Corneal In Vivo Confocal Scanning Laser Microscopy in Patients with Atopic Keratoconjunctivitis

Ophthalmology

Volumn 115, Issue 11, 2008, Pages 2004-2012

  Hu, Yiqian ^a,b   Matsumoto, Yukihiro ^a   Adan, Enrique Sato ^a   Dogru, Murat ^a,c   Fukagawa, Kazumi ^a   Tsubota, Kazuo ^a   Fujishima, Hiroshi ^a,d  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

^c TOKYO DENTAL COLLEGE   (Japan)

^d International University of Health and Welfare Mita Hospital   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ROSE BENGAL;

ADOLESCENT; ADULT; ARTICLE; ATOPIC KERATOCONJUNCTIVITIS; CLINICAL ARTICLE; CLINICAL FEATURE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CORNEA ENDOTHELIUM; CORNEA EPITHELIUM; EYE EXAMINATION; FEMALE; FLUORESCENCE ANALYSIS; HUMAN; IN VIVO STUDY; LABORATORY TEST; MALE; MORPHOLOGY; NERVE FIBER; PRIORITY JOURNAL; PROSPECTIVE STUDY; SCHOOL CHILD; SLIT LAMP;

ADOLESCENT; ADULT; CELL COUNT; CHILD; CONJUNCTIVITIS, ALLERGIC; CORNEA; FEMALE; FLUORESCEIN; FLUORESCENT DYES; HUMANS; MALE; MICROSCOPY, CONFOCAL; OPHTHALMIC NERVE; PROSPECTIVE STUDIES; ROSE BENGAL; STAINING AND LABELING; TEARS; YOUNG ADULT;

EID: 54949115476     PISSN: 01616420     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ophtha.2008.05.010     Document Type: Article

References (38)

1. Mortz C.G., Lauritsen J.M., Bindslev-Jensen C., and Andersen K.E. Prevalence of atopic dermatitis, asthma, allergic rhinitis, and hand and contact dermatitis in adolescents: the Odense Adolescence Cohort Study on Atopic Diseases and Dermatitis. Br J Dermatol 144 (2001) 523-532
2. Bacon A.S., Tuft S.J., Metz D.M., et al. The origin of keratopathy in chronic allergic eye disease: a histopathological study. Eye 7 suppl (1993) 21-25
3. Dogru M., Okada N., Asano-Kato N., et al. Atopic ocular surface disease: implications on tear function and ocular surface mucins. Cornea 24 suppl (2005) S18-S23
4. Dogru M., Yildiz M., Baykara M., et al. Corneal sensitivity and ocular surface changes following preserved amniotic membrane transplantation for nonhealing corneal ulcers. Eye 17 (2003) 139-148
5. Junko H. AD classification of fluorescein staining. In: Tano Y., and Watanabe N. (Eds). Practical Ophthalmology (1998), Bunkodo Co, Ltd, Tokyo 61 [in Japanese]
6. Toda I., and Tsubota K. Practical double vital staining for ocular surface evaluation. [letter]. Cornea 12 (1993) 366-367
7. Leibowitz H.M., and Villazon S. Corneal procedures. In: Leibowitz H.M., and Waring III G.O. (Eds). Corneal Disorders: Clinical Diagnosis and Management. 2nd ed. (1998), Saunders, Philadelphia 983-984
8. Mocan M.C., Durukan I., Irkec M., and Orhan M. Morphologic alterations of both the stromal and subbasal nerves in the corneas of patients with diabetes. Cornea 25 (2006) 769-773
9. Guthoff R.F., and Stave J. In vivo micromorphology of the cornea: confocal microscopy principles and clinical applications. In: Reinhard T., and Larkin D.F.P. (Eds). Cornea and External Eye Disease (2006), Springer, Berlin 173-208 In: Krieglstein GK, Weinreb RN, series eds. Essentials in Ophthalmology.
10. Benitez del Castillo J.M., Wasfy M.A., Fernadez C., and Garcia-Sanchez J. An in vivo confocal masked study on corneal epithelium and subbasal nerves in patients with dry eye. Invest Ophthalmol Vis Sci 45 (2004) 3030-3035
11. Rosenberg M.E., Tervo T.M., Immonen I.J., et al. Corneal structure and sensitivity in type 1 diabetes mellitus. Invest Ophthalmol Vis Sci 41 (2000) 2915-2921
12. Pfister D.R., Cameron J.D., Krachmer J.H., and Holland E.J. Confocal microscopy findings of Acanthamoeba keratitis. Am J Ophthalmol 121 (1996) 119-128
13. Labbe A., Dupas B., Bensoussan L., and Baudouin C. Bilateral infectious ulcers associated with atopic keratoconjunctivitis. Cornea 25 (2006) 248-250
14. Rosenberg M.E., Tervo T.M., Muller L.J., et al. In vivo confocal microscopy after herpes keratitis. Cornea 21 (2002) 265-269
15. Patel D.V., and McGhee C.N. Mapping the corneal sub-basal nerve plexus in keratoconus by in vivo laser scanning confocal microscopy. Invest Ophthalmol Vis Sci 47 (2006) 1348-1351
16. Erie J.C., McLaren J.W., Hodge D.O., and Bourne W.M. The effect of age on the corneal subbasal nerve plexus. Cornea 24 (2005) 705-709
17. Patel S.V., McLaren J.W., Hodge D.O., and Bourne W.M. Confocal microscopy in vivo in corneas of long-term contact lens wearers. Invest Ophthalmol Vis Sci 43 (2002) 995-1003
18. Sonigo B., Iordanidou V., Chong-Sit D., et al. In vivo corneal confocal microscopy comparison of intraLase femtosecond laser and mechanical microkeratome for laser in situ keratomileusis. Invest Ophthalmol Vis Sci 47 (2006) 2803-2811
19. Muller L.J., Marfurt C.F., Kruse F., and Tervo T.M. Corneal nerves: structure, contents and function. Exp Eye Res 76 (2003) 521-542
20. Gabison E.E., Alfonsi N., Doan S., et al. Archipelago keratitis: a clinical variant of recurrent herpetic keratitis?. Ophthalmology 114 (2007) 2000-2005
21. Efron N., and Hollingsworth J.G. New perspectives on keratoconus as revealed by corneal confocal microscopy. Clin Exp Optom 91 (2008) 34-55
22. Onguchi T., Dogru M., Okada N., et al. The impact of the onset time of atopic keratoconjunctivitis on the tear function and ocular surface findings. Am J Ophthalmol 141 (2006) 569-571
23. Benítez-Del-Castillo J.M., Acosta M.C., Wassfi M.A., et al. Relation between corneal innervation with confocal microscopy and corneal sensitivity with noncontact esthesiometry in patients with dry eye. Invest Ophthalmol Vis Sci 48 (2007) 173-181
24. Villani E., Galimberti D., Viola F., et al. The cornea in Sjogren's syndrome: an in vivo confocal study. Invest Ophthalmol Vis Sci 48 (2007) 2017-2022
25. Zhang M., Chen J., Luo L., et al. Altered corneal nerves in aqueous tear deficiency viewed by in vivo confocal microscopy. Cornea 24 (2005) 818-824
26. Erdelyi B., Kraak R., Zhivov A., et al. In vivo confocal laser scanning microscopy of the cornea in dry eye. Graefes Arch Clin Exp Ophthalmol 245 (2007) 39-44
27. Kallinikos P., Berhanu M., O'Donnell C., et al. Corneal nerve tortuosity in diabetic patients with neuropathy. Invest Ophthalmol Vis Sci 45 (2004) 418-422
28. Guthoff R.F., Wienss H., Hahnel C., and Wree A. Epithelial innervation of human cornea: a three-dimensional study using confocal laser scanning fluorescence microscopy. Cornea 24 (2005) 608-613
29. Garcia-Hirschfeld J., Lopez-Briones L.G., and Belmonte C. Neurotrophic influences on corneal epithelial cells. Exp Eye Res 59 (1994) 597-605
30. Quadrado M.J., Popper M., Morgado A.M., et al. Diabetes and corneal cell densities in humans by in vivo confocal microscopy. Cornea 25 (2006) 761-768
31. Reid T.W., Murphy C.J., Iwahashi C.K., et al. Stimulation of epithelial cell growth by the neuropeptide substance P. J Cell Biochem 52 (1993) 476-485
32. Lambiase A., Manni L., Bonini S., et al. Nerve growth factor promotes corneal healing: structural, biochemical, and molecular analyses of rat and human corneas. Invest Ophthalmol Vis Sci 41 (2000) 1063-1069
33. Dogru M., Okada N., Asano-Kato N., et al. Alterations of the ocular surface epithelial mucins 1, 2, 4 and the tear functions in patients with atopic keratoconjunctivitis. Clin Exp Allergy 36 (2006) 1556-1565
34. Uchio E., Ono S.Y., Ikezawa Z., and Ohno S. Tear levels of interferon-gamma, interleukin (IL)-2,IL-4 and IL-5 in patients with vernal keratoconjunctivitis, atopic keratoconjunctivitis and allergic conjunctivitis. Clin Exp Allergy 30 (2000) 103-109
35. Jester J.V., Petroll W.M., and Cavanagh H.D. Corneal stromal wound healing in refractive surgery: the role of myofibroblasts. Prog Retin Eye Res 18 (1999) 311-356
36. Tuominen I.S.J., Konttinen Y.T., Vesaluoma M.H., et al. Corneal innervation and morphology in primary Sjogren's syndrome. Invest Ophthalmol Vis Sci 44 (2003) 2545-2549
37. Albers K.M., Wright D.E., and Davis B.M. Overexpression of nerve growth factor in epidermis of transgenic mice causes hypertrophy of the peripheral nervous system. J Neurosci 14 (1994) 1422-1432
38. Dogru M., Asano-Kato N., Tanaka M., et al. Ocular surface and MUC5AC alterations in atopic patients with corneal shield ulcers. Cur Eye Res 30 (2005) 897-908