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Volumn 35, Issue 10, 2004, Pages 1260-1265

PTEN- mutations do not cause nuclear β-catenin accumulation in endometrial carcinomas

Author keywords

catenin expression; CTNNB1; endometrial carcinoma; FIGO; ILK; integrin linked kinase; International Federation of Gynecology and Obstetrics; mutations; PCR; polymerase chain reaction; PTEN; single strand conformation polymorphism; SSCP

Indexed keywords

BETA CATENIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE;

EID: 5444244379     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humpath.2004.06.007     Document Type: Article
Times cited : (12)

References (24)
  • 1
    • 0034950673 scopus 로고    scopus 로고
    • Molecular pathology of endometrial hyperplasia and carcinoma
    • Matias-Guiu X., Catasus L., Bussaglia E., et al. Molecular pathology of endometrial hyperplasia and carcinoma. Hum Pathol. 32:2001;569-577
    • (2001) Hum Pathol , vol.32 , pp. 569-577
    • Matias-Guiu, X.1    Catasus, L.2    Bussaglia, E.3
  • 2
    • 0036569795 scopus 로고    scopus 로고
    • Distinct sets of gene alterations in endometrial carcinoma implicate alternate modes of tumourigenesis
    • Koul A., Willen R., Bendahl P.O., et al. Distinct sets of gene alterations in endometrial carcinoma implicate alternate modes of tumourigenesis. Cancer. 94:2002;2369-2379
    • (2002) Cancer , vol.94 , pp. 2369-2379
    • Koul, A.1    Willen, R.2    Bendahl, P.O.3
  • 3
    • 84984777123 scopus 로고    scopus 로고
    • PTEN1 is frequently mutated in primary endometrial carcinomas
    • Kong D., Suzuki A., Zou T.T., et al. PTEN1 is frequently mutated in primary endometrial carcinomas. Nat Genet. 17:1997;143-144
    • (1997) Nat Genet , vol.17 , pp. 143-144
    • Kong, D.1    Suzuki, A.2    Zou, T.T.3
  • 4
    • 0032529234 scopus 로고    scopus 로고
    • Beta-catenin mutation in carcinoma of the uterine endometrium
    • Fukuchi T., Sakamoto M., Tsuda H., et al. Beta-catenin mutation in carcinoma of the uterine endometrium. Cancer Res. 58:1998;3526-3528
    • (1998) Cancer Res , vol.58 , pp. 3526-3528
    • Fukuchi, T.1    Sakamoto, M.2    Tsuda, H.3
  • 5
    • 0031004088 scopus 로고    scopus 로고
    • Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome
    • Liaw D., Marsh D.J., Li J., et al. Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome. Nat Genet. 16:1997;64-67
    • (1997) Nat Genet , vol.16 , pp. 64-67
    • Liaw, D.1    Marsh, D.J.2    Li, J.3
  • 6
    • 0031053586 scopus 로고    scopus 로고
    • Regulation of neuronal survival by the serine-threonine protein kinase Akt
    • Dudek H., Datta S.R., Franke T.F., et al. Regulation of neuronal survival by the serine-threonine protein kinase Akt. Science. 275:1997;661-665
    • (1997) Science , vol.275 , pp. 661-665
    • Dudek, H.1    Datta, S.R.2    Franke, T.F.3
  • 7
    • 0032053709 scopus 로고    scopus 로고
    • Mechanisms and consequences of activation of protein kinase B/Akt
    • Downward J. Mechanisms and consequences of activation of protein kinase B/Akt. Curr Opin Cell Biol. 10:1998;262-267
    • (1998) Curr Opin Cell Biol , vol.10 , pp. 262-267
    • Downward, J.1
  • 8
    • 0033520712 scopus 로고    scopus 로고
    • PTEN gene and integrin signaling in cancer
    • Tamura M., Gu J., Tran H., et al. PTEN gene and integrin signaling in cancer. J Natl Cancer Inst. 91:1999;1820-1828
    • (1999) J Natl Cancer Inst , vol.91 , pp. 1820-1828
    • Tamura, M.1    Gu, J.2    Tran, H.3
  • 9
    • 0030944065 scopus 로고    scopus 로고
    • Beta-catenin as oncogene: The smoking gun
    • Peifer M. Beta-catenin as oncogene The smoking gun. Science. 275:1997;1752-1753
    • (1997) Science , vol.275 , pp. 1752-1753
    • Peifer, M.1
  • 10
    • 0030949463 scopus 로고    scopus 로고
    • Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
    • Morin P.J., Sparks A.B., Korinek V., et al. Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Science. 275:1997;1787-1790
    • (1997) Science , vol.275 , pp. 1787-1790
    • Morin, P.J.1    Sparks, A.B.2    Korinek, V.3
  • 11
    • 0029781509 scopus 로고    scopus 로고
    • Functional interaction of beta-catenin with the transcription factor LEF-1
    • Behrens J., von Kries J.P., Kuhl M., et al. Functional interaction of beta-catenin with the transcription factor LEF-1. Nature. 382:1996;638-642
    • (1996) Nature , vol.382 , pp. 638-642
    • Behrens, J.1    Von Kries, J.P.2    Kuhl, M.3
  • 12
    • 0001003110 scopus 로고    scopus 로고
    • XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos
    • Molenaar M., van de Wetering M., Oosterwegel M., et al. XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos. Cell. 86:1996;391-399
    • (1996) Cell , vol.86 , pp. 391-399
    • Molenaar, M.1    Van De Wetering, M.2    Oosterwegel, M.3
  • 13
    • 0035844886 scopus 로고    scopus 로고
    • Tumour suppressor PTEN inhibits nuclear accumulation of beta-catenin and T cell/lymphoid enhancer factor 1-mediated transcriptional activation
    • Persad S., Troussard A.A., McPhee T.R., et al. Tumour suppressor PTEN inhibits nuclear accumulation of beta-catenin and T cell/lymphoid enhancer factor 1-mediated transcriptional activation. J Cell Biol. 153:2001;1161-1174
    • (2001) J Cell Biol , vol.153 , pp. 1161-1174
    • Persad, S.1    Troussard, A.A.2    McPhee, T.R.3
  • 14
    • 7144223432 scopus 로고    scopus 로고
    • PTEN mutations in gliomas and glioneuronal tumours
    • Duerr E.M., Rollbrocker B., Hayashi Y., et al. PTEN mutations in gliomas and glioneuronal tumours. Oncogene. 16:1998;2259-2264
    • (1998) Oncogene , vol.16 , pp. 2259-2264
    • Duerr, E.M.1    Rollbrocker, B.2    Hayashi, Y.3
  • 15
    • 0033001584 scopus 로고    scopus 로고
    • Exclusion of a major role for the PTEN tumour-suppressor gene in breast carcinomas
    • Freihoff D., Kempe A., Beste B., et al. Exclusion of a major role for the PTEN tumour-suppressor gene in breast carcinomas. Br J Cancer. 79:1999;754-758
    • (1999) Br J Cancer , vol.79 , pp. 754-758
    • Freihoff, D.1    Kempe, A.2    Beste, B.3
  • 16
    • 0033556426 scopus 로고    scopus 로고
    • Childhood hepatoblastomas frequently carry a mutated degradation targeting box of the beta-catenin gene
    • Koch A., Denkhaus D., Albrecht S., et al. Childhood hepatoblastomas frequently carry a mutated degradation targeting box of the beta-catenin gene. Cancer Res. 59:1999;269-273
    • (1999) Cancer Res , vol.59 , pp. 269-273
    • Koch, A.1    Denkhaus, D.2    Albrecht, S.3
  • 17
    • 0033579163 scopus 로고    scopus 로고
    • Mutational spectra of PTEN/MMAC1 gene: A tumour suppressor with lipid phosphatase activity
    • Ali I.U., Schriml L.M., Dean M. Mutational spectra of PTEN/MMAC1 gene A tumour suppressor with lipid phosphatase activity. J Natl Cancer Inst. 91:1999;1922-1932
    • (1999) J Natl Cancer Inst , vol.91 , pp. 1922-1932
    • Ali, I.U.1    Schriml, L.M.2    Dean, M.3
  • 18
    • 0032521433 scopus 로고    scopus 로고
    • Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer
    • Sparks A.B., Morin P.J., Vogelstein B., et al. Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer. Cancer Res. 58:1998;1130-1134
    • (1998) Cancer Res , vol.58 , pp. 1130-1134
    • Sparks, A.B.1    Morin, P.J.2    Vogelstein, B.3
  • 19
    • 0030781053 scopus 로고    scopus 로고
    • PTEN/MMAC1 mutations in endometrial cancers
    • Risinger J.I., Hayes A.K., Berchuck A., et al. PTEN/MMAC1 mutations in endometrial cancers. Cancer Res. 57:1997;4736-4738
    • (1997) Cancer Res , vol.57 , pp. 4736-4738
    • Risinger, J.I.1    Hayes, A.K.2    Berchuck, A.3
  • 20
    • 0034616634 scopus 로고    scopus 로고
    • Altered PTEN expression as a diagnostic marker for the earliest endometrial precancers
    • Mutter G.L., Lin M.C., Fitzgerald J.T., et al. Altered PTEN expression as a diagnostic marker for the earliest endometrial precancers. J Natl Cancer Inst. 92:2000;924-930
    • (2000) J Natl Cancer Inst , vol.92 , pp. 924-930
    • Mutter, G.L.1    Lin, M.C.2    Fitzgerald, J.T.3
  • 21
    • 0035153307 scopus 로고    scopus 로고
    • Beta-catenin mutations and aberrant nuclear expression during endometrial tumourigenesis
    • Saegusa M., Hashimura M., Yoshida T., et al. Beta-catenin mutations and aberrant nuclear expression during endometrial tumourigenesis. Br J Cancer. 84:2001;209-217
    • (2001) Br J Cancer , vol.84 , pp. 209-217
    • Saegusa, M.1    Hashimura, M.2    Yoshida, T.3
  • 22
    • 0034724443 scopus 로고    scopus 로고
    • Inhibition of integrin-linked kinase (ILK) suppresses activation of protein kinase B/Akt and induces cell cycle arrest and apoptosis of PTEN-mutant prostate cancer cells
    • Persad S., Attwell S., Gray V., et al. Inhibition of integrin-linked kinase (ILK) suppresses activation of protein kinase B/Akt and induces cell cycle arrest and apoptosis of PTEN-mutant prostate cancer cells. Proc Natl Acad Sci U S A. 97:2000;3207-3212
    • (2000) Proc Natl Acad Sci U S a , vol.97 , pp. 3207-3212
    • Persad, S.1    Attwell, S.2    Gray, V.3
  • 23
    • 0032516094 scopus 로고    scopus 로고
    • Cell adhesion and the integrin-linked kinase regulate the LEF-1 and beta-catenin signaling pathways
    • Novak A., Hsu S.C., Leung-Hagestein C., et al. Cell adhesion and the integrin-linked kinase regulate the LEF-1 and beta-catenin signaling pathways. Proc Natl Acad Sci U S A. 95:1998;4374-4379
    • (1998) Proc Natl Acad Sci U S a , vol.95 , pp. 4374-4379
    • Novak, A.1    Hsu, S.C.2    Leung-Hagestein, C.3
  • 24
    • 0031964511 scopus 로고    scopus 로고
    • Interfocal heterogeneity of PTEN/MMAC1 gene alterations in multiple metastatic prostate cancer tissues
    • Suzuki H., Freije D., Nusskern D.R., et al. Interfocal heterogeneity of PTEN/MMAC1 gene alterations in multiple metastatic prostate cancer tissues. Cancer Res. 58:1998;204-209
    • (1998) Cancer Res , vol.58 , pp. 204-209
    • Suzuki, H.1    Freije, D.2    Nusskern, D.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.