-
1
-
-
0030798245
-
Histone acetylation in chromatin structure and transcription
-
Grunstein M. Histone acetylation in chromatin structure and transcription. Nature. 1997;389:349-352.
-
(1997)
Nature
, vol.389
, pp. 349-352
-
-
Grunstein, M.1
-
2
-
-
78651162036
-
Acetylation and methylation of histones and their possible role in the regulation of RNA synthesis
-
Allfrey VG, Faulknere R, Mirsky AE. Acetylation and methylation of histones and their possible role in the regulation of RNA synthesis. Proc Natl Acad Sci U S A. 1964;61:786-794.
-
(1964)
Proc Natl Acad Sci U S A
, vol.61
, pp. 786-794
-
-
Allfrey, V.G.1
Faulknere, R.2
Mirsky, A.E.3
-
3
-
-
0030916336
-
What's up and down with histone deacetylation and transcription?
-
Pazin MJ, Kadonaga JT. What's up and down with histone deacetylation and transcription? Cell. 1997;89:325-328.
-
(1997)
Cell
, vol.89
, pp. 325-328
-
-
Pazin, M.J.1
Kadonaga, J.T.2
-
4
-
-
0034596309
-
Histone deacetylase inhibitors: Inducers of differentiation or apoptosis of transformed cells
-
Marks PA, Richon VM, Rifkind RA. Histone deacetylase inhibitors: Inducers of differentiation or apoptosis of transformed cells. J Natl Cancer Inst. 2000;92:1210-1216.
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 1210-1216
-
-
Marks, P.A.1
Richon, V.M.2
Rifkind, R.A.3
-
5
-
-
0033522479
-
The E7 oncoprotein associates with Mi2 and histone deacetylase activity to promote cell growth
-
Brehm A, Nielsen SJ, Miska EA, et al. The E7 oncoprotein associates with Mi2 and histone deacetylase activity to promote cell growth. EMBO J. 1999;18:2449-2458.
-
(1999)
EMBO J
, vol.18
, pp. 2449-2458
-
-
Brehm, A.1
Nielsen, S.J.2
Miska, E.A.3
-
6
-
-
0034104047
-
Mutations truncating the EP300 acetylase in human cancers
-
Gayther SA, Batley SJ, Linger L, et al. Mutations truncating the EP300 acetylase in human cancers. Nat Genet. 2000;24:300-303.
-
(2000)
Nat Genet
, vol.24
, pp. 300-303
-
-
Gayther, S.A.1
Batley, S.J.2
Linger, L.3
-
7
-
-
17144458786
-
Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukemia
-
Grignani F, De Matteis S, Nervi C, Tomassoni L, Gelmetti V, Cioce M. Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukemia. Nature. 1998;391:815-818.
-
(1998)
Nature
, vol.391
, pp. 815-818
-
-
Grignani, F.1
De Matteis, S.2
Nervi, C.3
Tomassoni, L.4
Gelmetti, V.5
Cioce, M.6
-
8
-
-
0032546017
-
Role of the histone deacetylase complex in acute promyelocytic leukemia
-
Lin RJ, Nagy L, Inoue S, Shao W, Miller WH. Jr, Evans RM. Role of the histone deacetylase complex in acute promyelocytic leukemia. Nature. 1998;391:811-814.
-
(1998)
Nature
, vol.391
, pp. 811-814
-
-
Lin, R.J.1
Nagy, L.2
Inoue, S.3
Shao, W.4
Miller W.H., Jr.5
Evans, R.M.6
-
9
-
-
0031941912
-
Distinct interactions of PML-RARalpha and PLZF-RARalpha with corepressors determine differential responses to RA in APL
-
He LZ, Guidez F, Tribioli C, Peruzzi D, Ruthardt M, Zelent A. Distinct interactions of PML-RARalpha and PLZF-RARalpha with corepressors determine differential responses to RA in APL. Nat Genet. 1998;18:126-135.
-
(1998)
Nat Genet
, vol.18
, pp. 126-135
-
-
He, L.Z.1
Guidez, F.2
Tribioli, C.3
Peruzzi, D.4
Ruthardt, M.5
Zelent, A.6
-
10
-
-
3643104150
-
Therapeutic targeting of transcription in acute promyelocytic leukemia by use of an inhibitor of histone deacetylase
-
Warrel RP, He L-Z, Richon V, Calleja E, Pandolfi PP. Therapeutic targeting of transcription in acute promyelocytic leukemia by use of an inhibitor of histone deacetylase. J Natl Cancer Inst. 1998;90:1621-1625.
-
(1998)
J Natl Cancer Inst
, vol.90
, pp. 1621-1625
-
-
Warrel, R.P.1
He, L.-Z.2
Richon, V.3
Calleja, E.4
Pandolfi, P.P.5
-
11
-
-
0033551152
-
A synthetic inhibitor of histone deacetylase, MS-27-275, with marked in vivo anti-tumor activity against human tumors
-
Saito A, Yamashita T, Mariko Y, et al. A synthetic inhibitor of histone deacetylase, MS-27-275, with marked in vivo anti-tumor activity against human tumors. Proc Natl Acad Sci U S A. 1999;96:4592-4597.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 4592-4597
-
-
Saito, A.1
Yamashita, T.2
Mariko, Y.3
-
12
-
-
0034672294
-
Effect of trichostatin A on cell growth and expression of cell cycle and apoptosis-related molecules in human gastric and oral carcinoma cell lines
-
Suzuki T, Yokozaki H, Kuniyasu H, et al. Effect of trichostatin A on cell growth and expression of cell cycle and apoptosis-related molecules in human gastric and oral carcinoma cell lines. Int J Cancer. 2000;88:992-997.
-
(2000)
Int J Cancer
, vol.88
, pp. 992-997
-
-
Suzuki, T.1
Yokozaki, H.2
Kuniyasu, H.3
-
13
-
-
0026507070
-
Novel anticancer prodrugs of butyric acid
-
Nudelman A, Ruse M, Aviram A, et al. Novel anticancer prodrugs of butyric acid. J Med Chem. 1992;35:687-694.
-
(1992)
J Med Chem
, vol.35
, pp. 687-694
-
-
Nudelman, A.1
Ruse, M.2
Aviram, A.3
-
14
-
-
0030906964
-
Effect of butyric acid pro-drug, pivaloyloxymethyl butyrate, on the tumorigenicity of cancer cells
-
Aviram A, Rephaeli A, Shaklai M, et al. Effect of butyric acid pro-drug, pivaloyloxymethyl butyrate, on the tumorigenicity of cancer cells. J Cancer Res Clin Oncol. 1997;123:267-271.
-
(1997)
J Cancer Res Clin Oncol
, vol.123
, pp. 267-271
-
-
Aviram, A.1
Rephaeli, A.2
Shaklai, M.3
-
15
-
-
0007977581
-
Pivaloyloxymethyl butyrate (AN-9) exhibits higher anticancer activity than butyric acid (BA): It penetrates faster than the acid and induces apoptosis in HL60 cells
-
Zimra Y, Maron L. Shaklai M. Nudelman A, Rephaeli A. Pivaloyloxymethyl butyrate (AN-9) exhibits higher anticancer activity than butyric acid (BA): It penetrates faster than the acid and induces apoptosis in HL60 cells. Blood. 1994;84:579a.
-
(1994)
Blood
, vol.84
-
-
Zimra, Y.1
Maron, L.2
Shaklai, M.3
Nudelman, A.4
Rephaeli, A.5
-
16
-
-
0025862375
-
Derivatives of butyric acid as potential anti-neoplastic agents
-
Rephaeli A. Rabizadeh E, Aviram A, Shaklai M, Ruse M, Nudelman A. Derivatives of butyric acid as potential anti-neoplastic agents. Int J Cancer. 1991;49:66-72.
-
(1991)
Int J Cancer
, vol.49
, pp. 66-72
-
-
Rephaeli, A.1
Rabizadeh, E.2
Aviram, A.3
Shaklai, M.4
Ruse, M.5
Nudelman, A.6
-
17
-
-
0031730897
-
Activity of pivaloyloxymethyl butyrate, a novel anticancer agent, on primary human tumor colony-forming units
-
Siu LL, Von Hoff DD, Rephaeli A, et al. Activity of pivaloyloxymethyl butyrate, a novel anticancer agent, on primary human tumor colony-forming units. Invest New Drugs. 1998;16:113-119.
-
(1998)
Invest New Drugs
, vol.16
, pp. 113-119
-
-
Siu, L.L.1
Von Hoff, D.D.2
Rephaeli, A.3
-
18
-
-
0030957625
-
Butyric acid and pivaloyloxymethyl butyrate, AN-9, a novel butyric acid derivative, induce apoptosis in HL60 cells
-
Zimra Y, Wasserman L, Maron L, Shaklai M, Rephaeli A, Nudelman A. Butyric acid and pivaloyloxymethyl butyrate, AN-9, a novel butyric acid derivative, induce apoptosis in HL60 cells. J Cancer Res Clin Oncol. 1997;123:152-160.
-
(1997)
J Cancer Res Clin Oncol
, vol.123
, pp. 152-160
-
-
Zimra, Y.1
Wasserman, L.2
Maron, L.3
Shaklai, M.4
Rephaeli, A.5
Nudelman, A.6
-
19
-
-
0031046409
-
An anticancer derivative of butyric acid (pivaloyloxymethyl butyrate) and daunorubicin cooperatively prolong survival of mice inoculated with monocytic leukemia cells
-
Kasukabe T, Rephaeli A, Honma Y. An anticancer derivative of butyric acid (pivaloyloxymethyl butyrate) and daunorubicin cooperatively prolong survival of mice inoculated with monocytic leukemia cells. Br J Cancer. 1997;75:850-854.
-
(1997)
Br J Cancer
, vol.75
, pp. 850-854
-
-
Kasukabe, T.1
Rephaeli, A.2
Honma, Y.3
-
20
-
-
0030939976
-
Characterization of cellular accumulation and toxicity of illudin S in sensitive and nonsensitive tumor cells
-
Kelner MJ, McMorris TC, Montoya MA, et al. Characterization of cellular accumulation and toxicity of illudin S in sensitive and nonsensitive tumor cells. Cancer Chemother Pharmacol. 1997;40:65-71.
-
(1997)
Cancer Chemother Pharmacol
, vol.40
, pp. 65-71
-
-
Kelner, M.J.1
McMorris, T.C.2
Montoya, M.A.3
-
21
-
-
0023272741
-
Doxorubicin resistance in HL60 cells and accompanying modification of a surface membrane protein contained in drug-sensitive cells
-
Marsh W, Center MS. Doxorubicin resistance in HL60 cells and accompanying modification of a surface membrane protein contained in drug-sensitive cells. Cancer Res. 1987;47:5080-5086.
-
(1987)
Cancer Res
, vol.47
, pp. 5080-5086
-
-
Marsh, W.1
Center, M.S.2
-
22
-
-
0025943712
-
Multidrug resistance in human neuroblastoma cells
-
LaQuaglia MP, Kopp EB, Spengler BA, Meyers MB, Biedler JL. Multidrug resistance in human neuroblastoma cells. J Pediatr Surg. 1991;26:1107-1112.
-
(1991)
J Pediatr Surg
, vol.26
, pp. 1107-1112
-
-
LaQuaglia, M.P.1
Kopp, E.B.2
Spengler, B.A.3
Meyers, M.B.4
Biedler, J.L.5
-
24
-
-
0033963601
-
Involvement of p21(Waf1/Cip1) and its cleavage by DEVD-caspase during apoptosis of colorectal cancer cells induced by butyrate
-
Chai F, Evdokiou A, Young GP, Zalewski PD. Involvement of p21(Waf1/Cip1) and its cleavage by DEVD-caspase during apoptosis of colorectal cancer cells induced by butyrate. Carcinogenesis. 2000;21:7-14.
-
(2000)
Carcinogenesis
, vol.21
, pp. 7-14
-
-
Chai, F.1
Evdokiou, A.2
Young, G.P.3
Zalewski, P.D.4
-
25
-
-
0011062148
-
A phase I study of AN-9 (pivaloyloxymethyl butyrate. Pivanex™), a lipophilic butyric acid analog, in patients with advanced solid tumors
-
Eckhardt SG, Villalona-Calero MA, Hammond L, et al. A phase I study of AN-9 (pivaloyloxymethyl butyrate. Pivanex™), a lipophilic butyric acid analog, in patients with advanced solid tumors. Proc Am Assoc Cancer Res. 1998;39:507.
-
(1998)
Proc Am Assoc Cancer Res
, vol.39
, pp. 507
-
-
Eckhardt, S.G.1
Villalona-Calero, M.A.2
Hammond, L.3
-
26
-
-
0023582056
-
Comparison of the sensitivity of normal and leukaemic myeloid progenitors to in-vitro incubation with cytotoxic drugs: A study of pharmacological purging
-
Singer CRJ, Linch DC, Comparison of the sensitivity of normal and leukaemic myeloid progenitors to in-vitro incubation with cytotoxic drugs: A study of pharmacological purging. Leuk Res. 1987;11:953-959.
-
(1987)
Leuk Res
, vol.11
, pp. 953-959
-
-
Singer, C.R.J.1
Linch, D.C.2
-
27
-
-
0019495252
-
Sensitivity of myeloid progenitor cells in healthy subjects and patients with chronic myeloid leukemia to chemotherapeutic agents
-
Spiro TE, Mattelaer M-A, Efira A, Stryckmans P. Sensitivity of myeloid progenitor cells in healthy subjects and patients with chronic myeloid leukemia to chemotherapeutic agents. J Natl Cancer Inst. 1981;66:1053-1059.
-
(1981)
J Natl Cancer Inst
, vol.66
, pp. 1053-1059
-
-
Spiro, T.E.1
Mattelaer, M.-A.2
Efira, A.3
Stryckmans, P.4
-
28
-
-
0027253237
-
Plasma and cellular pharmacokinetics of m-AMSA related to in vitro toxicity towards normal and leukemic clonogenic bone marrow cells (CFU-GM, CFU-L)
-
Linssen P, Brons P, Knops G, Wessels H, de Witte T. Plasma and cellular pharmacokinetics of m-AMSA related to in vitro toxicity towards normal and leukemic clonogenic bone marrow cells (CFU-GM, CFU-L). Eur J Haematol. 1993;50:149-154.
-
(1993)
Eur J Haematol
, vol.50
, pp. 149-154
-
-
Linssen, P.1
Brons, P.2
Knops, G.3
Wessels, H.4
De Witte, T.5
-
29
-
-
0031596491
-
Butyrate-induced G1 arrest results from p21-independent disruption of retinoblastoma protein-mediated signals
-
Vaziri C, Stice L, Faller DV. Butyrate-induced G1 arrest results from p21-independent disruption of retinoblastoma protein-mediated signals. Cell Growth Differ. 1998;9:465-474.
-
(1998)
Cell Growth Differ
, vol.9
, pp. 465-474
-
-
Vaziri, C.1
Stice, L.2
Faller, D.V.3
-
30
-
-
0030796349
-
Induction of caspase-3 protease activity and apoptosis by butyrate and trichostatin A (inhibitors of histone deacetylase). Dependence on protein synthesis and synergy with a mitochondrial/cytochrome c-dependent pathway
-
Medina V, Edmonds B, Young GP, James R, Appleton S, Zalewski PD. Induction of caspase-3 protease activity and apoptosis by butyrate and trichostatin A (inhibitors of histone deacetylase). Dependence on protein synthesis and synergy with a mitochondrial/cytochrome c-dependent pathway. Cancer Res. 1997;57:3697-3707.
-
(1997)
Cancer Res
, vol.57
, pp. 3697-3707
-
-
Medina, V.1
Edmonds, B.2
Young, G.P.3
James, R.4
Appleton, S.5
Zalewski, P.D.6
-
31
-
-
7344225513
-
Cancer cell sensitization to fas-mediated apoptosis by sodium butyrate
-
Bonnotte B, Favre N, Reveneau S, et al. Cancer cell sensitization to fas-mediated apoptosis by sodium butyrate. Cell Death Differ. 1998;5:480-487.
-
(1998)
Cell Death Differ
, vol.5
, pp. 480-487
-
-
Bonnotte, B.1
Favre, N.2
Reveneau, S.3
-
32
-
-
0033524353
-
Frequent deregulation of p16 and the p16/G1 cell cycle-regulatory pathway in neuroblastoma
-
Diccianni MB, Omura-Minamisawa M, Batova A, Le T, Bridgeman L, Yu AL. Frequent deregulation of p16 and the p16/G1 cell cycle-regulatory pathway in neuroblastoma. Int J Cancer. 1999;80:145-154.
-
(1999)
Int J Cancer
, vol.80
, pp. 145-154
-
-
Diccianni, M.B.1
Omura-Minamisawa, M.2
Batova, A.3
Le, T.4
Bridgeman, L.5
Yu, A.L.6
-
33
-
-
0033948989
-
Anticancer derivative of butyric acid (pivalyloxymethyl butyrate) specifically potentiates the cytotoxicity of doxorubicin and daunorubicin through the suppression of microsomal glycosidic activity
-
Niitsu N, Kasukabe T, Yokoyama A, et al. Anticancer derivative of butyric acid (pivalyloxymethyl butyrate) specifically potentiates the cytotoxicity of doxorubicin and daunorubicin through the suppression of microsomal glycosidic activity. Mol Pharmacol. 2000;58:27-36.
-
(2000)
Mol Pharmacol
, vol.58
, pp. 27-36
-
-
Niitsu, N.1
Kasukabe, T.2
Yokoyama, A.3
-
34
-
-
0035890824
-
Molecular basis for the synergistic interaction of doxorubicin with the formaldehyde-releasing prodrug pivaloyloxymethyl butyrate (AN-9)
-
Cutts SM, Rephaeli A, Nudelman A, Hmelnitsky I, Phillips DR. Molecular basis for the synergistic interaction of doxorubicin with the formaldehyde-releasing prodrug pivaloyloxymethyl butyrate (AN-9). Cancer Res. 2001;61:8194-8202.
-
(2001)
Cancer Res
, vol.61
, pp. 8194-8202
-
-
Cutts, S.M.1
Rephaeli, A.2
Nudelman, A.3
Hmelnitsky, I.4
Phillips, D.R.5
|