Synthesis of antiproliferative cephalotaxus esters and their evaluation against several human hematopoietic and solid tumor cell lines: Uncovering differential susceptibilities to multidrug resistance

Chemistry - A European Journal

Volumn 14, Issue 14, 2008, Pages 4293-4306

  Eckelbarger, Joseph D ^b   Wilmot, Jeremy T ^a   Epperson, Matthew T ^b   Thakur, Chandar S ^a   Shum, David ^a   Antczak, Christophe ^a   Tarassishin, Leonid ^a   Djaballah, Hakim ^a   Gin, David Y ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Alkaloids; Antitumor agents; Multidrug resistance; Total synthesis

Indexed keywords

CELL CULTURE; COMPLEXATION; DRUG PRODUCTS; ESTERIFICATION; ESTERS; ORGANIC COMPOUNDS; RAW MATERIALS; TUMORS;

ALKALOIDS; ANTITUMOR AGENTS; MULTIDRUG RESISTANCE; TOTAL SYNTHESIS;

SYNTHESIS (CHEMICAL);

ANTINEOPLASTIC AGENT; AZIRIDINE DERIVATIVE; BENZAZEPINE DERIVATIVE; CEPHALOTAXINE; ESTER; HARRINGTONINE DERIVATIVE;

ARTICLE; BLOOD DISEASE; CHEMISTRY; DRUG RESISTANCE; DRUG SCREENING; HUMAN; RETINOBLASTOMA; SYNTHESIS; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; AZIRIDINES; BENZAZEPINES; CELL LINE, TUMOR; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; ESTERS; HARRINGTONINES; HEMATOLOGIC NEOPLASMS; HUMANS; RETINOBLASTOMA;

EID: 53549115892     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.200701998     Document Type: Article

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