메뉴 건너뛰기




Volumn 24, Issue 10, 2008, Pages 1291-1300

Impact of human immunodeficiency virus type 1 reverse transcriptase inhibitor drug resistance mutation interactions on phenotypic susceptibility

Author keywords

[No Author keywords available]

Indexed keywords

ABACAVIR; DIDANOSINE; LAMIVUDINE; NEVIRAPINE; RNA DIRECTED DNA POLYMERASE INHIBITOR; STAVUDINE; TENOFOVIR; ZIDOVUDINE;

EID: 53849136952     PISSN: 08892229     EISSN: None     Source Type: Journal    
DOI: 10.1089/aid.2007.0244     Document Type: Article
Times cited : (9)

References (61)
  • 2
    • 33846440130 scopus 로고    scopus 로고
    • Clinical utility of HIV standard genotyping among antiretroviral-naive individuals with unknown duration of infection
    • Smith D, Moini N, Pesano R, Cachay E, Aiem H, Lie Y, et al.: Clinical utility of HIV standard genotyping among antiretroviral-naive individuals with unknown duration of infection. Clin Infect Dis 2007;44:456-458.
    • (2007) Clin Infect Dis , vol.44 , pp. 456-458
    • Smith, D.1    Moini, N.2    Pesano, R.3    Cachay, E.4    Aiem, H.5    Lie, Y.6
  • 3
    • 0035020615 scopus 로고    scopus 로고
    • Long-term benefit of genotypic-guided therapy and prevalence of multinucleoside resistance in an Italian group of antiretroviral multiexperienced patients
    • Quiros-Roldan E, Moretti F, Airoldi M, Fausti C, Chiodera A, Castelli F, et al.: Long-term benefit of genotypic-guided therapy and prevalence of multinucleoside resistance in an Italian group of antiretroviral multiexperienced patients. J Clin Lab Anal 2001;15:127-130.
    • (2001) J Clin Lab Anal , vol.15 , pp. 127-130
    • Quiros-Roldan, E.1    Moretti, F.2    Airoldi, M.3    Fausti, C.4    Chiodera, A.5    Castelli, F.6
  • 4
    • 0035141058 scopus 로고    scopus 로고
    • Patterns of resistance mutations to antiretroviral drugs in extensively treated HIV-1-infected patients with failure of highly active antiretroviral therapy
    • Rousseau MN, Vergne L, Montes B, Peeters M, Reynes J, Delaporte E, et al.: Patterns of resistance mutations to antiretroviral drugs in extensively treated HIV-1-infected patients with failure of highly active antiretroviral therapy. J Acquir Immune Defic Syndr 2001;26:36-43.
    • (2001) J Acquir Immune Defic Syndr , vol.26 , pp. 36-43
    • Rousseau, M.N.1    Vergne, L.2    Montes, B.3    Peeters, M.4    Reynes, J.5    Delaporte, E.6
  • 5
    • 0034102129 scopus 로고    scopus 로고
    • Frequency of antiretroviral drug resistance mutations in HIV-1 strains from patients failing triple drug regimens. The Terry Beirn Community Programs for Clinical Research on AIDS
    • Winters MA, Baxter JD, Mayers DL, Wentworth DN, Hoover ML, Neaton JD, et al.: Frequency of antiretroviral drug resistance mutations in HIV-1 strains from patients failing triple drug regimens. The Terry Beirn Community Programs for Clinical Research on AIDS. Antiviral Ther 2000;5:57-63.
    • (2000) Antiviral Ther , vol.5 , pp. 57-63
    • Winters, M.A.1    Baxter, J.D.2    Mayers, D.L.3    Wentworth, D.N.4    Hoover, M.L.5    Neaton, J.D.6
  • 8
    • 3142660152 scopus 로고    scopus 로고
    • The prevalence of antiretroviral drug resistance in the United States
    • Richman DD, Morton SC, Wrin T, Hellmann N, Berry S, Shapiro MF, et al.: The prevalence of antiretroviral drug resistance in the United States. AIDS 2004;18:1393-1401.
    • (2004) AIDS , vol.18 , pp. 1393-1401
    • Richman, D.D.1    Morton, S.C.2    Wrin, T.3    Hellmann, N.4    Berry, S.5    Shapiro, M.F.6
  • 9
    • 0036721138 scopus 로고    scopus 로고
    • Combination of drugs and drug-resistant reverse transcriptase results in a multiplicative increase of human immunodeficiency virus type 1 mutant frequencies
    • Mansky LM, Pearl DK, and Gajary LC: Combination of drugs and drug-resistant reverse transcriptase results in a multiplicative increase of human immunodeficiency virus type 1 mutant frequencies. J Virol 2002;76:9253-9259.
    • (2002) J Virol , vol.76 , pp. 9253-9259
    • Mansky, L.M.1    Pearl, D.K.2    Gajary, L.C.3
  • 10
    • 0037343865 scopus 로고    scopus 로고
    • Mutagenic outcome of combined antiviral drug treatment during human immunodeficiency virus type 1 replication
    • Mansky LM: Mutagenic outcome of combined antiviral drug treatment during human immunodeficiency virus type 1 replication. Virol 2003;307:116-121.
    • (2003) Virol , vol.307 , pp. 116-121
    • Mansky, L.M.1
  • 11
    • 0142042463 scopus 로고    scopus 로고
    • Broad nucleoside reverse-transcriptase inhibitor cross-resistance in human immunodeficiency virus type 1 clinical isolates
    • Whitcomb JM, Parkin NT, Chappey C, Hellmann NS, and Petropoulos CJ: Broad nucleoside reverse-transcriptase inhibitor cross-resistance in human immunodeficiency virus type 1 clinical isolates. J Infect Dis 2003;188:992-1000.
    • (2003) J Infect Dis , vol.188 , pp. 992-1000
    • Whitcomb, J.M.1    Parkin, N.T.2    Chappey, C.3    Hellmann, N.S.4    Petropoulos, C.J.5
  • 12
    • 0037076711 scopus 로고    scopus 로고
    • Tenofovir DF in antiretroviral-experienced patients: Results from a 48-week, randomized, double-blind study
    • Schooley RT, Ruane P, Myers RA, Beall G, Lampiris H, Berger D, et al.: Tenofovir DF in antiretroviral-experienced patients: Results from a 48-week, randomized, double-blind study. AIDS 2002;16:1257-1263.
    • (2002) AIDS , vol.16 , pp. 1257-1263
    • Schooley, R.T.1    Ruane, P.2    Myers, R.A.3    Beall, G.4    Lampiris, H.5    Berger, D.6
  • 14
    • 3042848853 scopus 로고    scopus 로고
    • Efficacy and safety of tenofovir DF vs stavudine in combination therapy in antiretroviral-naive patients: A 3-year randomized trial
    • Gallant JE, Staszewski S, Pozniak AL, DeJesus E, Suleiman JM, Miller MD, et al.: Efficacy and safety of tenofovir DF vs stavudine in combination therapy in antiretroviral-naive patients: A 3-year randomized trial. JAMA 2004;292:191-201.
    • (2004) JAMA , vol.292 , pp. 191-201
    • Gallant, J.E.1    Staszewski, S.2    Pozniak, A.L.3    DeJesus, E.4    Suleiman, J.M.5    Miller, M.D.6
  • 15
    • 1542327561 scopus 로고    scopus 로고
    • Genotypic and phenotypic predictors of the magnitude of response to tenofovir disoproxil fumarate treatment in antiretroviral-experienced patients
    • Miller MD, Margot N, Lu B, Zhong L, Chen S, Cheng A, et al.: Genotypic and phenotypic predictors of the magnitude of response to tenofovir disoproxil fumarate treatment in antiretroviral-experienced patients. J Infect Dis 2004;189:837-846.
    • (2004) J Infect Dis , vol.189 , pp. 837-846
    • Miller, M.D.1    Margot, N.2    Lu, B.3    Zhong, L.4    Chen, S.5    Cheng, A.6
  • 16
    • 14844300816 scopus 로고    scopus 로고
    • Didanosine in HIV-1-infected patients experiencing failure of antiretroviral therapy: A randomized placebo-controlled trial
    • Molina JM, Marcelin AG, Pavie J, Heripret L, De Boever CM, Troccaz M, et al.: Didanosine in HIV-1-infected patients experiencing failure of antiretroviral therapy: A randomized placebo-controlled trial. J Infect Dis 2005;191:840-847.
    • (2005) J Infect Dis , vol.191 , pp. 840-847
    • Molina, J.M.1    Marcelin, A.G.2    Pavie, J.3    Heripret, L.4    De Boever, C.M.5    Troccaz, M.6
  • 18
    • 0027285372 scopus 로고
    • Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3′-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase
    • Tisdale M, Kemp SD, Parry NR, and Larder BA.: Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3′-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase. Proc Natl Acad Sci USA 1993;90:5653-5656.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 5653-5656
    • Tisdale, M.1    Kemp, S.D.2    Parry, N.R.3    Larder, B.A.4
  • 20
    • 0033166659 scopus 로고    scopus 로고
    • Development and significance of the HIV-1 reverse transcriptase M184V mutation during combination therapy with lamivudine, zidovudine, and protease inhibitors
    • Catucci M, Venturi G, Romano L, Riccio ML, De Milito A, Valensin PE, et al.: Development and significance of the HIV-1 reverse transcriptase M184V mutation during combination therapy with lamivudine, zidovudine, and protease inhibitors. J Acquir Immune Defic Syndr 1999;21:203-208.
    • (1999) J Acquir Immune Defic Syndr , vol.21 , pp. 203-208
    • Catucci, M.1    Venturi, G.2    Romano, L.3    Riccio, M.L.4    De Milito, A.5    Valensin, P.E.6
  • 21
    • 4143088125 scopus 로고    scopus 로고
    • Phenotypic impact of HIV reverse transcriptase M184I/V mutations in combination with single thymidine analog mutations on nucleoside reverse transcriptase inhibitor resistance
    • Ross L, Parkin N, Chappey C, Fisher R, Clair MS, Bates M, et al.: Phenotypic impact of HIV reverse transcriptase M184I/V mutations in combination with single thymidine analog mutations on nucleoside reverse transcriptase inhibitor resistance. AIDS 2004;18:1691-1696.
    • (2004) AIDS , vol.18 , pp. 1691-1696
    • Ross, L.1    Parkin, N.2    Chappey, C.3    Fisher, R.4    Clair, M.S.5    Bates, M.6
  • 22
    • 0035876456 scopus 로고    scopus 로고
    • Phenotypic hypersusceptibility to nonnucleoside reverse transcriptase inhibitors in treatment-experienced HIV-infected patients: Impact on virological response to efavirenz-based therapy
    • Shulman N, Zolopa AR, Passaro D, Shafer RW, Huang W, Katzenstein D, et al.: Phenotypic hypersusceptibility to nonnucleoside reverse transcriptase inhibitors in treatment-experienced HIV-infected patients: Impact on virological response to efavirenz-based therapy. AIDS 2001;15:1125-1132.
    • (2001) AIDS , vol.15 , pp. 1125-1132
    • Shulman, N.1    Zolopa, A.R.2    Passaro, D.3    Shafer, R.W.4    Huang, W.5    Katzenstein, D.6
  • 24
    • 18344409610 scopus 로고    scopus 로고
    • The clinical relevance of non-nucleoside reverse transcriptase inhibitor hypersusceptibility: A prospective cohort analysis
    • Haubrich RH, Kemper CA, Hellmann NS, Keiser PH, Witt MD, Forthal DN, et al.: The clinical relevance of non-nucleoside reverse transcriptase inhibitor hypersusceptibility: A prospective cohort analysis. AIDS 2002;16:F33-40.
    • (2002) AIDS , vol.16
    • Haubrich, R.H.1    Kemper, C.A.2    Hellmann, N.S.3    Keiser, P.H.4    Witt, M.D.5    Forthal, D.N.6
  • 25
    • 0037131303 scopus 로고    scopus 로고
    • Hypersusceptibility to non-nucleoside reverse transcriptase inhibitors in HIV-1: Clinical, phenotypic and genotypic correlates
    • Whitcomb JM, Huang W, Limoli K, Paxinos E, Wrin T, Skowron G, et al.: Hypersusceptibility to non-nucleoside reverse transcriptase inhibitors in HIV-1: Clinical, phenotypic and genotypic correlates. AIDS 2002;16:F41-47.
    • (2002) AIDS , vol.16
    • Whitcomb, J.M.1    Huang, W.2    Limoli, K.3    Paxinos, E.4    Wrin, T.5    Skowron, G.6
  • 26
    • 0030816830 scopus 로고    scopus 로고
    • A recombinant retroviral system for rapid in vivo analysis of human immunodeficiency virus type 1 susceptibility to reverse transcriptase inhibitors
    • Shi C and Mellors JW: A recombinant retroviral system for rapid in vivo analysis of human immunodeficiency virus type 1 susceptibility to reverse transcriptase inhibitors. Antimicrob Agents Chemother 1997;41:2781-2785.
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 2781-2785
    • Shi, C.1    Mellors, J.W.2
  • 27
    • 0022495870 scopus 로고
    • Production of acquired immunodeficiency syndrome-associated retrovirus in human and non-human cells transfected with an infectious molecular clone
    • Adachi A, Gendelman E, Koenig S, Folks T, Willey R, Rabson A, et al.: Production of acquired immunodeficiency syndrome-associated retrovirus in human and non-human cells transfected with an infectious molecular clone. J Virol 1986;59:284-291.
    • (1986) J Virol , vol.59 , pp. 284-291
    • Adachi, A.1    Gendelman, E.2    Koenig, S.3    Folks, T.4    Willey, R.5    Rabson, A.6
  • 30
    • 0242363243 scopus 로고    scopus 로고
    • Relationship between in vitro human immunodeficiency virus type 1 replication rate and virus load in plasma
    • Campbell TB, Schneider K, Wrin T, Petropoulos CJ, and Connick E: Relationship between in vitro human immunodeficiency virus type 1 replication rate and virus load in plasma. J Virol 2003;77:12105-12112.
    • (2003) J Virol , vol.77 , pp. 12105-12112
    • Campbell, T.B.1    Schneider, K.2    Wrin, T.3    Petropoulos, C.J.4    Connick, E.5
  • 31
    • 0035811838 scopus 로고    scopus 로고
    • Impact of clinical reverse transcriptase sequences on the replication capacity of HIV-1 drug-resistant mutants
    • Dykes C, Fox K, Lloyd A, Chiulli M, Morse E, and Demeter LM: Impact of clinical reverse transcriptase sequences on the replication capacity of HIV-1 drug-resistant mutants. Virology 2001;285:193-203.
    • (2001) Virology , vol.285 , pp. 193-203
    • Dykes, C.1    Fox, K.2    Lloyd, A.3    Chiulli, M.4    Morse, E.5    Demeter, L.M.6
  • 32
    • 2942560805 scopus 로고    scopus 로고
    • The impact of the M184V substitution on drug resistance and viral fitness
    • Wainberg MA: The impact of the M184V substitution on drug resistance and viral fitness. Expert Rev Anti Infect Ther 2004;2:147-151.
    • (2004) Expert Rev Anti Infect Ther , vol.2 , pp. 147-151
    • Wainberg, M.A.1
  • 33
    • 0037223722 scopus 로고    scopus 로고
    • Amino acid substitutions at position 190 of human immunodeficiency virus type 1 reverse transcriptase increase susceptibility to delavirdine and impair virus replication
    • Huang W, Gamarnik A, Limoli K, Petropoulos CJ, and Whitcomb JM: Amino acid substitutions at position 190 of human immunodeficiency virus type 1 reverse transcriptase increase susceptibility to delavirdine and impair virus replication. J Virol 2003;77:1512-1523.
    • (2003) J Virol , vol.77 , pp. 1512-1523
    • Huang, W.1    Gamarnik, A.2    Limoli, K.3    Petropoulos, C.J.4    Whitcomb, J.M.5
  • 34
    • 0031940767 scopus 로고    scopus 로고
    • A mutation at position 190 of human immunodeficiency virus type 1 reverse transcriptase interacts with mutations at positions 74 and 75 via the template primer
    • Boyer PL, Gao HQ, and Hughes SH: A mutation at position 190 of human immunodeficiency virus type 1 reverse transcriptase interacts with mutations at positions 74 and 75 via the template primer. Antimicrob Agents Chemother 1998;42:447-452.
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 447-452
    • Boyer, P.L.1    Gao, H.Q.2    Hughes, S.H.3
  • 35
    • 4744350818 scopus 로고    scopus 로고
    • Effects of the G190A substitution of HIV reverse transcriptase on phenotypic susceptibility of patient isolates to delavirdine
    • Uhlmann EJ, Tebas P, Storch GA, Powderly WG, Lie YS, Whitcomb JM, et al.: Effects of the G190A substitution of HIV reverse transcriptase on phenotypic susceptibility of patient isolates to delavirdine. J Clin Virol 2004;31:198-203.
    • (2004) J Clin Virol , vol.31 , pp. 198-203
    • Uhlmann, E.J.1    Tebas, P.2    Storch, G.A.3    Powderly, W.G.4    Lie, Y.S.5    Whitcomb, J.M.6
  • 36
    • 17444388859 scopus 로고    scopus 로고
    • Rare mutations at codon 103 of HIV-1 reverse transcriptase can confer resistance to non-nucleoside reverse transcriptase inhibitors
    • Harrigan PR, Mo T, Wynhoven B, Hirsch J, Brumme Z, McKenna P, et al.: Rare mutations at codon 103 of HIV-1 reverse transcriptase can confer resistance to non-nucleoside reverse transcriptase inhibitors. AIDS 2005;19:549-554.
    • (2005) AIDS , vol.19 , pp. 549-554
    • Harrigan, P.R.1    Mo, T.2    Wynhoven, B.3    Hirsch, J.4    Brumme, Z.5    McKenna, P.6
  • 37
    • 0000770125 scopus 로고    scopus 로고
    • Effects of M41L and T215Y mutations in HIV-1 reverse transcriptase on removal of chain-terminators from blocked primer/templates
    • Meyer PR, Pfeifer I, Matsuura S, and Scott WA: Effects of M41L and T215Y mutations in HIV-1 reverse transcriptase on removal of chain-terminators from blocked primer/templates. Antiviral Ther 2000;(Suppl. 3):14.
    • (2000) Antiviral Ther , Issue.SUPPL. 3 , pp. 14
    • Meyer, P.R.1    Pfeifer, I.2    Matsuura, S.3    Scott, W.A.4
  • 38
    • 0035984790 scopus 로고    scopus 로고
    • ATP-dependent removal of nucleoside reverse transcriptase inhibitors by human immunodeficiency virus type 1 reverse transcriptase
    • Naeger LK, Margot NA, and Miller MD: ATP-dependent removal of nucleoside reverse transcriptase inhibitors by human immunodeficiency virus type 1 reverse transcriptase. Antimicrob Agents Chemother 2002;46:2179-2184.
    • (2002) Antimicrob Agents Chemother , vol.46 , pp. 2179-2184
    • Naeger, L.K.1    Margot, N.A.2    Miller, M.D.3
  • 39
    • 21844450214 scopus 로고    scopus 로고
    • Antiviral activity of lamivudine in salvage therapy for multi-drug resistant HIV-1 infection
    • Campbell TB, Johnson SC, Zolopa AR, Young RK, Bushman L, et al.: Antiviral activity of lamivudine in salvage therapy for multi-drug resistant HIV-1 infection. Clin Infect Dis 2005;41:236-242.
    • (2005) Clin Infect Dis , vol.41 , pp. 236-242
    • Campbell, T.B.1    Johnson, S.C.2    Zolopa, A.R.3    Young, R.K.4    Bushman, L.5
  • 40
    • 0033165851 scopus 로고    scopus 로고
    • A mechanism of AZT resistance: An increase in nucleotide-dependent primer unblocking by mutant HIV-1 reverse transcriptase
    • Meyer PR, Matsuura SE, Mian AM, So AG, and Scott WA: A mechanism of AZT resistance: An increase in nucleotide-dependent primer unblocking by mutant HIV-1 reverse transcriptase. Mol Cell 1999;4:35-43.
    • (1999) Mol Cell , vol.4 , pp. 35-43
    • Meyer, P.R.1    Matsuura, S.E.2    Mian, A.M.3    So, A.G.4    Scott, W.A.5
  • 41
    • 0035031936 scopus 로고    scopus 로고
    • Selective excision of AZTMP by drug-resistant human immunodeficiency virus reverse transcriptase
    • Boyer PL, Sarafianos SG, Arnold E, and Hughes SH: Selective excision of AZTMP by drug-resistant human immunodeficiency virus reverse transcriptase. J Virol 2001;75:4832-4842.
    • (2001) J Virol , vol.75 , pp. 4832-4842
    • Boyer, P.L.1    Sarafianos, S.G.2    Arnold, E.3    Hughes, S.H.4
  • 42
    • 0242354002 scopus 로고    scopus 로고
    • Molecular impact of the M184V mutation in human immunodeficiency virus type 1 reverse transcriptase
    • Diallo K, Gotte M, and Wainberg MA: Molecular impact of the M184V mutation in human immunodeficiency virus type 1 reverse transcriptase. Antimicrob Agents Chemother 2003;47:3377-3383.
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 3377-3383
    • Diallo, K.1    Gotte, M.2    Wainberg, M.A.3
  • 43
    • 21444443785 scopus 로고    scopus 로고
    • Impaired rescue of chain-terminated DNA synthesis associated with the L74V mutation in human immunodeficiency virus type 1 reverse transcriptase
    • Frankel FA, Marchand B, Turner D, Gotte M, and Wainberg, MA: Impaired rescue of chain-terminated DNA synthesis associated with the L74V mutation in human immunodeficiency virus type 1 reverse transcriptase. Antimicrob Agents Chemother 2005;49:2657-2664.
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 2657-2664
    • Frankel, F.A.1    Marchand, B.2    Turner, D.3    Gotte, M.4    Wainberg, M.A.5
  • 44
    • 34147132711 scopus 로고    scopus 로고
    • Diminished efficiency of HIV-1 reverse transcriptase containing the K65R and M184V drug resistance mutations
    • Frankel FA, Invernizzi CF, Oliveira M, and Wainberg MA: Diminished efficiency of HIV-1 reverse transcriptase containing the K65R and M184V drug resistance mutations. AIDS 2007;21:665-675.
    • (2007) AIDS , vol.21 , pp. 665-675
    • Frankel, F.A.1    Invernizzi, C.F.2    Oliveira, M.3    Wainberg, M.A.4
  • 45
    • 33845275093 scopus 로고    scopus 로고
    • In vitro human immunodeficiency virus type 1 resistance selections with combinations of tenofovir and emtricitabine or abacavir and lamivudine
    • Margot NA, Waters JM, and Miller MD: In vitro human immunodeficiency virus type 1 resistance selections with combinations of tenofovir and emtricitabine or abacavir and lamivudine. Antimicrob Agents Chemother 2006;50:4087-4095.
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 4087-4095
    • Margot, N.A.1    Waters, J.M.2    Miller, M.D.3
  • 46
    • 0025950055 scopus 로고
    • Resistance to ddI and sensitivity to AZT induced by a mutation in HIV-1 reverse transcriptase
    • St Clair MH, Martin JL, Tudor-Williams G, Bach MC, Vavro CL, King DM, et al.: Resistance to ddI and sensitivity to AZT induced by a mutation in HIV-1 reverse transcriptase. Science 1991;253:1557-1559.
    • (1991) Science , vol.253 , pp. 1557-1559
    • St Clair, M.H.1    Martin, J.L.2    Tudor-Williams, G.3    Bach, M.C.4    Vavro, C.L.5    King, D.M.6
  • 47
    • 0030768138 scopus 로고    scopus 로고
    • Attenuated replication of human immunodeficiency virus type 1 with a didanosine-selected reverse transcriptase mutation
    • Sharma PL and Crumpacker CS: Attenuated replication of human immunodeficiency virus type 1 with a didanosine-selected reverse transcriptase mutation. J Virol 1997;71:8846-8851.
    • (1997) J Virol , vol.71 , pp. 8846-8851
    • Sharma, P.L.1    Crumpacker, C.S.2
  • 48
    • 0032875344 scopus 로고    scopus 로고
    • Decreased processivity of human immunodeficiency virus type 1 reverse transcriptase (RT) containing didanosine-selected mutation Leu74Val: A comparative analysis of RT variants Leu74Val and lamivudine-selected Met184Val
    • Sharma PL and Crumpacker CS: Decreased processivity of human immunodeficiency virus type 1 reverse transcriptase (RT) containing didanosine-selected mutation Leu74Val: A comparative analysis of RT variants Leu74Val and lamivudine-selected Met184Val. J Virol 1999;73:8448-8456.
    • (1999) J Virol , vol.73 , pp. 8448-8456
    • Sharma, P.L.1    Crumpacker, C.S.2
  • 49
    • 21444452131 scopus 로고    scopus 로고
    • The L74V mutation in human immunodeficiency virus type 1 reverse transcriptase counteracts enhanced excision of zidovudine monophosphate associated with thymidine analog resistance mutations
    • Miranda LR, Gotte M, Liang F, and Kuritzkes DR: The L74V mutation in human immunodeficiency virus type 1 reverse transcriptase counteracts enhanced excision of zidovudine monophosphate associated with thymidine analog resistance mutations. Antimicrob Agents Chemother 2005;49:2648-2656.
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 2648-2656
    • Miranda, L.R.1    Gotte, M.2    Liang, F.3    Kuritzkes, D.R.4
  • 50
    • 15144342918 scopus 로고    scopus 로고
    • Kinetics of response in lymphoid tissues to antiretroviral therapy of HIV-1 infection
    • Cavert W, Notermans DW, Staskus K, Wietgrefe SW, Zupancic M, Gebhard K, et al.: Kinetics of response in lymphoid tissues to antiretroviral therapy of HIV-1 infection. Science 1997;276:960-964.
    • (1997) Science , vol.276 , pp. 960-964
    • Cavert, W.1    Notermans, D.W.2    Staskus, K.3    Wietgrefe, S.W.4    Zupancic, M.5    Gebhard, K.6
  • 51
    • 0030070683 scopus 로고    scopus 로고
    • Selective pressure of a quinoxaline nonnucleoside inhibitor of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) on HIV-1 replication results in the emergence of nucleoside RT-inhibitor-specific (RT Leu-74→Val or Ile and Val-75→Leu or Ile) HIV-1 mutants
    • Kleim JP, Rosner M, Winkler I, Paessens A, Kirsch R, Hsiou Y, et al.: Selective pressure of a quinoxaline nonnucleoside inhibitor of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) on HIV-1 replication results in the emergence of nucleoside RT-inhibitor-specific (RT Leu-74→Val or Ile and Val-75→Leu or Ile) HIV-1 mutants. Proc Natl Acad Sci USA 1996;93:34-38.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 34-38
    • Kleim, J.P.1    Rosner, M.2    Winkler, I.3    Paessens, A.4    Kirsch, R.5    Hsiou, Y.6
  • 52
    • 0027937974 scopus 로고
    • Resistance pattern of human immunodeficiency virus type 1 reverse transcriptase to quinoxaline S-2720
    • Balzarini J, Karlsson A, Meichsner C, Paessens A, Riess G, De Clercq E, et al.: Resistance pattern of human immunodeficiency virus type 1 reverse transcriptase to quinoxaline S-2720. J Virol 1994:68:7986-7992.
    • (1994) J Virol , vol.68 , pp. 7986-7992
    • Balzarini, J.1    Karlsson, A.2    Meichsner, C.3    Paessens, A.4    Riess, G.5    De Clercq, E.6
  • 53
    • 0029745634 scopus 로고    scopus 로고
    • A drug resistance mutation in the inhibitor binding pocket of human immunodeficiency virus type 1 reverse transcriptase impairs DNA synthesis and RNA degradation
    • Fan N, Rank KB, Slade DE, Poppe SM, Evans DB, Kopta LA, et al.: A drug resistance mutation in the inhibitor binding pocket of human immunodeficiency virus type 1 reverse transcriptase impairs DNA synthesis and RNA degradation. Biochemistry 1996;35:9737-9745.
    • (1996) Biochemistry , vol.35 , pp. 9737-9745
    • Fan, N.1    Rank, K.B.2    Slade, D.E.3    Poppe, S.M.4    Evans, D.B.5    Kopta, L.A.6
  • 54
    • 0028347888 scopus 로고
    • Mutational analysis of residue 190 of human immunodeficiency virus type 1 reverse transcriptase
    • Kleim JP, Bender R, Kirsch R, Meichsner C, Paessens A, and Riess G: Mutational analysis of residue 190 of human immunodeficiency virus type 1 reverse transcriptase. Virology 1994;200:696-701.
    • (1994) Virology , vol.200 , pp. 696-701
    • Kleim, J.P.1    Bender, R.2    Kirsch, R.3    Meichsner, C.4    Paessens, A.5    Riess, G.6
  • 55
    • 0033921632 scopus 로고    scopus 로고
    • In vitro selection of mutations in the human immunodeficiency virus type 1 reverse transcriptase that decrease susceptibility to (-)-beta-D-dioxolane- guanosine and suppress resistance to 3′-azido-3′-deoxythymidine
    • Bazmi HZ, Hammond JL, Cavalcanti SC, Chu CK, Schinazi RF, and Mellors JW: In vitro selection of mutations in the human immunodeficiency virus type 1 reverse transcriptase that decrease susceptibility to (-)-beta-D-dioxolane- guanosine and suppress resistance to 3′-azido-3′-deoxythymidine. Antimicrob Agents Chemother 2000;44:1783-1788.
    • (2000) Antimicrob Agents Chemother , vol.44 , pp. 1783-1788
    • Bazmi, H.Z.1    Hammond, J.L.2    Cavalcanti, S.C.3    Chu, C.K.4    Schinazi, R.F.5    Mellors, J.W.6
  • 57
    • 34250847144 scopus 로고    scopus 로고
    • Molecular mechanisms of bidirectional antagonism between K65R and thymidine analog mutations in HIV-1 reverse transcriptase
    • Parikh UM, Zelina S, Sluis-Cremer N, and Mellors JW: Molecular mechanisms of bidirectional antagonism between K65R and thymidine analog mutations in HIV-1 reverse transcriptase. AIDS 2007;21:1405-1414.
    • (2007) AIDS , vol.21 , pp. 1405-1414
    • Parikh, U.M.1    Zelina, S.2    Sluis-Cremer, N.3    Mellors, J.W.4
  • 58
    • 33646440592 scopus 로고    scopus 로고
    • The K65R mutation in human immunodeficiency virus type 1 reverse transcriptase exhibits bidirectional phenotypic antagonism with thymidine analog mutations
    • Parikh UM, Bacheler L, Koontz D, and Mellors JW: The K65R mutation in human immunodeficiency virus type 1 reverse transcriptase exhibits bidirectional phenotypic antagonism with thymidine analog mutations. J Virol 2006;80:4971-4977.
    • (2006) J Virol , vol.80 , pp. 4971-4977
    • Parikh, U.M.1    Bacheler, L.2    Koontz, D.3    Mellors, J.W.4
  • 59
    • 9144271024 scopus 로고    scopus 로고
    • Incidence of resistance in a double-blind study comparing lopinavir/ritonavir plus stavudine and lamivudine to nelfinavir plus stavudine and lamivudine
    • Kempf DJ, King MS, Bernstein B, Cernohous P, Bauer E, Moseley J, et al.: Incidence of resistance in a double-blind study comparing lopinavir/ritonavir plus stavudine and lamivudine to nelfinavir plus stavudine and lamivudine. J Infect Dis 2004;189:51-60.
    • (2004) J Infect Dis , vol.189 , pp. 51-60
    • Kempf, D.J.1    King, M.S.2    Bernstein, B.3    Cernohous, P.4    Bauer, E.5    Moseley, J.6
  • 60
    • 0035916915 scopus 로고    scopus 로고
    • Use of genotypic resistance testing to guide HIV therapy: Clinical impact and cost-effectiveness
    • Weinstein MC, Goldie SJ, Losina E, Cohen CJ, Baxter JD, Zhang H, et al.: Use of genotypic resistance testing to guide HIV therapy: Clinical impact and cost-effectiveness. Ann Intern Med 2001;134:440-450.
    • (2001) Ann Intern Med , vol.134 , pp. 440-450
    • Weinstein, M.C.1    Goldie, S.J.2    Losina, E.3    Cohen, C.J.4    Baxter, J.D.5    Zhang, H.6
  • 61
    • 0037192551 scopus 로고    scopus 로고
    • Phenotypic or genotypic resistance testing for choosing antiretroviral therapy after treatment failure: A randomized trial
    • Meynard JL, Vray M, Morand-Joubert L, Race E, Descamps D, Peytavin G, et al.: Phenotypic or genotypic resistance testing for choosing antiretroviral therapy after treatment failure: A randomized trial. AIDS 2002;16:727-736.
    • (2002) AIDS , vol.16 , pp. 727-736
    • Meynard, J.L.1    Vray, M.2    Morand-Joubert, L.3    Race, E.4    Descamps, D.5    Peytavin, G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.