Efficacy of orally administered Lobelia chinensis extracts on herpes simplex virus type 1 infection in BALB/c mice

Antiviral Research

Volumn 80, Issue 2, 2008, Pages 206-212

  Kuo, Yuh Chi ^a   Lee, Yuh Chi ^a   Leu, Yann Lii ^b   Tsai, Wei Jern ^c,d   Chang, Shi Chuan ^e,f  

^a FU JEN CATHOLIC UNIVERSITY   (Taiwan)

^b CHANG GUNG UNIVERSITY   (Taiwan)

^c NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

^d National Tai Tung University   (Taiwan)

^e NATIONAL YANG MING UNIVERSITY   (Taiwan)

^f TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

DNA levels; HSV 1; In vitro; In vivo; L. chinensis; Zoster lesions

Indexed keywords

ACICLOVIR; LOBELIA CHINENSIS EXTRACT; PLANT EXTRACT; UNCLASSIFIED DRUG; VIRUS DNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIVIRAL ACTIVITY; ARTICLE; BAGG ALBINO MOUSE; CELL VIABILITY; CONTROLLED STUDY; DOSE KIDNEY FUNCTION RELATION; DOSE LIVER FUNCTION RELATION; DRUG DOSE COMPARISON; DRUG SAFETY; HELA CELL; HERPES SIMPLEX; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; LOBELIA; LOBELIA CHINENSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; VIRUS INHIBITION; VIRUS LOAD;

ACYCLOVIR; ANIMALS; ANTIVIRAL AGENTS; CELL SURVIVAL; DRUG ADMINISTRATION SCHEDULE; HELA CELLS; HERPES SIMPLEX; HERPESVIRUS 1, HUMAN; HUMANS; KIDNEY; LIVER; LOBELIA; MICE; MICE, INBRED BALB C; PLANT EXTRACTS; SKIN; VIRUS REPLICATION;

ANIMALIA; HUMAN HERPESVIRUS 1; LOBELIA CHINENSIS; MUS;

EID: 53249086085     PISSN: 01663542     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.antiviral.2008.06.009     Document Type: Article

References (33)

1. Alrabiah F.A., and Sacks S.L. New antiherpes virus agents: their targets and therapeutic potential. Drugs 52 (1996) 17-32
2. Arisawa M., Fujita A., Hayashi T., Hayashi K., Ochiai H., and Morita N. Cytotoxic and antiherpetic activity of phloroglucinol derivatives from Mallotus japonicus (Euphorbiaceae). Chem. Pharm. Bull. 38 (1990) 1624-1626
3. Betz U.A.K., Fischer R., Kleymann G., Hendrix M., and Rübsamen-Waigmann H. Potent in vivo antiviral activity of the herpes simplex virus primase-helicase inhibitor BAY 57-1293. Antimicrob. Agents Ch. 46 (2002) 1766-1772
4. Chen H., Teng L., Li J.N., Park R., Mold D.E., Gnabre J., Hwu J.R., Tseng W.N., and Huang R.C. Antiviral activities of methylated nordihydroguaiaretic acids. 2. Targeting herpes simplex virus replication by the mutation insensitive transcription inhibitor tetra-O-methyl-NDGA. J. Med. Chem. 41 (1998) 3001-3007
5. Chen Y.C., Tsai W.J., Wu M.H., Lin L.C., and Kuo Y.C. Suberosin inhibits human peripheral blood mononuclear cells proliferation through the modulation of NF-AT and NF-κB transcription factors. Brit. J. Pharmacol. 150 (2007) 298-312
6. Chibo D., Druce J., Sasadeusz J., and Birch C. Molecular analysis of clinical isolates of acyclovir resistant herpes simplex virus. Antivir. Res. 61 (2004) 83-91
7. Coen D.M. Antiviral drug resistance in herpes simplex virus. Adv. Exp. Med. Biol. 394 (1996) 49-57
8. Cone R.W., Hobson A.C., Palmer J., Remington M., and Corey L. Extended duration of herpes simplex virus DNA in genital lesions detected by the polymerase chain reaction. J. Infect. Dis. 164 (1991) 757-760
9. Corey L., Wald A., Celum C.L., and Quinn T.C. The effects of herpes simplex virus-2 on HIV-1 acquisition and transmission: a review of two overlapping epidemics. J. Acquir. Immune. Defic. Syndr. 35 (2004) 435-445
10. Darby G. A history of antiherpes research. Antivir. Chem. Chemother. 5 Suppl. 1 (1994) 3-9
11. Elbein A.D. Inhibitors of the biosynthesis and processing of N-linked oligosaccharide chains. Annu. Rev. Biochem. 56 (1987) 497-534
12. Flammia D., Dukat M., Imad Damaj M., Martin B., and Glennon R.A. Lobeline: structure-affinity investigation of nicotinic acetylcholinergic receptor binding. J. Med. Chem. 42 (1999) 3726-3731
13. Imai Y., Shum C., Martin D.F., Kuppermann B.D., Drew W.L., and Margolis T.P. Emergence of drug-resistant cytomegalovirus retinitis in the contralateral eyes of patients with AIDS treated with ganciclovir. J. Infect. Dis. 189 (2004) 611-615
14. Kimberlin D.W., and Whitley R.J. Antiviral resistance: mechanisms, clinical significance, and future implications. J. Antimicrob. Chemoth. 37 (1996) 403-421
15. Kuo Y.C., Lin Y.L., Huang C.P., Shu J.W., and Tsai W.J. A tumor cell growth inhibitor from Saposhnikovae divaricata. Cancer Invest. 20 (2002) 7-11
16. Kuo Y.C., Lin L.C., Tsai W.J., Chou C.J., Kung S.H., and Ho Y.H. Samaragenin B identified from Limonium sinense suppressed herpes simplex virus type 1 replication in Vero cells by regulation of viral macromolecular synthesis. Antimicrob. Agents Ch. 46 (2002) 2854-2864
17. Kuo Y.C., Kuo Y.S., Lin Y.L., and Tsai W.J. Yatein from Chamaecyparis obtusa suppresses herpes simplex virus type 1 replication in HeLa cells by interruption the immediate-early gene expression. Antiviral. Res. 70 (2006) 112-120
18. Kuo Y.C., Chen C.C., Tsai W.J., and Ho Y.H. Regulation of herpes simplex virus type 1 replication in Vero cells by Psychotria serpens: relationship to gene expression, DNA replication, and protein synthesis. Antivir. Res. 51 (2001) 95-109
19. Kurokawa M., Ochiai H., Nagasaka K., Neki M., Xu H., Kadota S., Sutardjo S., Matsumoto T., Namba T., and Shiraki K. Antiviral traditional medicines against herpes simplex virus (HSV-1), poliovirus, and measles virus in vitro and their therapeutic efficacies for HSV-1 infection in mice. Antivir. Res. 22 (1993) 175-188
20. Mann S.L., Meyers J.D., Holmes K.L., and Corey L. Prevalence and incidence of herpesvirus infections among homosexually active men. J. Infect. Dis. 149 (1984) 1026-1027
21. Marchetti M., Pisani S., Pietropaola V., Seganti L., Nicoletti R., Degener A., and Orsi N. Antiviral effect of a polysaccharide from Sclerotium glucanicum towards herpes simplex virus type 1 infection. Planta Med. 62 (1996) 303-307
22. Miller D.K., Lever J.R., Rodvelt K.R., Baskett J.A., Will M.J., and Kracke G.R. Lobeline, a potential pharmacotherapy for drug addiction, binds to m opioid receptors and diminishes the effects of opioid receptor agonists. Drug Alcohol Depen. 89 (2007) 282-291
23. Pope L.E., Marceletti J.F., Katz L.R., and Katz D.H. Anti-herpes simplex virus activity of n-docosanol correlates with intracellular metabolic conversion of the drug. J. Lipid Res. 37 (1996) 2167-2178
24. Roizman B., and Sears A.E. Herpes Simplex Virus and Their Replication. In: Fields B.N., Knipe D.M., and Howley P.M. (Eds). Fundamental Virology. 3rd ed. (1996), Lippincott-Raven Publishers, Philadelphia 2231-2295
25. Sacks S.L., Thisted R.A., Jones T.M., Barbarash R.A., Mikolich D.J., Ruoff G.E., Jorizzo J.L., Gunnill L.B., Katz D.H., Khalil M.H., Morrow P.R.G., Yakatan J., Pope L.E., and Berge J.E. The Docosanol 10% cream study group. Clinical efficacy of topical docosanol 10% cream for herpes simplex labialis: a multicenter, randomized, placebo-controlled trial. J. Am. Acad. Dermatol. 45 (2001) 222-230
26. Santosa M.H., Herzog R., and Voelter W. Antitumor activity on the hot water extract of Lobelia chinensis. Planta Med. 52 (1986) 555-558
27. Shibano M., Tsukamoto D., Masuda A., Tanaka Y., and Kusano G. Two new pyrrolidine alkaloids, radicamines A and B, as inhibitors of α-glucosidase from Lobelia chinensis Lour. Chem. Pharm. Bull. 49 (2001) 1362-1365
28. Shibano M., Kitagawa S., Nakamura S., Akazawa N., and Kusano G. Studies on the constituents of Broussonetia species. II. Six new pyrrolidine alkaloids, broussonetine A, B, E, F and broussonetinine A and B, as inhibitors of glycosidases from Broussonetia kazinoki Sieb. Chem. Pharm. Bull. 45 (1997) 700-705
29. Simõnes C.M.O., Amoros M., and Girre L. Mechanism of antiviral activity of triterpenoid saponins. Phytother. Res. 21 (1999) 317-325
30. Stranska R., van Loon A.M., Bredius R.G., Polman M., Nienhuis E., Beersma M.F., Lankester A.C., and Schuurman R. Sequential switching of DNA polymerase and thymidine kinase-mediated HSV-1 drug resistance in an immunocompromised child. Antivir. Ther. 9 (2004) 97-104
31. Sydiskis R.J., Owen D.G., Lohr J.L., Rosler K.H., and Blomster R.N. Inactivation of enveloped viruses by anthraquinones extracted from plants. Antimicrob. Agents Chemother. 35 (1991) 2463-2466
32. Tian Q., Zhao D., Zhang J., Gao L., Liu S., Yang J., Su J., Zhang Z., Tang J., and Tang C. Investigation on inhibition of biological effects of endothelin. Sci. China C. Life Sci. 39 (1996) 207-216
33. Waggoner-Fountain L.A., and Grossman L.B. Herpes simplex virus. Pediatr. Rev. 25 (2004) 86-93