Dominant-negative effects of the N-terminal half of prion protein on neurotoxicity of prion protein-like protein/doppel in mice

Journal of Biological Chemistry

Volumn 283, Issue 35, 2008, Pages 24202-24211

  Yoshikawa, Daisuke ^a   Yamaguchi, Naohiro ^a   Ishibashi, Daisuke ^a   Yamanaka, Hitoki ^b   Okimura, Nobuhiko ^a   Yamaguchi, Yoshitaka ^c   Mori, Tsuyoshi ^c   Miyata, Hironori ^d   Shigematsu, Kazuto ^a   Katamine, Shigeru ^a   Sakaguchi, Suehiro ^a,b,c  

^a NAGASAKI UNIVERSITY GRADUATE SCHOOL OF BIOMEDICAL SCIENCES   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c UNIVERSITY OF TOKUSHIMA   (Japan)

^d UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID SEQUENCES; ANTAGONISTIC FUNCTIONS; FUSION PROTEINS; NEURODEGENERATION; NEUROTOXICITY; PRION PROTEINS; PURKINJE CELLS; TRANSGENIC MOUSE;

AMINES; AMINO ACIDS; CELL DEATH; NEURONS; ORGANIC ACIDS;

PORT TERMINALS;

HYBRID PROTEIN; PRION PROTEIN; PROTEIN DOPPEL; UNCLASSIFIED DRUG; PRND PROTEIN, MOUSE;

ARTICLE; ATAXIA; CELL DEGENERATION; CONTROLLED STUDY; MOUSE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PURKINJE CELL; ANIMAL; BIOSYNTHESIS; DEGENERATIVE DISEASE; GENETICS; HUMAN; METABOLISM; PATHOLOGY; PRION; PROTEIN TERTIARY STRUCTURE; TRANSGENIC MOUSE;

MUS; MUS MUSCULUS;

ANIMALS; ATAXIA; HUMANS; MICE; MICE, TRANSGENIC; NEURODEGENERATIVE DISEASES; PRIONS; PROTEIN STRUCTURE, TERTIARY; PURKINJE CELLS; RECOMBINANT FUSION PROTEINS;

EID: 53049087145     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M804212200     Document Type: Article

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