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Volumn 42, Issue 2, 1998, Pages 447-452

A mutation at position 190 of Human Immunodeficiency Virus type 1 reverse transcriptase interacts with mutations at positions 74 and 75 via the template primer

Author keywords

[No Author keywords available]

Indexed keywords

PIPERIDINE DERIVATIVE; RNA DIRECTED DNA POLYMERASE; TALVIRALINE; VIRUS ENZYME;

EID: 0031940767     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (58)

References (31)
  • 1
    • 0027937974 scopus 로고
    • Resistance pattern of human immunodeficiency virus type 1 reverse transcriptase to quinoxaline S-2720
    • Balzarini, J., A. Karlsson, C. Meichsner, A. Paessens, G. Reiss, E. de Clercq, and J.-P. Kleim. 1994. Resistance pattern of human immunodeficiency virus type 1 reverse transcriptase to quinoxaline S-2720. J. Virol. 68:7986-7992.
    • (1994) J. Virol. , vol.68 , pp. 7986-7992
    • Balzarini, J.1    Karlsson, A.2    Meichsner, C.3    Paessens, A.4    Reiss, G.5    De Clercq, E.6    Kleim, J.-P.7
  • 2
    • 0026500566 scopus 로고
    • Cassette mutagenesis of the reverse transcriptase of human immunodeficiency virus type 1
    • Boyer, P. L., A. L. Ferris, and S. H. Hughes. 1992. Cassette mutagenesis of the reverse transcriptase of human immunodeficiency virus type 1. J. Virol. 66:1031-1039.
    • (1992) J. Virol. , vol.66 , pp. 1031-1039
    • Boyer, P.L.1    Ferris, A.L.2    Hughes, S.H.3
  • 3
    • 0026496655 scopus 로고
    • Mutational analysis of the fingers domain of human immunodeficiency virus type 1 reverse transcriptase
    • Boyer, P. L., A. L. Ferris, and S. H. Hughes. 1992. Mutational analysis of the fingers domain of human immunodeficiency virus type 1 reverse transcriptase. J. Virol. 66:7533-7537.
    • (1992) J. Virol. , vol.66 , pp. 7533-7537
    • Boyer, P.L.1    Ferris, A.L.2    Hughes, S.H.3
  • 4
    • 0028341306 scopus 로고
    • Sensitivity of wild-type human immunodeficiency virus type 1 reverse transcriptase to dideoxynucleotides depends on template length; the sensitivity of drug-resistant mutants does not
    • Boyer, P. L., C. Tantillo, A. Jacobo-Molina, R. G. Nanni, J. Ding, E. Arnold, and S. H. Hughes. 1994. Sensitivity of wild-type human immunodeficiency virus type 1 reverse transcriptase to dideoxynucleotides depends on template length; the sensitivity of drug-resistant mutants does not. Proc. Natl. Acad. Sci. USA 91:4882-4886.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 4882-4886
    • Boyer, P.L.1    Tantillo, C.2    Jacobo-Molina, A.3    Nanni, R.G.4    Ding, J.5    Arnold, E.6    Hughes, S.H.7
  • 5
    • 0028020216 scopus 로고
    • Mutational analysis of the fingers and palm subdomains of human immunodeficiency virus type-1 (HIV-1) reverse transcriptase
    • Boyer, P. L., A. L. Ferris, P. Clark, J. Whitmer, P. Frank, C. Tantillo, E. A. Arnold, and S. H. Hughes. 1994. Mutational analysis of the fingers and palm subdomains of human immunodeficiency virus type-1 (HIV-1) reverse transcriptase. J. Mol. Biol. 243:472-483.
    • (1994) J. Mol. Biol. , vol.243 , pp. 472-483
    • Boyer, P.L.1    Ferris, A.L.2    Clark, P.3    Whitmer, J.4    Frank, P.5    Tantillo, C.6    Arnold, E.A.7    Hughes, S.H.8
  • 6
    • 0028925911 scopus 로고
    • Mutational sensitivity patterns define crucial residues in the palm subdomain of the reverse transcriptase of human immunodeficiency virus type 1
    • Chao, S.-F., V. L. Chan, P. Juanka, A. H. Kaplan, R. Swanstrom, and C. A. Hutchison III. 1995. Mutational sensitivity patterns define crucial residues in the palm subdomain of the reverse transcriptase of human immunodeficiency virus type 1. Nucleic Acids Res. 23:803-810.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 803-810
    • Chao, S.-F.1    Chan, V.L.2    Juanka, P.3    Kaplan, A.H.4    Swanstrom, R.5    Hutchison C.A. III6
  • 7
    • 0028952146 scopus 로고
    • HIV population dynamics in vivo: Implications for genetic variation, pathogenesis, and therapy
    • Coffin, J. M. 1995. HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapy. Science 267:483-489.
    • (1995) Science , vol.267 , pp. 483-489
    • Coffin, J.M.1
  • 8
    • 0028120730 scopus 로고
    • HIV resistance to reverse transcriptase inhibitors
    • De Clercq, E. 1994. HIV resistance to reverse transcriptase inhibitors. Biochem. Pharmacol. 47:155-169.
    • (1994) Biochem. Pharmacol. , vol.47 , pp. 155-169
    • De Clercq, E.1
  • 9
    • 0029745634 scopus 로고    scopus 로고
    • A drug resistance mutation in the inhibitor binding pocket of human immunodeficiency virus type 1 reverse transcriptase impairs DNA synthesis and RNA degradation
    • Fan, N., K. B. Rank, D. E. Slade, S. M. Poppe, D. B. Evans, L. A. Kopta, R. A. Olmstead, R. C. Thomas, W. G. Tarpley, and S. K. Sharma. 1996. A drug resistance mutation in the inhibitor binding pocket of human immunodeficiency virus type 1 reverse transcriptase impairs DNA synthesis and RNA degradation. Biochemistry 35:9737-9745.
    • (1996) Biochemistry , vol.35 , pp. 9737-9745
    • Fan, N.1    Rank, K.B.2    Slade, D.E.3    Poppe, S.M.4    Evans, D.B.5    Kopta, L.A.6    Olmstead, R.A.7    Thomas, R.C.8    Tarpley, W.G.9    Sharma, S.K.10
  • 10
    • 0344699057 scopus 로고    scopus 로고
    • Unpublished data
    • Gao, H.-Q. et al. Unpublished data.
    • Gao, H.-Q.1
  • 11
    • 0028987115 scopus 로고
    • Truncating α-helix E′ of p66 human immunodeficiency virus reverse transcriptase modulates RNase H function and impairs DNA strand transfer
    • Ghosh, M., K. J. Howard, C. E. Cameron, S. J. Benkovic, S. H. Hughes, and S. F. J. Le Grice. 1995. Truncating α-helix E′ of p66 human immunodeficiency virus reverse transcriptase modulates RNase H function and impairs DNA strand transfer. J. Biol. Chem. 270:7068-7076.
    • (1995) J. Biol. Chem. , vol.270 , pp. 7068-7076
    • Ghosh, M.1    Howard, K.J.2    Cameron, C.E.3    Benkovic, S.J.4    Hughes, S.H.5    Le Grice, S.F.J.6
  • 14
    • 0342524024 scopus 로고
    • Expression of soluble, enzymatically active, human immunodeficiency virus reverse transcriptase in Escherichia coli and analysis of mutants
    • Hizi, A., C. McGill, and S. H. Hughes. 1988. Expression of soluble, enzymatically active, human immunodeficiency virus reverse transcriptase in Escherichia coli and analysis of mutants. Proc. Natl. Acad. Sci. USA 85:1218-1222.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 1218-1222
    • Hizi, A.1    McGill, C.2    Hughes, S.H.3
  • 15
    • 0025831249 scopus 로고
    • Catalytic properties of the reverse transcriptases of human immunodeficiency viruses type 1 and type 2
    • Hizi, A., R. Tal, M. Shaharabany, and S. Loya. 1991. Catalytic properties of the reverse transcriptases of human immunodeficiency viruses type 1 and type 2. J. Biol. Chem. 266:6230-6239.
    • (1991) J. Biol. Chem. , vol.266 , pp. 6230-6239
    • Hizi, A.1    Tal, R.2    Shaharabany, M.3    Loya, S.4
  • 17
    • 0030586090 scopus 로고    scopus 로고
    • Structure of unliganded HIV-1 reverse transcriptase at 2.7 Å resolution: Implications of conformational changes for polymerization and inhibition mechanisms
    • Hsiou, Y., J. Ding, K. Das, A. D. Clark, Jr., S. H. Hughes, and E. Arnold. 1996. Structure of unliganded HIV-1 reverse transcriptase at 2.7 Å resolution: implications of conformational changes for polymerization and inhibition mechanisms. Structure 4:853-860.
    • (1996) Structure , vol.4 , pp. 853-860
    • Hsiou, Y.1    Ding, J.2    Das, K.3    Clark A.D., Jr.4    Hughes, S.H.5    Arnold, E.6
  • 18
    • 0344267366 scopus 로고
    • Analysis of the reverse transcriptase of human immunodeficiency virus expressed in Escherichia coli
    • W. G. Laver and G. M. Air (ed.). Academic Press, Inc., San Diego, Calif.
    • Hughes, S. H., A. Ferris, and A. Hizi. 1990. Analysis of the reverse transcriptase of human immunodeficiency virus expressed in Escherichia coli, p. 297-307. In W. G. Laver and G. M. Air (ed.), Use of X-ray crystallography in the design of antiviral agents. Academic Press, Inc., San Diego, Calif.
    • (1990) Use of X-ray Crystallography in the Design of Antiviral Agents , pp. 297-307
    • Hughes, S.H.1    Ferris, A.2    Hizi, A.3
  • 21
    • 0028347888 scopus 로고
    • Mutational analysis of residue 190 of human immunodeficiency virus type 1 reverse transcriptase
    • Kleim, J. P., R. Bender, R. Kirsch, C. Meichsner, A. Paessens, and G. Riess. 1994. Mutational analysis of residue 190 of human immunodeficiency virus type 1 reverse transcriptase. Virology 200:696-701.
    • (1994) Virology , vol.200 , pp. 696-701
    • Kleim, J.P.1    Bender, R.2    Kirsch, R.3    Meichsner, C.4    Paessens, A.5    Riess, G.6
  • 22
    • 0030070683 scopus 로고    scopus 로고
    • Selective pressure of a quinoxaline nonnucleside inhibitor of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) on HIV-1 replication results in the emergence of nucleoside RT-inhibitor specific (RT Leu-74→Val or Ile and Val-75→Leu or Ile) HIV-1 mutants
    • Kleim, J. P., M. Rosner, I. Winkler, A. Paessens, R. Kirsch, Y. Hsiou, E. Arnold, and G. Riess. 1996. Selective pressure of a quinoxaline nonnucleside inhibitor of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) on HIV-1 replication results in the emergence of nucleoside RT-inhibitor specific (RT Leu-74→Val or Ile and Val-75→Leu or Ile) HIV-1 mutants. Proc. Natl. Acad. Sci. USA 93:34-38.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 34-38
    • Kleim, J.P.1    Rosner, M.2    Winkler, I.3    Paessens, A.4    Kirsch, R.5    Hsiou, Y.6    Arnold, E.7    Riess, G.8
  • 23
    • 0030926748 scopus 로고    scopus 로고
    • In vitro selection for different mutational patterns in HIV-1 reverse transcriptase using high and low selective pressure of the nonnucleoside reverse transcriptase inhibitor HBY 097
    • Kleim, J. P., I. Winkler, M. Rosner, R. Kirsch, H. Rubsamen-Waigmann, A. Paessens, and G. Riess. 1997. In vitro selection for different mutational patterns in HIV-1 reverse transcriptase using high and low selective pressure of the nonnucleoside reverse transcriptase inhibitor HBY 097. Virology 231:112-118.
    • (1997) Virology , vol.231 , pp. 112-118
    • Kleim, J.P.1    Winkler, I.2    Rosner, M.3    Kirsch, R.4    Rubsamen-Waigmann, H.5    Paessens, A.6    Riess, G.7
  • 24
    • 0028332029 scopus 로고
    • A novel mutation (V75T) in the human immunodeficiency virus type 1 reverse transcriptase confers resistance to 2′,3′-didehydro-2′,3′-dideoxythymidine in cell culture
    • Lacey, S. F., and B. A. Larder. 1994. A novel mutation (V75T) in the human immunodeficiency virus type 1 reverse transcriptase confers resistance to 2′,3′-didehydro-2′,3′-dideoxythymidine in cell culture. Antimicrob. Agents Chemother. 38:1428-1432.
    • (1994) Antimicrob. Agents Chemother. , vol.38 , pp. 1428-1432
    • Lacey, S.F.1    Larder, B.A.2
  • 25
    • 0028855166 scopus 로고
    • Mutations in HIV-1 reverse transcriptase and protease associated with drug resistance
    • Mellors, J. W., B. A. Larder, and R. F. Schinazi. 1995. Mutations in HIV-1 reverse transcriptase and protease associated with drug resistance. Int. Antivir. News 3:8-13.
    • (1995) Int. Antivir. News , vol.3 , pp. 8-13
    • Mellors, J.W.1    Larder, B.A.2    Schinazi, R.F.3
  • 27
    • 0027278781 scopus 로고
    • Resistance of clinical isolates of human immunodeficiency virus to antiretroviral agents
    • Richman, D. D. 1993. Resistance of clinical isolates of human immunodeficiency virus to antiretroviral agents. Antimicrob. Agents Chemother. 37: 1207-1213.
    • (1993) Antimicrob. Agents Chemother. , vol.37 , pp. 1207-1213
    • Richman, D.D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.