메뉴 건너뛰기




Volumn 150, Issue 1, 2008, Pages 100-109

Short-Term Cyclosporine Therapy and Cotransplantation of Donor Splenocytes: Effects on Graft Rejection and Survival Rates in Pigs Subjected to Renal Transplantation

Author keywords

antigen presenting cells; cyclosporine A; dendritic cells; donor specific transfusion; kidney transplant

Indexed keywords

CYCLOSPORIN A;

EID: 53249121791     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2008.01.028     Document Type: Article
Times cited : (3)

References (56)
  • 1
    • 0000245578 scopus 로고
    • The fate of skin homografts in man
    • Gibson T., and Medawar P.B. The fate of skin homografts in man. J Anat 77 (1943) 299
    • (1943) J Anat , vol.77 , pp. 299
    • Gibson, T.1    Medawar, P.B.2
  • 2
    • 0005984244 scopus 로고
    • Actively acquired tolerance of foreign cells
    • Billingham R.E., Brent L., and Medawar P.B. Actively acquired tolerance of foreign cells. Nature 172 (1953) 603
    • (1953) Nature , vol.172 , pp. 603
    • Billingham, R.E.1    Brent, L.2    Medawar, P.B.3
  • 3
    • 4544246589 scopus 로고    scopus 로고
    • Prope tolerance-the future of organ transplantation from the laboratory to the clinic
    • Calne R.Y. Prope tolerance-the future of organ transplantation from the laboratory to the clinic. Transpl Immunol 13 (2004) 83
    • (2004) Transpl Immunol , vol.13 , pp. 83
    • Calne, R.Y.1
  • 4
    • 2342597756 scopus 로고    scopus 로고
    • Clinical transplantation tolerance: The promise and challenges
    • Ansari M.J.I., and Sayegh M.H. Clinical transplantation tolerance: The promise and challenges. Kidney Int 65 (2004) 1560
    • (2004) Kidney Int , vol.65 , pp. 1560
    • Ansari, M.J.I.1    Sayegh, M.H.2
  • 6
    • 33750296595 scopus 로고    scopus 로고
    • Costimulatory blockade induces hyporesponsiveness in T cells that recognize alloantigen via indirect antigen presentation
    • Phillips N.E., Greiner D.L., Mordes J.P., et al. Costimulatory blockade induces hyporesponsiveness in T cells that recognize alloantigen via indirect antigen presentation. Transplantation 82 (2006) 1085
    • (2006) Transplantation , vol.82 , pp. 1085
    • Phillips, N.E.1    Greiner, D.L.2    Mordes, J.P.3
  • 7
    • 8644235763 scopus 로고    scopus 로고
    • Induction of Fractalkine and CX3CR1 mediated by host CD8+ T cells in allograft tolerance induced by donor specific blood transfusion
    • Louvet C., Heslan J.M., Merieau E., et al. Induction of Fractalkine and CX3CR1 mediated by host CD8+ T cells in allograft tolerance induced by donor specific blood transfusion. Transplantation 78 (2004) 1259
    • (2004) Transplantation , vol.78 , pp. 1259
    • Louvet, C.1    Heslan, J.M.2    Merieau, E.3
  • 8
    • 33847713783 scopus 로고    scopus 로고
    • Functional compartmentalization following induction of long-term graft survival with pregraft donor-specific transfusion
    • Lair D., Degauque N., Miqueu P., et al. Functional compartmentalization following induction of long-term graft survival with pregraft donor-specific transfusion. Am J Transpl 7 (2007) 538
    • (2007) Am J Transpl , vol.7 , pp. 538
    • Lair, D.1    Degauque, N.2    Miqueu, P.3
  • 9
    • 4544374473 scopus 로고    scopus 로고
    • Tolerance induction in clinical transplantation
    • Fehr T., and Sykes M. Tolerance induction in clinical transplantation. Transpl Immunol 13 (2004) 117
    • (2004) Transpl Immunol , vol.13 , pp. 117
    • Fehr, T.1    Sykes, M.2
  • 10
    • 20344393915 scopus 로고    scopus 로고
    • Advances in strategies for inducing central tolerance in organ allograft recipients
    • Guenther D.A., and Madsen J.C. Advances in strategies for inducing central tolerance in organ allograft recipients. Pediatr Transpl 9 (2005) 277
    • (2005) Pediatr Transpl , vol.9 , pp. 277
    • Guenther, D.A.1    Madsen, J.C.2
  • 11
    • 0344553377 scopus 로고    scopus 로고
    • Heterologous immunity: An over-looked barrier to tolerance
    • Adams A.B., Pearson T.C., and Larsen C.P. Heterologous immunity: An over-looked barrier to tolerance. Immunol Rev 196 (2003) 147
    • (2003) Immunol Rev , vol.196 , pp. 147
    • Adams, A.B.1    Pearson, T.C.2    Larsen, C.P.3
  • 12
    • 85047693403 scopus 로고    scopus 로고
    • Tolerance of mice and men
    • Sachs D.H. Tolerance of mice and men. J Clin Invest 111 (2003) 1819
    • (2003) J Clin Invest , vol.111 , pp. 1819
    • Sachs, D.H.1
  • 13
    • 33444473953 scopus 로고    scopus 로고
    • Influence of immunosuppressive drugs on cell-induced graft tolerance
    • Heitger A., Blaha P., Bigenzahn S., et al. Influence of immunosuppressive drugs on cell-induced graft tolerance. Curr Opin Organ Transpl 9 (2004) 307
    • (2004) Curr Opin Organ Transpl , vol.9 , pp. 307
    • Heitger, A.1    Blaha, P.2    Bigenzahn, S.3
  • 14
    • 0038576227 scopus 로고    scopus 로고
    • The influence of immunosuppressive drugs on tolerance induction through bone marrow transplantation with costimulation blockade
    • Blaha P., Bigenzahn S., Koporc Z., et al. The influence of immunosuppressive drugs on tolerance induction through bone marrow transplantation with costimulation blockade. Blood 101 (2003) 2886
    • (2003) Blood , vol.101 , pp. 2886
    • Blaha, P.1    Bigenzahn, S.2    Koporc, Z.3
  • 15
    • 53249139854 scopus 로고    scopus 로고
    • Calcineurin inhibitor: Influence of dose and timing on regulatory cells and graft acceptance
    • Sept
    • Takahashi K., Kawai M., Waer M., et al. Calcineurin inhibitor: Influence of dose and timing on regulatory cells and graft acceptance. Transpl Int 20 (2007) 152 Sept
    • (2007) Transpl Int , vol.20 , pp. 152
    • Takahashi, K.1    Kawai, M.2    Waer, M.3
  • 16
    • 31044442028 scopus 로고    scopus 로고
    • Transplant tolerance: Converging on a moving target
    • Newell K.A., Larsen C.P., and Kirk A.D. Transplant tolerance: Converging on a moving target. Transplantation 81 (2006) 1
    • (2006) Transplantation , vol.81 , pp. 1
    • Newell, K.A.1    Larsen, C.P.2    Kirk, A.D.3
  • 17
    • 0038771218 scopus 로고    scopus 로고
    • The mosaic of immunosuppressive drugs
    • Masri M.A. The mosaic of immunosuppressive drugs. Mol Immunol 39 (2003) 1073
    • (2003) Mol Immunol , vol.39 , pp. 1073
    • Masri, M.A.1
  • 18
    • 0035987403 scopus 로고    scopus 로고
    • New developments in immunosuppressive therapy in renal transplantation
    • Gourishankar S., Turner P., and Halloran P. New developments in immunosuppressive therapy in renal transplantation. Exp Opin Biol Ther 2 (2002) 483
    • (2002) Exp Opin Biol Ther , vol.2 , pp. 483
    • Gourishankar, S.1    Turner, P.2    Halloran, P.3
  • 19
    • 4544248633 scopus 로고    scopus 로고
    • The road to tolerance: Renal transplant tolerance induction in nonhuman primate studies and clinical trials
    • Elster E.A., Hale D.A., Mannon R.B., et al. The road to tolerance: Renal transplant tolerance induction in nonhuman primate studies and clinical trials. Transpl Immunol 13 (2004) 87
    • (2004) Transpl Immunol , vol.13 , pp. 87
    • Elster, E.A.1    Hale, D.A.2    Mannon, R.B.3
  • 20
    • 0033608835 scopus 로고    scopus 로고
    • Immunosuppressive strategies in transplantation
    • Denton M.D., Magee C.C., and Sayegh M.H. Immunosuppressive strategies in transplantation. Lancet 353 (1999) 1083
    • (1999) Lancet , vol.353 , pp. 1083
    • Denton, M.D.1    Magee, C.C.2    Sayegh, M.H.3
  • 21
    • 20544438039 scopus 로고    scopus 로고
    • Induction of transplantation tolerance-the potential of regulatory T cells
    • Akl A., Luo S., and Wood K.J. Induction of transplantation tolerance-the potential of regulatory T cells. Transpl Immunol 14 (2005) 225
    • (2005) Transpl Immunol , vol.14 , pp. 225
    • Akl, A.1    Luo, S.2    Wood, K.J.3
  • 22
    • 0034885989 scopus 로고    scopus 로고
    • Potential of tolerogenic dendritic cells for transplantation
    • Morelli A.E., Hackstein H., and Thomson A.W. Potential of tolerogenic dendritic cells for transplantation. Semin Immunol 13 (2001) 323
    • (2001) Semin Immunol , vol.13 , pp. 323
    • Morelli, A.E.1    Hackstein, H.2    Thomson, A.W.3
  • 23
    • 0030586611 scopus 로고    scopus 로고
    • Dendritic cells can present antigen in vivo in a tolerogenic or immunogenic fashion
    • Finkelman F.D., Lees A., Birnbaum R., et al. Dendritic cells can present antigen in vivo in a tolerogenic or immunogenic fashion. J Immunol 157 (1996) 1406
    • (1996) J Immunol , vol.157 , pp. 1406
    • Finkelman, F.D.1    Lees, A.2    Birnbaum, R.3
  • 24
    • 1842472899 scopus 로고    scopus 로고
    • Mixed chimerism and transplantation tolerance
    • Cosimi A.B., and Sachs D.H. Mixed chimerism and transplantation tolerance. Transplantation 77 (2004) 943
    • (2004) Transplantation , vol.77 , pp. 943
    • Cosimi, A.B.1    Sachs, D.H.2
  • 25
    • 1642329323 scopus 로고    scopus 로고
    • Donor antigen and transplant tolerance strategies: It takes two to tango!
    • Womer K.L., and Sayegh M.H. Donor antigen and transplant tolerance strategies: It takes two to tango!. J Am Soc Nephrol 15 (2004) 1101
    • (2004) J Am Soc Nephrol , vol.15 , pp. 1101
    • Womer, K.L.1    Sayegh, M.H.2
  • 26
    • 30144434468 scopus 로고    scopus 로고
    • Immunologic unresponsiveness in chimeric miniature swine following MHC-mismatched spleen transplantation
    • Dor F.J., Tseng Y.L., Kuwaki K., et al. Immunologic unresponsiveness in chimeric miniature swine following MHC-mismatched spleen transplantation. Transplantation 80 (2005) 1791
    • (2005) Transplantation , vol.80 , pp. 1791
    • Dor, F.J.1    Tseng, Y.L.2    Kuwaki, K.3
  • 27
    • 32844459645 scopus 로고    scopus 로고
    • Immunosuppressive and trafficking properties of donor splenic and bone marrow dendritic cells
    • Emmanouilidis N., Guo Z., Dong Y., et al. Immunosuppressive and trafficking properties of donor splenic and bone marrow dendritic cells. Transplantation 81 (2006) 455
    • (2006) Transplantation , vol.81 , pp. 455
    • Emmanouilidis, N.1    Guo, Z.2    Dong, Y.3
  • 28
    • 0343488437 scopus 로고    scopus 로고
    • Induction of transplantation tolerance in adult rats by vascularized spleen transplantation
    • Suzuki H., Li X.H., Miyamoto M., et al. Induction of transplantation tolerance in adult rats by vascularized spleen transplantation. Transplantation 64 (1997) 650
    • (1997) Transplantation , vol.64 , pp. 650
    • Suzuki, H.1    Li, X.H.2    Miyamoto, M.3
  • 29
    • 0030860995 scopus 로고    scopus 로고
    • Prolonged survival of mouse skin allografts in recipients treated with donor splenocytes and antibody to CD40 ligand
    • Markees T.G., Phillips N.E., Noelle R.J., et al. Prolonged survival of mouse skin allografts in recipients treated with donor splenocytes and antibody to CD40 ligand. Transplantation 64 (1997) 329
    • (1997) Transplantation , vol.64 , pp. 329
    • Markees, T.G.1    Phillips, N.E.2    Noelle, R.J.3
  • 30
    • 0041525812 scopus 로고    scopus 로고
    • Can spleen transplantation induce tolerance?. A review of the literature
    • Dor F.J.M.F., Gollackner B., and Cooper D.K.C. Can spleen transplantation induce tolerance?. A review of the literature. Transpl Int 16 (2003) 451
    • (2003) Transpl Int , vol.16 , pp. 451
    • Dor, F.J.M.F.1    Gollackner, B.2    Cooper, D.K.C.3
  • 31
    • 10744230215 scopus 로고    scopus 로고
    • Spleen transplantation in miniature swine: Surgical technique and results in major histocompatibility complex-matched donor and recipient pairs
    • Gollackner B., Dor F.J.M.F., Knosalla C., et al. Spleen transplantation in miniature swine: Surgical technique and results in major histocompatibility complex-matched donor and recipient pairs. Transplantation 75 (2003) 1799
    • (2003) Transplantation , vol.75 , pp. 1799
    • Gollackner, B.1    Dor, F.J.M.F.2    Knosalla, C.3
  • 32
    • 0023900513 scopus 로고
    • Marked interspecies differences between humans and pigs in cyclosporine and prednisolone disposition
    • Frey B.M., Sieber M., Mettler D., et al. Marked interspecies differences between humans and pigs in cyclosporine and prednisolone disposition. Drug Metab Dispos 16 (1988) 285
    • (1988) Drug Metab Dispos , vol.16 , pp. 285
    • Frey, B.M.1    Sieber, M.2    Mettler, D.3
  • 33
    • 23844475065 scopus 로고    scopus 로고
    • Tacrolimus versus cyclosporine induction therapy in pulmonary transplantation in miniature swine
    • Warnecke G., Avsar M., Steinkamp T., et al. Tacrolimus versus cyclosporine induction therapy in pulmonary transplantation in miniature swine. Eur J Cardiothorac Surg 28 (2005) 454
    • (2005) Eur J Cardiothorac Surg , vol.28 , pp. 454
    • Warnecke, G.1    Avsar, M.2    Steinkamp, T.3
  • 34
    • 0023903095 scopus 로고
    • Investigation of the mechanism of active enhancement of renal allograft survival by blood transfusion
    • Quigley R.L., Wood K.J., and Morris P.J. Investigation of the mechanism of active enhancement of renal allograft survival by blood transfusion. Immunology 63 (1988) 373
    • (1988) Immunology , vol.63 , pp. 373
    • Quigley, R.L.1    Wood, K.J.2    Morris, P.J.3
  • 35
    • 0029626656 scopus 로고
    • Donor-specific transfusions have long-term beneficial effects for human renal allografts
    • Flye M.W., Burton K., Mohanakumar T., et al. Donor-specific transfusions have long-term beneficial effects for human renal allografts. Transplantation 60 (1995) 1395
    • (1995) Transplantation , vol.60 , pp. 1395
    • Flye, M.W.1    Burton, K.2    Mohanakumar, T.3
  • 36
    • 0036703995 scopus 로고    scopus 로고
    • Long-term graft survival with or without donor-specific transfusion in cyclosporine era in one haplo-identical living-related renal transplant recipients beyond the first year: A 19-year experience
    • Satoh S., Sugimura J., Omori S., et al. Long-term graft survival with or without donor-specific transfusion in cyclosporine era in one haplo-identical living-related renal transplant recipients beyond the first year: A 19-year experience. Tohoku J Exp Med 197 (2002) 201
    • (2002) Tohoku J Exp Med , vol.197 , pp. 201
    • Satoh, S.1    Sugimura, J.2    Omori, S.3
  • 37
    • 0035025762 scopus 로고    scopus 로고
    • Mixed chimerism and transplantation tolerance
    • Sykes M. Mixed chimerism and transplantation tolerance. Immunity 14 (2001) 417
    • (2001) Immunity , vol.14 , pp. 417
    • Sykes, M.1
  • 38
    • 0029664599 scopus 로고    scopus 로고
    • Prevention of Th1 response is critical for tolerance
    • Chen N., Gao Q., and Field E.H. Prevention of Th1 response is critical for tolerance. Transplantation 61 (1996) 1076
    • (1996) Transplantation , vol.61 , pp. 1076
    • Chen, N.1    Gao, Q.2    Field, E.H.3
  • 39
    • 0041966982 scopus 로고    scopus 로고
    • Pretransplant blood transfusion without additional immunotherapy generates CD25+CD4+ regulatory T cells: A potential explanation for the blood-transfusion effect
    • Bushell A., Karim M., Kingsley C.I., et al. Pretransplant blood transfusion without additional immunotherapy generates CD25+CD4+ regulatory T cells: A potential explanation for the blood-transfusion effect. Transplantation 76 (2003) 449
    • (2003) Transplantation , vol.76 , pp. 449
    • Bushell, A.1    Karim, M.2    Kingsley, C.I.3
  • 40
    • 0034794768 scopus 로고    scopus 로고
    • Challenges to achieving clinical transplantation tolerance
    • Salama A.D., Remuzzi G., Harmon W.E., et al. Challenges to achieving clinical transplantation tolerance. J Clin Invest 108 (2001) 943
    • (2001) J Clin Invest , vol.108 , pp. 943
    • Salama, A.D.1    Remuzzi, G.2    Harmon, W.E.3
  • 41
    • 0042466713 scopus 로고    scopus 로고
    • Regulatory cell-mediated tolerance does not protect against chronic rejection
    • Koshiba T., Kitade H., Van Damme B., et al. Regulatory cell-mediated tolerance does not protect against chronic rejection. Transplantation 76 (2003) 588
    • (2003) Transplantation , vol.76 , pp. 588
    • Koshiba, T.1    Kitade, H.2    Van Damme, B.3
  • 42
    • 0344984407 scopus 로고    scopus 로고
    • Dendritic cells: Regulators of alloimmunity and opportunities for tolerance induction
    • Morelli A.E., and Thomson A.W. Dendritic cells: Regulators of alloimmunity and opportunities for tolerance induction. Immunol Rev 196 (2003) 125
    • (2003) Immunol Rev , vol.196 , pp. 125
    • Morelli, A.E.1    Thomson, A.W.2
  • 43
    • 33644622771 scopus 로고    scopus 로고
    • Manipulation of dendritic cells in organ transplantation: A major step towards graft tolerance?
    • Abe M., Hackstein H., and Thomson A.W. Manipulation of dendritic cells in organ transplantation: A major step towards graft tolerance?. Curr Opin Organ Transpl 9 (2004) 294
    • (2004) Curr Opin Organ Transpl , vol.9 , pp. 294
    • Abe, M.1    Hackstein, H.2    Thomson, A.W.3
  • 44
    • 0033920970 scopus 로고    scopus 로고
    • The effect of calcineurin inhibitors and corticosteroids on the differentiation of human dendritic cells
    • Woltman A.M., de Fijter J.W., Kamerling S.W., et al. The effect of calcineurin inhibitors and corticosteroids on the differentiation of human dendritic cells. Eur J Immunol 30 (2000) 1807
    • (2000) Eur J Immunol , vol.30 , pp. 1807
    • Woltman, A.M.1    de Fijter, J.W.2    Kamerling, S.W.3
  • 45
    • 0033571233 scopus 로고    scopus 로고
    • Cyclosporine A inhibits the expression of costimulatory molecules on in vitro-generated dendritic cells: Association with reduced nuclear translocation of nuclear factor κB
    • Lee J.I., Ganster R.W., Geller D.A., et al. Cyclosporine A inhibits the expression of costimulatory molecules on in vitro-generated dendritic cells: Association with reduced nuclear translocation of nuclear factor κB. Transplantation 68 (1999) 1255
    • (1999) Transplantation , vol.68 , pp. 1255
    • Lee, J.I.1    Ganster, R.W.2    Geller, D.A.3
  • 46
    • 0037120053 scopus 로고    scopus 로고
    • Interleukine-2 signaling is required for CD4(+) regulatory T cell function
    • Furtado G.C., Curotto de Lafaille M.A., et al. Interleukine-2 signaling is required for CD4(+) regulatory T cell function. J Exp Med 196 (2002) 851
    • (2002) J Exp Med , vol.196 , pp. 851
    • Furtado, G.C.1    Curotto de Lafaille, M.A.2
  • 48
    • 0034763579 scopus 로고    scopus 로고
    • Experimental study of combined treatment with tacrolimus and donor splenocytes via the portal vein in small bowel transplantation
    • Miyauchi T., Ishikawa M., Tashiro S., et al. Experimental study of combined treatment with tacrolimus and donor splenocytes via the portal vein in small bowel transplantation. J Med Invest 48 (2001) 157
    • (2001) J Med Invest , vol.48 , pp. 157
    • Miyauchi, T.1    Ishikawa, M.2    Tashiro, S.3
  • 49
    • 0036363768 scopus 로고    scopus 로고
    • Prolongation of rat kidney graft survival after inoculation of allogeneic spleen cells: The effect of various routes of cell transfer
    • Oko A., Idasiak-Piechocka I., Pawlaczyk K., et al. Prolongation of rat kidney graft survival after inoculation of allogeneic spleen cells: The effect of various routes of cell transfer. Ann Transpl 7 (2002) 51
    • (2002) Ann Transpl , vol.7 , pp. 51
    • Oko, A.1    Idasiak-Piechocka, I.2    Pawlaczyk, K.3
  • 50
    • 0030801042 scopus 로고    scopus 로고
    • A strategy for generating consistent long-term donor-specific tolerance to solid organ allografts
    • Levy A.E., Alexander J.W., and Babcock G.F. A strategy for generating consistent long-term donor-specific tolerance to solid organ allografts. Transpl Immunol 5 (1997) 83
    • (1997) Transpl Immunol , vol.5 , pp. 83
    • Levy, A.E.1    Alexander, J.W.2    Babcock, G.F.3
  • 51
    • 0034041267 scopus 로고    scopus 로고
    • Mechanism of tolerance induction and prevention of cardiac allograft vasculopathy in miniature swine: The effect of augmentation of donor antigen load
    • Yamada K., Mawulawde K., Menard M.T., et al. Mechanism of tolerance induction and prevention of cardiac allograft vasculopathy in miniature swine: The effect of augmentation of donor antigen load. J Thorac Cardiovasc Surg 119 (2000) 709
    • (2000) J Thorac Cardiovasc Surg , vol.119 , pp. 709
    • Yamada, K.1    Mawulawde, K.2    Menard, M.T.3
  • 52
    • 0033759289 scopus 로고    scopus 로고
    • Prolongation of heterotopic heart allograft survival by portal venous injection of alloantigen: The role of hepatic nonparenchymal cells
    • Smith R.M., Chen Y., McKenna G.J., et al. Prolongation of heterotopic heart allograft survival by portal venous injection of alloantigen: The role of hepatic nonparenchymal cells. J Clin Surg 13 (2000) 241
    • (2000) J Clin Surg , vol.13 , pp. 241
    • Smith, R.M.1    Chen, Y.2    McKenna, G.J.3
  • 53
    • 2142760087 scopus 로고    scopus 로고
    • Effective induction of immune tolerance by portal venous infusion with IL-10 gene-modified immature dendritic cells leading to prolongation of allograft survival
    • Zhang M., Wang Q., Liu Y., et al. Effective induction of immune tolerance by portal venous infusion with IL-10 gene-modified immature dendritic cells leading to prolongation of allograft survival. J Mol Med 82 (2004) 240
    • (2004) J Mol Med , vol.82 , pp. 240
    • Zhang, M.1    Wang, Q.2    Liu, Y.3
  • 54
    • 0034533209 scopus 로고    scopus 로고
    • Efficient presentation of exogenous antigen by liver endothelial cells to CD8+ T cells results in antigen-specific T cell tolerance
    • Limmer A., Ohl J., Kurts C., et al. Efficient presentation of exogenous antigen by liver endothelial cells to CD8+ T cells results in antigen-specific T cell tolerance. Nat Med 6 (2000) 1348
    • (2000) Nat Med , vol.6 , pp. 1348
    • Limmer, A.1    Ohl, J.2    Kurts, C.3
  • 55
    • 0037686692 scopus 로고    scopus 로고
    • Hepatic allograft-derived Kupffer cells regulate T cell response in rats
    • Sun Z., Wada T., Maemura K., et al. Hepatic allograft-derived Kupffer cells regulate T cell response in rats. Liver Transpl 9 (2003) 489
    • (2003) Liver Transpl , vol.9 , pp. 489
    • Sun, Z.1    Wada, T.2    Maemura, K.3
  • 56
    • 0028143235 scopus 로고
    • Mechanism of cyclosporin-induced tolerance to primarily vascularized allograft in miniature swine
    • Gianello P.R., Blancho G., Fishbein J.F., et al. Mechanism of cyclosporin-induced tolerance to primarily vascularized allograft in miniature swine. J Immunol 153 (1994) 4788
    • (1994) J Immunol , vol.153 , pp. 4788
    • Gianello, P.R.1    Blancho, G.2    Fishbein, J.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.