Polymorphisms affecting gene transcription and mRNA processing in pharmacogenetic candidate genes: Detection through allelic expression imbalance in human target tissues

Pharmacogenetics and Genomics

Volumn 18, Issue 9, 2008, Pages 781-791

  Johnson, Andrew D ^a   Zhang, Ying ^a   Papp, Audrey C ^a   Pinsonneault, Julia K ^a   Lim, Jeong Eun ^a   Saffen, David ^a   Dai, Zunyan ^a   Wang, Danxin ^a   Sadée, Wolfgang ^a  

^a THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

ACE; Allele expression imbalance; Allelic expression; Angiotensin; Gene expression; Mitochondrial manganese superoxide dismutase; Pharmacogenetic; Pharmacogenomic; Polymorphism; RNA structure; Single nucleotide polymorphism

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE; MANGANESE SUPEROXIDE DISMUTASE; MESSENGER RNA;

ALLELE; ALLELIC EXPRESSION IMBALANCE; ARTICLE; BRAIN; DRD2 GENE; GENE; GENE CONTROL; GENETIC POLYMORPHISM; GENETIC TRANSCRIPTION; HEART; HUMAN; HUMAN TISSUE; INTESTINE; LIVER; LYMPHOCYTE; MDR1 GENE; NUCLEOTIDE SEQUENCE; OPRM1 GENE; PHARMACOGENETICS; PHENOTYPIC VARIATION; PRIORITY JOURNAL; PROMOTER REGION; REGULATORY MECHANISM; REPORTER GENE; RNA PROCESSING; SINGLE NUCLEOTIDE POLYMORPHISM; TPH2 GENE; VKORC1 GENE; ALLELIC IMBALANCE; AUTOPSY; CARDIOVASCULAR DISEASE; CENTRAL NERVOUS SYSTEM DISEASE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; POLYMERASE CHAIN REACTION;

ALLELIC IMBALANCE; AUTOPSY; CARDIOVASCULAR DISEASES; CENTRAL NERVOUS SYSTEM DISEASES; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; PHARMACOGENETICS; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS (GENETICS); RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

EID: 53049101481     PISSN: 17446872     EISSN: 17446880     Source Type: Journal    
DOI: 10.1097/FPC.0b013e3283050107     Document Type: Article

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