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Volumn 24, Issue 14, 2004, Pages 3711-3720

Molecular Determinants of Synapsin Targeting to Presynaptic Terminals

Author keywords

Localization; Presynaptic; Presynaptic localization; Synapsin; Synaptic transmission; Synaptic vesicle trafficking; Synaptic vesicles; Vesicle pools

Indexed keywords

GREEN FLUORESCENT PROTEIN; ISOPROTEIN; SYNAPSIN;

EID: 1842681995     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5225-03.2004     Document Type: Article
Times cited : (119)

References (56)
  • 1
    • 0033930208 scopus 로고    scopus 로고
    • Assembly of presynaptic active zones from cytoplasmic transport packets
    • Ahmari SE, Buchanan J, Smith SJ (2000) Assembly of presynaptic active zones from cytoplasmic transport packets. Nat Neurosci 3:445-451.
    • (2000) Nat Neurosci , vol.3 , pp. 445-451
    • Ahmari, S.E.1    Buchanan, J.2    Smith, S.J.3
  • 2
    • 0024366008 scopus 로고
    • Synaptobrevin: An integral membrane protein of 18,000 daltons present in small synaptic vesicles of rat brain
    • Baumert M, Maycox PR, Navone F, De Camilli P, Jahn R (1989) Synaptobrevin: an integral membrane protein of 18,000 daltons present in small synaptic vesicles of rat brain. EMBO J 8:379-384.
    • (1989) EMBO J , vol.8 , pp. 379-384
    • Baumert, M.1    Maycox, P.R.2    Navone, F.3    De Camilli, P.4    Jahn, R.5
  • 3
    • 0024506755 scopus 로고
    • Electrostatic and hydrophobic interactions of synapsin I and synapsin I fragments with phospholipid bilayers
    • Benfenati F, Greengard P, Brunner J, Bahler M (1989a) Electrostatic and hydrophobic interactions of synapsin I and synapsin I fragments with phospholipid bilayers. J Cell Biol 108:1851-1862.
    • (1989) J Cell Biol , vol.108 , pp. 1851-1862
    • Benfenati, F.1    Greengard, P.2    Brunner, J.3    Bahler, M.4
  • 4
    • 0024506756 scopus 로고
    • Interactions of synapsin I with small synaptic vesicles: Distinct sites in synapsin I bind to vesicle phospholipids and vesicle proteins
    • Benfenati F, Bahler M, Jahn R, Greengard P (1989b) Interactions of synapsin I with small synaptic vesicles: distinct sites in synapsin I bind to vesicle phospholipids and vesicle proteins. J Cell Biol 108:1863-1872.
    • (1989) J Cell Biol , vol.108 , pp. 1863-1872
    • Benfenati, F.1    Bahler, M.2    Jahn, R.3    Greengard, P.4
  • 8
    • 0035195395 scopus 로고    scopus 로고
    • Synapsin dispersion and reclustering during synaptic activity
    • Chi P, Greengard P, Ryan TA (2001) Synapsin dispersion and reclustering during synaptic activity. Nat Neurosci 4:1187-1193.
    • (2001) Nat Neurosci , vol.4 , pp. 1187-1193
    • Chi, P.1    Greengard, P.2    Ryan, T.A.3
  • 9
    • 0345701204 scopus 로고    scopus 로고
    • Synaptic vesicle mobilization is regulated by distinct synapsin I phosphorylation pathways at different frequencies
    • Chi P, Greengard P, Ryan TA (2003) Synaptic vesicle mobilization is regulated by distinct synapsin I phosphorylation pathways at different frequencies. Neuron 38:69-78.
    • (2003) Neuron , vol.38 , pp. 69-78
    • Chi, P.1    Greengard, P.2    Ryan, T.A.3
  • 10
    • 0029022960 scopus 로고
    • Impairment of axonal development and of synaptogenesis in hippocampal neurons of synapsin I-deficient mice
    • Chin LS, Li L, Ferreira A, Kosik KS, Greengard P (1995) Impairment of axonal development and of synaptogenesis in hippocampal neurons of synapsin I-deficient mice. Proc Natl Acad Sci USA 92:9230-9234.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 9230-9234
    • Chin, L.S.1    Li, L.2    Ferreira, A.3    Kosik, K.S.4    Greengard, P.5
  • 11
    • 0042490720 scopus 로고    scopus 로고
    • Synapsin I-associated phosphatidylinositol 3-kinase mediates synaptic vesicle delivery to the readily releasable pool
    • Cousin MA, Malladi CS, Tan TC, Raymond CR, Smillie KJ, Robinson PJ (2003) Synapsin I-associated phosphatidylinositol 3-kinase mediates synaptic vesicle delivery to the readily releasable pool. J Biol Chem 278:29065-29071.
    • (2003) J Biol Chem , vol.278 , pp. 29065-29071
    • Cousin, M.A.1    Malladi, C.S.2    Tan, T.C.3    Raymond, C.R.4    Smillie, K.J.5    Robinson, P.J.6
  • 16
    • 0036237621 scopus 로고    scopus 로고
    • The synapsins: Beyond the regulation of neurotransmitter release
    • Ferreira A, Rapoport M (2002) The synapsins: beyond the regulation of neurotransmitter release. Cell Mol Life Sci 59:589-595.
    • (2002) Cell Mol Life Sci , vol.59 , pp. 589-595
    • Ferreira, A.1    Rapoport, M.2
  • 18
    • 0034657169 scopus 로고    scopus 로고
    • Synapsin III: Developmental expression, subcellular localization, and role in axon formation
    • Ferreira A, Kao HT, Feng J, Rapoport M, Greengard P (2000) Synapsin III: developmental expression, subcellular localization, and role in axon formation. J Neurosci 20:3736-3744.
    • (2000) J Neurosci , vol.20 , pp. 3736-3744
    • Ferreira, A.1    Kao, H.T.2    Feng, J.3    Rapoport, M.4    Greengard, P.5
  • 19
    • 0026001491 scopus 로고
    • The distribution of synapsin I and synaptophysin in hippocampal neurons developing in culture
    • Fletcher TL, Cameron P, De Camilli P, Banker G (1991) The distribution of synapsin I and synaptophysin in hippocampal neurons developing in culture. J Neurosci 11:1617-1626.
    • (1991) J Neurosci , vol.11 , pp. 1617-1626
    • Fletcher, T.L.1    Cameron, P.2    De Camilli, P.3    Banker, G.4
  • 22
    • 0025273378 scopus 로고
    • Changes in the distribution of GAP-43 during the development of neuronal polarity
    • Goslin K, Schreyer DJ, Skene JH, Banker G (1990) Changes in the distribution of GAP-43 during the development of neuronal polarity. J Neurosci 10:588-602.
    • (1990) J Neurosci , vol.10 , pp. 588-602
    • Goslin, K.1    Schreyer, D.J.2    Skene, J.H.3    Banker, G.4
  • 23
    • 0027402975 scopus 로고
    • Synaptic vesicle phosphoproteins and regulation of synaptic function
    • Greengard P, Valtorta F, Czernik AJ, Benfenati F (1993) Synaptic vesicle phosphoproteins and regulation of synaptic function. Science 259:780-785.
    • (1993) Science , vol.259 , pp. 780-785
    • Greengard, P.1    Valtorta, F.2    Czernik, A.J.3    Benfenati, F.4
  • 24
    • 0021895138 scopus 로고
    • 2+ indicators with greatly improved fluorescence properties
    • 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260:3440-3450.
    • (1985) J Biol Chem , vol.260 , pp. 3440-3450
    • Grynkiewicz, G.1    Poenie, M.2    Tsien, R.Y.3
  • 29
    • 0040964284 scopus 로고    scopus 로고
    • Homo- and heterodimerization of synapsins
    • Hosaka M, Südhof TC (1999) Homo- and heterodimerization of synapsins. J Biol Chem 274:16747-16753.
    • (1999) J Biol Chem , vol.274 , pp. 16747-16753
    • Hosaka, M.1    Südhof, T.C.2
  • 30
    • 0033213603 scopus 로고    scopus 로고
    • A phospho-switch controls the dynamic association of synapsins with synaptic vesicles
    • Hosaka M, Hammer RE, Südhof TC (1999) A phospho-switch controls the dynamic association of synapsins with synaptic vesicles. Neuron 24:377-387.
    • (1999) Neuron , vol.24 , pp. 377-387
    • Hosaka, M.1    Hammer, R.E.2    Südhof, T.C.3
  • 31
    • 0029962955 scopus 로고    scopus 로고
    • PSD-95 is associated with the postsynaptic density and not with the presynaptic membrane at forebrain synapses
    • Hunt C, Schenker L, Kennedy M (1996) PSD-95 is associated with the postsynaptic density and not with the presynaptic membrane at forebrain synapses. J Neurosci 16:1380-1388.
    • (1996) J Neurosci , vol.16 , pp. 1380-1388
    • Hunt, C.1    Schenker, L.2    Kennedy, M.3
  • 32
    • 0020955120 scopus 로고
    • Synapsin I (protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation
    • Huttner WB, Schiebler W, Greengard P, De Camilli P (1983) Synapsin I (protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation. J Cell Biol 96:1374-1388.
    • (1983) J Cell Biol , vol.96 , pp. 1374-1388
    • Huttner, W.B.1    Schiebler, W.2    Greengard, P.3    De Camilli, P.4
  • 37
    • 0029829890 scopus 로고    scopus 로고
    • Site-specific phosphorylation of synapsin I by mitogen-activated protein kinase and Cdk5 and its effects on physiological functions
    • Matsubara M, Kusubata M, Ishiguro K, Uchida T, Titani K, Taniguchi H (1996) Site-specific phosphorylation of synapsin I by mitogen-activated protein kinase and Cdk5 and its effects on physiological functions. J Biol Chem 271:21108-21113.
    • (1996) J Biol Chem , vol.271 , pp. 21108-21113
    • Matsubara, M.1    Kusubata, M.2    Ishiguro, K.3    Uchida, T.4    Titani, K.5    Taniguchi, H.6
  • 38
    • 0031148577 scopus 로고    scopus 로고
    • Differential distribution of synapsin IIa and IIb mRNAs in various brain structures and the effect of chronic morphine administration on the regional expression of these isoforms
    • Matus-Leibovitch N, Nevo I, Vogel Z (1997) Differential distribution of synapsin IIa and IIb mRNAs in various brain structures and the effect of chronic morphine administration on the regional expression of these isoforms. Brain Res Mol Brain Res 45:301-316.
    • (1997) Brain Res Mol Brain Res , vol.45 , pp. 301-316
    • Matus-Leibovitch, N.1    Nevo, I.2    Vogel, Z.3
  • 39
    • 0033747186 scopus 로고    scopus 로고
    • Use of phosphosynapsin I-specific antibodies for image analysis of signal transduction in single nerve terminals
    • Menegon A, Dunlap DD, Castano F, Benfenati F, Czernik AJ, Greengard P, Valtorta F (2000) Use of phosphosynapsin I-specific antibodies for image analysis of signal transduction in single nerve terminals. J Cell Sci 113:3573-3582.
    • (2000) J Cell Sci , vol.113 , pp. 3573-3582
    • Menegon, A.1    Dunlap, D.D.2    Castano, F.3    Benfenati, F.4    Czernik, A.J.5    Greengard, P.6    Valtorta, F.7
  • 41
    • 0344875499 scopus 로고    scopus 로고
    • Synaptophysin I controls the targeting of VAMP2/synaptobrevin II to synaptic vesicles
    • Pennuto M, Bonanomi D, Benfenati F, Valtorta F (2003) Synaptophysin I controls the targeting of VAMP2/synaptobrevin II to synaptic vesicles. Mol Biol Cell 14:4909-4919.
    • (2003) Mol Biol Cell , vol.14 , pp. 4909-4919
    • Pennuto, M.1    Bonanomi, D.2    Benfenati, F.3    Valtorta, F.4
  • 44
    • 0037152598 scopus 로고    scopus 로고
    • Expression of synapsin III in nerve terminals and neurogenic regions of the adult brain
    • Pieribone VA, Porton B, Rendon B, Feng J, Greengard P, Kao HT (2002) Expression of synapsin III in nerve terminals and neurogenic regions of the adult brain. J Comp Neurol 454:105-114.
    • (2002) J Comp Neurol , vol.454 , pp. 105-114
    • Pieribone, V.A.1    Porton, B.2    Rendon, B.3    Feng, J.4    Greengard, P.5    Kao, H.T.6
  • 45
    • 0344285992 scopus 로고    scopus 로고
    • Characterization of transcripts from the synapsin III gene locus
    • Porton B, Kao HT, Greengard P (1999) Characterization of transcripts from the synapsin III gene locus. J Neurochem 73:2266-2271.
    • (1999) J Neurochem , vol.73 , pp. 2266-2271
    • Porton, B.1    Kao, H.T.2    Greengard, P.3
  • 46
    • 0032520191 scopus 로고    scopus 로고
    • Heterogeneity in the molecular composition of excitatory postsynaptic sites during development of hippocampal neurons in culture
    • Rao A, Kim E, Sheng M, Craig AM (1998) Heterogeneity in the molecular composition of excitatory postsynaptic sites during development of hippocampal neurons in culture. J Neurosci 18:1217-1229.
    • (1998) J Neurosci , vol.18 , pp. 1217-1229
    • Rao, A.1    Kim, E.2    Sheng, M.3    Craig, A.M.4
  • 47
    • 0037317392 scopus 로고    scopus 로고
    • Actin has a molecular scaffolding, not propulsive, role in presynaptic function
    • Sankaranarayanan S, Alturi PP, Ryan TA (2003) Actin has a molecular scaffolding, not propulsive, role in presynaptic function. Nat Neurosci 6:127-135.
    • (2003) Nat Neurosci , vol.6 , pp. 127-135
    • Sankaranarayanan, S.1    Alturi, P.P.2    Ryan, T.A.3
  • 48
    • 0035912750 scopus 로고    scopus 로고
    • Molecular organization of the postsynaptic specialization
    • Sheng M (2001) Molecular organization of the postsynaptic specialization. Proc Natl Acad Sci USA 98:7058-7061.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 7058-7061
    • Sheng, M.1
  • 49
    • 0030729884 scopus 로고    scopus 로고
    • Kinetic analysis of the phosphorylation-dependent interactions of synapsin I with rat brain synaptic vesicles
    • Stefani G, Onofri F, Valtorta F, Vaccaro P, Greengard P, Benfenati F (1997) Kinetic analysis of the phosphorylation-dependent interactions of synapsin I with rat brain synaptic vesicles. J Physiol (Lond) 504:501-515.
    • (1997) J Physiol (Lond) , vol.504 , pp. 501-515
    • Stefani, G.1    Onofri, F.2    Valtorta, F.3    Vaccaro, P.4    Greengard, P.5    Benfenati, F.6
  • 51
    • 0021346568 scopus 로고
    • Microspectrofluorometry by digital image processing: Measurement of cytoplasmic pH
    • Tanasugarn L, McNeil P, Reynolds GT, Taylor DL (1984) Microspectrofluorometry by digital image processing: measurement of cytoplasmic pH. J Cell Biol 98:717-724.
    • (1984) J Cell Biol , vol.98 , pp. 717-724
    • Tanasugarn, L.1    McNeil, P.2    Reynolds, G.T.3    Taylor, D.L.4
  • 52
    • 0025005797 scopus 로고
    • Synapsin II. Mapping of a domain in the NH2-terminal region which binds to small synaptic vesicles
    • Thiel G, Südhof TC, Greengard P (1990) Synapsin II. Mapping of a domain in the NH2-terminal region which binds to small synaptic vesicles. J Biol Chem 265:16527-16533.
    • (1990) J Biol Chem , vol.265 , pp. 16527-16533
    • Thiel, G.1    Südhof, T.C.2    Greengard, P.3
  • 53
    • 0023645302 scopus 로고
    • Inactivation of isocitrate dehydrogenase by phosphorylation is mediated by the negative charge of the phosphate
    • Thorsness P, Koshland Jr D (1987) Inactivation of isocitrate dehydrogenase by phosphorylation is mediated by the negative charge of the phosphate. J Biol Chem 262:10422-10425.
    • (1987) J Biol Chem , vol.262 , pp. 10422-10425
    • Thorsness, P.1    Koshland Jr., D.2
  • 54
    • 0006602702 scopus 로고
    • VAMP-1: A synaptic vesicle-associated integral membrane protein
    • Trimble WS, Cowan DM, Scheller RH (1988) VAMP-1: a synaptic vesicle-associated integral membrane protein. Proc Natl Acad Sci USA 85:4538-4542.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 4538-4542
    • Trimble, W.S.1    Cowan, D.M.2    Scheller, R.H.3
  • 55
    • 0347993101 scopus 로고    scopus 로고
    • Phosphorylation-regulated inhibition of the Gz GAP activity of RGS proteins by synapsin I
    • M309626200
    • Tu Y, Nayak SK, Woodson J, Ross EM (2003) Phosphorylation-regulated inhibition of the Gz GAP activity of RGS proteins by synapsin I. J Biol Chem:M309626200.
    • (2003) J Biol Chem
    • Tu, Y.1    Nayak, S.K.2    Woodson, J.3    Ross, E.M.4
  • 56
    • 0022391791 scopus 로고
    • Identification and localization of synaptophysin, an integral membrane glycoprotein of Mr 38,000 characteristic of presynaptic vesicles
    • Wiedenmann B, Franke WW (1985) Identification and localization of synaptophysin, an integral membrane glycoprotein of Mr 38,000 characteristic of presynaptic vesicles. Cell 41:1017-1028.
    • (1985) Cell , vol.41 , pp. 1017-1028
    • Wiedenmann, B.1    Franke, W.W.2


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