Effects of age and sex on volumes of the thalamus, pons, and cortex

Neurobiology of Aging

Volumn 25, Issue 2, 2004, Pages 185-192

  Sullivan, Edith V ^a   Rosenbloom, Margaret ^a,b   Serventi, Kathleen L ^c   Pfefferbaum, Adolf ^a,b  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SRI INTERNATIONAL   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Age; Cortex; Gray matter; MRI; Pons; Sex; Thalamus; White matter

Indexed keywords

ADULT; AGE; AGED; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ASSOCIATION; FEMALE; GRAY MATTER; HUMAN; MALE; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PONS; PRIORITY JOURNAL; SEX RATIO; THALAMUS; WHITE MATTER;

EID: 1642576190     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-4580(03)00044-7     Document Type: Article

References (60)

1. Adalsteinsson E., Sullivan E.V., Kleinhans N., Spielman D.M., Pfefferbaum A. Longitudinal decline of the neuronal marker N-acetyl aspartate in Alzheimer's disease. The Lancet. 355:2000;1696-1697.
2. Andreasen N.C., Paradiso S., O'Leary D.S. "Cognitive dysmetria" as an integrative theory of schizophrenia: a dysfunction in cortical-subcortical-cerebellar circuitry? Schiz. Bull. 24:1998;203-218.
3. Bartzokis G., Beckson M., Lu P.H., Nuechterlein K.H., Edwards N., Mintz J. Age-related changes in frontal and temporal lobe volumes in men: a magnetic resonance imaging study. Arch. Gen. Psychiatry. 58:2001;461-465.
4. Coffey C.E., Lucke J.E., Saxton J.A., Ratcliff G., Unitas L.J., Billig B.et al. Sex differences in brain aging: a quantitative magnetic resonance imaging study. Arch. Neurol. 55:1998;169-179.
5. Courchesne E., Chisum H.J., Townsend J., Cowles A., Covington J., Egaas B.et al. Normal brain development and aging: quantitative analysis at in vivo MR imaging in healthy volunteers. Radiology. 216:2000;672-682.
6. Cowell P.E., Turetsky B.I., Gur R.C., Grossman R.I., Shtasel D.L., Gur R.E. Sex differences in aging of the human frontal and temporal lobes. J. Neurosci. 14:1994;4748-4755.
7. Fama R., Sullivan E.V., Shear P.K., Marsh L., Yesavage J.A., Tinklenberg J.R.et al. Selective cortical and hippocampal volume correlates of Mattis Dementia Rating Scale in Alzheimer's disease. Arch. Neurol. 54:1997;719-728.
8. First MB, Spitzer RL, Gibbon M, Williams JBW. Structured clinical interview for DSM-IV axis I disorders. New York, NY: Biometrics Research Department, New York State Psychiatric Institute; 1995.
9. Folstein M.F., Folstein S.E., McHugh P.R. Mini-mental state: a practical method for grading the cognitive state of patients for the clinician. J. Psychiatr. Res. 12:1975;189-198.
10. Ge Y., Grossman R.I., Babb J.S., Rabin M.L., Mannon L.J., Kolson D.L. Age-related total gray matter and white matter changes in normal adult brain. Part I: Volumetric MR imaging analysis. Am. J. Neuroradiol. 23:2002;1327-1333.
11. Good C.D., Johnsrude I.S., Ashburner J., Henson R.N., Friston K.J., Frackowiak R.S. A voxel-based morphometric study of ageing in 465 normal adult brains. Neuroimage. 14:2001;21-36.
12. Gur R.C., Mozley P.D., Resnick S.M., Gottlieb G.L., Kohn M., Zimmerman R.et al. Gender differences in age effect on brain atrophy measured by magnetic resonance imaging. Proc. Natl. Acad. Sci. U.S.A. 88:1991;2845-2849.
13. Guttmann C.R.G., Jolesz F.A., Kikinis R., Killiany R.J., Moss M.B., Sandor T.et al. White matter changes with normal aging. Neurology. 50:1998;972-978.
14. Haber S., McFarland N.R. The place of the thalamus in frontal cortical-basal ganglia circuits. Neuroscientist. 7:2001;315-324.
15. Ilinsky I.A., Kultas-Ilinsky K. Motor thalamic circuits in primates with emphasis on the area targeted in treatment of movement disorders. Movement Disorders. 17:2002;S9-S14.
16. Jernigan T.L., Archibald S.L., Berhow M.T., Sowell E.R., Foster D.S., Hesselink J.R. Cerebral structure on MRI. 1. Localization of age-related changes. Biol. Psychiatry. 29:1991;55-67.
17. Jernigan T.L., Archibald S.L., Fennema-Notestine C., Gamst A.C., Stout J.C., Bonner J.et al. Effects of age on tissues and regions of the cerebrum and cerebellum. Neurobiol. Aging. 22:2001;581-594.
18. Jernigan T.L., Press G.A., Hesselink J.R. Methods for measuring brain morphologic features on magnetic resonance images: validation and normal aging. Arch. Neurol. 47:1990;27-32.
19. Kemper, T. In: Albert M, editor. Neuroanatomical and neuropathological changes in normal aging and in dementia. New York: Oxford University Press. Clin. Neurol. Aging 1984:9-52.
20. Kim D., Xanthakosa S.A., Tupler L.A., Barboriake D.P., Charles H.C., MacFalle J.R.et al. MR signal intensity of gray matter/white matter contrast and intracranial fat: effects of age and sex. Psychiatry Res.: Neuroimaging. 114:2002;149-161.
21. Kolmac C.I., Mitrofanis J. Patterns of brainstem projection to the thalamic reticular nucleus. J. Comp. Neurol. 396:1998;531-543.
22. Lauriello J., Hoff A., Weineke M., Blankfeld H., Faustman W.O., Rosenbloom M.et al. Similar extent of brain dysmorphology in women and men with schizophrenia. Am. J. Psychiatry. 154:1997;819-825.
23. Lim K.O., Pfefferbaum A. Segmentation of MR brain images into cerebrospinal fluid spaces. J. Comput. Assist. Tomogr. 13:1989;588-593.
24. Long J.M., Mouton P.R., Jucker M., Ingram D.K. What counts in brain aging? Design-based stereological analysis of cell number. J. Gerontol. A Biol. Sci. Med. Sci. 54:1999;B407-B417.
25. Luft A.R., Skalej M., Schulz J.B., Welte D., Kolb R., Burk K.et al. Patterns of age-related shrinkage in cerebellum and brainstem observed in vivo using three-dimensional MRI volumetry. Cereb. Cortex. 9:1999;712-721.
26. Mathalon D.H., Sullivan E.V., Rawles J.M., Pfefferbaum A. Correction for head size in brain-imaging measurements. Psychiatry Res.: Neuroimaging. 50:1993;121-139.
27. Matsumae M., Kikinis R., Morocz I.A., Lorenzo A.V., Sandor T., Albert M.S.et al. Age-related changes in intracranial compartment volumes in normal adults assessed by magnetic resonance imaging. J. Neurosurg. 84:1996;982-991.
28. Meier-Ruge W., Ulrich J., Bruhlmann M., Meier E. Age-related white matter atrophy in the human brain. Ann. NY Acad. Sci. 673:1992;260-269.
29. Middleton F.A., Strick P.L. Basal ganglia and cerebellar loops: motor and cognitive circuits. Brain Res.: Brain Res. Rev. 31:2000;236-250.
30. Miller A.K.H., Alston R.L., Corsellis J.A.N. Variations with age in the volumes of grey and white matter in the cerebral hemispheres of man: measurements with an image analyzer. Neuropathol. Appl. Neurobiol. 6:1980;119-132.
31. Murphy D.G.M., Decarli C., Mcintosh A.R., Daly E., Mentis M.J., Pietrini P.et al. Sex differences in human brain morphometry and metabolism: an in vivo quantitative magnetic resonance imaging and positron emission tomography study on the effect of aging. Arch. Gen. Psychiatry. 53:1996;585-594.
32. O'Sullivan M., Jones D., Summers P., Morris R., Williams S., Markus H. Evidence for cortical "disconnection" as a mechanism of age-related cognitive decline. Neurology. 57:2001;632-638.
33. Oguro H., Okada K., Yamaguchi S., Kobayashi S. Sex differences in morphology of the brain stem and cerebellum with normal ageing. Neuroradiology. 40:1998;788-792.
34. Pakkenberg B., Gundersen H.J.G. Neocortical neuron number in humans: effect of sex and age. J. Comp. Neurol. 384:1997;312-320.
35. Passe T., Rajagopalan P., Tupler L., Byrum C., MacFall J., Krishnan K. Age and sex effects on brain morphology. Prog. Neuro-Psychopharmacol. Biol. Psychiatry. 21:1997;1231-1237.
36. Pfefferbaum A., Adalsteinsson E., Spielman D., Sullivan E.V., Lim K.O. In vivo spectroscopic quantification of the N-acetyl moiety, creatine and choline from large volumes of gray and white matter: effects of normal aging. Magnetic Resonance Med. 41:1999;276-284.
37. Pfefferbaum A., Lim K.O., Desmond J., Sullivan E.V. Thinning of the corpus callosum in older alcoholic men: a magnetic resonance imaging study. Alcohol Clin. Exp. Res. 20:1996;752-757.
38. Pfefferbaum A., Lim K.O., Zipursky R.B., Mathalon D.H., Lane B., Ha C.N.et al. Brain gray and white matter volume loss accelerates with aging in chronic alcoholics: a quantitative MRI study. Alcohol Clin. Exp. Res. 16:1992;1078-1089.
39. Pfefferbaum A., Mathalon D.H., Sullivan E.V., Rawles J.M., Zipursky R.B., Lim K.O. A quantitative magnetic resonance imaging study of changes in brain morphology from infancy to late adulthood. Arch. Neurol. 51:1994;874-887.
40. Pfefferbaum A., Rosenbloom M.J., Deshmukh A., Sullivan E.V. Sex differences in the effects of alcohol on brain structure. Am. J. Psychiatry. 158:2001;188-197.
41. Pfefferbaum A., Rosenbloom M.J., Serventi K., Sullivan E.V. Corpus callosum, pons and cortical white matter in alcoholic women. Alcohol Clin. Exp. Res. 26:2002;400-405.
42. Pfefferbaum A, Sullivan EV. Increased brain white matter diffusivity in normal adult aging: relationship to anisotropy. Magnetic Resonance Med. 2003 (in press).
43. Pfefferbaum A., Sullivan E.V., Hedehus M., Lim K.O., Adalsteinsson E., Moseley M. Age-related decline in brain white matter anisotropy measured with spatially corrected echo-planar diffusion tensor imaging. Magnetic Resonance Med. 44:2000;259-268.
44. Raz N., Gunning F.M., Head D., Dupuis J.H., McQuain J., Briggs S.D.et al. Selective aging of the human cerebral cortex observed in vivo: differential vulnerability of the prefrontal gray matter. Cereb. Cortex. 7:1997;268-282.
45. Raz N., Gunning-Dixon F., Head D., Williamson A., Acker J.D. Age and sex differences in the cerebellum and the ventral pons: a prospective MR study of healthy adults. Am. J. Neuroradiol. 22:2001;1161-1167.
46. Salat D.H., Kaye J.A., Janowsky J.S. Prefrontal gray and white matter volumes in healthy aging and Alzheimer disease. Arch. Neurol. 56:1999;338-344.
47. Schmahmann J.D., Pandya D.N. Anatomical investigation of projections from thalamus to posterior parietal cortex in the rhesus monkey: a WGA-HRP and fluorescent tracer study. J. Comp. Neurol. 295:1990;299-326.
48. Schmahmann J.D., Pandya D.N. Anatomic organization of the basilar pontine projections from prefrontal cortices in rhesus monkey. J. Neurosci. 17:1997;438-458.
49. Skinner, H. A. Development and validation of a lifetime alcohol consumption assessment procedure. Toronto, Canada: Addiction Research Foundation; 1982.
50. Spitzer R.L., Williams J.B.W., Gibbon M., First M.B. The structured clinical interview for DSM-III-R (SCID) 1. History, rationale, and description. Arch. Gen. Psychiatry. 49:1992;624-629.
51. Sullivan E.V., Adalsteinsson E., Hedehus M., Ju C., Moseley M., Lim K.O.et al. Equivalent disruption of regional white matter microstructure in aging healthy men and women. Neuroreport. 12:2001;99-104.
52. Sullivan E.V., Deshmukh A., Desmond J.E., Lim K.O., Pfefferbaum A. Cerebellar volume decline in normal aging, alcoholism, and Korsakoff's syndrome: relation to ataxia. Neuropsychology. 14:2000;341-352.
53. Sullivan E.V., Lim K.O., Mathalon D.H., Marsh L., Beal D.M., Harris D.et al. A profile of cortical gray matter volume deficits characteristic of schizophrenia. Cereb. Cortex. 8:1998;117-124.
54. Sullivan E.V., Rosenbloom M.J., Desmond J.E., Pfefferbaum A. Sex differences in corpus callosum size: relationship to age and intracranial size. Neurobiol. Aging. 22:2001;603-611.
55. Sullivan EV, Rosenbloom MJ, Serventi KL, Deshmukh A, Pfefferbaum A. The effects of alcoholism-schizophrenia comorbidity on volumes of the thalamus and pons. Am. J. Psychiatry 2003 (in press).
56. Tang Y., Nyengaard J.R., Pakkenberg B., Gundersen H.J.G. Age-induced white-matter changes in the human brain: a stereological investigation. Neurobiol. Aging. 18:1997;609-615.
57. Tang Y., Whitman G.T., Lopez I., Baloh R.W. Brain volume changes on longitudinal magnetic resonance imaging in normal older people. J. Neuroimaging. 11:2001;393-400.
58. Turlejski K., Djavadian R. Life-long stability of neurons: a century of research on neurogenesis, neuronal death and neuron quantification in adult CNS. Prog. Brain Res. 136:2002;39-65.
59. Van Der Werf Y.D., Tisserand D.J., Visser P.J., Hofman P.A., Vuurman E., Uylings H.B.et al. Thalamic volume predicts performance on tests of cognitive speed and decreases in healthy aging. A magnetic resonance imaging-based volumetric analysis. Brain Res. Cogn. Brain Res. 11:2001;377-385.
60. Xu J., Kobayashi S., Yamaguchi S., Iijima K., Okada K., Yamashita K. Gender effects on age-related changes in brain structure. Am. J. Neuroradiol. 21:2000;112-118.