Corrigendum to "Discovery, SAR and X-ray structure of 1H-benzimidazole-5-carboxylic acid cyclohexyl-methyl-amides as inhibitors of inducible T-cell kinase (Itk)" [Bioorg. Med. Chem. Lett. 18 (2008) 5545-5549] (DOI:10.1016/j.bmcl.2008.09.015);Discovery, SAR and X-ray structure of 1H-benzimidazole-5-carboxylic acid cyclohexyl-methyl-amides as inhibitors of inducible T-cell kinase (Itk)

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 20, 2008, Pages 5545-5549

  Moriarty, Kevin J ^b   Takahashi, Hidenori ^a   Pullen, Steven S ^a   Khine, Hnin Hnin ^a   Sallati, Rosemarie H ^a   Raymond, Ernest L ^a   Woska Jr , Joseph R ^a   Jeanfavre, Deborah D ^a   Roth, Gregory P ^c   Winters, Michael P ^b   Qiao, Lei ^b   Ryan, Declan ^b   DesJarlais, Renee ^b   Robinson, Darius ^b   Wilson, Matthew ^b   Bobko, Mark ^b   Cook, Brian N ^a   Lo, Ho Yin ^a   Nemoto, Peter A ^a   Kashem, Mohammed A ^a   Wolak, John P ^a   White, André ^a   Magolda, Ronald L ^a   Tomczuk, Bruce ^b   more..

^a BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

^b PRDUS LLC   (United States)

^c Burnham Institute for Medical Research at Lake Nona   (United States)

Author keywords

Benzimidazole; Inhibitor; Itk; SAR

Indexed keywords

1H BENZIMIDAZOLE 5 CARBOXYLIC ACID CYCLOHEXYLMETHYLAMIDE; INDUCIBLE T CELL KINASE; PHOSPHOTRANSFERASE; PHOSPHOTRANSFERASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; DRUG ACTIVITY; DRUG SELECTIVITY; DRUG STRUCTURE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IC 50; NONHUMAN; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY;

EID: 53349162202     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.09.114     Document Type: Erratum

References (14)

1. Kane L.P., Lin J., and Weiss A. Curr. Opin. Immunol. 12 (2000) 242
2. Samelson L.E. Annu. Rev. Immunol. 20 (2002) 371
3. Ohashi P.S. Nat. Rev. Immunol. 2 (2002) 427
4. Lin T.A., McIntyre K.W., Das J., Liu C., O'Day K.D., Penhallow B., Hung C.Y., Whitney G.S., Shuster D.J., Yang X., Townsend R., Postelnek J., Spergel S.H., Lin J., Moquin R.V., Furch J.A., Kamath A.V., Zhang H., Marathe P.H., Perez-Villar J.J., Doweyko A., Killar L., Dodd J.H., Barrish J.C., Wityak J., and Kanner S.B. Biochemistry (2004) 11056
5. Liao X.C., and Littman D.R. Immunity (1995) 757
6. Schaeffer E.M., Debnath J., Yap G., McVicar D., Liao X.C., Littman D.R., Sher A., Varmus H.E., Lenardo M.J., and Schwartzberg P.L. Science 284 (1999) 638
7. Miller A.T., Wilcox H.M., Lai Z., and Berg L.J. Immunity 21 (2004) 67
8. Forssell J., Sideras P., Eriksson C., Malm-Erjefalt M., Rydell-Tormanen K., Ericsson P.O., and Erjefalt J.S. Am. J. Respir. Cell Mol. Biol. 32 (2005) 511
9. Das J., Liu C., Moquin R.V., Lin J., Furch J.A., Spergel S.H., Doweyko A.M., McIntyre K.W., Shuster D.J., O'Day K.D., Penhallow B., Hung C.Y., Kanner S.B., Lin T.A., Dodd J.H., Barrish J.C., and Wityak J. Bioorg. Med. Chem. Lett. 16 (2006) 4148
10. Kashem M.A., Nelson R.M., Yingling J.D., Pullen S.S., Prokopowicz III A.S., Jones J.W., Wolak J.P., Rogers G.R., Morelock M.M., Snow R.J., Homon C.A., and Jakes S. J. Biomol. Screen. 12 (2007) 70
11. Snow R.J., Abeywardane A., Campbell S., Lord J., Kashem M.A., Khine H.H., King J., Kowalski J.A., Pullen S.S., Roma T., Roth G.P., Sarko C.R., Wilson N.S., Winters M.P., Wolak J.P., and Cywin C.L. Bioorg. Med. Chem. Lett. 17 (2007) 3660
12. Nose A., and Kudo T. Chem. Pharm. Bull. 29 (1981) 1159
13. Bentzien, J. M.; Farmer, B., II; Pullen, S. S.; Studts, J. M.; White, A. WO 2005066335 A1 2005: 356 or X-ray crystallographic information.
14. White, A.; Abeywardane, A.; Cook, B. N.; Fuschetto, N.; Gautschi, E.; John, A.; Kroe, R. R.; Kronkaitis, A.; Li, Xiang; Pullen, S. S.; Roma, T.; Moriarty, K. J.; Roth, G. P.; Snow, R. J.; Studts, J. M.; Takahashi, H.; Farmer, B. T., II, J. Biol. Chem., submitted for publication.