Genetic deletion of synapsin II reduces neuropathic pain due to reduced glutamate but increased GABA in the spinal cord dorsal horn

Pain

Volumn 139, Issue 3, 2008, Pages 632-643

  Schmidtko, Achim ^a   Luo, Ceng ^b   Gao, Wei ^a   Geisslinger, Gerd ^a   Kuner, Rohini ^b   Tegeder, Irmgard ^a  

^a UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Glutamate; Nerve injury; Spinal cord; Synaptic vesicle protein; Vesicular glutamate transporter

Indexed keywords

4 AMINOBUTYRIC ACID; CALCIUM; CAPSAICIN; GLUTAMIC ACID; SYNAPSIN II; VESICULAR GLUTAMATE TRANSPORTER 1; VESICULAR GLUTAMATE TRANSPORTER 2;

ADAPTATION; ALLODYNIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR CHANGE; CALCIUM SIGNALING; COLD STRESS; CONTROLLED STUDY; GENE DELETION; GENETIC REGULATION; KNOCKOUT MOUSE; MECHANICAL STIMULATION; MOUSE; MUSCLE SPINDLE AFFERENT NERVE; NERVE CONDUCTION; NERVE INJURY; NEUROPATHIC PAIN; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCIATIC NERVE; SPINAL CORD; SPINAL CORD DORSAL HORN; STRAIN DIFFERENCE; SYNAPTIC TRANSMISSION; WILD TYPE;

ACTIVATING TRANSCRIPTION FACTOR 3; ADENOSINE TRIPHOSPHATE; AFFERENT PATHWAYS; ANIMALS; CALCIUM SIGNALING; CAPSAICIN; FEMALE; GAMMA-AMINOBUTYRIC ACID; GLUTAMIC ACID; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICRODIALYSIS; POSTERIOR HORN CELLS; SCIATIC NERVE; SCIATICA; SPINAL CORD; SYNAPSINS;

EID: 53349177461     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pain.2008.06.018     Document Type: Article

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