Binding of calcium ions to Ras promotes Ras guanine nucleotide exchange under emulated physiological conditions

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1784, Issue 11, 2008, Pages 1560-1569

  Liao, Jun Ming ^a   Mo, Zhong Ying ^a   Wu, Ling Jia ^a   Chen, Jie ^a   Liang, Yi ^a  

^a WUHAN UNIVERSITY   (China)

Author keywords

Calcium; Isothermal titration calorimetry; Macromolecular crowding; Molecular recognition; Ras protein

Indexed keywords

CALCIUM ION; DEXTRAN 70; FICOLL; GUANOSINE DIPHOSPHATE; HYDROGEN; MAGNESIUM ION; PROTEINASE; PROTEINASE K; RAS PROTEIN; TRYPSIN;

ARTICLE; BINDING AFFINITY; BINDING SITE; CALCIUM BINDING; CONTROLLED STUDY; ENZYME DEGRADATION; FLUORESCENCE SPECTROSCOPY; ISOTHERMAL TITRATION CALORIMETRY; NONHUMAN; NUCLEOTIDE TRANSPORT; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; BINDING SITES; CALCIUM; COMPUTER SIMULATION; DOSE-RESPONSE RELATIONSHIP, DRUG; GUANINE NUCLEOTIDES; HUMANS; IONS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; OSMOLAR CONCENTRATION; PROTEIN BINDING; RAS PROTEINS; SIGNAL TRANSDUCTION;

EID: 54049135963     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbapap.2008.08.009     Document Type: Article

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