The role of B cells and accessory cells in the neonatal response to TI-2 antigens

Immunologic Research

Volumn 31, Issue 1, 2005, Pages 25-36

  Landers, Cheri D ^a   Chelvarajan, R Lakshman ^a   Bondada, Subbarao ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Accessory cell; B cell; Cytokines; Macrophage; Neonate; Polysaccharide; Thymus independent

Indexed keywords

CELL MARKER; THYMOCYTE ANTIBODY;

ACCESSORY CELL; ANIMAL CELL; ANIMAL TISSUE; ANTIBODY PRODUCTION; ANTIGEN DETECTION; B LYMPHOCYTE; CELL COMPOSITION; CELL SURFACE; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENETIC SUSCEPTIBILITY; HUMAN; IMMUNOLOGICAL TOLERANCE; INFECTION SENSITIVITY; MOUSE; NEWBORN; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REVIEW; RISK FACTOR; SPLEEN CELL;

ANTIGEN-PRESENTING CELLS; ANTIGENS, T-INDEPENDENT; B-LYMPHOCYTES; HUMANS; INFANT, NEWBORN; SPLEEN;

EID: 11244309062     PISSN: 0257277X     EISSN: None     Source Type: Journal    
DOI: 10.1385/IR:31:1:25     Document Type: Review

References (65)

1. Adderson EE: Antibody repertoires in infants and adults: effects of T-independent and T-dependent immunizations. Springer Semin Immunopathol 2001;23: 387-403.
2. Pabst HF, Kreth HW: Ontogeny of the immune response as a basis of childhood disease. J Pediatr 1980;97:519-534.
3. Bondada S, Garg M: Thymus-independent antigens. In: Snow EC. (ed.), Handbook of B and T Lymphocytes. Academic Press, Inc., San Diego, 1994, pp. 343-370.
4. Mond JJ, Lees A, Snapper CM: T cell-independent antigens type 2. Annu Rev Immunol 1995;13:655-692.
5. Snapper CM, Mond JJ: A model for induction of T cell-independent humoral immunity in response to polysaccharide antigens. J Immunol 1996;157:2229-2233.
6. Snapper CM, Rosas FR, Moorman MA, Mond JJ: Restoration of T cell-independent type 2 induction of Ig secretion by neonatal B cells in vitro. J Immunol 1997;158:2731-2735.
7. Ambrosino DM, Delaney NR, Shamberger RC: Human polysaccharide-specific B cells are responsive to pokeweed mitogen and IL-6. J Immunol 1990;144: 1221-1226.
8. Chelvarajan RL, Gilbert NL, Bondada S: Neonatal murine B lymphocytes respond to polysaccharide antigens in the presence of IL-1 and IL-6. J Immunol 1998;161:3315-3324.
9. Broome CV, Breiman RF: Pneumococcal vaccine-past present and future. N Engl J Med 1991;325:1506-1508.
10. Rennels MB, Edwards KM, Keyserling HL, Reisinger KS, Hogerman DA, Madore DV, et al.: Safety and immunogenicity of heptavalent pneumococcal vaccine conjugated to CRM197 in United States infants. Pediatrics 1998;101:604-611.
11. Nossal GJ: Cellular mechanisms of immunologic tolerance. Annu Rev Immunol 1983;1:33-62.
12. Baker PJ: T cell regulation of the antibody response to bacterial polysaccharide antigens: an examination of some general characteristics and their implications. J Infect Dis 1992;165:S44-48.
13. Mosier DE, Zitron IM, Mond JJ, Ahmed A, Scher I, Paul WE: Surface immunoglobulin D as a functional receptor for a subclass of B lymphocytes. Immunol Rev 1977;37:89-104.
14. Scher I, Berning AK, Kessler S, Finkelman FD: Development of B lymphocytes in the mouse; studies of the frequency and distribution of surface IgM and IgD in normal and immune-defective CBA/N F1 mice. J Immunol 1980;125:1686-1693.
15. Carsetti R, Kohler G, Lamers MC: Transitional B cells are the target of negative selection in the B cell compartment. J Exp Med 1995;181:2129-2140.
16. Gathings WE, Kubagawa H, Cooper MD: A distinctive pattern of B cell immaturity in perinatal humans. Immunol Rev 1981;57:107-126.
17. Griffioen AW, Franklin SW, Zegers BJ, Rijkers GT: Expression and functional characteristics of the complement receptor type 2 on adult and neonatal B lymphocytes. Clin Immunol Immunopathol 1993;69:1-8.
18. Griffioen AW, Toebes EA, Zegers BJ, Rijkers GT: Role of CR2 in the human adult and neonatal in vitro antibody response to type 4 pneumococcal polysaccharide. Cell Immunol 1992;143:11-22.
19. Hamilton AM, Lehuen A, Kearney JF: Immunofluorescence analysis of B-1 cell ontogeny in the mouse. Int Immunol 1994;6:355-361.
20. Bofill M, Janossy G, Janossa M, Burford GD, Seymour GJ, Wernet P, Kelemen E: Human B cell development. II. Subpopulations in the human fetus. J Immunol 1985;134:1531-1538.
21. Barrett DJ, Sleasman JW, Schatz DA, Steinitz M: Human anti- pneumococcal polysaccharide antibodies are secreted by the CD5- B cell lineage. Cell Immunol 1992;143:66-79.
22. Brooks DA, Beckman IG, Bradley J, McNamara PJ, Thomas ME, Zola H: Human lymphocyte markers defined by antibodies derived from somatic cell hybrids. IV. A monoclonal antibody reacting specifically with a subpopulation of human B lymphocytes. J Immunol 1981;126:1373-1377.
23. Rijkers GT, Dollekamp EG, Zegers BJ: The in vitro B-cell response to pneumococcal polysaccharides in adults and neonates. Scand J Immunol 1987;25:447-452.
24. Bloem AC, Chand MA, Dollekamp I, Rijkers GT: Functional properties of human B cell subpopulations defined by monoclonal antibodies HB4 and FMC7. J Immunol 1988;140:768-773.
25. Saito S, Morii T, Umekage H, Makita K, Nishikawa K, Narita N, et al.: Expression of the interleukin-2 receptor gamma chain on cord blood mononuclear cells. Blood 1996;87:3344-3350.
26. Zola H, Fusco M, Macardle PJ, Flego L, Roberton D: Expression of cytokine receptors by human cord blood lymphocytes: comparison with adult blood lymphocytes. Pediatr Res 1995;38:397-403.
27. Zola H, Fusco M, Weedon H, Macardle PJ, Ridings J, Roberton DM: Reduced expression of the interleukin-2-receptor gamma chain on cord blood lymphocytes: relationship to functional immaturity of the neonatal immune response. Immunology 1996;87:86-91.
28. Rijkers GT, Dollekamp I, Zegers BJ: 8-Mercaptoguanosine overcomes unresponsiveness of human neonatal B cells to polysaccharide antigens. J Immunol 1988;141: 2313-2316.
29. Bohnsack JF, Brown EJ: The role of the spleen in resistance to infection. Annu Rev Med 1986;37:49-59.
30. Goud SN, Muthusamy N, Subbarao B: Differential responses of B cells from the spleen and lymph node to TNP-Ficoll. J Immunol 1988;140:2925-2930.
31. Humphrey JH, Grennan D: Different macrophage populations distinguished by means of fluorescent polysaccharides. Recognition and properties of marginal-zone macrophages. Eur J Immunol 1981;11:221-228.
32. Kraal G, Ter Hart H, Meelhuizen C, Venneker G, Claassen E: Marginal zone macrophages and their role in the immune response against T-independent type 2 antigens: modulation of the cells with specific antibody. Eur J Immunol 1989;19:675-680.
33. Loder F, Mutschler B, Ray RJ, Paige CJ, Sideras P, Torres R, et al.: B cell development in the spleen takes place in discrete steps and is determined by the quality of B cell receptor-derived signals. J Exp Med 1999; 190:75-89.
34. Timens W, Boes A, Rozeboom-Uiterwijk T, Poppema S: Immaturity of the human splenic marginal zone in infancy. Possible contribution to the deficient infant immune response. J Immunol 1989;143:3200-3206.
35. Rijkers GT, Sanders EA, Breukels MA, Zegers BJ: Infant B cell responses to polysaccharide determinants. Vaccine 1998;16:1396-1400.
36. Martin F, Oliver AM, Kearney JF: Marginal zone and B1 B cells unite in the early response against T-independent blood-borne particulate antigens. Immunity 2001;14: 617-629.
37. Guinamard R, Okigaki M, Schlessinger J, Ravetch JV: Absence of marginal zone B cells in Pyk-2-deficient mice defines their role in the humoral response. Nat Immunol 2000;1:31-36.
38. Halista SM, Johnson-Robbins LA, El-Mohandes AE, Lees A, Mond JJ, Katona IM: Characterization of early activation events in cord blood B cells after stimulation with T cell-independent activators. Pediatr Res 1998;43:496-503.
39. Haas KM, Hasegawa M, Steeber DA, Poe JC, Zabel MD, Bock CB, et al.: Complement receptors CD21/35 link innate and protective immunity during Streptococcus pneumoniae infection by regulating IgG3 antibody responses. Immunity 2002;17:713-723.
40. Freedman AS, Freeman G, Whitman J, Segil J, Daley J, Nadler LM: Pre-exposure of human B cells to recombinant IL-1 enhances subsequent proliferation. J Immunol 1988;141:3398-3404.
41. Bessler H, Komlos L, Punsky I, Ntambi JA, Bergman M, Straussberg R, Sirota L: CD14 receptor expression and lipopolysaccharide-induced cytokine production in preterm and term neonates. Biol Neonate 2001;80: 186-192.
42. Cohen L, Haziot A, Shen DR, Lin XY, Sia C, Harper R, et al.: CD14-independent responses to LPS require a serum factor that is absent from neonates. J Immunol 1995;155:5337-5342.
43. Hebra A, Strange P, Egbert JM, Ali M, Mullinax A, Buchanan E: Intracellular cytokine production by fetal and adult monocytes. J Pediatr Surg 2001;36:1321-1326.
44. Peters AM, Bertram P, Gahr M, Speer CP: Reduced secretion of interleukin-1 and tumor necrosis factor-alpha by neonatal monocytes. Biol Neonate 1993;63:157-162.
45. Weatherstone KB, Rich EA: Tumor necrosis factor/ cachectin and interleukin-1 secretion by cord blood monocytes from premature and term neonates. Pediatr Res 1989;25:342-346.
46. Glover DM, Brownstein D, Burchett S, Larsen A, Wilson CB: Expression of HLA class II antigens and secretion of interleukin-1 by monocytes and macrophages from adults and neonates. Immunology 1987;61:195-201.
47. Pillay V, Savage N, Laburn H: Circulating cytokine concentrations and cytokine production by monocytes from newborn babies and adults. Pflugers Arch 1994;428: 197-201.
48. Schibler KR, Liechty KW, White WL, Rothstein G, Christensen RD: Defective production of interleukin-6 by monocytes: a possible mechanism underlying several host defense deficiencies of neonates. Pediatr Res 1992;31:18-21.
49. Berner, R, Csorba J, Brandis M: Different cytokine expression in cord blood mononuclear cells after stimulation with neonatal sepsis or colonizing strains of Streptococcus agalactiae. Pediatr Res 2001;49:691-697.
50. Muller K, Zak M, Nielsen S, Pedersen FK, de Nully P, Bendtzen K: In vitro cytokine production and phenotype expression by blood mononuclear cells from umbilical cords, children and adults. Pediatr Allergy Immunol 1996;7:117-124.
51. Karlsson H, Hessle C, Rudin A: Innate immune responses of human neonatal cells to bacteria from the normal gastrointestinal flora. Infect Immun 2002;70: 6688-6696.
52. Bryson YJ, Winter HS, Gard SE, Fischer TJ, Stiehm ER: Deficiency of immune interferon production by leukocytes of normal newborns. Cell Immunol 1980;55:191-200.
53. Balazs M, Martin F, Zhou T, Kearney J: Blood dendritic cells interact with splenic marginal zone B cells to initiate T-independent immune responses. Immunity 2002;17:341-352.
54. Langrish CL, Buddle JC, Thrasher AJ, Goldblatt D: Neonatal dendritic cells are intrinsically biased against Th-1 immune responses. Clin Exp Immunol 2002;128: 118-123.
55. Liu E, Tu W, Law HK, Lau YL: Decreased yield, phenotypic expression and function of immature monocyte-derived dendritic cells in cord blood. Br J Haematol 2001;113:240-246.
56. Lafontaine M, Landry D, Blanc-Brunat N, Pelletier M, Montplaisir S: IL-1 production by human thymic dendritic cells: studies on the interrelation with DC accessory function. Cell Immunol 1991;135:431-444.
57. Ismaili J, Rennesson J, Aksoy E, Vekemans J, Vincart B, Amraoui Z, et al.: Monophosphoryl lipid A activates both human dendritic cells and T cells. J Immunol 2002;168:926-932.
58. Baker PJ, Hiernaux, JR, Fauntleroy MB, Prescott B, Cantrell JL, Rudbach JA: Inactivation of suppressor T-cell activity by nontoxic monophosphoryl lipid A. Infect Immun 1988a;56:1076-1083.
59. Baker PJ, Hiernaux JR, Fauntleroy MB, Stashak PW, Prescott B, Cantrell JL, Rudbach JA: Ability of monophosphoryl lipid A to augment the antibody response of young mice. Infect Immun 1988b;56:3064-3066.
60. Garg M, Subbarao B: Immune responses of systemic and mucosal lymphoid organs to Pnu-Imune vaccine as a function of age and the efficacy of monophosphoryl lipid A as an adjuvant. Infect Immun 1992;60:2329-2336.
61. Krieg AM, Yi AK, Matson S, Waldschmidt TJ, Bishop GA, Teasdale R, et al.: CpG motifs in bacterial DNA trigger direct B-cell activation. Nature 1995;374:546-549.
62. Chelvarajan RL, Raithatha R, Venkataraman C, Kaul R, Han SS, Robertson DA, Bondada S: CpG oligodeoxynucleotides overcome the unresponsiveness of neonatal B cells to stimulation with the thymus-independent stimuli anti-IgM and TNP-Ficoll. Eur J Immunol 1999; 29:2808-2818.
63. Kovarik J, Bozzotti P, Tougne C, Davis HL, Lambert PH, Krieg AM, Siegrist CA: Adjuvant effects of CpG oligodeoxynucleotides on responses against T-independent type 2 antigens. Immunology 2001;102:67-76.
64. Pichyangkul S, Yongvanitchit K, Kum-arb U, Krieg AM, Heppner DG, Walsh DS: Whole blood cultures to assess the immunostimulatory activities of CpG oligodeoxynucleotides. J Immunol Methods 2001;247:83-94.
65. Hartmann G, Krieg AM: Mechanism and function of a newly identified CpG DNA motif in human primary B cells. J Immunol 2000;164:944-953.