Natural autoantibodies reactive with glycosaminoglycans in rheumatoid arthritis

Arthritis Research and Therapy

Volumn 10, Issue 5, 2008, Pages

  György, Bence ^a   Tóthfalusi, László ^a   Nagy, György ^a   Pásztói, Mária ^a   Géher, Pál ^a   Lörinc, Zsolt ^b   Polgár, Anna ^c   Rojkovich, Bernadett ^a   Ujfalussy, Ilona ^a   Poór, Gyula ^c   Pócza, Péter ^a   Wiener, Zoltán ^a   Misják, Petra ^a   Koncz, Agnes ^d   Falus, András ^a,b   Buzás, Edit I ^a  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^c NATIONAL INSTITUTE OF RHEUMATOLOGY AND PHYSIOTHERAPY   (Hungary)

^d Pal Heim Children's Hospital   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; AUTOANTIGEN; BIOLOGICAL MARKER; C REACTIVE PROTEIN; GLYCOSAMINOGLYCAN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; RHEUMATOID FACTOR;

ADULT; AGED; ARTICLE; BLOOD; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; MALE; MIDDLE AGED; RHEUMATOID ARTHRITIS; SYNOVIAL FLUID;

ADULT; AGED; ARTHRITIS, RHEUMATOID; AUTOANTIBODIES; AUTOANTIGENS; BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GLYCOSAMINOGLYCANS; HUMANS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; RHEUMATOID FACTOR; SYNOVIAL FLUID;

EID: 54749117031     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar2507     Document Type: Article

References (41)

1. Lee DM Weinblatt ME Rheumatoid arthritis Lancet 2001, 358:903-911. 10.1016/S0140-6736(01)06075-5 11567728
2. Blass S Engel JM Burmester GR The immunologic homunculus in rheumatoid arthritis. A new viewpoint of immunopathogenesis in rheumatoid arthritis and therapeutic consequences Z Rheumatol 2001, 60:1-16. 10.1007/ s003930170093 11263010
3. Robinson WH DiGennaro C Hueber W Haab BB Kamachi M Dean EJ Fournel S Fong D Genovese MC de Vegvar HE Skriner K Hirschberg DL Morris RI Muller S Pruijn GJ van Venrooij WJ Smolen JS Brown PO Steinman L Utz PJ Autoantigen microarrays for multiplex characterization of autoantibody responses Nat Med 2002, 8:295-301. 10.1038/nm0302-295 11875502
4. van Gaalen FA Linn-Rasker SP van Venrooij WJ de Jong BA Breedveld FC Verweij CL Toes RE Huizinga TW Autoantibodies to cyclic citrullinated peptides predict progression to rheumatoid arthritis in patients with undifferentiated arthritis: A prospective cohort study Arthritis Rheum 2004, 50:709-715. 10.1002/art.20044 15022309
5. Visser H le Cessie S Vos K Breedveld FC Hazes JM How to diagnose rheumatoid arthritis early: A prediction model for persistent (erosive) arthritis Arthritis Rheum 2002, 46:357-365. 10.1002/art.10117 11840437
6. Verpoort KN Jol-van der Zijde CM Papendrecht-van der Voort EA Ioan-Facsinay A Drijfhout JW van Tol MJ Breedveld FC Huizinga TW Toes RE Isotype distribution of anti-cyclic citrullinated peptide antibodies in undifferentiated arthritis and rheumatoid arthritis reflects an ongoing immune response Arthritis Rheum 2006, 54:3799-3808. 10.1002/art.22279 17133560
7. Dorner T Egerer K Feist E Burmester GR Rheumatoid factor revisited Curr Opin Rheumatol 2004, 16:246-253. 10.1097/00002281-200405000-00013 15103252
8. Cohen IR Biomarkers, self-antigens and the immunological homunculus J Autoimmun 2007, 29:246-249. 10.1016/j.jaut.2007.07.016 17888625
9. Glant TT Mikecz K Arzoumanian A Poole AR Proteoglycan-induced arthritis in BALB/c mice. Clinical features and histopathology Arthritis Rheum 1987, 30:201-212. 10.1002/art.1780300211 3827960
10. Glant TT Buzas EI Finnegan A Negroiu G Cs-Szabo G Mikecz K Critical roles of glycosaminoglycan side chains of cartilage proteoglycan (aggrecan) in antigen recognition and presentation J Immunol 1998, 160:3812-3819. 9558085
11. Polgar A Falus A Koo E Ujfalussy I Sesztak M Szuts I Konrad K Hodinka L Bene E Meszaros G Ortutay Z Farkas E Paksy A Buzas EI Elevated levels of synovial fluid antibodies reactive with the small proteoglycans biglycan and decorin in patients with rheumatoid arthritis or other joint diseases Rheumatology (Oxford) 2003, 42:522-527. 10.1093/rheumatology/ keg168 12649398
12. Arnett FC Edworthy SM Bloch DA McShane DJ Fries JF Cooper NS Healey LA Kaplan SR Liang MH Luthra HS Medsger TA Mitchell DM Neustadt DH Pinals RS Schaller JG Sharp JT Wilder RL Hunder GG The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis Arthritis Rheum 1988, 31:315-324. 10.1002/art.1780310302 3358796
13. Disease activity score in rheumatoid arthritis http://www.das-score.nl/ www.das-score.nl/index.html
14. Zielen S Broker M Strnad N Schwenen L Schon P Gottwald G Hofmann D Simple determination of polysaccharide specific antibodies by means of chemically modified ELISA plates J Immunol Methods 1996, 193:1-7. 10.1016/0022-1759(96)00033-6 8690926
15. Glant TT Mikecz K Poole AR Monoclonal antibodies to different protein-related epitopes of human articular cartilage proteoglycans Biochem J 1986, 234:31-41. 1146523 2423072
16. Harell JR Frank E Regression modeling strategies: With applications to linear models, logistic regression, and survival analysis New York: Springer 2001.
17. Venables WN Ripley BD Modern Applied Statistics with S-PLUS New York: Springer 1999.
18. Koga M Matsuoka T Katayama K Takeda K Nakata M Sase M Kato H Furukawa S Human parvovirus B19 in cord blood of premature infants Am J Perinatol 2001, 18:237-240. 10.1055/s-2001-16988 11552176
19. Inoue E Yamanaka H Hara M Tomatsu T Kamatani N Comparison of Disease Activity Score (DAS)28- erythrocyte sedimentation rate and DAS28- C-reactive protein threshold values Ann Rheum Dis 2007, 66:407-409. 10.1136/ard.2006.054205 16926186
20. Prevoo ML van't Hof MA Kuper HH van Leeuwen MA Putte van de LB van Riel PL Modified disease activity scores that include twenty-eight joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis Arthritis Rheum 1995, 38:44-48. 10.1002/art.1780380107 7818570
21. Morozzi G Fabbroni M Bellisai F Cucini S Simpatico A Galeazzi M Low serum level of COMP, a cartilage turnover marker, predicts rapid and high ACR70 response to adalimumab therapy in rheumatoid arthritis Clin Rheumatol 2007, 26:1335-1338. 10.1007/s10067-006-0520-y 17285224
22. Ortutay Z Polgár A Gömör B Géher P Lakatos T Glant TT Gay RE Gay S Pállinger E Farkas C Farkas E Tóthfalusi L Kocsis K Falus A Buzás EI Synovial fluid exoglycosidases are predictors of rheumatoid arthritis and are effective in cartilage glycosaminoglycan depletion Arthritis Rheum 2003, 48:2163-2172. 10.1002/art.11093 12905469
23. Edwards JC Szczepanski L Szechinski J Filipowicz-Sosnowska A Emery P Close DR Stevens RM Shaw T Efficacy of B-cell-targeted therapy with rituximab in patients with rheumatoid arthritis N Engl J Med 2004, 350:2572-2581. 10.1056/NEJMoa032534 15201414
24. Landsteiner K Über Agglutinationserscheinungen normalen menschlichen Blutes. Wien Klin Wochenschr 1901; 14: 1132-1134 (Translation: On agglutination phenomena of normal human blood) Papers on Human Genetics Englewood Cliffs, NJ: Prentice-Hall Boyer SH 1963, 1132-1134.
25. Adderson EE Shikhman AR Ward KE Cunningham MW Molecular analysis of polyreactive monoclonal antibodies from rheumatic carditis: Human anti-N-acetylglucosamine/anti-myosin antibody V region genes J Immunol 1998, 161:2020-2031. 9712075
26. Majeed M McQueen F Yeoman S McLean L Relationship between serum hyaluronic acid level and disease activity in early rheumatoid arthritis Ann Rheum Dis 2004, 63:1166-1168. 1755107 15308530 10.1136/ ard.2003.010942
27. Pothacharoen P Teekachunhatean S Louthrenoo W Yingsung W Ong-Chai S Hardingham T Kongtawelert P Raised chondroitin sulfate epitopes and hyaluronan in serum from rheumatoid arthritis and osteoarthritis patients Osteoarthritis Cartilage 2006, 14:299-301. 10.1016/ j.joca.2005.10.005 16309927
28. Landers CD Chelvarajan RL Bondada S The role of B-cells and accessory cells in the neonatal response to TI-2 antigens Immunol Res 2005, 31:25-36. 10.1385/IR:31:1:25 15591620
29. Zandvoort A Timens W The dual function of the splenic marginal zone: essential for initiation of anti-TI-2 responses but also vital in the general first-line defense against blood-borne antigens Clin Exp Immunol 2002, 130:4-11. 1906503 12296846 10.1046/j.1365-2249.2002.01953.x
30. Adderson EE Antibody repertoires in infants and adults: Effects of T-independent and T-dependent immunizations Springer Semin Immunopathol 2001, 23:387-403. 10.1007/s281-001-8166-x 11826616
31. Rijkers GT Sanders EA Breukels MA Zegers BJ Infant B-cell responses to polysaccharide determinants Vaccine 1998, 16:1396-1400. 10.1016/ S0264-410X(98)00098-X 9711778
32. Wang JY Roehrl MH Glycosaminoglycans are a potential cause of rheumatoid arthritis Proc Natl Acad Sci USA 2002, 99:14362-14367. 137889 12391302 10.1073/pnas.222536599
33. Nakiri Y Minowa K Suzuki J Mitsuo A Amano H Morimoto S Tokano Y Takasaki Y Expression of CD22 on peripheral B-cells in patients with rheumatoid arthritis: Relation to CD5-positive B-cells Clin Rheumatol 2007, 26:1721-1723. 10.1007/s10067-007-0665-3 17585360
34. Montecino-Rodriguez E Dorshkind K New perspectives in B-1 B-cell development and function Trends Immunol 2006, 27:428-433. 10.1016/ j.it.2006.07.005 16861037
35. Parisi JT Significance of chromogenic variants in studies of virulence factors of Staphylococcus aureus J Bacteriol 1966, 92:589-591. 276294 5922534 10.1002/path.1700920243
36. Starr CR Engleberg NC Role of hyaluronidase in subcutaneous spread and growth of group A streptococcus Infect Immun 2006, 74:40-48. 1346594 16368955 10.1128/IAI.74.1.40-48.2006
37. Shimizu T Ohtani K Hirakawa H Ohshima K Yamashita A Shiba T Ogasawara N Hattori M Kuhara S Hayashi H Complete genome sequence of Clostridium perfringens, an anaerobic flesh-eater Proc Natl Acad Sci USA 2002, 99:996-1001. 117419 11792842 10.1073/pnas.022493799
38. Matthews BW The structure of E. coli beta-galactosidase C R Biol 2005, 328:549-556. 10.1016/j.crvi.2005.03.006 15950161
39. Buzas EI Gyorgy B Pasztoi M Jelinek I Falus A Gabius HJ Carbohydrate recognition systems in autoimmunity Autoimmunity 2006, 39:691-704. 10.1080/08916930601061470 17178566
40. Black S Shinefield H Eskola J Whitney C Pneumococcal Conjugate Vaccines Vaccines Philadelphia: Elsevier Plotkin S, Orenstein W, Offit P 5, 2008.
41. Poletaev A Osipenko L General network of natural autoantibodies as immunological homunculus (Immunculus) Autoimmun Rev 2003, 2:264-271. 10.1016/S1568-9972(03)00033-8 12965177