arthritis Res Ther 8 (2006) R61
8. Norman J.T., Orphanides C., Garcia P., and Fine L.G. Hypoxia-induced changes in extracellular matrix metabolism in renal cells. Exp Nephrol 7 (1999) 463-469
9. Saed G.M., and Diamond M.P. Effects of interferon-gamma reverse hypoxia-stimulated extracellular matrix expression in human peritoneal and adhesion fibroblasts. Fertil Steril 85 Suppl 1 (2006) 1300-1305
10. Saed G.M., Munkarah A.R., Abu-Soud H.M., and Diamond M.P. Hypoxia upregulates cyclooxygenase-2 and prostaglandin E(2) levels in human peritoneal fibroblasts. Fertil Steril 83 Suppl 1 (2005) 1216-1219
11. Saed G.M., and Diamond M.P. Modulation of the expression of tissue plasminogen activator and its inhibitor by hypoxia in human peritoneal and adhesion fibroblasts. Fertil Steril 79 (2003) 164-168
12. Saed G.M., and Diamond M.P. Hypoxia-induced irreversible up-regulation of type I collagen and transforming growth factor-beta1 in human peritoneal fibroblasts. Fertil Steril 78 (2002) 144-147
13. Saed G.M., and Diamond M.P. Differential expression of alpha smooth muscle cell actin in human fibroblasts isolated from intraperitoneal adhesions and normal peritoneal tissues. Fertil Steril 82 Suppl 3 (2004) 1188-1192
14. Darby I.A., and Hewitson T.D. Fibroblast differentiation in wound healing and fibrosis. Int Rev Cytol 257 (2007) 143-179
15. Saed G.M., and Diamond M.P. Apoptosis and proliferation of human peritoneal fibroblasts in response to hypoxia. Fertil Steril 78 (2002) 137-143
16. Boehm U., Klamp T., Groot M., and Howard J.C. Cellular responses to interferon-gamma. Annu Rev Immunol 15 (1997) 749-795
17. Stark G.R., Kerr I.M., Williams B.R., Silverman R.H., and Schreiber R.D. How cells respond to interferons. Annu Rev Biochem 67 (1998) 227-264
18. Koshiji M., Adachi Y., Sogo S., Taketani S., Oyaizu N., Than S., et al. Apoptosis of colorectal adenocarcinoma (COLO 201) by tumour necrosis factor-alpha (TNF-alpha) and/or interferon-gamma (IFN-gamma), resulting from down-modulation of Bcl-2 expression. Clin Exp Immunol 111 (1998) 211-218
19. Kim C.J., Taubenberger J.K., Simonis T.B., White D.E., Rosenberg S.A., and Marincola F.M. Combination therapy with interferon-gamma and interleukin-2 for the treatment of metastatic melanoma. J Immunother Emphasis Tumor Immunol 19 (1996) 50-58
20. Schindler C. STATs as activators of apoptosis. Trends Cell Biol 8 (1998) 97-98
21. Saed G.M., Zhang W., and Diamond M.P. Molecular characterization of fibroblasts isolated from human peritoneum and adhesions. Fertil Steril 75 (2001) 763-768
22. Saed G.M., Zhang W., Chegini N., Holmdahl L., and Diamond M.P. Alteration of type I and III collagen expression in human peritoneal mesothelial cells in response to hypoxia and transforming growth factor-beta1. Wound Repair Regen 7 (1999) 504-510
23. Saed G.M., and Diamond M.P. Effect of glucose on the expression of type I collagen and transforming growth factor-beta1 in cultured human peritoneal fibroblasts. Fertil Steril 79 (2003) 158-163
24. Feugate J.E., Li Q., Wong L., and Martins-Green M. The cxc chemokine cCAF stimulates differentiation of fibroblasts into myofibroblasts and accelerates wound closure. J Cell Biol 156 (2002) 161-172
25. Rosenkranz S. TGF-beta1 and angiotensin networking in cardiac remodeling. Cardiovasc Res 63 (2004) 423-432
26. Roy S., Khanna S., Bickerstaff A.A., Subramanian S.V., Atalay M., Bierl M., et al. Oxygen sensing by primary cardiac fibroblasts: a key role of p21(Waf1/Cip1/Sdi1). Circ Res 92 (2003) 264-271
27. Siwik D.A., Pagano P.J., and Colucci W.S. Oxidative stress regulates collagen synthesis and matrix metalloproteinase activity in cardiac fibroblasts. Am J Physiol Cell Physiol 280 (2001) C53-C60
28. Cucoranu I., Clempus R., Dikalova A., Phelan P.J., Ariyan S., Dikalov S., et al. NAD(P)H oxidase 4 mediates transforming growth factor-beta1-induced differentiation of cardiac fibroblasts into myofibroblasts. Circ Res 97 (2005) 900-907
29. Olson E.R., Naugle J.E., Zhang X., Bomser J.A., and Meszaros J.G. Inhibition of cardiac fibroblast proliferation and myofibroblast differentiation by resveratrol. Am J Physiol Heart Circ Physiol 288 (2005) H1131-H1138
30. Garban H.J., and Bonavida B. Nitric oxide disrupts H2O2-dependent activation of nuclear factor kappa B. Role in sensitization of human tumor cells to tumor necrosis factor-alpha-induced cytotoxicity. J Biol Chem 276 (2001) 8918-8923
31. Moreau R. Are nitric oxide synthases new players in the pathophysiology of fulminant hepatic failure?. J Hepatol 37 (2002) 678-680
32. Golstein P. Controlling cell death. Science 275 (1997) 1081-1082
33. Kim Y.M., de Vera M.E., Watkins S.C., and Billiar T.R. Nitric oxide protects cultured rat hepatocytes from tumor necrosis factor-alpha-induced apoptosis by inducing heat shock protein 70 expression. J Biol Chem 272 (1997) 1402-1411
34. Mosser D.D., Caron A.W., Bourget L., Denis-Larose C., and Massie B. Role of the human heat shock protein hsp70 in protection against stress-induced apoptosis. Mol Cell Biol 17 (1997) 5317-5327
35. Jolly C., and Morimoto R.I. Role of the heat shock response and molecular chaperones in oncogenesis and cell death. J Natl Cancer Inst 92 (2000) 1564-1572
36. Der S.D., Zhou A., Williams B.R., and Silverman R.H. Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays. Proc Natl Acad Sci U S A 95 (1998) 15623-15628
37. Spanaus K.S., Schlapbach R., and Fontana A. TNF-alpha and IFN-gamma render microglia sensitive to Fas ligand-induced apoptosis by induction of Fas expression and down-regulation of Bcl-2 and Bcl-xL. Eur J Immunol 28 (1998) 4398-4408
38. Ossina N.K., Cannas A., Powers V.C., Fitzpatrick P.A., Knight J.D., Gilbert J.R., et al. Interferon-gamma modulates a p53-independent apoptotic pathway and apoptosis-related gene expression. J Biol Chem 272 (1997) 16351-16357
39. Desmouliere A., Darby I.A., and Gabbiani G. Normal and pathologic soft tissue remodeling: role of the myofibroblast, with special emphasis on liver and kidney fibrosis. Lab Invest 83 (2003) 1689-1707
40. Virag J.I., and Murry C.E. Myofibroblast and endothelial cell proliferation during murine myocardial infarct repair. Am J Pathol 163 (2003) 2433-2440
41. Brown R.D., Ambler S.K., Mitchell M.D., and Long C.S. The cardiac fibroblast: therapeutic target in myocardial remodeling and failure. Annu Rev Pharmacol Toxicol 45 (2005) 657-687
42. Phan S.H. The myofibroblast in pulmonary fibrosis. Chest 122 (2002) 286S-289S
43. Thannickal V.J., Toews G.B., White E.S., Lynch III J.P., and Martinez F.J. Mechanisms of pulmonary fibrosis. Annu Rev Med 55 (2004) 395-417
44. Lan H.Y. Tubular epithelial-myofibroblast transdifferentiation mechanisms in proximal tubule cells. Curr Opin Nephrol Hypertens 12 (2003) 25-29
45. Desmouliere A., Redard M., Darby I., and Gabbiani G. Apoptosis mediates the decrease in cellularity during the transition between granulation tissue and scar. Am J Pathol 146 (1995) 56-66
46. Pittet B., Rubbia-Brandt L., Desmouliere A., Sappino A.P., Roggero P., Guerret S., et al. Effect of gamma-interferon on the clinical and biologic evolution of hypertrophic scars and Dupuytren's disease: an open pilot study. Plast Reconstr Surg 93 (1994) 1224-1235
47. Mallat A., Preaux A.M., Blazejewski S., Rosenbaum J., Dhumeaux D., and Mavier P. Interferon alfa and gamma inhibit proliferation and collagen synthesis of human Ito cells in culture. Hepatology 21 (1995) 1003-1010
48. Desmouliere A. Factors influencing myofibroblast differentiation during wound healing and fibrosis. Cell Biol Int 19 (1995) 471-476
49. Chao D.T., and Korsmeyer S.J. BCL-2 family: regulators of cell death. Annu Rev Immunol 16 (1998) 395-419
50. Chinnaiyan A.M., O'Rourke K., Lane B.R., and Dixit V.M. Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death. Science 275 (1997) 1122-1126
51. Oltvai Z.N., Milliman C.L., and Korsmeyer S.J. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74 (1993) 609-619
52. Gillardon F., Lenz C., Waschke K.F., Krajewski S., Reed J.C., Zimmermann M., et al. Altered expression of Bcl-2, Bcl-X, Bax, and c-Fos colocalizes with DNA fragmentation and ischemic cell damage following middle cerebral artery occlusion in rats. Brain Res Mol Brain Res 40 (1996) 254-260
53. Yin X.M., Oltvai Z.N., and Korsmeyer S.J. BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax. Nature 369 (1994) 321-323
54. Hinz B., Gabbiani G., and Chaponnier C. The NH2-terminal peptide of alpha-smooth muscle actin inhibits force generation by the myofibroblast in vitro and in vivo. J Cell Biol 157 (2002) 657-663
55. Serini G., Bochaton-Piallat M.L., Ropraz P., Geinoz A., Borsi L., Zardi L., et al. The fibronectin domain ED-A is crucial for myofibroblastic phenotype induction by transforming growth factor-beta1. J Cell Biol 142 (1998) 873-81