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Volumn 28, Issue 20, 2008, Pages 6473-6482

CTCF regulates allelic expression of Igf2 by orchestrating a promoter-polycomb repressive complex 2 intrachromosomal loop

Author keywords

[No Author keywords available]

Indexed keywords

CCCTC BINDING FACTOR; DNA BINDING PROTEIN; LYSINE; POLYCOMB GROUP PROTEIN; POLYCOMB REPRESSIVE COMPLEX 2; PROTEIN DERIVATIVE; SOMATOMEDIN B; SUZ12 PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

EID: 53549127289     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.00204-08     Document Type: Article
Times cited : (160)

References (42)
  • 1
    • 0037213555 scopus 로고    scopus 로고
    • H19 and Igf2 - enhancing the confusion?
    • Arney, K. L. 2003. H19 and Igf2 - enhancing the confusion? Trends Genet. 19:17-23.
    • (2003) Trends Genet , vol.19 , pp. 17-23
    • Arney, K.L.1
  • 2
    • 0038607921 scopus 로고    scopus 로고
    • Epigenetics: Role of germ cell imprinting
    • Bartolomei, M. S. 2003. Epigenetics: role of germ cell imprinting. Adv. Exp. Med. Biol. 518:239-245.
    • (2003) Adv. Exp. Med. Biol , vol.518 , pp. 239-245
    • Bartolomei, M.S.1
  • 3
    • 0027203606 scopus 로고
    • Epigenetic mechanisms underlying the imprinting of the mouse H19 gene
    • Bartolomei, M. S., A. L. Webber, M. E. Brunkow, and S. M. Tilghman. 1993. Epigenetic mechanisms underlying the imprinting of the mouse H19 gene. Genes Dev. 7:1663-1673.
    • (1993) Genes Dev , vol.7 , pp. 1663-1673
    • Bartolomei, M.S.1    Webber, A.L.2    Brunkow, M.E.3    Tilghman, S.M.4
  • 4
    • 0034713375 scopus 로고    scopus 로고
    • Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene
    • Bell, A. C., and G. Felsenfeld. 2000. Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene. Nature 405:482-485.
    • (2000) Nature , vol.405 , pp. 482-485
    • Bell, A.C.1    Felsenfeld, G.2
  • 5
    • 0035910395 scopus 로고    scopus 로고
    • Insulators and boundaries: Versatile regulatory elements in the eukaryotic genome
    • Bell, A. C., A. G. West, and G. Felsenfeld. 2001. Insulators and boundaries: versatile regulatory elements in the eukaryotic genome. Science 291:447-450.
    • (2001) Science , vol.291 , pp. 447-450
    • Bell, A.C.1    West, A.G.2    Felsenfeld, G.3
  • 7
    • 0037083376 scopus 로고    scopus 로고
    • Capturing chromosome conformation
    • Dekker, J., K. Rippe, M. Dekker, and N. Kleckner. 2002. Capturing chromosome conformation. Science 295:1306-1311.
    • (2002) Science , vol.295 , pp. 1306-1311
    • Dekker, J.1    Rippe, K.2    Dekker, M.3    Kleckner, N.4
  • 8
    • 0041828248 scopus 로고    scopus 로고
    • The many roles of the transcriptional regulator CTCF
    • Dunn, K. L., and J. R. Davie. 2003. The many roles of the transcriptional regulator CTCF. Biochem. Cell Biol. 81:161-167.
    • (2003) Biochem. Cell Biol , vol.81 , pp. 161-167
    • Dunn, K.L.1    Davie, J.R.2
  • 9
    • 0346887202 scopus 로고    scopus 로고
    • Mechanisms of insulator function in gene regulation and genomic imprinting
    • Engel, N., and M. S. Bartolomei. 2003. Mechanisms of insulator function in gene regulation and genomic imprinting. Int. Rev. Cytol. 232:89-127.
    • (2003) Int. Rev. Cytol , vol.232 , pp. 89-127
    • Engel, N.1    Bartolomei, M.S.2
  • 10
    • 85176631011 scopus 로고    scopus 로고
    • Feil, R., J. Walter, N. D. Allen, and W. Reik. 1994. Developmental control of allelic methylation in the imprinted mouse Igf2 and H19 genes. Development 120:2933-2943.
    • Feil, R., J. Walter, N. D. Allen, and W. Reik. 1994. Developmental control of allelic methylation in the imprinted mouse Igf2 and H19 genes. Development 120:2933-2943.
  • 11
    • 0027287437 scopus 로고
    • Genomic imprinting and gene activation in cancer
    • Feinberg, A. P. 1993. Genomic imprinting and gene activation in cancer. Nat. Genet. 4:110-113.
    • (1993) Nat. Genet , vol.4 , pp. 110-113
    • Feinberg, A.P.1
  • 12
    • 38549129312 scopus 로고    scopus 로고
    • CTCF is the master organizer of domain-wide allele-specific chromatin at the H19/Igf2 imprinted region
    • Han, L., D. H. Lee, and P. E. Szabo. 2008. CTCF is the master organizer of domain-wide allele-specific chromatin at the H19/Igf2 imprinted region. Mol. Cell. Biol. 28:1124-1135.
    • (2008) Mol. Cell. Biol , vol.28 , pp. 1124-1135
    • Han, L.1    Lee, D.H.2    Szabo, P.E.3
  • 13
    • 0034713275 scopus 로고    scopus 로고
    • CTCF mediates methylation-sensitive enhancerblocking activity at the H19/Igf2 locus
    • Hark, A. T., C. J. Schoenherr, D. J. Katz, R. S. Ingram, J. M. Levorse, and S. M. Tilghman. 2000. CTCF mediates methylation-sensitive enhancerblocking activity at the H19/Igf2 locus. Nature 405:486-489.
    • (2000) Nature , vol.405 , pp. 486-489
    • Hark, A.T.1    Schoenherr, C.J.2    Katz, D.J.3    Ingram, R.S.4    Levorse, J.M.5    Tilghman, S.M.6
  • 14
    • 0030734880 scopus 로고    scopus 로고
    • Modulation of Igf2 genomic imprinting in mice induced by 5-azacytidine, an inhibitor of DNA methylation
    • Hu, J. F., P. H. Nguyen, N. V. Pham, T. H. Vu, and A. R. Hoffman. 1997. Modulation of Igf2 genomic imprinting in mice induced by 5-azacytidine, an inhibitor of DNA methylation. Mol. Endocrinol. 11:1891-1898.
    • (1997) Mol. Endocrinol , vol.11 , pp. 1891-1898
    • Hu, J.F.1    Nguyen, P.H.2    Pham, N.V.3    Vu, T.H.4    Hoffman, A.R.5
  • 15
    • 0034644120 scopus 로고    scopus 로고
    • Functional association of CTCF with the insulator upstream of the H19 gene is parent of origin-specific and methylation-sensitive
    • Kanduri, C., V. Pant, D. Loukinov, E. Pugacheva, C. F. Qi, A. Wolffe, R. Ohlsson, and V. V. Lobanenkov. 2000. Functional association of CTCF with the insulator upstream of the H19 gene is parent of origin-specific and methylation-sensitive. Curr. Biol. 10:853-856.
    • (2000) Curr. Biol , vol.10 , pp. 853-856
    • Kanduri, C.1    Pant, V.2    Loukinov, D.3    Pugacheva, E.4    Qi, C.F.5    Wolffe, A.6    Ohlsson, R.7    Lobanenkov, V.V.8
  • 17
    • 33746063711 scopus 로고    scopus 로고
    • CTCF binding at the H19 imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to Igf2
    • Kurukuti, S., V. K. Tiwari, G. Tavoosidana, E. Pugacheva, A. Murrell, Z. Zhao, V. Lobanenkov, W. Reik, and R. Ohlsson. 2006. CTCF binding at the H19 imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to Igf2. Proc. Natl. Acad. Sci. USA 103:1068-10689.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 1068-10689
    • Kurukuti, S.1    Tiwari, V.K.2    Tavoosidana, G.3    Pugacheva, E.4    Murrell, A.5    Zhao, Z.6    Lobanenkov, V.7    Reik, W.8    Ohlsson, R.9
  • 18
  • 21
    • 3543018516 scopus 로고    scopus 로고
    • Interaction between differentially methylated regions partitions the imprinted genes Igf2 and H19 into parent-specific chromatin loops
    • Murrell, A., S. Heeson, and W. Reik. 2004. Interaction between differentially methylated regions partitions the imprinted genes Igf2 and H19 into parent-specific chromatin loops. Nat. Genet. 36:889-893.
    • (2004) Nat. Genet , vol.36 , pp. 889-893
    • Murrell, A.1    Heeson, S.2    Reik, W.3
  • 22
    • 0027285258 scopus 로고
    • Relaxation of insulin-like growth factor II gene imprinting implicated in Wilms' tumour
    • Ogawa, O., M. R. Eccles, J. Szeto, L. A. McNoe, K. Yun, M. A. Maw, P. J. Smith, and A. E. Reeve. 1993. Relaxation of insulin-like growth factor II gene imprinting implicated in Wilms' tumour. Nature 362:749-751.
    • (1993) Nature , vol.362 , pp. 749-751
    • Ogawa, O.1    Eccles, M.R.2    Szeto, J.3    McNoe, L.A.4    Yun, K.5    Maw, M.A.6    Smith, P.J.7    Reeve, A.E.8
  • 23
    • 0035451090 scopus 로고    scopus 로고
    • CTCF is a uniquely versatile transcription regulator linked to epigenetics and disease
    • Ohlsson, R., R. Renkawitz, and V. Lobanenkov. 2001. CTCF is a uniquely versatile transcription regulator linked to epigenetics and disease. Trends Genet. 17:520-527.
    • (2001) Trends Genet , vol.17 , pp. 520-527
    • Ohlsson, R.1    Renkawitz, R.2    Lobanenkov, V.3
  • 24
    • 1842505303 scopus 로고    scopus 로고
    • Mutation of a single CTCF target site within the H19 imprinting control region leads to loss of Igf2 imprinting and complex patterns of de novo methylation upon maternal inheritance
    • Pant, V., S. Kurukuti, E. Pugacheva, S. Shamsuddin, P. Mariano, R. Renkawitz, E. Klenova, V. Lobanenkov, and R. Ohlsson. 2004. Mutation of a single CTCF target site within the H19 imprinting control region leads to loss of Igf2 imprinting and complex patterns of de novo methylation upon maternal inheritance. Mol. Cell. Biol. 24:3497-3504.
    • (2004) Mol. Cell. Biol , vol.24 , pp. 3497-3504
    • Pant, V.1    Kurukuti, S.2    Pugacheva, E.3    Shamsuddin, S.4    Mariano, P.5    Renkawitz, R.6    Klenova, E.7    Lobanenkov, V.8    Ohlsson, R.9
  • 25
    • 8144230178 scopus 로고    scopus 로고
    • Suzl2 is essential for mouse development and for EZH2 histone methyltransferase activity
    • Pasini, D., A. P. Bracken, M. R. Jensen, E. Lazzerini Denchi, and K. Helin. 2004. Suzl2 is essential for mouse development and for EZH2 histone methyltransferase activity. EMBO J. 23:4061-4071.
    • (2004) EMBO J , vol.23 , pp. 4061-4071
    • Pasini, D.1    Bracken, A.P.2    Jensen, M.R.3    Lazzerini Denchi, E.4    Helin, K.5
  • 26
    • 44649186971 scopus 로고    scopus 로고
    • A complex deoxyribonucleic acid looping configuration associated with the silencing of the maternal igf2 allele
    • Qiu, X., T. H. Vu, Q. Lu, J. Q. Ling, T. Li, A. Hou, S. K. Wang, H. L. Chen, J. F. Hu, and A. R. Hoffman. 2008. A complex deoxyribonucleic acid looping configuration associated with the silencing of the maternal igf2 allele. Mol. Endocrinol. 22:1476-1488.
    • (2008) Mol. Endocrinol , vol.22 , pp. 1476-1488
    • Qiu, X.1    Vu, T.H.2    Lu, Q.3    Ling, J.Q.4    Li, T.5    Hou, A.6    Wang, S.K.7    Chen, H.L.8    Hu, J.F.9    Hoffman, A.R.10
  • 28
    • 33845320736 scopus 로고    scopus 로고
    • Epigenetic boundaries of tumour suppressor gene promoters: The CTCF connection and its role in carcinogenesis
    • Recillas-Targa, F., I. A. De La Rosa-Velazquez, E. Soto-Reyes, and L. Benitez-Bribiesca. 2006. Epigenetic boundaries of tumour suppressor gene promoters: the CTCF connection and its role in carcinogenesis. J. Cell. Mol. Med. 10:554-568.
    • (2006) J. Cell. Mol. Med , vol.10 , pp. 554-568
    • Recillas-Targa, F.1    De La Rosa-Velazquez, I.A.2    Soto-Reyes, E.3    Benitez-Bribiesca, L.4
  • 30
    • 0034114584 scopus 로고    scopus 로고
    • Mechanisms of Igf2/H19 imprinting: DNA methylation, chromatin and long-distance gene regulation
    • Sasaki, H., K. Ishihara, and R. Kato. 2000. Mechanisms of Igf2/H19 imprinting: DNA methylation, chromatin and long-distance gene regulation. J. Biochem. (Tokyo) 127:711-715.
    • (2000) J. Biochem. (Tokyo) , vol.127 , pp. 711-715
    • Sasaki, H.1    Ishihara, K.2    Kato, R.3
  • 31
    • 0026781474 scopus 로고
    • Parental imprinting: Potentially active chromatin of the repressed maternal allele of the mouse insulin-like growth factor II (Igf2) gene
    • Sasaki, H., P. A. Jones, J. R. Chaillet, S. A. Ferguson, S. C. Barton, W. Reik, and M. A. Surani. 1992. Parental imprinting: potentially active chromatin of the repressed maternal allele of the mouse insulin-like growth factor II (Igf2) gene. Genes Dev. 6:1843-1856.
    • (1992) Genes Dev , vol.6 , pp. 1843-1856
    • Sasaki, H.1    Jones, P.A.2    Chaillet, J.R.3    Ferguson, S.A.4    Barton, S.C.5    Reik, W.6    Surani, M.A.7
  • 32
    • 0037228669 scopus 로고    scopus 로고
    • CTCF maintains differential methylation at the Igf2/H19 locus
    • Schoenherr, C. J., J. M. Levorse, and S. M. Tilghman. 2003. CTCF maintains differential methylation at the Igf2/H19 locus. Nat. Genet. 33:66-69.
    • (2003) Nat. Genet , vol.33 , pp. 66-69
    • Schoenherr, C.J.1    Levorse, J.M.2    Tilghman, S.M.3
  • 33
    • 4444365791 scopus 로고    scopus 로고
    • Microdeletions in the human H19 DMR result in loss of IGF2 imprinting and Beckwith-Wiedemann syndrome
    • Sparago, A., F. Cerrato, M. Vernucci, G. B. Ferrero, M. C. Silengo, and A. Riccio. 2004. Microdeletions in the human H19 DMR result in loss of IGF2 imprinting and Beckwith-Wiedemann syndrome. Nat. Genet. 36:958-960.
    • (2004) Nat. Genet , vol.36 , pp. 958-960
    • Sparago, A.1    Cerrato, F.2    Vernucci, M.3    Ferrero, G.B.4    Silengo, M.C.5    Riccio, A.6
  • 34
    • 2442716497 scopus 로고    scopus 로고
    • Role of CTCF binding sites in the Igf2/H19 imprinting control region
    • Szabo, P. E., S.-H. Tang, F. J. Silva, W. M. Tsark, and J. R. Mann. 2004. Role of CTCF binding sites in the Igf2/H19 imprinting control region. Mol. Cell. Biol. 24:4791-4800.
    • (2004) Mol. Cell. Biol , vol.24 , pp. 4791-4800
    • Szabo, P.E.1    Tang, S.-H.2    Silva, F.J.3    Tsark, W.M.4    Mann, J.R.5
  • 35
    • 0032419812 scopus 로고    scopus 로고
    • Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2
    • Thorvaldsen, J. L., K. L. Duran, and M. S. Bartolomei. 1998. Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2. Genes Dev. 12:3693-3702.
    • (1998) Genes Dev , vol.12 , pp. 3693-3702
    • Thorvaldsen, J.L.1    Duran, K.L.2    Bartolomei, M.S.3
  • 36
    • 0141673489 scopus 로고    scopus 로고
    • CTCF binding at the insulin-like growth factor-II (IGF2)/H19 imprinting control region is insufficient to regulate IGF2/H19 expression in human tissues
    • Ulaner, G. A., Y. Yang, J. F. Hu, T. Li, T. H. Vu, and A. R. Hoffman. 2003. CTCF binding at the insulin-like growth factor-II (IGF2)/H19 imprinting control region is insufficient to regulate IGF2/H19 expression in human tissues. Endocrinology 144:4420-4426.
    • (2003) Endocrinology , vol.144 , pp. 4420-4426
    • Ulaner, G.A.1    Yang, Y.2    Hu, J.F.3    Li, T.4    Vu, T.H.5    Hoffman, A.R.6
  • 37
    • 0027945263 scopus 로고
    • Promoter-specific imprinting of the human insulin-like growth factor-II gene
    • Vu, T. H., and A. R. Hoffman. 1994. Promoter-specific imprinting of the human insulin-like growth factor-II gene. Nature 371:714-717.
    • (1994) Nature , vol.371 , pp. 714-717
    • Vu, T.H.1    Hoffman, A.R.2
  • 38
    • 0036467996 scopus 로고    scopus 로고
    • Insulators: Many functions, many mechanisms
    • West, A. G., M. Gaszner, and G. Felsenfeld. 2002. Insulators: many functions, many mechanisms. Genes Dev. 16:271-288.
    • (2002) Genes Dev , vol.16 , pp. 271-288
    • West, A.G.1    Gaszner, M.2    Felsenfeld, G.3
  • 39
    • 0034659265 scopus 로고    scopus 로고
    • Transcriptional control: Imprinting insulation
    • Wolffe, A. P. 2000. Transcriptional control: imprinting insulation. Curr. Biol. 10:R463-R465.
    • (2000) Curr. Biol , vol.10
    • Wolffe, A.P.1
  • 40
    • 0344154456 scopus 로고    scopus 로고
    • Epigenetic regulation of Igf2/H19 imprinting at CTCF insulator binding sites
    • Yang, Y., J. F. Hu, G. Ulner, T. Li, X. Yao, T. H. Vu, and A. R. Hoffman. 2003. Epigenetic regulation of Igf2/H19 imprinting at CTCF insulator binding sites. J. Cell. Biochem. 90:1038-1055.
    • (2003) J. Cell. Biochem , vol.90 , pp. 1038-1055
    • Yang, Y.1    Hu, J.F.2    Ulner, G.3    Li, T.4    Yao, X.5    Vu, T.H.6    Hoffman, A.R.7


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