In vivo attenuation of recombinant murine gammaherpesvirus 68 (MHV-68) is due to the expression and immunogenicity but not to the insertion of foreign sequences

Virology

Volumn 380, Issue 2, 2008, Pages 322-327

  El Gogo, Susanne ^a   Flach, Britta ^b,d   Staib, Caroline ^a   Sutter, Gerd ^c   Adler, Heiko ^d  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^c PAUL EHRLICH INSTITUT   (Germany)

^d INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

BAC; In vivo attenuation; Insertion of foreign sequences; Recombinant MHV 68

Indexed keywords

ANTIGEN; NONSTRUCTURAL PROTEIN 3;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATTENUATION; BIOLOGY; CONTROLLED STUDY; FEMALE; GENE TARGETING; GENE VECTOR; GENOMICS; HEPATITIS C VIRUS; HERPES VIRUS; IMMUNE RESPONSE; IMMUNOGENICITY; IN VIVO STUDY; MARKER GENE; MOUSE; MURINE GAMMAHERPESVIRUS 68; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPORTER GENE; VIRUS INFECTION; VIRUS RECOMBINANT;

ANIMALS; FEMALE; GENE EXPRESSION; HEPATITIS C ANTIBODIES; LUNG; MICE; MICE, INBRED C57BL; MUTAGENESIS, INSERTIONAL; RECOMBINATION, GENETIC; RHADINOVIRUS; SPLEEN; VIRAL NONSTRUCTURAL PROTEINS;

HEPATITIS C VIRUS; HERPESVIRIDAE; MURINAE; MURINE HEPATITIS VIRUS;

EID: 53449096923     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2008.07.034     Document Type: Article

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