메뉴 건너뛰기




Volumn 4, Issue 5, 2004, Pages 795-802

Clinical management of medulloblastoma in adults

Author keywords

Adults; Brain tumor; Chemotherapy; Clinical trials; Medulloblastoma; Prognostic factors; Radiation therapy

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; CYCLOPHOSPHAMIDE; CYTARABINE; ETOPOSIDE; IFOSFAMIDE; LOMUSTINE; PREDNISONE; THIOTEPA; VINCRISTINE;

EID: 5444273591     PISSN: 14737140     EISSN: None     Source Type: Journal    
DOI: 10.1586/14737140.4.5.795     Document Type: Review
Times cited : (10)

References (43)
  • 3
  • 4
    • 0037362950 scopus 로고    scopus 로고
    • Should adolescents with acute lymphoblastic leukemia be treated as old children or young adults? Comparison of the French FRALLE-93 and LALA-94 trials
    • Boissel N, Auclerc MF, Lhéritier V et al. Should adolescents with acute lymphoblastic leukemia be treated as old children or young adults? Comparison of the French FRALLE-93 and LALA-94 trials. J. Clin. Oncol. 21, 774-780 (2003).
    • (2003) J. Clin. Oncol. , vol.21 , pp. 774-780
    • Boissel, N.1    Auclerc, M.F.2    Lhéritier, V.3
  • 5
    • 0037364547 scopus 로고    scopus 로고
    • Differences in outcome in adolescents with acute lymphoblastic leukemia: A consequence of better regimens? Better doctors? Both?
    • Schiffer CA. Differences in outcome in adolescents with acute lymphoblastic leukemia: a consequence of better regimens? Better doctors? Both? J. Clin. Oncol. 21, 760-761 (2003).
    • (2003) J. Clin. Oncol. , vol.21 , pp. 760-761
    • Schiffer, C.A.1
  • 6
    • 0034491135 scopus 로고    scopus 로고
    • Correlation of neurosurgical subspecialization with outcomes in children with malignant brain rumors
    • Albright AL, Sposto R, Holmes E et al. Correlation of neurosurgical subspecialization with outcomes in children with malignant brain rumors. Neurosurgery 47, 879-885 (2000).
    • (2000) Neurosurgery , vol.47 , pp. 879-885
    • Albright, A.L.1    Sposto, R.2    Holmes, E.3
  • 7
    • 0033050817 scopus 로고    scopus 로고
    • Metastasis stage, adjuvant treatment, and residual tumor are prognostic factors for medulloblastoma in children: Conclusions from the Children's Cancer Group 921 randomized Phase III study
    • Zeltzer PM, Boyett JM, Finlay JL et al. Metastasis stage, adjuvant treatment, and residual tumor are prognostic factors for medulloblastoma in children: conclusions from the Children's Cancer Group 921 randomized Phase III study. J. Clin. Oncol. 17, 832-845 (1999 ).
    • (1999) J. Clin. Oncol. , vol.17 , pp. 832-845
    • Zeltzer, P.M.1    Boyett, J.M.2    Finlay, J.L.3
  • 8
    • 0342614892 scopus 로고    scopus 로고
    • Postoperative neoadjuvant chemotherapy before radiotherapy as compared to immediate radiotherapy followed by maintenance chemotherapy in the treatment of medulloblastoma in childhood: Results of the German prospective randomized trial HIT '91
    • Kortmann RD, Kühl J, Timmermann B et al. Postoperative neoadjuvant chemotherapy before radiotherapy as compared to immediate radiotherapy followed by maintenance chemotherapy in the treatment of medulloblastoma in childhood: results of the German prospective randomized trial HIT '91. Int. J. Radiat. Oncol. Biol. Phys. 46, 269-279 (2000).
    • (2000) Int. J. Radiat. Oncol. Biol. Phys. , vol.46 , pp. 269-279
    • Kortmann, R.D.1    Kühl, J.2    Timmermann, B.3
  • 9
    • 0037842140 scopus 로고    scopus 로고
    • Results of a randomized study of preradiation chemotherapy versus radiotherapy alone for nonmetastatic medulloblastoma the International Society of Paediatric Oncology/United Kingdom Children's Cancer Study Group PNET-3 study
    • Taylor RE, Bailey CC, Robinson K et al. Results of a randomized study of preradiation chemotherapy versus radiotherapy alone for nonmetastatic medulloblastoma the International Society of Paediatric Oncology/United Kingdom Children's Cancer Study Group PNET-3 study. J. Clin. Oncol. 21, 1581-1591 (2003).
    • (2003) J. Clin. Oncol. , vol.21 , pp. 1581-1591
    • Taylor, R.E.1    Bailey, C.C.2    Robinson, K.3
  • 10
    • 0033902778 scopus 로고    scopus 로고
    • Low-stage medulloblastoma: Final analysis of trial comparing standard-dose with reduced-dose neuraxis irradiation
    • Thomas PRM, Deutsch M, Kepner JL et al. Low-stage medulloblastoma: final analysis of trial comparing standard-dose with reduced-dose neuraxis irradiation. J. Clin. Oncol. 18, 3004-3011 (2000).
    • (2000) J. Clin. Oncol. , vol.18 , pp. 3004-3011
    • Thomas, P.R.M.1    Deutsch, M.2    Kepner, J.L.3
  • 11
    • 0033056823 scopus 로고    scopus 로고
    • Treatment of children with medulloblastomas with reduced-dose craniospinal radiation therapy and adjuvant chemotherapy: A Children's Cancer Group study
    • Packer RJ, Goldwein J, Nicholson HS et al. Treatment of children with medulloblastomas with reduced-dose craniospinal radiation therapy and adjuvant chemotherapy: a Children's Cancer Group study. J. Clin. Oncol. 17, 2127-2136 (1999).
    • (1999) J. Clin. Oncol. , vol.17 , pp. 2127-2136
    • Packer, R.J.1    Goldwein, J.2    Nicholson, H.S.3
  • 12
    • 5444249148 scopus 로고    scopus 로고
    • Preliminary report of A9961: A Phase III randomized study of craniospinal radiotherapy (CSRT) followed by one of two adjuvant chemotherapy regimens (CCNU, CPDD, VCR or CPM, CPDD, VCR) in children with newly diagnosed average-risk medulloblastoma (MB)
    • (Abstract Ther. 61)
    • Packer R, Gajjar A, Vezina G et al. Preliminary report of A9961: a Phase III randomized study of craniospinal radiotherapy (CSRT) followed by one of two adjuvant chemotherapy regimens (CCNU, CPDD, VCR or CPM, CPDD, VCR) in children with newly diagnosed average-risk medulloblastoma (MB). Proc. Int. Symp. Pediatr. Neurooncol. (2004) (Abstract Ther. 61).
    • (2004) Proc. Int. Symp. Pediatr. Neurooncol.
    • Packer, R.1    Gajjar, A.2    Vezina, G.3
  • 14
    • 1842509920 scopus 로고    scopus 로고
    • Biologic risk stratification of medulloblastoma: The real time is now
    • Fisher PG, Burger PC, Eberhart CG. Biologic risk stratification of medulloblastoma: the real time is now. J. Clin. Oncol. 22, 971-974 (2004).
    • (2004) J. Clin. Oncol. , vol.22 , pp. 971-974
    • Fisher, P.G.1    Burger, P.C.2    Eberhart, C.G.3
  • 15
    • 1642307767 scopus 로고    scopus 로고
    • Medulloblastoma: Signalling a change in treatment
    • Gilbertson RJ. Medulloblastoma: signalling a change in treatment. Lancet Oncol. 5, 209-218 (2004).
    • (2004) Lancet Oncol. , vol.5 , pp. 209-218
    • Gilbertson, R.J.1
  • 16
    • 0041411499 scopus 로고    scopus 로고
    • Patterns of failure using a conformal radiation therapy tumor bed boost for medulloblastoma
    • Wolden SL, Dunkel IJ, Souweidane MM et al. Patterns of failure using a conformal radiation therapy tumor bed boost for medulloblastoma. J. Clin. Oncol. 21, 3079-3083 (2003).
    • (2003) J. Clin. Oncol. , vol.21 , pp. 3079-3083
    • Wolden, S.L.1    Dunkel, I.J.2    Souweidane, M.M.3
  • 17
    • 0028102963 scopus 로고
    • Multivariate analysis of prognostic factors in adult patients with medulloblastoma. Retrospective study of 156 patients
    • Carrie C, Lasset C, Alapetite C et al. Multivariate analysis of prognostic factors in adult patients with medulloblastoma. Retrospective study of 156 patients. Cancer 74, 2352-2360 (1994).
    • (1994) Cancer , vol.74 , pp. 2352-2360
    • Carrie, C.1    Lasset, C.2    Alapetite, C.3
  • 20
    • 0034518223 scopus 로고    scopus 로고
    • Adult medulloblastoma: Prognostic factors and patterns of relapse
    • Chan AW, Tarbell NJ, Black PM et al. Adult medulloblastoma: prognostic factors and patterns of relapse. Neurosurgery 47, 623-632 (2000).
    • (2000) Neurosurgery , vol.47 , pp. 623-632
    • Chan, A.W.1    Tarbell, N.J.2    Black, P.M.3
  • 21
    • 0014619880 scopus 로고
    • An operative staging system and a megavoltage radiotherapeutic technique for cerebellar medulloblastomas
    • Chang CH, Housepian EM, Hebert C Jr. An operative staging system and a megavoltage radiotherapeutic technique for cerebellar medulloblastomas. Radiology 93, 1351-1359 (1969).
    • (1969) Radiology , vol.93 , pp. 1351-1359
    • Chang, C.H.1    Housepian, E.M.2    Hebert Jr., C.3
  • 23
    • 0035407296 scopus 로고    scopus 로고
    • Survival and recurrence factors in adult medulloblastoma: The MD Anderson Cancer Center experience from 1978 to 1998
    • Kunschner LJ, Kuttesch J, Hess K, Yung WKA. Survival and recurrence factors in adult medulloblastoma: the MD Anderson Cancer Center experience from 1978 to 1998. Neurooncology 3, 167-173 (2001).
    • (2001) Neurooncology , vol.3 , pp. 167-173
    • Kunschner, L.J.1    Kuttesch, J.2    Hess, K.3    Yung, W.K.A.4
  • 24
    • 0036835447 scopus 로고    scopus 로고
    • Medulloblastoma in adults: Treatment results and prognostic factors
    • Abacioglu U, Uzel O, Sengoz M et al. Medulloblastoma in adults: treatment results and prognostic factors. Int. J. Radiat. Oncol. Biol. Phys. 54, 855-860 (2002).
    • (2002) Int. J. Radiat. Oncol. Biol. Phys. , vol.54 , pp. 855-860
    • Abacioglu, U.1    Uzel, O.2    Sengoz, M.3
  • 27
    • 0029620728 scopus 로고
    • Prognostic factors in adult medulloblastoma. A clinico-pathologic study
    • Giordana MT, Cavalla P, Chic, A et al. Prognostic factors in adult medulloblastoma. A clinico-pathologic study. Tumori 81, 338-346 (1995).
    • (1995) Tumori , vol.81 , pp. 338-346
    • Giordana, M.T.1    Cavalla, P.2    Chic, A.3
  • 28
    • 0036679244 scopus 로고    scopus 로고
    • Are childhood and adult medulloblastomas different? A comparative study of clinicopathological features, proliferation index and apoptotic index
    • Sarkar C, Pramanik P, Karak AK et al. Are childhood and adult medulloblastomas different? A comparative study of clinicopathological features, proliferation index and apoptotic index. J. Neurooncol. 59, 49-61 (2002).
    • (2002) J. Neurooncol. , vol.59 , pp. 49-61
    • Sarkar, C.1    Pramanik, P.2    Karak, A.K.3
  • 29
    • 0036205588 scopus 로고    scopus 로고
    • MDM2 overexpression is associated with short survival in adults with medulloblastoma
    • Giordana MT, Duo D, Gasverde S et al. MDM2 overexpression is associated with short survival in adults with medulloblastoma. Neurooncology 4, 115-122 (2002).
    • (2002) Neurooncology , vol.4 , pp. 115-122
    • Giordana, M.T.1    Duo, D.2    Gasverde, S.3
  • 30
    • 0036856486 scopus 로고    scopus 로고
    • Possible benefits of high-dose chemotherapy and autologous stem cell transplantation for adults with recurrent medulloblastoma
    • Zia MI, Forsyth P, Chaudry A et al. Possible benefits of high-dose chemotherapy and autologous stem cell transplantation for adults with recurrent medulloblastoma. Bone Marrow Transplant. 30, 565-569 (2002).
    • (2002) Bone Marrow Transplant. , vol.30 , pp. 565-569
    • Zia, M.I.1    Forsyth, P.2    Chaudry, A.3
  • 31
    • 0033379173 scopus 로고    scopus 로고
    • High dose chemotherapy with hematopoietic stem cell transplantation in adults with bone marrow relapse of medulloblastoma: Report of two cases
    • Millot F, Delval O, Giraud C et al. High dose chemotherapy with hematopoietic stem cell transplantation in adults with bone marrow relapse of medulloblastoma: report of two cases. Bone Marrow Transplant. 24, 1347-1349 (1999).
    • (1999) Bone Marrow Transplant. , vol.24 , pp. 1347-1349
    • Millot, F.1    Delval, O.2    Giraud, C.3
  • 32
    • 0032842530 scopus 로고    scopus 로고
    • Impact of targeting deviations on outcome in medulloblastoma: Study of the French Society of Pediatric Oncology (SFOP)
    • Carrie C, Hoffstetter S, Gomez F et al. Impact of targeting deviations on outcome in medulloblastoma: study of the French Society of Pediatric Oncology (SFOP). Int. J. Radiat. Oncol. Biol. Phys. 45, 435-439 (1999).
    • (1999) Int. J. Radiat. Oncol. Biol. Phys. , vol.45 , pp. 435-439
    • Carrie, C.1    Hoffstetter, S.2    Gomez, F.3
  • 33
    • 0033063502 scopus 로고    scopus 로고
    • Comparison of lumbar and shunt cerebrospinal fluid specimens for cytologic detection of leptomeningeal disease in pediatric patients with brain tumors
    • Gajjar A, Fouladi M, Walter AW et al. Comparison of lumbar and shunt cerebrospinal fluid specimens for cytologic detection of leptomeningeal disease in pediatric patients with brain tumors. J. Clin. Oncol. 17, 1825-1828 (1999).
    • (1999) J. Clin. Oncol. , vol.17 , pp. 1825-1828
    • Gajjar, A.1    Fouladi, M.2    Walter, A.W.3
  • 34
    • 0032886935 scopus 로고    scopus 로고
    • Comparison of CSF cytology and spinal magnetic resonance imaging in the detection of leptomeningeal disease in pediatric medulloblastoma or primitive neuroectodermal tumor
    • Fouladi M, Gajjar A, Boyett JM et al. Comparison of CSF cytology and spinal magnetic resonance imaging in the detection of leptomeningeal disease in pediatric medulloblastoma or primitive neuroectodermal tumor. J. Clin. Oncol. 17, 3234-3237 (1999).
    • (1999) J. Clin. Oncol. , vol.17 , pp. 3234-3237
    • Fouladi, M.1    Gajjar, A.2    Boyett, J.M.3
  • 35
    • 0037336192 scopus 로고    scopus 로고
    • Medulloblastomas with systemic metastases: Evaluation of tumor histopathology and clinical behavior in 23 patients
    • Eberhart CG, Cohen KJ, Tihan T et al. Medulloblastomas with systemic metastases: evaluation of tumor histopathology and clinical behavior in 23 patients. J. Pediatr. Hematol. Oncol. 25, 198-203 (2003).
    • (2003) J. Pediatr. Hematol. Oncol. , vol.25 , pp. 198-203
    • Eberhart, C.G.1    Cohen, K.J.2    Tihan, T.3
  • 36
    • 0033791188 scopus 로고    scopus 로고
    • Large cell/anaplastic medulloblastomas: A Pediatric Oncology Group Study
    • Brown HG, Kepner JL, Perlman EJ et al. Large cell/anaplastic medulloblastomas: a Pediatric Oncology Group Study. J. Neuropathol. Exp. Neurol. 59, 857-65 (2000).
    • (2000) J. Neuropathol. Exp. Neurol. , vol.59 , pp. 857-865
    • Brown, H.G.1    Kepner, J.L.2    Perlman, E.J.3
  • 37
    • 0037080303 scopus 로고    scopus 로고
    • Histopathologic grading of medulloblastoma: A Pediatric Oncology Group Study
    • Eberhart CG, Kepner JL, Goldthwaite PT et al. Histopathologic grading of medulloblastoma: a Pediatric Oncology Group Study. Cancer 94, 552-560 (2002).
    • (2002) Cancer , vol.94 , pp. 552-560
    • Eberhart, C.G.1    Kepner, J.L.2    Goldthwaite, P.T.3
  • 38
    • 0036293474 scopus 로고    scopus 로고
    • Radiotherapy for medulloblastoma in children: A perspective on current international clinical research efforts
    • Freeman CR, Taylor RE, Kortman RD, Carrie C. Radiotherapy for medulloblastoma in children: a perspective on current international clinical research efforts. Med. Pediatr. Oncol. 39, 99-108 (2002).
    • (2002) Med. Pediatr. Oncol. , vol.39 , pp. 99-108
    • Freeman, C.R.1    Taylor, R.E.2    Kortman, R.D.3    Carrie, C.4
  • 39
    • 3042796790 scopus 로고    scopus 로고
    • A multi-institution prospective trial of reduced dose craniospinal irradiation (23.4 Gy) followed by conformal posterior fossa (36 Gy) and primary site irradiation (55.8 Gy) and dose-intensive chemotherapy for average-risk medulloblastoma
    • Merchant TE, Kun LE, Krasin MJ et al. A multi-institution prospective trial of reduced dose craniospinal irradiation (23.4 Gy) followed by conformal posterior fossa (36 Gy) and primary site irradiation (55.8 Gy) and dose-intensive chemotherapy for average-risk medulloblastoma. Int. J. Radiat. Oncol. Biol. Phys. 57(Suppl.), S194-S195 (2003).
    • (2003) Int. J. Radiat. Oncol. Biol. Phys. , vol.57 , Issue.SUPPL.
    • Merchant, T.E.1    Kun, L.E.2    Krasin, M.J.3
  • 40
    • 3042710402 scopus 로고    scopus 로고
    • Conformal radiotherapy, reduced boost volume, hyperfractionated radiotherapy and on-line quality control in standard risk medulloblastoma without chemotherapy. Results of the French M-SFOP 98 protocol
    • Carrie C, Muracciole X, Gomez F et al. Conformal radiotherapy, reduced boost volume, hyperfractionated radiotherapy and on-line quality control in standard risk medulloblastoma without chemotherapy. Results of the French M-SFOP 98 protocol. Int. J. Radiat. Oncol. Biol. Phys. 57(Suppl.), S195 (2003).
    • (2003) Int. J. Radiat. Oncol. Biol. Phys. , vol.57 , Issue.SUPPL.
    • Carrie, C.1    Muracciole, X.2    Gomez, F.3
  • 41
    • 5444222885 scopus 로고    scopus 로고
    • Medulloblastoma in the second decade of life: A specific group with respect to toxicity and management
    • A Canadian Paediatric Brain Tumor Consortium Study. (Abstract Ther. 77)
    • Tabori U, Hukin J, Crooks B et al. Medulloblastoma in the second decade of life: a specific group with respect to toxicity and management. A Canadian Paediatric Brain Tumor Consortium Study. Proc. Int. Symp. Pediatr. Neurooncol. (2004) (Abstract Ther. 77).
    • (2004) Proc. Int. Symp. Pediatr. Neurooncol.
    • Tabori, U.1    Hukin, J.2    Crooks, B.3
  • 42
    • 1842509921 scopus 로고    scopus 로고
    • Combining gene expression profiles and clinical parameters for risk stratification in medulloblastomas
    • Fernandez-Teijeiro A, Betensky RA, Sturla LM et al. Combining gene expression profiles and clinical parameters for risk stratification in medulloblastomas. J. Clin. Oncol. 22, 1-5 (2004 ).
    • (2004) J. Clin. Oncol. , vol.22 , pp. 1-5
    • Fernandez-Teijeiro, A.1    Betensky, R.A.2    Sturla, L.M.3
  • 43
    • 1842614251 scopus 로고    scopus 로고
    • Clinical, histopathologic, and molecular markers of prognosis: Toward a new disease risk stratification system for medulloblastoma
    • Gajjar A, Hernan F, Kocak M et al. Clinical, histopathologic, and molecular markers of prognosis: toward a new disease risk stratification system for medulloblastoma. J. Clin. Oncol. 22, 984-993 (2004).
    • (2004) J. Clin. Oncol. , vol.22 , pp. 984-993
    • Gajjar, A.1    Hernan, F.2    Kocak, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.