Synthesis and properties of 3′-amino-2′,4′-BNA, a bridged nucleic acid with a N3′→P5′ phosphoramidate linkage

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 20, 2008, Pages 9230-9237

  Obika, Satoshi ^a   Rahman, S M Abdur ^a   Song, Bingbing ^a   Onoda, Mayumi ^a   Koizumi, Makoto ^b   Morita, Koji ^b   Imanishi, Takeshi ^a  

^a OSAKA UNIVERSITY   (Japan)

^b DAIICHI SANKYO CO   (Japan)

Author keywords

Bridged nucleic acids; Locked nucleic acids; Oligonucleotide N3 P5 phosphoramidates

Indexed keywords

BRIDGED COMPOUND; BRIDGED NUCLEIC ACID; DOUBLE STRANDED DNA; PHOSPHORAMIDIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DNA STRUCTURE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NUCLEOTIDE SEQUENCE; REACTION ANALYSIS; SYNTHESIS;

AMIDES; AMINES; BRIDGED COMPOUNDS; DIMERIZATION; MOLECULAR STRUCTURE; NUCLEIC ACID DENATURATION; NUCLEIC ACIDS; NUCLEOTIDES; PHOSPHORIC ACIDS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TEMPERATURE;

EID: 53249113120     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.09.013     Document Type: Article

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