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Volumn 447, Issue 2-3, 2008, Pages 172-174

Focal distortion of the nuclear envelope by huntingtin aggregates revealed by lamin immunostaining

Author keywords

Aggregation; Huntingtin; Lamin; Nuclear envelope; Polyglutamine

Indexed keywords

ATAXIN 1; DNA; HUNTINGTIN; LAMIN B; POLYGLUTAMINE;

EID: 55049100926     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2008.09.075     Document Type: Article
Times cited : (14)

References (25)
  • 1
    • 0242531029 scopus 로고    scopus 로고
    • Inhibition of proteasomal activity causes inclusion formation in neuronal and non-neuronal cells overexpressing Parkin
    • Ardley H.C., Scott G.B., Rose S.A., Tan N.G., Markham A.F., and Robinson P.A. Inhibition of proteasomal activity causes inclusion formation in neuronal and non-neuronal cells overexpressing Parkin. Mol. Biol. Cell 14 (2003) 4541-4556
    • (2003) Mol. Biol. Cell , vol.14 , pp. 4541-4556
    • Ardley, H.C.1    Scott, G.B.2    Rose, S.A.3    Tan, N.G.4    Markham, A.F.5    Robinson, P.A.6
  • 2
    • 7244236320 scopus 로고    scopus 로고
    • Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death
    • Arrasate M., Mitra S., Schweitzer E.S., Segal M.R., and Finkbeiner S. Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death. Nature 431 (2004) 805-810
    • (2004) Nature , vol.431 , pp. 805-810
    • Arrasate, M.1    Mitra, S.2    Schweitzer, E.S.3    Segal, M.R.4    Finkbeiner, S.5
  • 4
    • 14644419638 scopus 로고    scopus 로고
    • Neuronal dysfunction in a polyglutamine disease model occurs in the absence of ubiquitin-proteasome system impairment and inversely correlates with the degree of nuclear inclusion formation
    • Bowman A.B., Yoo S.Y., Dantuma N.P., and Zoghbi H.Y. Neuronal dysfunction in a polyglutamine disease model occurs in the absence of ubiquitin-proteasome system impairment and inversely correlates with the degree of nuclear inclusion formation. Hum. Mol. Genet. 14 (2005) 679-691
    • (2005) Hum. Mol. Genet. , vol.14 , pp. 679-691
    • Bowman, A.B.1    Yoo, S.Y.2    Dantuma, N.P.3    Zoghbi, H.Y.4
  • 5
    • 0031985869 scopus 로고    scopus 로고
    • Truncated forms of the androgen receptor are associated with polyglutamine expansion in X-linked spinal and bulbar muscular atrophy
    • Butler R., Leigh P.N., McPhaul M.J., and Gallo J.-M. Truncated forms of the androgen receptor are associated with polyglutamine expansion in X-linked spinal and bulbar muscular atrophy. Hum. Mol. Genet. 7 (1998) 121-127
    • (1998) Hum. Mol. Genet. , vol.7 , pp. 121-127
    • Butler, R.1    Leigh, P.N.2    McPhaul, M.J.3    Gallo, J.-M.4
  • 7
    • 0033391428 scopus 로고    scopus 로고
    • Mutation of the E6-AP ubiquitin ligase reduces nuclear inclusion frequency while accelerating polyglutamine-induced pathology in SCA1 mice
    • Cummings C.J., Reinstein E., Sun Y., Antalffy B., Jiang Y., Ciechanover A., Orr H.T., Beaudet A.L., and Zoghbi H.Y. Mutation of the E6-AP ubiquitin ligase reduces nuclear inclusion frequency while accelerating polyglutamine-induced pathology in SCA1 mice. Neuron 24 (1999) 879-892
    • (1999) Neuron , vol.24 , pp. 879-892
    • Cummings, C.J.1    Reinstein, E.2    Sun, Y.3    Antalffy, B.4    Jiang, Y.5    Ciechanover, A.6    Orr, H.T.7    Beaudet, A.L.8    Zoghbi, H.Y.9
  • 8
    • 32044433784 scopus 로고    scopus 로고
    • The role of the nuclear envelope in cellular organization
    • D'Angelo M.A., and Hetzer M.W. The role of the nuclear envelope in cellular organization. Cell Mol. Life Sci. 63 (2006) 316-332
    • (2006) Cell Mol. Life Sci. , vol.63 , pp. 316-332
    • D'Angelo, M.A.1    Hetzer, M.W.2
  • 11
    • 25844487226 scopus 로고    scopus 로고
    • Diseases of unstable repeat expansion: mechanisms and common principles
    • Gatchel J.R., and Zoghbi H.Y. Diseases of unstable repeat expansion: mechanisms and common principles. Nat. Rev. Genet. 6 (2005) 743-755
    • (2005) Nat. Rev. Genet. , vol.6 , pp. 743-755
    • Gatchel, J.R.1    Zoghbi, H.Y.2
  • 12
    • 37349007785 scopus 로고    scopus 로고
    • Time-lapse analysis of aggregate formation in an inducible PC12 cell model of Huntington's disease reveals time-dependent aggregate formation that transiently delays cell death
    • Gong B., Lim M.C., Wanderer J., Wyttenbach A., and Morton A.J. Time-lapse analysis of aggregate formation in an inducible PC12 cell model of Huntington's disease reveals time-dependent aggregate formation that transiently delays cell death. Brain Res. Bull. 75 (2008) 146-157
    • (2008) Brain Res. Bull. , vol.75 , pp. 146-157
    • Gong, B.1    Lim, M.C.2    Wanderer, J.3    Wyttenbach, A.4    Morton, A.J.5
  • 17
    • 34547692622 scopus 로고    scopus 로고
    • Trinucleotide repeat disorders
    • Orr H.T., and Zoghbi H.Y. Trinucleotide repeat disorders. Annu. Rev. Neurosci. 30 (2007) 575-621
    • (2007) Annu. Rev. Neurosci. , vol.30 , pp. 575-621
    • Orr, H.T.1    Zoghbi, H.Y.2
  • 18
    • 0037099080 scopus 로고    scopus 로고
    • The cellular fate of mutant rhodopsin: quality control, degradation and aggresome formation
    • Saliba R.S., Munro P.M., Luthert P.J., and Cheetham M.E. The cellular fate of mutant rhodopsin: quality control, degradation and aggresome formation. J. Cell Sci. 115 (2002) 2907-2918
    • (2002) J. Cell Sci. , vol.115 , pp. 2907-2918
    • Saliba, R.S.1    Munro, P.M.2    Luthert, P.J.3    Cheetham, M.E.4
  • 19
    • 0037684765 scopus 로고    scopus 로고
    • The nucleoskeleton: lamins and actin are major players in essential nuclear functions
    • Shumaker D.K., Kuczmarski E.R., and Goldman R.D. The nucleoskeleton: lamins and actin are major players in essential nuclear functions. Curr. Opin. Cell Biol. 15 (2003) 358-366
    • (2003) Curr. Opin. Cell Biol. , vol.15 , pp. 358-366
    • Shumaker, D.K.1    Kuczmarski, E.R.2    Goldman, R.D.3
  • 21
    • 1042266326 scopus 로고    scopus 로고
    • Aggresomes formed by alpha-synuclein and synphilin-1 are cytoprotective
    • Tanaka M., Kim Y.M., Lee G., Junn E., Iwatsubo T., and Mouradian M.M. Aggresomes formed by alpha-synuclein and synphilin-1 are cytoprotective. J. Biol. Chem. 279 (2004) 4625-4631
    • (2004) J. Biol. Chem. , vol.279 , pp. 4625-4631
    • Tanaka, M.1    Kim, Y.M.2    Lee, G.3    Junn, E.4    Iwatsubo, T.5    Mouradian, M.M.6
  • 23
    • 0034754875 scopus 로고    scopus 로고
    • Accumulation of mutant huntingtin fragments in aggresome-like inclusion bodies as a result of insufficient protein degradation
    • Waelter S., Boeddrich A., Lurz R., Scherzinger E., Lueder G., Lehrach H., and Wanker E.E. Accumulation of mutant huntingtin fragments in aggresome-like inclusion bodies as a result of insufficient protein degradation. Mol. Biol. Cell 12 (2001) 1393-1407
    • (2001) Mol. Biol. Cell , vol.12 , pp. 1393-1407
    • Waelter, S.1    Boeddrich, A.2    Lurz, R.3    Scherzinger, E.4    Lueder, G.5    Lehrach, H.6    Wanker, E.E.7
  • 24
    • 2442624755 scopus 로고    scopus 로고
    • Microtubule disruption inhibits autophagosome-lysosome fusion: implications for studying the roles of aggresomes in polyglutamine diseases
    • Webb J.L., Ravikumar B., and Rubinsztein D.C. Microtubule disruption inhibits autophagosome-lysosome fusion: implications for studying the roles of aggresomes in polyglutamine diseases. Int. J. Biochem. Cell Biol. 36 (2004) 2541-2550
    • (2004) Int. J. Biochem. Cell Biol. , vol.36 , pp. 2541-2550
    • Webb, J.L.1    Ravikumar, B.2    Rubinsztein, D.C.3
  • 25
    • 0036566675 scopus 로고    scopus 로고
    • Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntingtin
    • Wyttenbach A., Sauvageot O., Carmichael J., Diaz-Latoud C., Arrigo A.P., and Rubinsztein D.C. Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntingtin. Hum. Mol. Genet. 11 (2002) 1137-1151
    • (2002) Hum. Mol. Genet. , vol.11 , pp. 1137-1151
    • Wyttenbach, A.1    Sauvageot, O.2    Carmichael, J.3    Diaz-Latoud, C.4    Arrigo, A.P.5    Rubinsztein, D.C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.