A novel formal total synthesis of cephalotaxine

Journal of Organic Chemistry

Volumn 70, Issue 8, 2005, Pages 3277-3280

  Li, Wei Dong Z ^a,b   Ma, Bao Chun ^a  

^a LANZHOU UNIVERSITY   (China)

^b NANKAI UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; AROMATIC COMPOUNDS; KETONES; STRUCTURE (COMPOSITION); SYNTHESIS (CHEMICAL);

ALKALOIDS; CEPHALOTAXINE; PENTACYCLIC AMINO ENONE 4;

HALOGEN COMPOUNDS;

ALKALOID; CEPHALOTAXINE;

ANNULATION REACTION; ARTICLE; CEPHALOTAXUS; CYCLIZATION; DRUG STRUCTURE; DRUG SYNTHESIS; ISOMERIZATION; X RAY DIFFRACTION;

ACETONE; ALKALOIDS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; HARRINGTONINES; MOLECULAR STRUCTURE; PYRONES;

EID: 17444380057     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo048046o     Document Type: Article

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11. See Experimental Section for detailed procedures.
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22. This result would exclude the possibility that Dolby's cyclization-isomerization of 7 → 14 may proceed via compound 5 as an intermediate.
23. The chemical yields in this work will be subjected to further optimization.
24. For General Experimental Procedures see the Supporting Information of ref 2b.