Low striatal glutamate levels underlie cognitive decline in the elderly: Evidence from in vivo molecular spectroscopy

Cerebral Cortex

Volumn 18, Issue 10, 2008, Pages 2241-2250

  Zahr, Natalie M ^a,b   Mayer, Dirk ^b,c   Pfefferbaum, Adolf ^a,b   Sullivan, Edith V ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SRI INTERNATIONAL   (United States)

^c STANFORD UNIVERSITY   (United States)

Author keywords

Aging; Cognition; Frontostriatal circuitry; Glutamate; Human; Imaging

Indexed keywords

GLUTAMIC ACID; NEUROTRANSMITTER;

AGED; AGING; ARTICLE; CEREBELLUM; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; CORPUS STRIATUM; FEMALE; FRONTAL CORTEX; HUMAN; HUMAN EXPERIMENT; MALE; METABOLITE; NEUROIMAGING; NEUROPSYCHOLOGICAL TEST; NEUROTRANSMISSION; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PONS; PRIORITY JOURNAL; SCORING SYSTEM; TASK PERFORMANCE; WORKING MEMORY; ADULT; COMPARATIVE STUDY; EFFERENT NERVE; METABOLISM; PHYSIOLOGY; PREFRONTAL CORTEX; SHORT TERM MEMORY;

ADULT; AGED; AGED, 80 AND OVER; AGING; CEREBELLUM; COGNITION; COGNITION DISORDERS; CORPUS STRIATUM; EFFERENT PATHWAYS; FEMALE; GLUTAMIC ACID; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MEMORY, SHORT-TERM; NEUROPSYCHOLOGICAL TESTS; PREFRONTAL CORTEX; YOUNG ADULT;

EID: 54049125548     PISSN: 10473211     EISSN: 14602199     Source Type: Journal    
DOI: 10.1093/cercor/bhm250     Document Type: Article

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