Irradiation prolongs survival of alport mice

Journal of the American Society of Nephrology

Volumn 19, Issue 9, 2008, Pages 1692-1700

  Katayama, Kan ^a   Kawano, Mitsuo ^a   Naito, Ichiro ^b   Ishikawa, Hitoshi ^c   Sado, Yoshikazu ^d   Asakawa, Nagisa ^a   Murata, Tomohiro ^a   Oosugi, Kazuki ^a   Kiyohara, Michiyo ^a   Ishikawa, Eiji ^a   Ito, Masaaki ^a   Nomura, Shinsuke ^a  

^a MIE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OKAYAMA UNIVERSITY   (Japan)

^c YAMAGATA UNIVERSITY   (Japan)

^d Shigei Medical Research Institute   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 4; AUTOANTIGEN; TYPE IV COLLAGEN ALPHA3 CHAIN;

ALPORT SYNDROME; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; BONE MARROW TRANSPLANTATION; FEMALE; GLOMERULUS BASEMENT MEMBRANE; GRAFT SURVIVAL; HISTOPATHOLOGY; IRRADIATION; KNOCKOUT MOUSE; MALE; NONHUMAN; PRIORITY JOURNAL; RADIATION DOSE; RAT STRAIN; SURVIVAL TIME; ANIMAL; ELECTRON MICROSCOPY; FLUORESCENCE IN SITU HYBRIDIZATION; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; KIDNEY; KIDNEY FUNCTION TEST; METABOLISM; MOUSE; MOUSE MUTANT; NEPHRITIS; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TIME; ULTRASTRUCTURE; WESTERN BLOTTING; WHOLE BODY RADIATION; Y CHROMOSOME;

ANIMALS; AUTOANTIGENS; BLOTTING, WESTERN; BONE MARROW TRANSPLANTATION; COLLAGEN TYPE IV; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; IN SITU HYBRIDIZATION, FLUORESCENCE; KIDNEY; KIDNEY FUNCTION TESTS; MALE; MICE; MICE, KNOCKOUT; MICROSCOPY, ELECTRON; NEPHRITIS, HEREDITARY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TIME FACTORS; WHOLE-BODY IRRADIATION; Y CHROMOSOME;

EID: 54749128283     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2007070829     Document Type: Article

References (25)

1. Alport AC: Hereditary familial congenital haemorrhagic nephritis. BMJ 1: 504-506, 1927
2. Barker DF, Hostikka SL, Zhou J, Chow LT, Oliphant AR, Gerken SC, Gregory MC, Skolnick MH, Atkin CL, Tryggvason K: Identification of mutations in the COL4A5 collagen gene in Alport syndrome. Science 248: 1224-1227, 1990
3. Mochizuki T, Lemmink HH, Mariyama M, Antignac C, Gubler MC, Pirson Y, Verellen-Dumoulin C, Chan D, Schroder CH, Smeets HJ, Reeders ST: Identification of mutations in the alpha 3(IV) and alpha 4(IV) collagen genes in autosomal recessive Alport syndrome. Nat Genet 8: 77-81, 1994
4. Gross O, Beirowski B, Koepke ML, Kuck J, Reiner M, Addicks K, Smyth N, Schulze-Lohoff E, Weber M: Preemptive ramipril therapy delays renal failure and reduces renal fibrosis in COL4A3-knockout mice with Alport syndrome. Kidney Int 63: 438-446, 2003
5. Gross O, Schulze-Lohoff E, Koepke ML, Beirowski B, Addicks K, Bloch W, Smyth N, Weber M: Antifibrotic, nephroprotective potential of ACE inhibitor vs AT1 antagonist in a murine model of renal fibrosis. Nephrol Dial Transplant 19: 1716-1723, 2004
6. Chen D, Jefferson B, Harvey SJ, Zheng K, Gartley CJ, Jacobs RM, Thorner PS: Cyclosporin a slows the progressive renal disease of Alport syndrome (X-linked hereditary nephritis): Results from a canine model. J Am Soc Nephrol 14: 690-698, 2003
7. Charbit M, Gubler MC, Dechaux M, Gagnadoux MF, Grunfeld JP, Niaudet P: Cyclosporin therapy in patients with Alport syndrome. Pediatr Nephrol 22: 57-63, 2007
8. Heikkila P, Parpala T, Lukkarinen O, Weber M, Tryggvason K: Adenovirus-mediated gene transfer into kidney glomeruli using an ex vivo and in vivo kidney perfusion system: First steps towards gene therapy of Alport syndrome. Gene Ther 3: 21-27, 1996
9. Heikkila P, Tibell A, Morita T, Chen Y, Wu G, Sado Y, Ninomiya Y, Pettersson E, Tryggvason K: Adenovirus-mediated transfer of type IV collagen alpha 5 chain cDNA into swine kidney in vivo: Deposition of the protein into the glomerular basement membrane. Gene Ther 8: 882-890, 2001
10. Sugimoto H, Mundel TM, Sund M, Xie L, Cosgrove D, Kalluri R: Bone-marrow-derived stem cells repair basement membrane collagen defects and reverse genetic kidney disease. Proc Natl Acad Sci U S A 103: 7321-7326, 2006
11. Prodromidi EI, Poulsom R, Jeffery R, Roufosse CA, Pollard PJ, Pusey CD, Cook HT: Bone marrow-derived cells contribute to podocyte regeneration and amelioration of renal disease in a mouse model of Alport syndrome. Stem Cells 24: 2448-2455, 2006
12. Floege J, Kunter U, Weber M, Gross O: Bone marrow transplantation rescues Alport mice. Nephrol Dial Transplant 21: 2721-2723, 2006
13. Kang JS, Wang XP, Miner JH, Morello R, Sado Y, Abrahamson DR, Borza DB: Loss of alpha3/alpha4 (IV) collagen from the glomerular basement membrane induces a strain-dependent isoform switch to alpha5alpha6 (IV) collagen associated with longer renal survival in Col4a3-/- Alport mice. J Am Soc Nephrol 17: 1962-1969, 2006
14. Molteni A, Moulder JE, Cohen EP, Fish BL, Taylor JM, Veno PA, Wolfe LF, Ward WF: Prevention of radiation-induced nephropathy and fibrosis in a model of bone marrow transplant by an angiotensin II receptor blocker. Exp Biol Med 226: 1016-1023, 2001
15. Moulder JE, Fish BL, Regner KR, Cohen EP, Raife TJ: Retinoic acid exacerbates experimental radiation nephropathy. Radiat Res 157: 199-203, 2002
16. Safwat A, Nielsen OS, El-Badawy S, Overgaard J: Late renal damage after total body irradiation and bone marrow transplantation in a mouse model: Effect of radiation fractionation. Eur J Cancer 31A: 987-992, 1995
17. Guo JK, Schedl A, Krause DS: Bone marrow transplantation can attenuate the progression of mesangial sclerosis. Stem Cells 24: 406-415, 2006
18. Guo JK, Ardito TA, Kashgarian M, Krause DS: Prevention of mesangial sclerosis by bone marrow transplantation. Kidney Int 70: 910-913, 2006
19. Kruse JJ, te Poele JA, Velds A, Kerkhoven RM, Boersma LJ, Russell NS, Stewart FA: Identification of differentially expressed genes in mouse kidney after irradiation using microarray analysis. Radiat Res 161: 28-38, 2004
20. Cosgrove D, Meehan DT, Grunkemeyer JA, Kornak JM, Sayers R, Hunter WJ, Samuelson GC: Collagen COL4A3 knockout: A mouse model for autosomal Alport syndrome. Genes Dev 10: 2981-2992, 1996
21. Yokoo T, Ohashi T, Utsunomiya Y, Shen JS, Hisada Y, Eto Y, Kawamura T, Hosoya T: Genetically modified bone marrow continuously supplies anti-inflammatory cells and suppresses renal injury in mouse Good-pasture syndrome. Blood 98: 57-64, 2001
22. Boffa JJ, Lu Y, Placier S, Stefanski A, Dussaule JC, Chatziantoniou C: Regression of renal vascular and glomerular fibrosis: Role of angiotensin II receptor antagonism and matrix metalloproteinases. J Am Soc Nephrol 14: 1132-1144, 2003
23. Hashimoto T, Karasawa T, Saito A, Miyauchi N, Han GD, Hayasaka K, Shimizu F, Kawachi H: Ephrin-B1 localizes at the slit diaphragm of the glomerular podocyte. Kidney Int 72: 954-964, 2007
24. Overbergh L, Valckx D, Waer M, Mathieu C: Quantification of murine cytokine mRNAs using real time quantitative reverse transcriptase PCR. Cytokine 11: 305-312, 1999
25. Langeveld JP, Wieslander J, Timoneda J, McKinney P, Butkowski RJ, Wisdom BJ Jr, Hudson BG: Structural heterogeneity of the noncollagenous domain of basement membrane collagen. J Biol Chem 263: 10481-10488, 1988