Syntabulin is a microtubule-associated protein implicated in syntaxin transport in neurons

Nature Cell Biology

Volumn 6, Issue 10, 2004, Pages 941-953

  Su, Qingning ^a   Cai, Qian ^a,b   Gerwin, Claudia ^a   Smith, Carolyn L ^a   Sheng, Zu Hang ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; KINESIN; MICROTUBULE ASSOCIATED PROTEIN; SMALL INTERFERING RNA; SYNTAXIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CONTROLLED STUDY; HIPPOCAMPUS; IN VIVO STUDY; INTRACELLULAR TRANSPORT; MICROTUBULE; NERVE ENDING; NONHUMAN; PERIKARYON; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; RAT;

AMINO ACID SEQUENCE; ANIMALS; BIOLOGICAL TRANSPORT; CARRIER PROTEINS; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; COS CELLS; GREEN FLUORESCENT PROTEINS; HIPPOCAMPUS; HUMANS; KINESIN; LUMINESCENT PROTEINS; MEMBRANE PROTEINS; MICROTUBULE PROTEINS; MICROTUBULE-ASSOCIATED PROTEINS; MICROTUBULES; MOLECULAR SEQUENCE DATA; NEURONS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; QA-SNARE PROTEINS; RECOMBINANT FUSION PROTEINS; RNA, SMALL INTERFERING; SEQUENCE HOMOLOGY, AMINO ACID; SYNTAXIN 1;

ANIMALIA;

EID: 5444235717     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/ncb1169     Document Type: Article

References (48)

1. Rothman, J. E. Mechanisms of intracellular protein transport. Nature 372, 55-63 (1994).
2. Bajjalieh, S. M. & Scheller, R.H. The biochemistry of neurotransmitter secretion. J. Biol. Chem. 270, 1971-1974 (1995).
3. Südhof, T. C. The synaptic vesicle cycle: a cascade of protein-protein interactions. Nature 375, 645-653 (1995).
4. Hilfiker, S., Greengard, P. & Augustine, G. J. Coupling calcium to SNARE-mediated synaptic vesicle fusion. Nature Neurosci. 2, 104-106 (1999).
5. Trimble, W. S., Cowan, D. M. & Scheller, R. H. VAMP-1: a synaptic vesicle-associated integral membrane protein. Proc. Natl Acad. Sci. 85, 4538-4542 (1988).
6. Bennett, M. K., Calakos, N. & Scheller, R. H. Syntaxin: a synaptic protein implicated in docking of synaptic vesicles at presynaptic active zones. Science 257, 255-259 (1992).
7. Yoshida, A., Oho, C., Omori, A., Kuwahara, R., Ito, T. & Takahashi, M. HPC-1 is associated with synaptotagmin and W-conotoxin receptor. J. Biol. Chem. 267, 24925-24928 (1992).
8. Oyler, G. A. et al. The identification of a novel synaptosomal-associated protein, SNAP-25, differentially expressed by neuronal subpopulations. J. Cell Biol. 109, 3039-3052 (1989).
9. Söllner, T. et al. SNAP receptors implicated in vesicle targeting and fusion. Nature 362, 318-324 (1993).
10. Calakos, N., Bennett, M. K., Peterson, K. & Scheller, R. H. Protein-protein interactions contributing to the specificity of intracellular vesicular trafficking. Science 263, 1146-1149 (1994).
11. Fasshauer, D., Eliason, W. K., Brünger, A. T. & Jahn, R. Identification of a minimal core of the synaptic SNARE complex sufficient for reversible assembly and disassembly. Biochemistry 37, 10354-10362 (1998).
12. Hirokawa, N. Kinesin and dynein superfamily proteins and the mechanism of organelle transport. Science 279, 519-526 (1998).
13. Brade, F. & Dotti, C. G. Membrane traffic in polarized neurons. Biochem. Biophys. Acta. 1404, 245-258 (1998).
14. Goldstein, L. S. & Philp, A. V. The road less travelled: emerging principles of kinesin motor utilization. Annu. Rev. Cell Dev. Biol. 15, 141-183 (1999).
15. Zhai, R. G. et al. Assembling the presynaptic active zone: a characterization of an active one precursor vesicle. Neuron 29, 131-143 (2001).
16. Shapira, M. et al. Unitary assembly of presynaptic active zones from Piccolo-Bassoon transport vesicles. Neuron 38, 237-252 (2003).
17. Sampo, B., Kaech, S., Kunz, S. & Banker, G. Two distinct mechanisms target membrane proteins to the axonal surface. Neuron 37, 611-24 (2003).
18. Kraszewski, K. et al. Synaptic vesicle dynamics in living cultured hippocampal neurons visualized with CY3-conjugated antibodies directed against the lumenal domain of synaptotagmin. J. Neurosci. 15, 4328-4342 (1995).
19. Nakata, T., Terada, S. & Hirokawa, N. Visualization of the dynamics of synaptic vesicle and plasma membrane proteins in living axons. J. Cell Biol. 140, 659-674 (1998).
20. Ahmari, S. E., Buchanan, J. & Smith, S. J. Assembly of presynaptic active zones from cytoplasmic transport packets. Nature Neurosci. 3, 445-451 (2000).
21. Roos, J. & Kelly, R. B. Preassembly and transport of nerve terminals: a new concept of axonal transport. Nature Neurosci. 3, 415-417 (2000).
22. Almenar-Queralt, A. & Goldstein, L. S. Linkers, packages and pathways: new concepts in axonal transport. Curr. Opin. Neurobiol. 11, 550-557 (2001).
23. Schroer, T. A. Motors, clutches and brakes for membrane traffic: a commemorative review in honor of Thomas Kreis. Traffic 1, 3-10 (2000).
24. Manning, B. D. & Snyder, M. Drivers and passengers wanted! The role of kinesin-associated proteins. Trends. Cell Biol. 10, 281-289 (2000).
25. Goldstein, L. S. & Yang, Z. Microtubule-based transport systems in neurons: the roles of kinesins and dyneins. Annu. Rev. Neurosci. 23, 39-71 (2000).
26. Kamal, A., Stokin, G. B., Yang, Z., Xia, C. H. & Goldstein, L. S. Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I. Neuron 28, 449-459 (2000).
27. Bowman, A. B. et al. Kinesin-dependent axonal transport is mediated by the sunday driver (SYD) protein. Cell 103, 583-594 (2000).
28. Nakagawa, T. et al. A novel motor, KIF13A, transports mannose-6-phosphate receptor to plasma membrane through direct interaction with AP-1 complex. Cell 103, 569-581 (2000).
29. Takeda, S. et al. Kinesin superfamily protein 3 (KIF3) motor transports fodrin-associating vesicles important for neurite building. J. Cell Biol. 148, 1255-1265 (2000).
30. Setou, M., Nakagawa, T., Seog, D. H. & Hirokawa, N. Kinesin superfamily motor protein KIF17 and mLin-10 in NMDA receptor-containing vesicle transport. Science 288, 1796-1802 (2000).
31. Kamal, A. & Goldstein, L. S. Principles of cargo attachment to cytoplasmic motor proteins. Curr. Opin. Cell Biol. 14, 63-68 (2002).
32. Lao, G. et al. Syntaphilin: a syntaxin-1 clamp that controls SNARE assembly. Neuron 25, 191-201 (2000).
33. Das, S., Gerwin, C. & Sheng, Z.-H. Syntaphilin binds to dynamin-1 and inhibits dynamin-dependent endocytosis. J. Biol. Chem. 278, 41221-41226 (2003).
34. Muresan, V. et al. Dynactin-dependent, dynein-driven vesicle transport in the absence of membrane proteins: a role for spectrin and acidic phospholipids. Mol. Cell. 7, 173-183 (2001).
35. Safieddine, S. et al. Ocsyn, a novel syntaxin-interacting protein enriched in the sub-apical region of inner hair cells. Mol. Cell. Neurosci. 20, 343-353 (2002).
36. Garcia, E. P., McPherson, P. S., Chilcote, T. J., Takei, K. & De Camilli, P. rbSec1A and B colocalize with syntaxin 1 and SNAP-25 throughout the axon, but are not in a stable complex with syntaxin. J. Cell Biol. 129, 105-20 (1995).
37. Diefenbach R. J., Mackay, J. P., Armati, P. J., & Cunningham, A. L. The C-terminal region of the Stalk domain of ubiquitous human kinesin heavy chain contains the binding site for kinesin light chain. Biochemistry 37, 16663-16670 (1998).
38. Gunawardena S. and Goldstein L. S. Cargo-carrying motor vehicles on the neuronal highway: transport pathways and neurodegenerative disease. J. Neurobiol. 58, 258-271 (2004 ).
39. Burack, M. A., Silverman, M. A. & Banker G. The role of selective transport in neuronal protein sorting. Neuron 26, 465-472 (2000).
40. Sheetz, M. P., Pfister, K. K., Bulinski, J. C. & Cotman, C. W. Mechanisms of trafficking in axons and dendrites: implications for development and neurodegeneration. Prog. Neurobiol. 55, 577-594 (1998).
41. Vale, R. D. The molecular motor toolbox for intracellular transport. Cell 112, 467-480 (2003).
42. Horton, A. C. and Ehlers, M. D. Neuronal polarity and trafficking. Neuron 40, 277-295 (2003).
43. Donaldson J. G. and Lippincott-Schwartz, J. Sorting and Signaling at the Golgi complex. Cell 101, 693-696 (2000).
44. Allan, V. J., Thompson, H. M. & McNiven, M. A. Motoring around the Golgi. Nature Cell Biol. 4, 236-242 (2002).
45. Dell, K. R. Dynactin polices two-way organelle traffic. J. Cell Biol. 160, 291-293 (2003).
46. Verhey, K. J. et al. Cargo of kinesin identified as JIP scaffolding proteins and associated signaling molecules. J. Cell Biol. 152, 959-970 (2001).
47. Lupas, A., Van, Dyke. M. & Stock, J. Predicting coiled coils from protein sequences. Science 252, 1162-1164 (1991).
48. Goslin, K., Asmussen, H. & Banker, G. in Culturing Nerve Cells 2nd edn (eds Banker, G. and Goslin, K.) 339-370 (M.I.T. Press, Cambridge, USA, 1998).