Targeted O2 delivery by blood substitutes: in vitro arteriolar simulations of first- and second-generation products

Microvascular Research

Volumn 76, Issue 3, 2008, Pages 169-179

  Cole, Russell ^a   Vandegriff, Kim ^b   Szeri, Andrew ^a   Savas, Omer ^a   Winslow, Robert ^b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SANGART INC   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Blood substitute; Facilitated diffusion; O2 affinity; Transport simulation; Vasoconstriction

Indexed keywords

BLOOD SUBSTITUTE; HEMOGLOBIN; MACROGOL DERIVATIVE; OXYGEN; PEG HB CONJUGATE, MP4; PEG-HB CONJUGATE, MP4; POLYHEMOGLOBIN; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; ERYTHROCYTE; MATHEMATICAL MODEL; OXYGEN CONSUMPTION; OXYGEN SUPPLY; OXYGEN TRANSPORT; PRIORITY JOURNAL; SIMULATION; ANIMAL; ARTERIOLE; BIOLOGICAL MODEL; BLOOD; CATTLE; CHEMISTRY; COMPARATIVE STUDY; HUMAN; IN VITRO STUDY; KINETICS; METABOLISM; MICROCIRCULATION; PHYSIOLOGY;

BOVINAE;

ANIMALS; ARTERIOLES; BLOOD SUBSTITUTES; CATTLE; ERYTHROCYTES; HEMOGLOBINS; HUMANS; KINETICS; MICROCIRCULATION; MODELS, BIOLOGICAL; MODELS, CARDIOVASCULAR; OXYGEN; POLYETHYLENE GLYCOLS;

EID: 53649084319     PISSN: 00262862     EISSN: 10959319     Source Type: Journal    
DOI: 10.1016/j.mvr.2008.07.002     Document Type: Article

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