Synthesis and properties of hammerhead ribozymes stabilized against nucleases by different 2'-modifications: Methoxyethoxy-, fluoro- and amino groups

Bioorganic and Medicinal Chemistry Letters

Volumn 7, Issue 13, 1997, Pages 1791-1796

  Scherr, Michaela ^a   Klebba, Christian ^a   Häner, Robert ^b   Ganser, Arnold ^c   Engels, Joachim W ^a  

^a GOETHE UNIVERSITY   (Germany)

^b NOVARTIS PHARMA AG   (Switzerland)

^c HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEASE; RIBONUCLEOSIDE; RIBOZYME;

ARTICLE; CANCER CONTROL; ENZYME CONFORMATION; ENZYME MODIFICATION; ENZYME STABILITY; ENZYME SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LIPOPHILICITY;

EID: 0030763140     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(97)00313-2     Document Type: Article

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