Urokinase-type plasminogen activator receptor induces conformational changes in the integrin αMβ2 headpiece and reorientation of its transmembrane domains

Journal of Biological Chemistry

Volumn 283, Issue 37, 2008, Pages 25392-25403

  Tang, Man Li ^a   Vararattanavech, Ardcharaporn ^a   Tan, Suet Mien ^a  

^a NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; ADHESION; ANTIBODIES; CELL ADHESION; CELL MEMBRANES; ENERGY TRANSFER; FLUORESCENCE; MOLECULES; MONOCLONAL ANTIBODIES;

CELL ADHESION MOLECULES; CONFORMATIONAL CHANGES; CYTOPLASMIC DOMAINS; CYTOPLASMIC TAILS; ECTODOMAIN; FLUORESCENCE RESONANCE ENERGY TRANSFER ANALYSES; GLYCOSYLPHOSPHATIDYL INOSITOLS; INTEGRIN; INTEGRINS; PLASMINOGEN ACTIVATORS; TRANSMEMBRANE DOMAINS;

CONFORMATIONS;

ALPHA INTEGRIN; HYBRID PROTEIN; INTEGRIN ALPHAMBETA2; MONOCLONAL ANTIBODY; PLASMINOGEN ACTIVATOR; PROTEIN SUBUNIT; UNCLASSIFIED DRUG; UROKINASE; UROKINASE TYPE PLASMINOGEN ACTIVATOR RECEPTOR; CD11B ANTIGEN; CELL SURFACE RECEPTOR; GLYCOSYLPHOSPHATIDYLINOSITOL; INTEGRIN; UROKINASE TYPE PLASMINOGEN ACTIVATOR RECEPTORS; UROKINASE-TYPE PLASMINOGEN ACTIVATOR RECEPTORS; VERY LATE ACTIVATION ANTIGEN 5;

ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CYTOPLASM; DISULFIDE BOND; FLUORESCENCE RESONANCE ENERGY TRANSFER; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN INTERACTION; CELL MEMBRANE; CELL STRAIN K 562; CHEMISTRY; CONFORMATION; HUMAN; METABOLISM; PROTEIN TERTIARY STRUCTURE; SIGNAL TRANSDUCTION;

ANTIBODIES, MONOCLONAL; CELL MEMBRANE; CYTOPLASM; FLUORESCENCE RESONANCE ENERGY TRANSFER; GLYCOSYLPHOSPHATIDYLINOSITOLS; HUMANS; INTEGRIN ALPHA5BETA1; INTEGRINS; K562 CELLS; MACROPHAGE-1 ANTIGEN; MOLECULAR CONFORMATION; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION;

EID: 54449096395     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M802311200     Document Type: Article

References (68)

1. Plow, E. F., and Zhang, L. (1997) J. Clin. Investig. 99, 1145-1146
2. Ehlers, M. R. (2000) Microbes Infect. 2, 289-294
3. Xiong, J. P., Stehle, T., Zhang, R., Joachimiak, A., Frech, M., Goodman, S. L., and Arnaout, M. A. (2002) Science 296, 151-155
4. Plow, E. F., Haas, T. A., Zhang, L., Loftus, J., and Smith, J. W. (2000) J. Biol. Chem. 275, 21785-21788
5. Forsyth, C. B., Plow, E. F., and Zhang, L. (1998) J. Immunol. 161, 6198-6205
6. Cywes, C., Godenir, N. L., Hoppe, H. C., Scholle, R. R., Steyn, L. M., Kirsch, R. E., and Ehlers, M. R. (1996) Infect. Immun. 64, 5373-5383
7. Davis, G. E. (1992) Exp. Cell Res. 200, 242-252
8. Rosenkranz, A. R., Coxon, A., Maurer, M., Gurish, M. F., Austen, K. F., Friend, D. S., Galli, S. J., and Mayadas, T. N. (1998) J. Immunol. 161, 6463-6467
9. Andrew, D. P., Spellberg, J. P., Takimoto, H., Schmits, R., Mak, T. W., and Zukowski, M. M. (1998) Eur. J. Immunol. 28, 1959-1969
10. Lu, H., Smith, C. W., Perrard, J., Bullard, D., Tang, L., Shappell, S. B., Entman, M. L., Beaudet, A. L., and Ballantyne, C. M. (1997) J. Clin. Investig. 99, 1340-1350
11. Behrens, E. M., Sriram, U., Shivers, D. K., Gallucci, M., Ma, Z., Finkel, T. H., and Gallucci, S. (2007) J. Immunol. 178, 6268-6279
12. Skoberne, M., Somersan, S., Almodovar, W., Truong, T., Petrova, K., Henson, P. M., and Bhardwaj, N. (2006) Blood 108, 947-955
13. Annenkov, A., Ortlepp, S., and Hogg, N. (1996) Eur. J. Immunol. 26, 207-212
14. Bohuslav, J., Horejsi, V., Hansmann, C., Stockl, J., Weidle, U. H., Majdic, O., Bartke, I., Knapp, W., and Stockinger, H. (1995) J. Exp. Med. 181, 1381-1390
15. Spijkers, P. P., da Costa Martins, P., Westein, E., Gahmberg, C. G., Zwaginga, J. J., and Lenting, P. J. (2005) Blood 105, 170-177
16. Zhou, M., Todd, R. F., III, van de Winkel, J. G., and Petty, H. R. (1993) J. Immunol. 150, 3030-3041
17. Simon, D. I., Rao, N. K., Xu, H., Wei, Y., Majdic, O., Ronne, E., Kobzik, L., and Chapman, H. A. (1996) Blood 88, 3185-3194
18. Pluskota, E., Soloviev, D. A., and Plow, E. F. (2003) Blood 101, 1582-1590
19. Xue, W., Mizukami, I., Todd, R. F., III, and Petty, H. R. (1997) Cancer Res. 57, 1682-1689
20. Tarui, T., Mazar, A. P., Cines, D. B., and Takada, Y. (2001) J. Biol. Chem. 276, 3983-3990
21. Blasi, F., and Carmeliet, P. (2002) Nat. Rev. Mol. Cell Biol. 3, 932-943
22. Wei, Y., Czekay, R. P., Robillard, L., Kugler, M. C., Zhang, F., Kim, K. K., Xiong, J. P., Humphries, M. J., and Chapman, H. A. (2005) J. Cell Biol. 168, 501-511
23. Wei, Y., Tang, C. H., Kim, Y., Robillard, L., Zhang, F., Kugler, M. C., and Chapman, H. A. (2007) J. Biol. Chem. 282, 3929-3939
24. Luo, B. H., Carman, C. V., and Springer, T. A. (2007) Annu. Rev. Immunol. 25, 619-647
25. Arnaout, M. A., Goodman, S. L., and Xiong, J. P. (2007) Curr. Opin. Cell Biol. 19, 495-507
26. Simon, D. I., Wei, Y., Zhang, L., Rao, N. K., Xu, H., Chen, Z., Liu, Q., Rosenberg, S., and Chapman, H. A. (2000) J. Biol. Chem. 275, 10228-10234
27. Llinas, P., Le Du, M. H., Gardsvoll, H., Dano, K., Ploug, M., Gilquin, B., Stura, E. A., and Menez, A. (2005) EMBO J. 24, 1655-1663
28. Arnaout, M. A., Mahalingam, B., and Xiong, J. P. (2005) Annu. Rev. Cell Dev. Biol. 21, 381-410
29. Zhu, J., Carman, C. V., Kim, M., Shimaoka, M., Springer, T. A., and Luo, B. H. (2007) Blood 110, 2475-2483
30. Uciechowski, P., and von Schimidt, R. E. (1989) Cluster Report CD11, Oxford University Press, Oxford
31. Shaw, J. M., Al-Shamkhani, A., Boxer, L. A., Buckley, C. D., Dodds, A. W., Klein, N., Nolan, S. M., Roberts, I., Roos, D., Scarth, S. L., Simmons, D. L., Tan, S. M., and Law, S. K. (2001) Clin. Exp. Immunol. 126, 311-318
32. Andrew, D., Shock, A., Ball, E., Ortlepp, S., Bell, J., and Robinson, M. (1993) Eur. J. Immunol. 23, 2217-2222
33. Stephens, P., Romer, J. T., Spitali, M., Shock, A., Ortlepp, S., Figdor, C. G., and Robinson, M. K. (1995) Cell Adhes. Commun. 3, 375-384
34. Beglova, N., Blacklow, S. C., Takagi, J., and Springer, T. A. (2002) Nat. Struct. Biol. 9, 282-287
35. Tang, M. L., Kong, L. S., Law, S. K., and Tan, S. M. (2006) Biochem. Biophys. Res. Commun. 348, 1184-1193
36. Tang, R. H., Tng, E., Law, S. K., and Tan, S. M. (2005) J. Biol. Chem. 280, 29208-29216
37. Barclay, A. N., Brown, M. H., Law, S. K., McKnight, A. J., Tomlinson, M. G., and van der Merwe, P. A. (1997) The Leukocyte Antigen Facts Book, 2nd Ed., pp. 158-160, 177-178, and 347-348, Academic Press, Inc., London, UK
38. Kim, M., Carman, C. V., and Springer, T. A. (2003) Science 301, 1720-1725
39. Vararattanavech, A., Tang, M. L., Li, H. Y., Wong, C. H., Law, S. K., Torres, J., and Tan, S. M. (2007) Biochem. J. 410, 495-502
40. Xue, W., Kindzelskii, A. L., Todd, R. F., III, and Petty, H. R. (1994) J. Immunol. 152, 4630-4640
41. Nishida, N., Xie, C., Shimaoka, M., Cheng, Y., Walz, T., and Springer, T. A. (2006) Immunity 25, 583-594
42. Mould, A. P., Barton, S. J., Askari, J. A., McEwan, P. A., Buckley, P. A., Craig, S. E., and Humphries, M. J. (2003) J. Biol. Chem. 278, 17028-17035
43. Xiao, T., Takagi, J., Coller, B. S., Wang, J. H., and Springer, T. A. (2004) Nature 432, 59-67
44. Lu, C., Ferzly, M., Takagi, J., and Springer, T. A. (2001) J. Immunol. 166, 5629-5637
45. Altieri, D. C. (1991) J. Immunol. 147, 1891-1898
46. Cheng, M., Foo, S. Y., Shi, M. L., Tang, R. H., Kong, L. S., Law, S. K., and Tan, S. M. (2007) J. Biol. Chem. 282, 18225-18232
47. Violette, S. M., Rusche, J. R., Purdy, S. R., Boyd, J. G., Cos, J., and Silver, S. (1995) J. Immunol. 155, 3092-3101
48. Fu, G., Yang, H. Y., Wang, C., Zhang, F., You, Z. D., Wang, G. Y., He, C., Chen, Y. Z., and Xu, Z. Z. (2006) Biochem. Biophys. Res. Commun. 346, 986-991
49. Lau, T. L., Dua, V., and Ulmer, T. S. (2008) J. Biol. Chem. 283, 16162-16168
50. Lau, T. L., Partridge, A. W., Ginsberg, M. H., and Ulmer, T. S. (2008) Biochemistry 47, 4008-4016
51. Cao, D., Mizukami, I. F., Garni-Wagner, B. A., Kindzelskii, A. L., Todd, R. F., III, Boxer, L. A., and Petty, H. R. (1995) J. Immunol. 154, 1817-1829
52. Juffermans, N. P., Dekkers, P. E., Verbon, A., Speelman, P., van Deventer, S. J., and van der Poll, T. (2001) Infect. Immun. 69, 5182-5185
53. Luo, B. H., Springer, T. A., and Takagi, J. (2004) PLoS Biol. 2, e153
54. Lim, J., Wiedemann, A., Tzircotis, G., Monkley, S. J., Critchley, D. R., and Caron, E. (2007) Mol. Biol. Cell 18, 976-985
55. Pluskota, E., Soloviev, D. A., Bdeir, K., Cines, D. B., and Plow, E. F. (2004) J. Biol. Chem. 279, 18063-18072
56. Zhang, H., Colman, R. W., and Sheng, N. (2003) Inflamm Res. 52, 86-93
57. Gyetko, M. R., Aizenberg, D., and Mayo-Bond, L. (2004) J. Leukocyte Biol. 76, 648-656
58. Gyetko, M. R., Sud, S., Kendall, T., Fuller, J. A., Newstead, M. W., and Standiford, T. J. (2000) J. Immunol. 165, 1513-1519
59. Luque, A., Gomez, M., Puzon, W., Takada, Y., Sanchez-Madrid, F., and Cabanas, C. (1996) J. Biol. Chem. 271, 11067-11075
60. Bazzoni, G., Shih, D. T., Buck, C. A., and Hemler, M. E. (1995) J. Biol. Chem. 270, 25570-25577
61. Takagi, J., Strokovich, K., Springer, T. A., and Walz, T. (2003) EMBO J. 22, 4607-4615
62. Cunningham, O., Andolfo, A., Santovito, M. L., Iuzzolino, L., Blasi, F., and Sidenius, N. (2003) EMBO J. 22, 5994-6003
63. Adair, B. D., Xiong, J. P., Maddock, C., Goodman, S. L., Arnaout, M. A., and Yeager, M. (2005) J. Cell Biol. 168, 1109-1118
64. Chigaev, A., Blenc, A. M., Braaten, J. V., Kumaraswamy, N., Kepley, C. L., Andrews, R. P., Oliver, J. M., Edwards, B. S., Prossnitz, E. R., Larson, R. S., and Sklar, L. A. (2001) J. Biol. Chem. 276, 48670-48678
65. Larson, R. S., Davis, T., Bologa, C., Semenuk, G., Vijayan, S., Li, Y., Oprea, T., Chigaev, A., Buranda, T., Wagner, C. R., and Sklar, L. A. (2005) Biochemistry 44, 4322-4331
66. Huai, Q., Mazar, A. P., Kuo, A., Parry, G. C., Shaw, D. E., Callahan, J., Li, Y., Yuan, C., Bian, C., Chen, L., Furie, B., Furie, B. C., Cines, D. B., and Huang, M. (2006) Science 311, 656-659
67. Baldwin, E. T., Sarver, R. W., Bryant, G. L., Jr., Curry, K. A., Fairbanks, M. B., Finzel, B. C., Garlick, R. L., Heinrikson, R. L., Horton, N. C., Kelley, L. L., Mildner, A. M., Moon, J. B., Mott, J. E., Mutchler, V. T., Tomich, C. S., Watenpaugh, K. D., and Wiley, V. H. (1998) Structure 6, 923-935
68. Shi, M., Foo, S. Y., Tan, S. M., Mitchell, E. P., Law, S. K., and Lescar, J. (2007) J. Biol. Chem. 282, 30198-30206