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Volumn 14, Issue 10, 2008, Pages

Methylation of the MGMT and p16 genes in sporadic colorectal carcinoma and corresponding normal colonic mucosa

Author keywords

Colorectal cancer; DNA methylation; MGMT; p16

Indexed keywords

METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; PROTEIN P16;

EID: 54249126628     PISSN: 12341010     EISSN: 16433750     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (27)

References (31)
  • 1
    • 0034619047 scopus 로고    scopus 로고
    • ABC of colorectal cancer: Molecular basis for risk factors
    • Hardy RG, Meltzer SJ, Jankowski JA: ABC of colorectal cancer: Molecular basis for risk factors. BMJ, 2000; 321: 886-89
    • (2000) BMJ , vol.321 , pp. 886-889
    • Hardy, R.G.1    Meltzer, S.J.2    Jankowski, J.A.3
  • 2
    • 0035835486 scopus 로고    scopus 로고
    • Mutations, methylation and expresion of CDKN2a/p16 gene in colorectal cancer and normal colonic mucosa
    • Trzeciak L, Hennig E, Kolodziejski J et al: Mutations, methylation and expresion of CDKN2a/p16 gene in colorectal cancer and normal colonic mucosa. Cancer Let, 2000; 163: 17-23
    • (2000) Cancer Let , vol.163 , pp. 17-23
    • Trzeciak, L.1    Hennig, E.2    Kolodziejski, J.3
  • 3
    • 13644259457 scopus 로고    scopus 로고
    • A CpG island hypermethylation profile of primary colorectal carcinomas and colon cancer cell lines
    • Lind G, Thorstensen L, Løvig T et al: A CpG island hypermethylation profile of primary colorectal carcinomas and colon cancer cell lines. Mol Cancer, 2004; 10: 1476-84
    • (2004) Mol Cancer , vol.10 , pp. 1476-1484
    • Lind, G.1    Thorstensen, L.2    Løvig, T.3
  • 4
    • 0020699979 scopus 로고
    • Hypomethylation distinguishes genes of some human cancers from their normal counterparts
    • Feinberg A, Vogelstein B: Hypomethylation distinguishes genes of some human cancers from their normal counterparts. Nature, 1983; 301: 89-92
    • (1983) Nature , vol.301 , pp. 89-92
    • Feinberg, A.1    Vogelstein, B.2
  • 6
    • 0141537154 scopus 로고    scopus 로고
    • Aberrant CpG Island Hypermethylation of Chronic Gastritis, in Relation to Aging, Gender, Intestinal Metaplasia, and Chronic Inflammation
    • Kang GH, Lee HJ, Hwang KS: Aberrant CpG Island Hypermethylation of Chronic Gastritis, in Relation to Aging, Gender, Intestinal Metaplasia, and Chronic Inflammation. Am J Pathol, 2003; 163: 1824-30
    • (2003) Am J Pathol , vol.163 , pp. 1824-1830
    • Kang, G.H.1    Lee, H.J.2    Hwang, K.S.3
  • 7
    • 0035031279 scopus 로고    scopus 로고
    • Methylation matters
    • Costello J, Plass C: Methylation matters. J Med Genet, 2001; 38: 285-303
    • (2001) J Med Genet , vol.38 , pp. 285-303
    • Costello, J.1    Plass, C.2
  • 8
    • 0346888538 scopus 로고    scopus 로고
    • The Epigenome as a Target for Cancer Chemoprevention
    • Kopelovich L, Crowell JA, Fay JR: The Epigenome as a Target for Cancer Chemoprevention. J Natl Cancer Inst, 2003; 95: 1747-57
    • (2003) J Natl Cancer Inst , vol.95 , pp. 1747-1757
    • Kopelovich, L.1    Crowell, J.A.2    Fay, J.R.3
  • 9
    • 33344467235 scopus 로고    scopus 로고
    • Kawakami K, Ruszkiewicz A, Bennett et al: DNA hypermethylation in the normal colonic mucosa of patients with colorectal cancer. Br J Cancer, 2006; 94: 593-98
    • Kawakami K, Ruszkiewicz A, Bennett et al: DNA hypermethylation in the normal colonic mucosa of patients with colorectal cancer. Br J Cancer, 2006; 94: 593-98
  • 10
    • 0032960181 scopus 로고    scopus 로고
    • Cancer epigenetics come of age
    • Jones PA, Laird PW: Cancer epigenetics come of age. Nature Genet, 1999; 21: 163-67
    • (1999) Nature Genet , vol.21 , pp. 163-167
    • Jones, P.A.1    Laird, P.W.2
  • 11
    • 0034744639 scopus 로고    scopus 로고
    • Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer
    • Baylin SB, Esteller M, Rountree MR et al: Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer. Hum Mol Genet, 2001; 10: 687-92
    • (2001) Hum Mol Genet , vol.10 , pp. 687-692
    • Baylin, S.B.1    Esteller, M.2    Rountree, M.R.3
  • 12
    • 0033959282 scopus 로고    scopus 로고
    • The role of DNA hypermethylation in human neoplasia
    • Toyota M, Issa JP: The role of DNA hypermethylation in human neoplasia. Electrophoresis, 2000; 21: 329-33
    • (2000) Electrophoresis , vol.21 , pp. 329-333
    • Toyota, M.1    Issa, J.P.2
  • 13
    • 0032820505 scopus 로고    scopus 로고
    • Hypermethylation of the p16 gene in sporadic T3N0M0stage colorectal cancer: Association with DNA replication error and shorter survival
    • Liang JT, Chang KJ, Chen JC et al: Hypermethylation of the p16 gene in sporadic T3N0M0stage colorectal cancer: association with DNA replication error and shorter survival. Oncology, 1999; 57: 149-56
    • (1999) Oncology , vol.57 , pp. 149-156
    • Liang, J.T.1    Chang, K.J.2    Chen, J.C.3
  • 14
    • 0027769876 scopus 로고
    • A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
    • Serrano M, Hannon GJ, Beach D: A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4. Nature, 1993; 366: 704-7
    • (1993) Nature , vol.366 , pp. 704-707
    • Serrano, M.1    Hannon, G.J.2    Beach, D.3
  • 15
    • 34249825736 scopus 로고    scopus 로고
    • Molecular correlates with MGMT promoter methylation and silencing support CpG island methylator phenotype-low (CIMP-low) in colorectal cancer
    • Ogino S, Kawasaki T, Kirkner GJ et al: Molecular correlates with MGMT promoter methylation and silencing support CpG island methylator phenotype-low (CIMP-low) in colorectal cancer. Gut, 2007; 56: 1564-71
    • (2007) Gut , vol.56 , pp. 1564-1571
    • Ogino, S.1    Kawasaki, T.2    Kirkner, G.J.3
  • 16
    • 54249090673 scopus 로고    scopus 로고
    • Human colorectal mucosal 06-alkyguanine DNA-alkylotransferase activity and DNA-N7-methylguanine levels in colorectal adenoma cases and matched referents
    • Less NP, Harrison KL, Hall CN et al: Human colorectal mucosal 06-alkyguanine DNA-alkylotransferase activity and DNA-N7-methylguanine levels in colorectal adenoma cases and matched referents. Gut, 2006; 10: 1136
    • (2006) Gut , vol.10 , pp. 1136
    • Less, N.P.1    Harrison, K.L.2    Hall, C.N.3
  • 17
    • 0029843950 scopus 로고    scopus 로고
    • Methylation-specific PCR: A novel PCR assay for methylation status of CpG islands
    • Herman JG, Graf JR, Myohanen S: Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci USA, 1996; 93: 9821-26
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 9821-9826
    • Herman, J.G.1    Graf, J.R.2    Myohanen, S.3
  • 18
    • 17144425402 scopus 로고    scopus 로고
    • Hypermethylation of CpG island in 06-methylguanine-DNA methylotransferase gene was associated with K-ras G to a mutation in colorectal tumor
    • Qi J, Zhu YQ, Huang MF: Hypermethylation of CpG island in 06-methylguanine-DNA methylotransferase gene was associated with K-ras G to a mutation in colorectal tumor. World J Gastroenterol, 2005; 11: 2022-25
    • (2005) World J Gastroenterol , vol.11 , pp. 2022-2025
    • Qi, J.1    Zhu, Y.Q.2    Huang, M.F.3
  • 19
    • 33646419009 scopus 로고    scopus 로고
    • Regional hypermethylation and global hypomethylation are associated with altered chromatin conformation and histone acetylation in colorectal cancer
    • Deng G, Nguyen A, Tanaka H: Regional hypermethylation and global hypomethylation are associated with altered chromatin conformation and histone acetylation in colorectal cancer. Int J Cancer, 2006; 118: 2999-3005
    • (2006) Int J Cancer , vol.118 , pp. 2999-3005
    • Deng, G.1    Nguyen, A.2    Tanaka, H.3
  • 20
    • 0034771582 scopus 로고    scopus 로고
    • p16 gene methylation in colorectal cancers associated with Duke's staging
    • Yi J, Wang ZW, Cang H et al: p16 gene methylation in colorectal cancers associated with Duke's staging. World J Gastroenterol, 2001; 7: 722-25
    • (2001) World J Gastroenterol , vol.7 , pp. 722-725
    • Yi, J.1    Wang, Z.W.2    Cang, H.3
  • 21
    • 0032589127 scopus 로고    scopus 로고
    • Aberrant Methylation of p16 in anatomic and gender-specific subtypes of sporadic colorectal cancer
    • Wiencke JK, Zheng S, Lafuente A et al: Aberrant Methylation of p16 in anatomic and gender-specific subtypes of sporadic colorectal cancer. Cancer Epidemiol Biomarkers Prev, 1999; 8: 501-6
    • (1999) Cancer Epidemiol Biomarkers Prev , vol.8 , pp. 501-506
    • Wiencke, J.K.1    Zheng, S.2    Lafuente, A.3
  • 22
    • 0035838125 scopus 로고    scopus 로고
    • Methylation of the hMLH1, p16, and MDR1 genes in colorectal carcinoma: Associations with clinicopathological features
    • Shannon BA, Iacopetta BJ: Methylation of the hMLH1, p16, and MDR1 genes in colorectal carcinoma: associations with clinicopathological features. Cancer Let, 2001; 167: 91-97
    • (2001) Cancer Let , vol.167 , pp. 91-97
    • Shannon, B.A.1    Iacopetta, B.J.2
  • 23
    • 9244242523 scopus 로고    scopus 로고
    • Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis
    • Xu X, Yu J, Zhang H et al: Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis. World J Gastroenterol, 2004; 10: 3441-54
    • (2004) World J Gastroenterol , vol.10 , pp. 3441-3454
    • Xu, X.1    Yu, J.2    Zhang, H.3
  • 24
    • 0035870248 scopus 로고    scopus 로고
    • A Gene Hypermethylation Profile of Human Cancer
    • Esteller M, Corn PG, Baylin SB et al: A Gene Hypermethylation Profile of Human Cancer. Cancer Res, 2001; 61: 3225-29
    • (2001) Cancer Res , vol.61 , pp. 3225-3229
    • Esteller, M.1    Corn, P.G.2    Baylin, S.B.3
  • 25
    • 33744506902 scopus 로고    scopus 로고
    • Analysis of molecular alterations in left- and right-sided colorectal carcinomas reveals didtinct pathways of carcinogenesis
    • Sugai T, Habano W, Jiao Y et al: Analysis of molecular alterations in left- and right-sided colorectal carcinomas reveals didtinct pathways of carcinogenesis. J Mol Diagnostics, 2006; 8: 135-41
    • (2006) J Mol Diagnostics , vol.8 , pp. 135-141
    • Sugai, T.1    Habano, W.2    Jiao, Y.3
  • 26
    • 0036895068 scopus 로고    scopus 로고
    • Characterisation of colorectal cancers showing hypermethylation at multiple CpG islands
    • Rijnsoever M, Grieu F, Elsaleh H et al: Characterisation of colorectal cancers showing hypermethylation at multiple CpG islands. Gut, 2002; 51: 797-802
    • (2002) Gut , vol.51 , pp. 797-802
    • Rijnsoever, M.1    Grieu, F.2    Elsaleh, H.3
  • 27
    • 0035477897 scopus 로고    scopus 로고
    • Age-related Hypermethylation of the 5 Region of MLH1 in Normal Colonic Mucosa Is Associated with Microsatellite-unstable Colorectal Cancer Development
    • Nakagawa H, Nuovo GJ, Zervos E et al: Age-related Hypermethylation of the 5 Region of MLH1 in Normal Colonic Mucosa Is Associated with Microsatellite-unstable Colorectal Cancer Development. Cancer Res, 2001; 61: 6991-95
    • (2001) Cancer Res , vol.61 , pp. 6991-6995
    • Nakagawa, H.1    Nuovo, G.J.2    Zervos, E.3
  • 28
    • 0033587747 scopus 로고    scopus 로고
    • CpG island methylator phenotype in colorectal cancer
    • Toyota M, Ahuja N, Ohe-Toyota M et al: CpG island methylator phenotype in colorectal cancer. Proc Natl Acad Sci USA, 1999; 96: 8681-86
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 8681-8686
    • Toyota, M.1    Ahuja, N.2    Ohe-Toyota, M.3
  • 29
    • 0032401808 scopus 로고    scopus 로고
    • Aging and DNA methylation in colorectal mucosa and cancer
    • Ahuja N, Li Q, Mohan AL et al: Aging and DNA methylation in colorectal mucosa and cancer. Cancer Res, 1998; 58: 5489-94
    • (1998) Cancer Res , vol.58 , pp. 5489-5494
    • Ahuja, N.1    Li, Q.2    Mohan, A.L.3
  • 30
    • 0032845215 scopus 로고    scopus 로고
    • Aging, DNA methylation and cancer
    • Issa JP: Aging, DNA methylation and cancer. Crit Rev Oncol Hematol, 1999; 32: 31-43
    • (1999) Crit Rev Oncol Hematol , vol.32 , pp. 31-43
    • Issa, J.P.1
  • 31
    • 25144518262 scopus 로고    scopus 로고
    • MGMT promoter methylation and field defect in sporadic colorectal cancer
    • Shen L, Kondo Y, Rosner GL et al: MGMT promoter methylation and field defect in sporadic colorectal cancer. J Natl Cancer Inst, 2005; 97: 1330-38
    • (2005) J Natl Cancer Inst , vol.97 , pp. 1330-1338
    • Shen, L.1    Kondo, Y.2    Rosner, G.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.