Controlled withdrawal of selective serotonin reuptake inhibitor drugs in elderly patients in nursing homes with no indication of depression

European Journal of Clinical Pharmacology

Volumn 59, Issue 10, 2003, Pages 735-740

  Ulfvarson, Johanna ^a,b   Adami, Johanna ^b   Wredling, Regina ^b   Kjellman, Bengt ^c   Reilly, Marie ^b   Von Bahr, Christer ^a  

^a STOCKHOLM SÖDER HOSPITAL   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c ST GÖRAN S HOSPITAL   (Sweden)

Author keywords

Nursing homes; SSRI drugs; Withdrawal

Indexed keywords

CITALOPRAM; SEROTONIN UPTAKE INHIBITOR; SERTRALINE;

ADULT; AGED; ANXIETY DISORDER; ARTICLE; CONSTIPATION; CONTROLLED STUDY; DEMENTIA; DEPRESSION; DIZZINESS; DRUG INDICATION; DRUG WITHDRAWAL; FATIGUE; FEMALE; HEADACHE; HEART DISEASE; HUMAN; INSOMNIA; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; MONTGOMERY ASBERG DEPRESSION RATING SCALE; NAUSEA; NURSING HOME; OUTCOMES RESEARCH; PRIORITY JOURNAL; RATING SCALE; SIDE EFFECT; SWEATING; SWEDEN; TREMOR; WEIGHT REDUCTION; XEROSTOMIA;

AGED; AGED, 80 AND OVER; DEPRESSIVE DISORDER; DRUG ADMINISTRATION SCHEDULE; FEMALE; HUMANS; MALE; NURSING HOMES; PSYCHIATRIC STATUS RATING SCALES; SEROTONIN UPTAKE INHIBITORS; TIME FACTORS;

EID: 0347361483     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00228-003-0687-y     Document Type: Article

References (31)

1. Pitkala KH, Strandberg TE, Tilvis RS (2001) Is it possible to reduce polypharmacy in the elderly? A randomized, controlled trial. Drugs Aging 18:143-149
2. Barat I, Andreasen F, Damsgaard EM (2000) The consumption of drugs by 75-year-old individuals living in their own homes. Eur J Clin Pharmacol 56:501-509
3. Furniss L, Lloyd Craig K, Burns A (1998) Medication use in nursing homes for elderly people. Int J Geriatr Psychiatry 13:433-439
4. Bhatia SC, Bathia SK (1997) Major depression: selecting safe and effective treatment. Am Fam Physician 55:1683-1698
5. Muijser RB, Plosker GL, Noble S (2002) Sertraline: a review of its use in the management of major depressive disorder in elderly patients. Drugs Aging 19:377-392
6. Serby M, Yu M (2003) Overview. Depression in the elderly. Mt Sinai J Med 70:38-44
7. Barkin RL, Schwer WA, Barkin SJ (2000) Recognition and management of depression in primary care: a focus on the elderly. A pharmacotherapeutic overview of the selection process among the traditional and new antidepressant. Am J Ther 7:205-226
8. Cole MG, Elie LM, McCuster J, Bellavance F, Mansour A (2000) Feasibility and effectiveness of treatment for depression in elderly medical inpatients: a systematic review. Int Psychogeriatr 12:453-461
9. Steiner D, Marcopulos B (1991) Depression in the elderly. Characteristics and clinical management. Nurs Clin North Am 26:585-600
10. Bell M, Goss AJ (2001) Recognition, assessment and treatment of depression in geriatric nursing home residents. Clin Excell Nurse Pract 5:26-36
11. Nyth AL, Gottfries CG, Lyby K, Smedegaard-Andersen L, Gylding-Sabroe J, Kristensen M et al (1992) A controlled multicenter clinical study of citalopram and placebo in elderly depressed patients with and without concomitant dementia. Acta Psychiatr Scand 86:138-145
12. Kates N, Crustolo AM, Farrar S, Nikolaou L (2002) Counselors in primary care: benefits and lessons learned. Can J Psychiatry 47:857-862
13. Scott J, Thorne A, Horn P (2002) Quality improvement report: effect of a multifaceted approach to detecting and managing depression in primary care. BMJ 26:951-954
14. American Psychiatric Association. (2000) Diagnostic and statistical manual of mental disorders: DSM-IV, 4th edn. American Psychiatric Association, Washington, DC
15. Mottram P, Wilson K, Copeland J (2000) Validation of the Hamilton Depression Rating Scale and Montgomery and Åsberg Rating Scales in terms of AGECAT depression cases. Int J Geriatr Psychiatry 15:1113-1193
16. Brown MN, Lapane KL, Luisi AF (2002) The management of depression in older nursing home residents. J Am Geriatr Soc 50:69-76
17. Montgomery SA, Åsberg M (1979) A new depression scale designed to be sensitive to change. Br J Psychiatry 134:383-389
18. Bodlund O, Kullgren G, Ekselius L, Lindström E, von Knorring L (1994) Axis V - Global Assessment of Functioning. Evaluation of a self-report version. Acta Psychiatr. Scand. 90:342-347
19. Startup M, Jackson MC, Bendix S (2002) The concurrent validity of the Global Assessment of Functioning (GAF). Br J Clin Psychol 41:417-422
20. Forsberg C, Björvell H (1993) Swedish population norms for the GHRI, HI and STAI-state. Qual Life Res 2:349-356
21. Medical Products Agency's Code of Statutes (2001) LVFS 12 ISSN 1101-5225
22. Muijsers RB, Plosker GL, Noble S (2002) Spotlight on sertraline in the management of major depressive disorder in elderly patients. CNS Drugs 16:789-794
23. Ulfvarson J, Adami J, Ullman B, Wredling R, Reilly M, von Bahr C (2003) Randomized controlled intervention in cardiovascular drug treatment in nursing homes. Pharmacoepidemiol Drug Safety 12:589-593
24. McDonald WM, Salzman C, Schatzberg AF (2002) Depression in the elderly. Psychopharmacol Bull 36[Suppl 2]:121-122
25. Ekselius L, von Knorring L, Eberhard G (1997) A double-blind multicenter trial comparing sertraline and citalopram in patients with major depression treated in general practice. Int Clin Psychopharmacol 12:323-331
26. Stahl SM (2000) Placebo-controlled comparison of the selective serotonin reuptake inhibitor citalopram and sertraline. Biol. Psychiatry 48:894-901
27. Liu B, Anderson G, Mittmann N, To T, Axcell T, Shear N (1998) Use of selective serotonin-reuptake inhibitors or tricyclic antidepressants and risk of hip fractures in elderly people. Lancet 351:1303-1307
28. Pacher P, Ungvari Z (2001) Selective serotonin-reuptake inhibitors antidepressants increase the risk of falls and hip fractures in elderly people by inhibiting cardiovascular ion channels. Medical Hypotheses 57:469-471
29. Movig KL, Leufkens HG, Belitser SV, Lenderink AW, Egberts AC (2002) Selective serotonin reuptake inhibitor-induced urinary incontinence. Pharmacoepidemiol. Drug Safety 4:271-279
30. Dalton SO, Johansen C, Mellemkjaer L, Norgard B, Sorensen HT, Olsen JH (2003) Use of selective serotonin reuptake inhibitors and risk of upper gastrointestinal tract bleeding: a population-based cohort study. Arch Intern Med 163:59-64
31. Movig KL, Leufkens HG, Lenderink AW, van den Akker VG, Hoidiamont PP, Goldschmidt HM, Egberts AC (2002) Association between antidepressant drug use and hyponatraemia: a case-control study. Br J Clin Pharmacol 53:363-369