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Loss of alpha3/alpha4(IV) collagen from the glomerular basement membrane induces a strain-dependent isoform switch to alpha5alpha6(IV) collagen associated with longer renal survival in Col4a3-/- Alport mice
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Isoform switching of type IV collagen is developmentally arrested in X-linked Alport syndrome leading to increased susceptibility of renal basement membranes to endoproteolysis
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Bone-marrow-derived stem cells repair basement membrane collagen defects and reverse genetic kidney disease
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Bone marrow derived-cells contribute to podocyte regeneration and amelioration of renal disease in a mouse model of Alport syndrome
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Irradiation prolongs survival of Alport mice
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Integrin alpha1beta1 and transforming growth factor-beta1 play distinct roles in Alport glomerular pathogenesis and serve as dual targets for metabolic therapy
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Determinants of vascular permeability in the kidney glomerulus
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Molecular and functional defects in kidneys of mice lacking collagen alpha 3(IV): Implications for Alport syndrome
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Stage-specific action of matrix metalloproteinases influences progressive hereditary kidney disease
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