메뉴 건너뛰기




Volumn 28, Issue 4, 2008, Pages 424-431

Assessment of the prescription of antidepressant drugs in elderly nursing home patients: A clinical and laboratory follow-up investigation

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; AMITRIPTYLINE; ANTIDEPRESSANT AGENT; CITALOPRAM; CLOMIPRAMINE; CYANOCOBALAMIN; CYTOCHROME P450; DINORCITALOPRAM; DRUG METABOLITE; FLUOXETINE; FUROSEMIDE; LACTULOSE; MACROGOL; MIRTAZAPINE; NORCITALOPRAM; OXAZEPAM; PARACETAMOL; PAROXETINE; SERTRALINE; UNCLASSIFIED DRUG; VENLAFAXINE; ZOLPIDEM;

EID: 54449099519     PISSN: 02710749     EISSN: None     Source Type: Journal    
DOI: 10.1097/JCP.0b013e31817d79eb     Document Type: Article
Times cited : (16)

References (49)
  • 1
    • 0031001720 scopus 로고    scopus 로고
    • Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study
    • Murray CJ, Lopez AD. Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study. Lancet. 1997;349:1498-1504.
    • (1997) Lancet , vol.349 , pp. 1498-1504
    • Murray, C.J.1    Lopez, A.D.2
  • 2
    • 0031450167 scopus 로고    scopus 로고
    • The epidemiology of affective disorders in the elderly: A review
    • Palsson S, Skoog I. The epidemiology of affective disorders in the elderly: a review. Int Clin Psychopharmacol. 1997;12(suppl 7):S3-S13.
    • (1997) Int Clin Psychopharmacol , vol.12 , Issue.SUPPL. 7
    • Palsson, S.1    Skoog, I.2
  • 3
    • 0032569639 scopus 로고    scopus 로고
    • Association between depressive symptoms and mortality in older women. Study of Osteoporotic Fractures Research Group
    • Whooley MA, Browner WS. Association between depressive symptoms and mortality in older women. Study of Osteoporotic Fractures Research Group. Arch Intern Med. 1998;158:2129-2135.
    • (1998) Arch Intern Med , vol.158 , pp. 2129-2135
    • Whooley, M.A.1    Browner, W.S.2
  • 4
    • 11144236264 scopus 로고    scopus 로고
    • Depressive symptoms and mortality in men: Results from the Multiple Risk Factor Intervention Trial
    • Gump BB, Matthews KA, Eberly LE, et al. Depressive symptoms and mortality in men: results from the Multiple Risk Factor Intervention Trial. Stroke. 2005;36:98-102.
    • (2005) Stroke , vol.36 , pp. 98-102
    • Gump, B.B.1    Matthews, K.A.2    Eberly, L.E.3
  • 5
    • 0031952861 scopus 로고    scopus 로고
    • Newer psychotropic medication use in nursing home residents
    • Lasser RA, Sunderland T. Newer psychotropic medication use in nursing home residents. J Am Geriatr Soc. 1998;46:202-207.
    • (1998) J Am Geriatr Soc , vol.46 , pp. 202-207
    • Lasser, R.A.1    Sunderland, T.2
  • 6
    • 0036298229 scopus 로고    scopus 로고
    • Clinically significant drug interactions with anti-depressants in the elderly
    • Spina E, Scordo MG. Clinically significant drug interactions with anti-depressants in the elderly. Drugs Aging. 2002;19:299-320.
    • (2002) Drugs Aging , vol.19 , pp. 299-320
    • Spina, E.1    Scordo, M.G.2
  • 7
    • 15544362080 scopus 로고    scopus 로고
    • Clinical trials of potential antidepressants: To what extent are the elderly represented: a review
    • Giron MS, Fastbom J, Winblad B. Clinical trials of potential antidepressants: to what extent are the elderly represented: a review Int J Geriatr Psychiatry. 2005;20:201-217.
    • (2005) Int J Geriatr Psychiatry , vol.20 , pp. 201-217
    • Giron, M.S.1    Fastbom, J.2    Winblad, B.3
  • 8
    • 84891719121 scopus 로고    scopus 로고
    • A randomised controlled trial to compare the cost-effectiveness of tricyclic antidepressants, selective serotonin reuptake inhibitors and lofepramine
    • Peveler R, Kendrick T, Buxton M, et al. A randomised controlled trial to compare the cost-effectiveness of tricyclic antidepressants, selective serotonin reuptake inhibitors and lofepramine. Health Technol Assess. 2005;9:1-134.
    • (2005) Health Technol Assess , vol.9 , pp. 1-134
    • Peveler, R.1    Kendrick, T.2    Buxton, M.3
  • 10
    • 0023241882 scopus 로고
    • Determination of paroxetine in human plasma, using high-performance liquid chromatography with fluorescence detection
    • Brett MA, Dierdorf HD, Zussman BD, et al. Determination of paroxetine in human plasma, using high-performance liquid chromatography with fluorescence detection. J Chromatogr. 1987;419:438-444.
    • (1987) J Chromatogr , vol.419 , pp. 438-444
    • Brett, M.A.1    Dierdorf, H.D.2    Zussman, B.D.3
  • 11
    • 4243109692 scopus 로고    scopus 로고
    • Serum disposition of sertraline, N-desmethylsertraline and paroxetine: A pharmacokinetic evaluation of repeated drug concentration measurements during 6 months of treatment for major depression
    • Reis M, Aberg-Wistedt A, Agren H, et al. Serum disposition of sertraline, N-desmethylsertraline and paroxetine: a pharmacokinetic evaluation of repeated drug concentration measurements during 6 months of treatment for major depression. Hum Psychopharmacol. 2004;19:283-291.
    • (2004) Hum Psychopharmacol , vol.19 , pp. 283-291
    • Reis, M.1    Aberg-Wistedt, A.2    Agren, H.3
  • 12
    • 0036337642 scopus 로고    scopus 로고
    • Therapeutic drug monitoring of racemic venlafaxine and its main metabolites in an everyday clinical setting
    • Reis M, Lundmark J, Bjork H, et al. Therapeutic drug monitoring of racemic venlafaxine and its main metabolites in an everyday clinical setting. Ther DrugMonit. 2002;24:545-553.
    • (2002) Ther DrugMonit , vol.24 , pp. 545-553
    • Reis, M.1    Lundmark, J.2    Bjork, H.3
  • 13
    • 0035179512 scopus 로고    scopus 로고
    • Enantioselective analysis of citalopram and metabolites in adolescents
    • Carlsson B, Olsson G, Reis M, et al. Enantioselective analysis of citalopram and metabolites in adolescents. Ther Drug Monit. 2001;23:658-664.
    • (2001) Ther Drug Monit , vol.23 , pp. 658-664
    • Carlsson, B.1    Olsson, G.2    Reis, M.3
  • 14
    • 23244463878 scopus 로고    scopus 로고
    • Inter- and intraindividual pharmacokinetic variations of mirtazapine and its N-demethyl metabolite in patients treated for major depressive disorder: A 6-month therapeutic drug monitoring study
    • Reis M, Prochazka J, Sitsen A, et al. Inter- and intraindividual pharmacokinetic variations of mirtazapine and its N-demethyl metabolite in patients treated for major depressive disorder: a 6-month therapeutic drug monitoring study. Ther Drug Monit. 2005;27:469-477.
    • (2005) Ther Drug Monit , vol.27 , pp. 469-477
    • Reis, M.1    Prochazka, J.2    Sitsen, A.3
  • 15
    • 0035081766 scopus 로고    scopus 로고
    • Serum concentrations of fluoxetine in the clinical treatment setting
    • Lundmark J, Reis M, Bengtsson F. Serum concentrations of fluoxetine in the clinical treatment setting. Ther DrugMonit. 2001;23:139-147.
    • (2001) Ther DrugMonit , vol.23 , pp. 139-147
    • Lundmark, J.1    Reis, M.2    Bengtsson, F.3
  • 16
    • 0242637084 scopus 로고    scopus 로고
    • Identification of CYP2D6alleles by single nucleotide polymorphism analysis using pyrosequencing
    • Zackrisson AL, Lindblom B. Identification of CYP2D6alleles by single nucleotide polymorphism analysis using pyrosequencing. Eur Clin Pharmacol. 2003;59:521-526.
    • (2003) Eur Clin Pharmacol , vol.59 , pp. 521-526
    • Zackrisson, A.L.1    Lindblom, B.2
  • 17
    • 14544294868 scopus 로고    scopus 로고
    • Determination of CYP2D6gene copy number by pyrosequencing
    • Soderback E, Zackrisson AL, Lindblom B, et al. Determination of CYP2D6gene copy number by pyrosequencing. Clin Chem. 2005;51:522-531.
    • (2005) Clin Chem , vol.51 , pp. 522-531
    • Soderback, E.1    Zackrisson, A.L.2    Lindblom, B.3
  • 18
    • 0042843050 scopus 로고    scopus 로고
    • Cytochrome P450 genotyping by multiplexed real-time dna sequencing with pyrosequencing technology
    • Eriksson S, Berg LM, Wadelius M, et al. Cytochrome P450 genotyping by multiplexed real-time dna sequencing with pyrosequencing technology. Assay DrugDev Technol. 2002;1:49-59.
    • (2002) Assay DrugDev Technol , vol.1 , pp. 49-59
    • Eriksson, S.1    Berg, L.M.2    Wadelius, M.3
  • 19
    • 33845988396 scopus 로고    scopus 로고
    • Metabolic drug interactions with newer antipsychotics: A comparative review
    • Spina E, de Leon J. Metabolic drug interactions with newer antipsychotics: a comparative review. Basic Clin Pharmacol Toxicol. 2007;100:4-22.
    • (2007) Basic Clin Pharmacol Toxicol , vol.100 , pp. 4-22
    • Spina, E.1    de Leon, J.2
  • 20
    • 0031908744 scopus 로고    scopus 로고
    • Venkatakrishnan K, Greenblatt DJ, von Moltke LL, et al. Five distinct human cytochromes mediate amitriptyline N-demethylation in vitro: dominance of CYP 2C19and 3A4. J Clin Pharmacol. 1998; 38:112-121.
    • Venkatakrishnan K, Greenblatt DJ, von Moltke LL, et al. Five distinct human cytochromes mediate amitriptyline N-demethylation in vitro: dominance of CYP 2C19and 3A4. J Clin Pharmacol. 1998; 38:112-121.
  • 21
    • 0030425332 scopus 로고    scopus 로고
    • The biotransformation of clomipramine in vitro, identification of the cytochrome P450s responsible for the separate metabolic pathways
    • Nielsen KK, Flinois JP, Beaune P, et al. The biotransformation of clomipramine in vitro, identification of the cytochrome P450s responsible for the separate metabolic pathways. J Pharmacol Exp Ther. 1996; 277:1659-1664.
    • (1996) J Pharmacol Exp Ther , vol.277 , pp. 1659-1664
    • Nielsen, K.K.1    Flinois, J.P.2    Beaune, P.3
  • 22
    • 4444356636 scopus 로고    scopus 로고
    • Therapeutic drug monitoring of psychotropic drugs. TDM nouveau
    • Bengtsson F. Therapeutic drug monitoring of psychotropic drugs. TDM "nouveau." Ther Drug Monit. 2004;26:145-151.
    • (2004) Ther Drug Monit , vol.26 , pp. 145-151
    • Bengtsson, F.1
  • 24
    • 0033865135 scopus 로고    scopus 로고
    • Therapeutic drug monitoring of sertraline: Variability factors as displayed in a clinical setting
    • Lundmark J, Reis M, Bengtsson F. Therapeutic drug monitoring of sertraline: variability factors as displayed in a clinical setting. Ther Drug Monit. 2000;22:446-454.
    • (2000) Ther Drug Monit , vol.22 , pp. 446-454
    • Lundmark, J.1    Reis, M.2    Bengtsson, F.3
  • 25
    • 9744251578 scopus 로고    scopus 로고
    • The AGNP-TDM expert group consensus guidelines: Therapeutic drug monitoring in psychiatry
    • Baumann P, Hiemke C, Ulrich S, et al. The AGNP-TDM expert group consensus guidelines: therapeutic drug monitoring in psychiatry. Pharmacopsychiatry. 2004;37:243-65.
    • (2004) Pharmacopsychiatry , vol.37 , pp. 243-265
    • Baumann, P.1    Hiemke, C.2    Ulrich, S.3
  • 26
    • 0037380879 scopus 로고    scopus 로고
    • Therapeutic drug monitoring of racemic citalopram: A 5-year experience in Sweden, 1992-1997
    • Reis M, Lundmark J, Bengtsson F. Therapeutic drug monitoring of racemic citalopram: a 5-year experience in Sweden, 1992-1997. Ther Drug Monit. 2003;25:183-191.
    • (2003) Ther Drug Monit , vol.25 , pp. 183-191
    • Reis, M.1    Lundmark, J.2    Bengtsson, F.3
  • 27
    • 3142519666 scopus 로고    scopus 로고
    • Pharmacogenetics of antidepressants and antipsychotics: The contribution of allelic variations to the phenotype of drug response
    • Kirchheiner J, Nickchen K, Bauer M, et al. Pharmacogenetics of antidepressants and antipsychotics: the contribution of allelic variations to the phenotype of drug response. Mol Psychiatry. 2004;9:442-473.
    • (2004) Mol Psychiatry , vol.9 , pp. 442-473
    • Kirchheiner, J.1    Nickchen, K.2    Bauer, M.3
  • 28
    • 0020431887 scopus 로고
    • Kinetics of citalopram in test animals; drug exposure in safety studies
    • Fredricson Overo K. Kinetics of citalopram in test animals; drug exposure in safety studies. Prog Neuropsychopharmacol Biol Psychiatry. 1982;6:297-309.
    • (1982) Prog Neuropsychopharmacol Biol Psychiatry , vol.6 , pp. 297-309
    • Fredricson Overo, K.1
  • 29
    • 85017265899 scopus 로고    scopus 로고
    • Psychotropic drug use in nursing homes-diagnostic indications and variations between institutions
    • Ruths S, Straand J, Nygaard HA. Psychotropic drug use in nursing homes-diagnostic indications and variations between institutions. Eur J Clin Pharmacol. 2001;57:523-528.
    • (2001) Eur J Clin Pharmacol , vol.57 , pp. 523-528
    • Ruths, S.1    Straand, J.2    Nygaard, H.A.3
  • 30
    • 33645451779 scopus 로고    scopus 로고
    • Prevalence and predictors of depression in populations of elderly: A review
    • Djernes JK. Prevalence and predictors of depression in populations of elderly: a review. Acta Psychiatr Scand. 2006;113:372-387.
    • (2006) Acta Psychiatr Scand , vol.113 , pp. 372-387
    • Djernes, J.K.1
  • 31
    • 0141593543 scopus 로고    scopus 로고
    • Metabolic drug interactions with new psychotropic agents
    • Spina E, Scordo MG, D'Arrigo C. Metabolic drug interactions with new psychotropic agents. Fundam Clin Pharmacol. 2003;17:517-538.
    • (2003) Fundam Clin Pharmacol , vol.17 , pp. 517-538
    • Spina, E.1    Scordo, M.G.2    D'Arrigo, C.3
  • 32
    • 0034124795 scopus 로고    scopus 로고
    • The development of polypharmacy. A longitudinal study
    • Veehof L, Stewart R, Haaijer-Ruskamp F, et al. The development of polypharmacy. A longitudinal study. Fam Pract. 2000;17:261-267.
    • (2000) Fam Pract , vol.17 , pp. 261-267
    • Veehof, L.1    Stewart, R.2    Haaijer-Ruskamp, F.3
  • 33
    • 0031746034 scopus 로고    scopus 로고
    • Important drug-drug interactions in the elderly
    • Seymour RM, Routledge PA. Important drug-drug interactions in the elderly. Drugs Aging. 1998;12:485-494.
    • (1998) Drugs Aging , vol.12 , pp. 485-494
    • Seymour, R.M.1    Routledge, P.A.2
  • 34
    • 0347319044 scopus 로고    scopus 로고
    • Age-related changes in pharmacokinetics and pharmacodynamics: Basic principles and practical applications
    • Mangoni AA, Jackson SH. Age-related changes in pharmacokinetics and pharmacodynamics: basic principles and practical applications. Br JClin Pharmacol. 2004;57:6-14.
    • (2004) Br JClin Pharmacol , vol.57 , pp. 6-14
    • Mangoni, A.A.1    Jackson, S.H.2
  • 35
    • 0034844208 scopus 로고    scopus 로고
    • Calculation of the estimated creatinine clearance in avoiding drug dosing errors in the older patient
    • Hu KT, Matayoshi A, Stevenson FT. Calculation of the estimated creatinine clearance in avoiding drug dosing errors in the older patient. Am J Med Sci. 2001;322:133-136.
    • (2001) Am J Med Sci , vol.322 , pp. 133-136
    • Hu, K.T.1    Matayoshi, A.2    Stevenson, F.T.3
  • 36
    • 0345060779 scopus 로고    scopus 로고
    • Polymorphisms in the CYP 2D6gene: Association with plasma concentrations of fluoxetine and paroxetine
    • Charlier C, Broly F, Lhermitte M, et al. Polymorphisms in the CYP 2D6gene: association with plasma concentrations of fluoxetine and paroxetine. Ther Drug Monit. 2003;25:738-742.
    • (2003) Ther Drug Monit , vol.25 , pp. 738-742
    • Charlier, C.1    Broly, F.2    Lhermitte, M.3
  • 37
    • 33745914214 scopus 로고    scopus 로고
    • CYP2D6genotype and venlafaxine-XR concentrations in depressed elderly
    • Whyte EM, Romkes M, Mulsant BH, et al. CYP2D6genotype and venlafaxine-XR concentrations in depressed elderly. Int J Geriatr Psychiatry. 2006;21:542-549.
    • (2006) Int J Geriatr Psychiatry , vol.21 , pp. 542-549
    • Whyte, E.M.1    Romkes, M.2    Mulsant, B.H.3
  • 38
    • 0035163962 scopus 로고    scopus 로고
    • Selective serotonin-reuptake inhibitor anti- depressants increase the risk of falls and hip fractures in elderly people by inhibiting cardiovascular ion channels
    • Pacher P, Ungvari Z. Selective serotonin-reuptake inhibitor anti- depressants increase the risk of falls and hip fractures in elderly people by inhibiting cardiovascular ion channels. Med Hypotheses. 2001;57:469-471.
    • (2001) Med Hypotheses , vol.57 , pp. 469-471
    • Pacher, P.1    Ungvari, Z.2
  • 39
    • 0032766653 scopus 로고    scopus 로고
    • Drug-induced cognition disorders in the elderly: Incidence, prevention and management
    • Gray SL, Lai KV, Larson EB. Drug-induced cognition disorders in the elderly: incidence, prevention and management. Drug Saf. 1999;21:101-122.
    • (1999) Drug Saf , vol.21 , pp. 101-122
    • Gray, S.L.1    Lai, K.V.2    Larson, E.B.3
  • 40
    • 33750600216 scopus 로고    scopus 로고
    • Antidepressants in older persons
    • Swan A. Antidepressants in older persons. Am Fam Physician. 2006;74:1503.
    • (2006) Am Fam Physician , vol.74 , pp. 1503
    • Swan, A.1
  • 41
    • 2442700128 scopus 로고    scopus 로고
    • Severe adverse drug reactions of antidepressants: Results of the German multicenter drug surveillance program AMSP
    • Degner D, Grohmann R, Kropp S, et al. Severe adverse drug reactions of antidepressants: results of the German multicenter drug surveillance program AMSP. Pharmacopsychiatry. 2004;37(suppl 1):S39-S45.
    • (2004) Pharmacopsychiatry , vol.37 , Issue.SUPPL. 1
    • Degner, D.1    Grohmann, R.2    Kropp, S.3
  • 42
    • 0035934609 scopus 로고    scopus 로고
    • Inhibition of serotonin reuptake by antidepressants and upper gastrointestinal bleeding in elderly patients: Retrospective cohort study
    • van Walraven C, Mamdani MM, Wells PS, et al. Inhibition of serotonin reuptake by antidepressants and upper gastrointestinal bleeding in elderly patients: retrospective cohort study. BMJ. 2001;323:655-658.
    • (2001) BMJ , vol.323 , pp. 655-658
    • van Walraven, C.1    Mamdani, M.M.2    Wells, P.S.3
  • 43
    • 0033051316 scopus 로고    scopus 로고
    • Adverse reactions of selective serotonin reuptake inhibitors: Reports from a spontaneous reporting system
    • Spigset O. Adverse reactions of selective serotonin reuptake inhibitors: reports from a spontaneous reporting system. Drug Saf. 1999;20:277-287.
    • (1999) Drug Saf , vol.20 , pp. 277-287
    • Spigset, O.1
  • 44
    • 0035010793 scopus 로고    scopus 로고
    • Who develops severe or fatal adverse drug reactions to selective serotonin reuptake inhibitors?
    • Dalfen AK, Stewart DE. Who develops severe or fatal adverse drug reactions to selective serotonin reuptake inhibitors? Can J Psychiatry. 2001;46:258-263.
    • (2001) Can J Psychiatry , vol.46 , pp. 258-263
    • Dalfen, A.K.1    Stewart, D.E.2
  • 45
    • 33745512079 scopus 로고    scopus 로고
    • Appropriateness of therapeutic drug monitoring for antidepressants in routine psychiatric inpatient care
    • Mann K, Hiemke C, Schmidt LG, et al. Appropriateness of therapeutic drug monitoring for antidepressants in routine psychiatric inpatient care. Ther Drug Monit. 2006;28:83-88.
    • (2006) Ther Drug Monit , vol.28 , pp. 83-88
    • Mann, K.1    Hiemke, C.2    Schmidt, L.G.3
  • 46
    • 9744221188 scopus 로고    scopus 로고
    • Fastbom J, Schmidt I. Shortages in the treatment of depression of the elderly in nursing homes in Stockholm. Diagnosis is based on flimsy ground, follow up performed early. Lakartidningen. 2004;101:3683-3684, 3686-3688.
    • Fastbom J, Schmidt I. Shortages in the treatment of depression of the elderly in nursing homes in Stockholm. Diagnosis is based on flimsy ground, follow up performed early. Lakartidningen. 2004;101:3683-3684, 3686-3688.
  • 47
    • 1642406951 scopus 로고    scopus 로고
    • Two out of three persons living in nursing homes for the elderly are treated with at least ten different drugs. A survey of drug prescriptions in the northeastern part of Skane
    • Kragh A. Two out of three persons living in nursing homes for the elderly are treated with at least ten different drugs. A survey of drug prescriptions in the northeastern part of Skane. Lakartidningen. 2004;101:994-996, 999.
    • (2004) Lakartidningen , vol.101 , Issue.994-996 , pp. 999
    • Kragh, A.1
  • 48
    • 0347361483 scopus 로고    scopus 로고
    • Controlled withdrawal of selective serotonin reuptake inhibitor drugs in elderly patients in nursing homes with no indication of depression
    • Ulfvarson J, Adami J, Wredling R, et al. Controlled withdrawal of selective serotonin reuptake inhibitor drugs in elderly patients in nursing homes with no indication of depression. Eur JClin Pharmacol. 2003;59:735-740.
    • (2003) Eur JClin Pharmacol , vol.59 , pp. 735-740
    • Ulfvarson, J.1    Adami, J.2    Wredling, R.3
  • 49
    • 1642458350 scopus 로고    scopus 로고
    • Diabetes control in Swedish community dwelling elderly: More often tight than poor
    • Lofgren UB, Rosenqvist U, Lindstrom T, et al. Diabetes control in Swedish community dwelling elderly: more often tight than poor. J Intern Med. 2004;255:96-101.
    • (2004) J Intern Med , vol.255 , pp. 96-101
    • Lofgren, U.B.1    Rosenqvist, U.2    Lindstrom, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.