Multiple active site conformations revealed by distant site mutation in ornithine decarboxylase

Biochemistry

Volumn 43, Issue 41, 2004, Pages 12990-12999

  Jackson, Laurie K ^a   Baldwin, Jeffrey ^a   Akella, Radha ^a   Goldsmith, Elizabeth J ^a   Phillips, Margaret A ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIOSYNTHESIS; CARRIER CONCENTRATION; CATALYSIS; DATA REDUCTION; DIMERS; ENZYMES;

DIMER INTERFACE; INACTIVE CONFORMATIONS; LIGAND-BOUND SPECIES; ORNITHINE DECARBOXYLASE (ODC);

MUTAGENESIS;

ALANINE; DEXTRO ORNITHINE; DIAMINE; DIMER; GLYCINE; LEUCINE; LIGAND; LYSINE; ORNITHINE DECARBOXYLASE; ORNITHINE DERIVATIVE; PYRIDOXAL 5 PHOSPHATE; SCHIFF BASE; UNCLASSIFIED DRUG; WATER;

ARTICLE; CATALYSIS; DENSITY; ELECTRON; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME STRUCTURE; ENZYME SUBSTRATE; LIGAND BINDING; MUTANT; MUTATION; PRIORITY JOURNAL; STRUCTURE ANALYSIS; TRYPANOSOMA BRUCEI; X RAY ANALYSIS;

ALANINE; ANIMALS; BINDING SITES; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; DIAMINES; DIMERIZATION; KINETICS; LYSINE; MUTAGENESIS, SITE-DIRECTED; ORNITHINE; ORNITHINE DECARBOXYLASE; PROTEIN CONFORMATION; PUTRESCINE; PYRIDOXAL PHOSPHATE; SPECTROPHOTOMETRY, ULTRAVIOLET; TRYPANOSOMA BRUCEI BRUCEI;

TRYPANOSOMA; TRYPANOSOMA BRUCEI;

EID: 5444225208     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi048933l     Document Type: Article

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