A novel SCN5A mutation manifests as a malignant form of long QT syndrome with perinatal onset of tachycardia/bradycardia

Cardiovascular Research

Volumn 64, Issue 2, 2004, Pages 268-278

  Chang, Chien Chih ^a,d   Acharfi, Said ^b   Wu, Mei Hwan ^a   Chiang, Fu Tien ^a   Wang, Jou Kou ^a   Sung, Tseng Chen ^c   Chahine, Mohamed ^b  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b LAVAL UNIVERSITY   (Canada)

^c SHIN KONG WU HO SU MEMORIAL HOSPITAL   (Taiwan)

^d MIN SHENG GENERAL HOSPITAL   (Taiwan)

Author keywords

Atrioventricular block; Congenital long QT syndrome; Fetus; Nav1.5; Newborn; SCN5A; Sodium channels

Indexed keywords

LIDOCAINE; METHIONINE; MEXILETINE; SODIUM CHANNEL; TETRODOTOXIN; VALINE;

AMINO ACID SUBSTITUTION; ARTICLE; ATRIOVENTRICULAR BLOCK; BRADYCARDIA; CODON; DNA SEQUENCE; GENE EXPRESSION; GENE IDENTIFICATION; GENE MUTATION; HEART VENTRICLE TACHYCARDIA; HETEROZYGOTE; HUMAN; MAMMAL CELL; MUTATIONAL ANALYSIS; NEWBORN; PERINATAL PERIOD; PRIORITY JOURNAL; QT PROLONGATION; SINUS NODE MEMBRANE POTENTIAL; SITE DIRECTED MUTAGENESIS; STEADY STATE;

BRADYCARDIA; CELL LINE; DNA MUTATIONAL ANALYSIS; FEMALE; HUMANS; INFANT, NEWBORN; LIDOCAINE; LONG QT SYNDROME; MALE; MUTATION; MYOCARDIUM; PATCH-CLAMP TECHNIQUES; SEQUENCE ANALYSIS, DNA; SODIUM CHANNELS; TACHYCARDIA, VENTRICULAR; TETRODOTOXIN; TRANSFECTION;

EID: 5444259262     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cardiores.2004.07.007     Document Type: Article

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