Interleukin-2-inducible T cell kinase regulates mast cell degranulation and acute allergic responses

American Journal of Respiratory Cell and Molecular Biology

Volumn 32, Issue 6, 2005, Pages 511-520

  Forssell, Johan ^b   Sideras, Pascalis ^b   Eriksson, Christina ^b   Malm Erjefält, Monika ^b   Rydell Törmänen, Kristina ^b   Ericsson, Per Olof ^b   Erjefält, Jonas S ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b NONE

Author keywords

Allergy and immunology; Asthma; Signal transduction

Indexed keywords

ALLERGEN; BRUTON TYROSINE KINASE; COMPOUND 48-80; CYTOKINE; GUANINE NUCLEOTIDE BINDING PROTEIN; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G1; INTERLEUKIN 2 INDUCIBLE T LYMPHOCYTE KINASE; PEPTIDE; PROTEIN KINASE; UNCLASSIFIED DRUG;

ALLERGIC REACTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTHMA; CELL ACTIVATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; EOSINOPHILIA; IN VIVO STUDY; INFLAMMATION; LYMPHOCYTIC INFILTRATION; MAST CELL; MAST CELL DEGRANULATION; MOUSE; NONHUMAN; PROVOCATION TEST; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; TH2 CELL;

ACUTE DISEASE; ANIMALS; ASTHMA; CELL DEGRANULATION; HYPERSENSITIVITY; MAST CELLS; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; PROTEIN-TYROSINE KINASES; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 20044390229     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2004-0348OC     Document Type: Article

References (37)

1. Tattersfield AE, Knox AJ, Britton JR, Hall IP. Asthma. Lancet 2002; 360:1313-1322.
2. Herrick CA, Bottomly K. To respond or not to respond: T cells in allergic asthma. Nat Rev Immunol 2003;3:405-412.
3. Bochner BS, Lichtenstein LM. Anaphylaxis. N Engl J Med 1991;324: 1785-1790.
4. Kawakami T, Galli SJ. Regulation of mast-cell and basophil function and survival by IgE. Nat Rev Immunol 2002;2:773-786.
5. Hata D, Kawakami Y, Inagaki N, Lantz CS, Kitamura T, Khan WN, Maeda YM, Miura T, Han W, Hartman SE, et al. Involvement of Bruton's tyrosine kinase in FcepsilonRI-dependent mast cell degranulation and cytokine production. J Exp Med 1998;187:1235-1247.
6. Setoguchi R, Kinashi T, Sagara H, Hirosavva K, Takatsu K. Defective degranulation and calcium mobilization of bone marrow-derived mast cells from Xid and Btk-deficient mice. Immunol Lett 1998;64:109-118.
7. Kawakami Y, Kitaura J, Satterthwaite AB, Kato RM, Asai K, Hartman SE, Maeda-Yamamoto M, Lowell CA, Rawlings DJ, Witte ON, et al. Redundant and opposing functions of two tyrosine kinases, Btk and Lyn, in mast cell activation. J Immunol 2000;165:1210-1219.
8. Yamada N, Kawakami Y, Kimura H, Fukamachi H, Baier G, Altman A, Kato T, Inagaki Y, Kawakami T. Structure and expression of novel protein-tyrosine kinases, Emb and Emt, in hematopoietic cells. Biochem Biophys Res Commun 1993;192:231-240.
9. Kawakami Y, Yao L, Tashiro M, Gibson S, Mills GB, Kawakami T. Activation and interaction with protein kinase C of a cytoplasmic tyrosine kinase, Itk/Tsk/Emt, on Fc epsilon RI cross-linking on mast cells. J Immunol 1995;155:3556-3562.
10. Anderson GP, Coyle AJ. TH2 and 'TH2-like' cells in allergy and asthma: pharmacological perspectives. Trends Pharmacol Sci 1994;15:324-332. (see comments).
11. Foster PS, Mould AW, Yang M, MacKenzie J, Mattes J, Hogan SP, Mahalingam S, McKenzie AN, Rothenberg ME, Young IG, et al. Elemental signals regulating eosinophil accumulation in the lung. Immunol Rev 2001;179:173-181.
12. Wills-Karp M, Chiaramonte M. Interleukin-13 in asthma. Curr Opin Pulm Med 2003;9:21-27.
13. Schaeffer EM, Debnath J, Yap G, McVicar D, Liao XC, Littman DR, Sher A, Varmus HE, Lenardo MJ, Schwartzberg PL. Requirement for Tec kinases Rlk and Itk in T cell receptor signaling and immunity. Science 1999;284:638-641.
14. Fowell DJ, Shinkai K, Liao XC, Beebe AM, Coffman RL, Littman DR, Locksley RM. Impaired NFATc translocation and failure of Th2 development in Itk-deficient CD4+ T cells. Immunity 1999;11:399-409.
15. Mueller C, August A. Attenuation of immunological symptoms of allergic asthma in mice lacking the tyrosine kinase ITK. J Immunol 2003; 170:5056-5063.
16. Khan WN, Alt FW, Gerstein RM, Malynn BA, Larsson I, Rathbun G, Davidson L, Muller S, Kantor AB, Herzenberg LA, et al. Defective B cell development and function in Btk-deficient mice. Immunity 1995;3:283-299.
17. Liao XC, Littman DR. Altered T cell receptor signaling and disrupted T cell development in mice lacking Itk. Immunity 1995;3:757-769.
18. Korsgren M, Erjefält JS, Korsgren O, Sundler F, Persson CG. Allergic eosinophil-rich inflammation develops in lungs and airways of B cell-deficient mice. J Exp Med 1997;185:885-892.
19. Erjefält JS, Andersson P, Gustafsson B, Korsgren M, Sonmark B, Persson CGA. Allergen-challenge-induced extravasation of plasma in mouse airways. Clin Exp Allergy 1998;28:1013-1020.
20. McDonald DM. Endothelial gaps and permeability of venules in rat tracheas exposed to inflammatory stimuli. Am J Physiol 1994;266:L61-L83.
21. Dvorak AM, Tepper RI, Weller PF, Morgan ES, Estrella P, Monahan ER, Galli SJ. Piecemeal degranulation of mast cells in the inflammatory eyelid lesions of interleukin-4 transgenic mice: evidence of mast cell histamine release in vivo by diamine oxidase-gold enzyme-affinity ultrastructural cytochemistry. Blood 1994;83:3600-3612.
22. Oliani SM, Lim LH, Christian HC, Pell K, Das AM, Perretti M. Morphological alteration of peritoneal mast cells and macrophages in the mouse peritoneal cavity during the early phases of an allergic inflammatory reaction. Cell Biol Int 2001;25:795-803.
23. Finkelman FD, Snapper CM, Mountz JD, Katona IM. Polyclonal activation of the murine immune system by a goat antibody to mouse IgD. IX. Induction of a polyclonal IgE response. J Immunol 1987;138:2826-2830.
24. Shefler I, Sagi-Eisenberg R. Gi-mediated activation of the p42/p44 mitogen-activated protein kinases by receptor mimetic basic secretagogues is abrogated by inhibitors of endocytosis. Int Immunopharmacol 2002;2: 711-720.
25. Marone G, Galli SJ, Kitamura Y. Probing the roles of mast cells and basophils in natural and acquired immunity, physiology and disease. Trends Immunol 2002;23:425-427.
26. Sylvestre DL, Ravetch JV. A dominant role for mast cell Fc receptors in the Arthus reaction. Immunity 1996;5:387-390.
27. Mekori YA, Metcalfe DD. Mast cells in innate immunity. Immunol Rev 2000;173:131-140.
28. August A, Fischer A, Hao S, Mueller C, Ragin M. The Tec family of tyrosine kinases in T cells, amplifiers of T cell receptor signals. Int J Biochem Cell Biol 2002;34:1184-1189.
29. Langhans-Rajasekaran SA, Wan Y, Huang XY. Activation of Tsk and Btk tyrosine kinases by G protein beta gamma subunits. Proc Natl Acad Sci USA 1995;92:8601-8605.
30. August A, Sadra A, Dupont B, Hanafusa H. Src-induced activation of inducible T cell kinase (ITK) requires phosphatidylinositol 3-kinase activity and the Pleckstrin homology domain of inducible T cell kinase. Proc Natl Acad Sci USA 1997;94:11227-11232.
31. Scharenberg AM, El-Hillal O, Fruman DA, Beitz LO, Li Z, Lin S, Gout I, Cantley LC, Rawlings DJ, Kinet JP. Phosphatidylinositol-3,4, 5-trisphosphate (PtdIns-3,4,5-P3)/Tec kinase-dependent calcium signaling pathway: a target for SHIP-mediated inhibitory signals. EMBO J 1998;17:1961-1972.
32. Tsukada S, Simon MI, Witte ON, Katz A. Binding of beta gamma subunits of heterotrimeric G proteins to the PH domain of Bruton tyrosine kinase. Proc Natl Acad Sci USA 1994;91:11256-11260.
33. Bence K, Ma W, Kozasa T, Huang XY. Direct stimulation of Bruton's tyrosine kinase by G(q)-protein alpha-subunit. Nature 1997;389:296-299.
34. Lin TA, McIntyre KW, Das J, Liu C, O'Day KD, Penhallow B, Hung CY, Whitney GS, Shuster DJ, Yang X, et al. Selective itk inhibitors block T-cell activation and murine lung inflammation. Biochemistry 2004;43:11056-11062.
35. Schaeffer EM, Yap GS, Lewis CM, Czar MJ, McVicar DW, Cheever AW, Sher A, Schwartzberg PL. Mutation of Tec family kinases alters T helper cell differentiation. Nat Immunol 2001;12:1183-1188.
36. McLachlan JB, Hart JP, Pizzo SV, Shelburne CP, Staats HF, Gunn MD, Abraham SN. Mast cell-derived tumor necrosis factor induces hypertrophy of draining lymph nodes during infection. Nat Immunol 2003;4:1199-1205.
37. Maezawa Y, Nakajima H, Seto Y, Suto A, Kumano K, Kubo S, Karasuyama H, Saito Y, Iwamoto I. IgE-dependent enhancement of Th2 cell-mediated allergic inflammation in the airways. Clin Exp Immunol 2004;135:12-18.