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Volumn 58, Issue 2, 1997, Pages 132-136

Leptin and other secretory products of adipocytes modulate multiple physiological functions

Author keywords

appetite; energy balance; obesity; satiety

Indexed keywords

LEPTIN;

EID: 0030924252     PISSN: 00034266     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (39)

References (34)
  • 1
    • 0029896530 scopus 로고    scopus 로고
    • Role of leptin in the neuroendocrine response to fasting
    • AHIMA RS, PRABAKARAM D, MANTZOROS C, et al. Role of leptin in the neuroendocrine response to fasting. Nature 1996 ; 382 : 250-2.
    • (1996) Nature , vol.382 , pp. 250-252
    • Ahima, R.S.1    Prabakaram, D.2    Mantzoros, C.3
  • 2
    • 0029953957 scopus 로고    scopus 로고
    • Leptin is a metabolic signal to the reproductive system
    • BARASH IA, CHEUNG CC, WEIGLE DS, et al. Leptin is a metabolic signal to the reproductive system. Endocrinology 1996 ; 137 : 3144-7.
    • (1996) Endocrinology , vol.137 , pp. 3144-3147
    • Barash, I.A.1    Cheung, C.C.2    Weigle, D.S.3
  • 3
    • 0029048408 scopus 로고
    • Recombinant mouse ob protein : Evidence for a peripheral signal linking adiposity and central neural networks
    • CAMPFIELD LA, SMITH FJ, GUISEZ Y, DEVOS R, BURN P. Recombinant mouse ob protein : Evidence for a peripheral signal linking adiposity and central neural networks. Science 1995 ; 269 : 546-9.
    • (1995) Science , vol.269 , pp. 546-549
    • Campfield, L.A.1    Smith, F.J.2    Guisez, Y.3    Devos, R.4    Burn, P.5
  • 4
    • 0030010388 scopus 로고    scopus 로고
    • Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin
    • CHEHAB FF, LIM ME, LU R Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin. Nature Genetics 1996 ; 12 : 318-20.
    • (1996) Nature Genetics , vol.12 , pp. 318-320
    • Chehab, F.F.1    Lim, M.E.2    Lu, R.3
  • 5
    • 13344259300 scopus 로고    scopus 로고
    • Evidence that the diabetes gene encodes the leptin receptor : Identification of a mutation in the leptin receptor gene in db/db mice
    • CHEN H, CHARLAT O, TARTAGLIA LA, et al. Evidence that the diabetes gene encodes the leptin receptor : Identification of a mutation in the leptin receptor gene in db/db mice. Cell 1996 , 84 : 491-5.
    • (1996) Cell , vol.84 , pp. 491-495
    • Chen, H.1    Charlat, O.2    Tartaglia, L.A.3
  • 6
    • 0026638667 scopus 로고
    • Adipsin and an endogenous pathway of complement from adipose cells
    • CHOY LN, ROSEN BS, SPIEGELMAN BM. Adipsin and an endogenous pathway of complement from adipose cells. J Biol Chem 1992 ; 267 : 12736-41.
    • (1992) J Biol Chem , vol.267 , pp. 12736-12741
    • Choy, L.N.1    Rosen, B.S.2    Spiegelman, B.M.3
  • 7
    • 0030007116 scopus 로고    scopus 로고
    • Novel B219/ob receptor isoforms : Possible role of leptin in hematopoiesis and reproduction
    • CIOFFI JA, SHAFER AW, ZUPANCIC TJ, et al. Novel B219/ob receptor isoforms : Possible role of leptin in hematopoiesis and reproduction. Nature Medicine 1996 ; 2 : 585-9.
    • (1996) Nature Medicine , vol.2 , pp. 585-589
    • Cioffi, J.A.1    Shafer, A.W.2    Zupancic, T.J.3
  • 9
    • 13344295079 scopus 로고    scopus 로고
    • Serum immunoreactive-leptin concentrations in normal-weight and obese humans
    • CONSIDINE RV, SINHA MK, HEIMAN ML, et al. Serum immunoreactive-leptin concentrations in normal-weight and obese humans. N Engl J Med 1996 , 334 : 292-5.
    • (1996) N Engl J Med , vol.334 , pp. 292-295
    • Considine, R.V.1    Sinha, M.K.2    Heiman, M.L.3
  • 10
    • 0023663615 scopus 로고
    • Adipsin A circulating serine protease homolog secreted by adipose tissue and sciatic nerve
    • COOK KS, MIN HY, JOHNSON D, et al. Adipsin A circulating serine protease homolog secreted by adipose tissue and sciatic nerve. Science 1987 ; 237 : 402-4.
    • (1987) Science , vol.237 , pp. 402-404
    • Cook, K.S.1    Min, H.Y.2    Johnson, D.3
  • 11
    • 0028034207 scopus 로고
    • Differentiation of preadipose cells : Paracrine role of prostacyclin upon stimulation of adipose cells by angiotenssn-II
    • DARIMONT C, VASSAUX G, AILHAUD G, NEGREL R. Differentiation of preadipose cells : Paracrine role of prostacyclin upon stimulation of adipose cells by angiotenssn-II. Endocrinology 1994 ; 135 : 2030-6.
    • (1994) Endocrinology , vol.135 , pp. 2030-2036
    • Darimont, C.1    Vassaux, G.2    Ailhaud, G.3    Negrel, R.4
  • 12
    • 0029021599 scopus 로고
    • Induction of ob gene expression by corticosteroids is accompanied by body weight loss and reduced food intake
    • DE VOS P, SALADIN R, AUWERX J, STAELS B. Induction of ob gene expression by corticosteroids is accompanied by body weight loss and reduced food intake. J Biol Chem 1995 ; 270 : 15958-61.
    • (1995) J Biol Chem , vol.270 , pp. 15958-15961
    • De Vos, P.1    Saladin, R.2    Auwerx, J.3    Staels, B.4
  • 13
    • 0029946644 scopus 로고    scopus 로고
    • Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y
    • ERICKSON JC, CLEGG KE, PALMITER RD. Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y. Nature 1996 ; 381 : 415-8.
    • (1996) Nature , vol.381 , pp. 415-418
    • Erickson, J.C.1    Clegg, K.E.2    Palmiter, R.D.3
  • 15
    • 0029863684 scopus 로고    scopus 로고
    • Endotoxin and cytokines induce expression of leptin, the ob gene product, in hamsters. A role for leptin in the anorexia of infection
    • GRUNFELD C, ZHAO C, FULLER J, et al. Endotoxin and cytokines induce expression of leptin, the ob gene product, in hamsters. A role for leptin in the anorexia of infection. J Clin Invest 1996 ; 97 : 2152-7
    • (1996) J Clin Invest , vol.97 , pp. 2152-2157
    • Grunfeld, C.1    Zhao, C.2    Fuller, J.3
  • 16
    • 0029073613 scopus 로고
    • Weight-reducing effects of the plasma protein encoded by the obese gene
    • HALAAS JL, GAJIWALA KS, MAFFEI M, et al. Weight-reducing effects of the plasma protein encoded by the obese gene. Science 1995 ; 269 : 543-6.
    • (1995) Science , vol.269 , pp. 543-546
    • Halaas, J.L.1    Gajiwala, K.S.2    Maffei, M.3
  • 17
    • 0029083859 scopus 로고
    • Increased obese mRNA expression in omental fat cells from massively obese humans
    • HAMILTON BS, PAGLIA D, KWAN AYM, DEITEL M. Increased obese mRNA expression in omental fat cells from massively obese humans. Nature Medicine 1995 ; 1 : 953-6.
    • (1995) Nature Medicine , vol.1 , pp. 953-956
    • Hamilton, B.S.1    Paglia, D.2    Kwan, A.Y.M.3    Deitel, M.4
  • 18
    • 0028849084 scopus 로고
    • The mouse obese gene. Genomic organization, promoter activity, and activation by CCAAT/enhancer-binding protein a
    • HE Y, CHEN H, QUON MJ, REITMAN M. The mouse obese gene. Genomic organization, promoter activity, and activation by CCAAT/enhancer-binding protein a. J Biol Chem 1995 ; 270 : 28887-91
    • (1995) J Biol Chem , vol.270 , pp. 28887-28891
    • He, Y.1    Chen, H.2    Quon, M.J.3    Reitman, M.4
  • 19
    • 0027459878 scopus 로고
    • Adipose expression of tumor necrosis factor-alpha : Direct role in obesity-linked insulin resistance
    • HOTAMISLIGIL GS, SHARGILL NS, SPIEGELMAN BM. Adipose expression of tumor necrosis factor-alpha : Direct role in obesity-linked insulin resistance. Science 1993 ; 259 : 87-91.
    • (1993) Science , vol.259 , pp. 87-91
    • Hotamisligil, G.S.1    Shargill, N.S.2    Spiegelman, B.M.3
  • 20
    • 0028863211 scopus 로고
    • Structural organization and chromosomal assignment of the human obese gene
    • ISSE N, OGAWA Y, TAMURA N, et al. Structural organization and chromosomal assignment of the human obese gene. J Biol Chem 1995 ; 270 : 27728-33.
    • (1995) J Biol Chem , vol.270 , pp. 27728-27733
    • Isse, N.1    Ogawa, Y.2    Tamura, N.3
  • 21
    • 0029894050 scopus 로고    scopus 로고
    • Antidiabetic thiazolidinediones inhibit leptin (ob) gene expression in 3T3-L1 adipocytes
    • KALLEN CB, LAZAR MA. Antidiabetic thiazolidinediones inhibit leptin (ob) gene expression in 3T3-L1 adipocytes. Proc Natl Acad Sci USA 1996 ; 93 . 5793-6.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 5793-5796
    • Kallen, C.B.1    Lazar, M.A.2
  • 22
    • 0030039272 scopus 로고    scopus 로고
    • Abnormal splicing of the leptin receptor in diabetic mice
    • LEE G-H, PROENCA R, MONTEZ JM, et al. Abnormal splicing of the leptin receptor in diabetic mice. Nature 1996 ; 579 : 632-5.
    • (1996) Nature , vol.579 , pp. 632-635
    • Lee, G.-H.1    Proenca, R.2    Montez, J.M.3
  • 23
    • 0028845877 scopus 로고
    • Leptin levels in human and rodent . Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects
    • MAFFEI M, HALAAS J, RAVUSSIN E, et al. Leptin levels in human and rodent . Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects Nature Medicine 1995 ; 1 : 1155-61.
    • (1995) Nature Medicine , vol.1 , pp. 1155-1161
    • Maffei, M.1    Halaas, J.2    Ravussin, E.3
  • 24
    • 85047675409 scopus 로고    scopus 로고
    • Radioimmunological measurement of leptin in plasma of obese and diabetic human subjects
    • MCGREGOR GP, DESAGA JF, EHLENZ K, et al. Radioimmunological measurement of leptin in plasma of obese and diabetic human subjects. Endocrinology 1996 ; 137 : 1501-1504.
    • (1996) Endocrinology , vol.137 , pp. 1501-1504
    • Mcgregor, G.P.1    Desaga, J.F.2    Ehlenz, K.3
  • 25
    • 0029972928 scopus 로고    scopus 로고
    • The adipocyte specific transcription factor C/EBP alpha modulates human ob gene expression
    • MILLER SG, DE VOS P, GUERRE-MILLO M, et al. The adipocyte specific transcription factor C/EBP alpha modulates human ob gene expression. Proc Natl Acad Sci USA 1996 ; 93 : 5507-11.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 5507-5511
    • Miller, S.G.1    De Vos, P.2    Guerre-Millo, M.3
  • 26
    • 0029066265 scopus 로고
    • Effects of the obese gene product on body weight regulation in ob/ob mice
    • PELLEYMOUNTER MA, CULLEN MJ, BAKER MB, et al. Effects of the obese gene product on body weight regulation in ob/ob mice. Science 1995 ; 269 : 540-3.
    • (1995) Science , vol.269 , pp. 540-543
    • Pelleymounter, M.A.1    Cullen, M.J.2    Baker, M.B.3
  • 27
    • 0029157428 scopus 로고
    • Transient increase in obese gene expression after food intake or insulin administration
    • SALADIN R, DE VOS P, GUERRE-MILLO M, et al. Transient increase in obese gene expression after food intake or insulin administration. Nature 1995 ; 377 : 527-9.
    • (1995) Nature , vol.377 , pp. 527-529
    • Saladin, R.1    De Vos, P.2    Guerre-Millo, M.3
  • 28
    • 13344280346 scopus 로고    scopus 로고
    • Specific of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice
    • SCHWARTZ MW, BASKIN DG, BUKOWSKI TR, et al. Specific of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice. Diabetes 1996 ; 45 : 531-5.
    • (1996) Diabetes , vol.45 , pp. 531-535
    • Schwartz, M.W.1    Baskin, D.G.2    Bukowski, T.R.3
  • 29
    • 0029881125 scopus 로고    scopus 로고
    • Cerebrospinal fluid leptin levels : Relationship to plasma levels and to adiposity in humans
    • SCHWARTZ MW, PESKIND E, RASKIND M, BOYKO EJ, PORTE D Jr. Cerebrospinal fluid leptin levels : Relationship to plasma levels and to adiposity in humans. Nature Medicine 1996 ; 2 : 589-93.
    • (1996) Nature Medicine , vol.2 , pp. 589-593
    • Schwartz, M.W.1    Peskind, E.2    Raskind, M.3    Boyko, E.J.4    Porte Jr., D.5
  • 30
    • 0029098589 scopus 로고
    • The role of neuropeptide Y in the antiobesity action of the obese gene product
    • STEPHENS TW, BASINSKI M, BRISTOW PK, et al. The role of neuropeptide Y in the antiobesity action of the obese gene product. Nature 1995 ; 377 : 530-2.
    • (1995) Nature , vol.377 , pp. 530-532
    • Stephens, T.W.1    Basinski, M.2    Bristow, P.K.3
  • 31
    • 2442654859 scopus 로고
    • Identification and expression cloning of a leptin receptor, OB-R
    • TARTAGLIA LA, DEMBSKI M, WENG X, et al. Identification and expression cloning of a leptin receptor, OB-R. Cell 1995 , 83 : 1263-71.
    • (1995) Cell , vol.83 , pp. 1263-1271
    • Tartaglia, L.A.1    Dembski, M.2    Weng, X.3
  • 32
    • 0028297731 scopus 로고
    • Appetite and the regulation of body composition
    • WEIGLE DS. Appetite and the regulation of body composition. FASEB J 1994 ; 8 : 302-10.
    • (1994) FASEB J , vol.8 , pp. 302-310
    • Weigle, D.S.1
  • 33
    • 0028825577 scopus 로고
    • Recombinant ob protein reduces feeding and body weight in the ob/ob mouse
    • WEIGLE DS, BUKOWSKI TR, FOSTER DC, et al. Recombinant ob protein reduces feeding and body weight in the ob/ob mouse. J Clin Invest 1995 ; 96 : 2065-70.
    • (1995) J Clin Invest , vol.96 , pp. 2065-2070
    • Weigle, D.S.1    Bukowski, T.R.2    Foster, D.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.