Leptin gene, leptin gene polymorphisms and bodyweight in pregnant women with diabetes mellitus type I

Journal of Physiology and Pharmacology

Volumn 59, Issue SUPPL. 4, 2008, Pages 19-31

  Iciek, Rafal ^a,c   Wender Ozegowska, E ^a   Seremak Mrozikiewicz, A ^a   Drews, K ^a   Sodowski, K ^b   Pietryga, M ^a   Brazert, J ^a  

^a POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

^b MEDICAL UNIVERSITY OF SILESIA   (Poland)

^c Department of Obstetrics and Woman Diseases ^*  (Poland)

Author keywords

Body mass index (BMI); Diabetes mellitus; Leptin gene; Leptin gene receptor; Obesity

Indexed keywords

CREATININE; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN; LEPTIN; LOW DENSITY LIPOPROTEIN;

ADULT; ARTICLE; BLOOD PRESSURE; BODY MASS; BODY WEIGHT; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CREATININE CLEARANCE; DNA POLYMORPHISM; ENERGY EXPENDITURE; FEMALE; FIRST TRIMESTER PREGNANCY; GENETIC VARIABILITY; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; OBESITY; POLYMERASE CHAIN REACTION; PREGNANCY; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

BODY MASS INDEX; BODY WEIGHT; DIABETES MELLITUS, TYPE 1; FEMALE; GENOTYPE; HUMANS; LEPTIN; OBESITY; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; PREGNANCY; PREGNANCY IN DIABETICS; PROMOTER REGIONS, GENETIC; RECEPTORS, LEPTIN;

EID: 53549085419     PISSN: 08675910     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedmand JM. Positional cloning of the mouse obese gene and its human homologue. Nature 1994; 372: 425-432.
2. Montague CT, Farooqi IS, Whitehead JP et al. Congenital leptin deficiency is associated with severe early-onset obesity in humans. Nature 1997; 387: 903-8.
3. Sinha MK. Human leptin: the hormone of adipose tissue. Eur J Endocrinol 1997; 136: 461-464.
4. Zwirska-Korczala K, Adamczyk-Sowa M, Sowa P, Pilc K, Suchanek R, Pierzchala K, Namyslowski G, Misiolek M, Sodowski K, Kato I, Kuwahara A, Zabielski R. Role of leptin, ghrelin, angiotensin II and orexins in 3T3 L1 preadipocyte cells proliferation and oxidative metabolism. J Physiol Pharmacol. 2007; 58(Suppl 1): 53-64.
5. Wang TN, Huang MC, Chang WT et al. G-2548A polymorphism of the leptin gene is correlated with extreme obesity in Taiwanese aborigines. Obesity 2006; 14: 183-187.
6. Portolés O, Sorlí JV, Francés F et al. Effect of genetic variation in the leptin gene promoter and the leptin receptor gene on obesity risk in a population-based case-control study in Spain. Eur J Epidemiol 2006; 21: 605-612.
7. Duarte SF, Francischetti EA, Genelhu-Abreu V et al. Q223R leptin receptor polymorphism associated with obesity in Brazilian multiethnic subjects. Am J Hum Biol 2006; 18: 448-453.
8. Popko K, Gorska E, Wasik M et al..Frequency of distribution of leptin receptor gene polymorphism in obstructive sleep apnea patients. J Physiol Pharmacol 2007; 58(Suppl 5/Pt 2): 551-561.
9. Couce ME, Burquera B, Paresi JE, Jensen MD, Lloyd RV. Localization of leptin receptor in the human brain. Neuroendocrinology 1997; 66: 145-150.
10. Weigle DS. Leptin and other secretory products of adipocytes modulate multiple physiological functions. Ann Endocrinol 1997; 58: 132- 136.
11. Smolinska N, Siawrys G, Kaminski T, Przala J. Leptin gene and protein expression in the trophoblast and uterine tissues during early pregnancy and the oestrous cycle of pigs. J Physiol Pharmacol 2007; 58(3): 563-581.
12. Tsiotra PC, Pappa V, Raptis SA, Tsigos C. Expression of the long and short leptin receptor isoforms in peripheral blood mononuclear cells: implications for leptin's actions. Metabolism 2000; 49: 1537-1541.
13. Papadopoulos DP, Makris TK, Poulakou M et al. Human soluble leptin receptor concentration in healthy offspring of hypertensive parents. J Clin Hypertens 2006; 8: 797-802.
14. Siawrys G, Kaminski T, Smolinska N, Przala J. Expression of leptin and long form of leptin receptor genes and proteins in pituitary of cyclic and pregnant pigs. J Physiol Pharmacol 2007; 58(4): 845-857.
15. Thompson DB, Ravussin E, Bennett PH et al. Structure and sequence variation at the human leptin receptor gene in lean and obese Pima Indians. Hum Mol Genet 1997; 6: 675-679.
16. Kinalska I, Telejko B, Kinalski M. Otyłość i cukrzyca. In: Cukrzyca, J. Sieradzki (red). Gdańsk, Via Medica 2006, pp. 282- 311.
17. Chen H, Charlat O, Tartaglia LA et al. Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice. Cell 1996; 84: 491-495.
18. Clement K, Vaisse C, Lahlou N et al. A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction. Nature 1998; 392: 398-401.
19. Adkins RM, Klauser CK, Magann EF et al. Site -2548 of the leptin gene is associated with gender-specific trends in newborn size and cord leptin levels. Int J Pediatr Obes 2007: 16: 1-8.
20. de Krom M, van der Schouw YT, Hendriks J et al. Common genetic variations in CCK, leptin, and leptin receptor genes are associated with specific human eating patterns. Diabetes 2007; 56: 276-280.
21. de Silva AM, Walder KR, Boyko EJ et al. Genetic variation and obesity in Australian women: a prospective study. Obes Res 2001; 9: 733-740.
22. van der Vleuten GM, Kluijtmans LA, Hijmans A, Blom HJ, Stalenhoef AF, de Graaf J. The Gln223Arg polymorphism in the leptin receptor is associated with familial combined hyperlipidemia. Int J Obes 2006; 30: 892-898.
23. Rand L. Winchester EC, Milwood IY, Penny MA, Kessling AM. Maternal leptin receptor gene variant Gln223Arg is not associated with variation in birth weight or maternal body mass index in UK and South Asian populations. Int J Obes Relat Metab Disord 2001; 25: 753-755.
24. Rigo J, Szendei G, Rosta K et al. Leptin receptor gene polymorphisms in severely pre-eclamptic women. Gynecol Endocrinol 2006; 22: 521-525.
25. Martinez-Abundis E, Gonzalez-Ortiz M, Pascoe-Gonzalez S. Serum leptin levels and the severity of preeclampsia. Arch Gynecol Obstet 2000; 264: 71-73.
26. Stock SM, Bremme KA. Elevation of plasma leptin levels during pregnancy in normal and diabetic women. Metabolism 1998; 47: 840-843.