-
2
-
-
0030498975
-
Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation
-
Wang JH, Nichogiannopoulou A, Wu L et al. Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation. Immunity 1996;5:537-49.
-
(1996)
Immunity
, vol.5
, pp. 537-549
-
-
Wang, J.H.1
Nichogiannopoulou, A.2
Wu, L.3
-
3
-
-
0032745697
-
Pre-T cell receptor (TCR) and TCR-controlled checkpoints in T cell differentiation are set by Ikaros
-
Winandy S, Wu L, Wang JH, Georgopoulos K. Pre-T cell receptor (TCR) and TCR-controlled checkpoints in T cell differentiation are set by Ikaros. J Exp Med 1999;190:1039-48.
-
(1999)
J Exp Med
, vol.190
, pp. 1039-1048
-
-
Winandy, S.1
Wu, L.2
Wang, J.H.3
Georgopoulos, K.4
-
4
-
-
0028001362
-
The Ikaros gene is required for the development of all lymphoid lineages
-
Georgopoulos K, Bigby M, Wang JH et al. The Ikaros gene is required for the development of all lymphoid lineages. Cell 1994;79:143-56.
-
(1994)
Cell
, vol.79
, pp. 143-156
-
-
Georgopoulos, K.1
Bigby, M.2
Wang, J.H.3
-
5
-
-
0030972497
-
Aiolos, a lymphoid restricted transcription factor that interacts with Ikaros to regulate lymphocyte differentiation
-
Morgan B, Sun L, Avitahl N et al. Aiolos, a lymphoid restricted transcription factor that interacts with Ikaros to regulate lymphocyte differentiation. EMBO J 1997;16:2004-13.
-
(1997)
EMBO J
, vol.16
, pp. 2004-2013
-
-
Morgan, B.1
Sun, L.2
Avitahl, N.3
-
6
-
-
0032560018
-
Helios, a novel dimerization partner of Ikaros expressed in the earliest hematopoietic progenitors
-
Kelley CM, Ikeda T, Koipally J et al. Helios, a novel dimerization partner of Ikaros expressed in the earliest hematopoietic progenitors. Curr Biol 1998;8:508-515.
-
(1998)
Curr Biol
, vol.8
, pp. 508-515
-
-
Kelley, C.M.1
Ikeda, T.2
Koipally, J.3
-
7
-
-
15144358621
-
Helios, a T cell-restricted Ikaros family member that quantitatively associates with Ikaros at centromeric heterochromatin
-
Hahm K, Cobb BS, McCarty AS et al. Helios, a T cell-restricted Ikaros family member that quantitatively associates with Ikaros at centromeric heterochromatin. Genes Dev 1998;12:782-96.
-
(1998)
Genes Dev
, vol.12
, pp. 782-796
-
-
Hahm, K.1
Cobb, B.S.2
McCarty, A.S.3
-
8
-
-
0028866897
-
A dominant mutation in the Ikaros gene leads to rapid development of leukemia and lymphoma
-
Winandy S, Wu P, Georgopoulos K. A dominant mutation in the Ikaros gene leads to rapid development of leukemia and lymphoma. Cell 1995;83:289-99.
-
(1995)
Cell
, vol.83
, pp. 289-299
-
-
Winandy, S.1
Wu, P.2
Georgopoulos, K.3
-
9
-
-
0033103013
-
Ikaros sets thresholds for T cell activation and regulates chromosome propagation
-
Avitahl N, Winandy S, Friedrich C, Jones B, Ge Y, Georgopoulos K. Ikaros sets thresholds for T cell activation and regulates chromosome propagation. Immunity 1999;10:333-43.
-
(1999)
Immunity
, vol.10
, pp. 333-343
-
-
Avitahl, N.1
Winandy, S.2
Friedrich, C.3
Jones, B.4
Ge, Y.5
Georgopoulos, K.6
-
10
-
-
0032246451
-
The cytogenesis and pathogenesis of pituitary adenomas
-
Asa SL, Ezzat S. The cytogenesis and pathogenesis of pituitary adenomas. Endocr Rev 1998;19:798-827.
-
(1998)
Endocr Rev
, vol.19
, pp. 798-827
-
-
Asa, S.L.1
Ezzat, S.2
-
11
-
-
0033123174
-
Molecular determinants of pituitary cytodifferentiation
-
Asa SL, Ezzat S. Molecular determinants of pituitary cytodifferentiation. Pituitary 1999;1:159-68.
-
(1999)
Pituitary
, vol.1
, pp. 159-168
-
-
Asa, S.L.1
Ezzat, S.2
-
12
-
-
0036831826
-
The pathogenesis of pituitary tumours
-
Asa SL, Ezzat S. The pathogenesis of pituitary tumours. Nat Rev Cancer 2002;2:836-49.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 836-849
-
-
Asa, S.L.1
Ezzat, S.2
-
13
-
-
0030044364
-
The Ikaros gene encodes a family of lymphocyte-restricted zinc finger DNA binding proteins, highly conserved in human and mouse
-
Molnar A, Wu P, Largespada DA et al. The Ikaros gene encodes a family of lymphocyte-restricted zinc finger DNA binding proteins, highly conserved in human and mouse. J Immunol 1996;156:585-92.
-
(1996)
J Immunol
, vol.156
, pp. 585-592
-
-
Molnar, A.1
Wu, P.2
Largespada, D.A.3
-
14
-
-
0030933151
-
The role of the Ikaros gene in lymphocyte development and homeostasis
-
Georgopoulos K, Winandy S, Avitahl N. The role of the Ikaros gene in lymphocyte development and homeostasis. Annu Rev Immunol 1997;15:155-76.
-
(1997)
Annu Rev Immunol
, vol.15
, pp. 155-176
-
-
Georgopoulos, K.1
Winandy, S.2
Avitahl, N.3
-
15
-
-
16844373321
-
Ikaros integrates endocrine and immune system development
-
Ezzat S, Mader R, Yu S, Ning T, Poussier P, Asa SL. Ikaros integrates endocrine and immune system development. J Clin Invest 2005;115:1021-9.
-
(2005)
J Clin Invest
, vol.115
, pp. 1021-1029
-
-
Ezzat, S.1
Mader, R.2
Yu, S.3
Ning, T.4
Poussier, P.5
Asa, S.L.6
-
16
-
-
0028019274
-
The Ikaros gene encodes a family of functionally diverse zinc finger DNA-binding proteins
-
Molnar A, Georgopoulos K. The Ikaros gene encodes a family of functionally diverse zinc finger DNA-binding proteins. Mol Cell Biol 1994;14:8292-303.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 8292-8303
-
-
Molnar, A.1
Georgopoulos, K.2
-
17
-
-
0029831978
-
Zinc finger-mediated protein interactions modulate Ikaros activity, a molecular control of lymphocyte development
-
Sun L, Liu A, Georgopoulos K. Zinc finger-mediated protein interactions modulate Ikaros activity, a molecular control of lymphocyte development. EMBO J 1996;15:5358-69.
-
(1996)
EMBO J
, vol.15
, pp. 5358-5369
-
-
Sun, L.1
Liu, A.2
Georgopoulos, K.3
-
18
-
-
0028152483
-
The lymphoid transcription factor LyF-1 is encoded by specific, alternatively spliced mRNAs derived from the Ikaros gene
-
Hahm K, Ernst P, Lo K, Kim GS, Turck C, Smale ST. The lymphoid transcription factor LyF-1 is encoded by specific, alternatively spliced mRNAs derived from the Ikaros gene. Mol Cell Biol 1994;14:7111-23.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 7111-7123
-
-
Hahm, K.1
Ernst, P.2
Lo, K.3
Kim, G.S.4
Turck, C.5
Smale, S.T.6
-
19
-
-
0033870658
-
Dominant negative isoform of the Ikaros gene in patients with adult B-cell acute lymphoblastic leukemia
-
Nakase K, Ishimaru F, Avitahl N et al. Dominant negative isoform of the Ikaros gene in patients with adult B-cell acute lymphoblastic leukemia. Cancer Res 2000:60:4062-5.
-
(2000)
Cancer Res
, vol.60
, pp. 4062-4065
-
-
Nakase, K.1
Ishimaru, F.2
Avitahl, N.3
-
20
-
-
0033231420
-
Defects in hemopoietic stem cell activity in Ikaros mutant mice
-
Nichogiannopoulou A, Trevisan M, Neben S, Friedrich C, Georgopoulos K. Defects in hemopoietic stem cell activity in Ikaros mutant mice. J Exp Med 1999;190:1201-14.
-
(1999)
J Exp Med
, vol.190
, pp. 1201-1214
-
-
Nichogiannopoulou, A.1
Trevisan, M.2
Neben, S.3
Friedrich, C.4
Georgopoulos, K.5
-
21
-
-
0041924034
-
Ikaros isoforms in human pituitary tumors: Distinct localization, histone acetylation, and activation of the 5′ fibroblast growth factor receptor-4 promoter
-
Ezzat S, Yu S, Asa SL. Ikaros isoforms in human pituitary tumors: distinct localization, histone acetylation, and activation of the 5′ fibroblast growth factor receptor-4 promoter. Am J Pathol 2003;163:1177-84.
-
(2003)
Am J Pathol
, vol.163
, pp. 1177-1184
-
-
Ezzat, S.1
Yu, S.2
Asa, S.L.3
-
22
-
-
33751520959
-
Tumor-Derived Ikaros 6 Acetylates the Bcl-XL Promoter to Up-Regulate a Survival Signal in Pituitary Cells
-
Ezzat S, Zhu X, Loeper S, Fischer S, Asa SL. Tumor-Derived Ikaros 6 Acetylates the Bcl-XL Promoter to Up-Regulate a Survival Signal in Pituitary Cells. Mol Endocrinol 2006;20:2976-86.
-
(2006)
Mol Endocrinol
, vol.20
, pp. 2976-2986
-
-
Ezzat, S.1
Zhu, X.2
Loeper, S.3
Fischer, S.4
Asa, S.L.5
-
23
-
-
45549101308
-
Ikaros Modulates Cholesterol Uptake: A Link Between Tumor Suppression and Differentiation
-
Loeper S, Asa SL, Ezzat S. Ikaros Modulates Cholesterol Uptake: A Link Between Tumor Suppression and Differentiation. Cancer Res 2008;68:3715-23.
-
(2008)
Cancer Res
, vol.68
, pp. 3715-3723
-
-
Loeper, S.1
Asa, S.L.2
Ezzat, S.3
-
24
-
-
0033544935
-
Pit-1 binding sites at the somatotrope-specific DNase I hypersensitive sites I, II of the human growth hormone locus control region are essential for in vivo hGH-N gene activation
-
Shewchuk BM, Asa SL, Cooke NE, Liebhaber SA. Pit-1 binding sites at the somatotrope-specific DNase I hypersensitive sites I, II of the human growth hormone locus control region are essential for in vivo hGH-N gene activation. J Biol Chem 1999;274:35725-33.
-
(1999)
J Biol Chem
, vol.274
, pp. 35725-35733
-
-
Shewchuk, B.M.1
Asa, S.L.2
Cooke, N.E.3
Liebhaber, S.A.4
-
25
-
-
0035937414
-
A pituitary cell-restricted T box factor, Tpit, activates POMC transcription in cooperation with Pitx homeoproteins
-
Lamolet B, Pulichino AM, Lamonerie T et al. A pituitary cell-restricted T box factor, Tpit, activates POMC transcription in cooperation with Pitx homeoproteins. Cell 2001;104:849-59.
-
(2001)
Cell
, vol.104
, pp. 849-859
-
-
Lamolet, B.1
Pulichino, A.M.2
Lamonerie, T.3
-
26
-
-
0344875578
-
The T-box factor Tpit recruits SRC/p160 co-activators and mediates hormone action
-
Maira M, Couture C, Le Martelot G, Pulichino AM, Bilodeau S, Drouin J. The T-box factor Tpit recruits SRC/p160 co-activators and mediates hormone action. J Biol Chem 2003;278:46523-32.
-
(2003)
J Biol Chem
, vol.278
, pp. 46523-46532
-
-
Maira, M.1
Couture, C.2
Le Martelot, G.3
Pulichino, A.M.4
Bilodeau, S.5
Drouin, J.6
-
27
-
-
33144458192
-
An essential role for the hematopoietic transcription factor Ikaros in hypothalamic-pituitary- mediated somatic growth
-
Ezzat S, Mader R, Fischer S, Yu S, Ackerley C, Asa SL. An essential role for the hematopoietic transcription factor Ikaros in hypothalamic-pituitary- mediated somatic growth. Proc Natl Acad Sci U S A 2006;103:2214-9.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 2214-2219
-
-
Ezzat, S.1
Mader, R.2
Fischer, S.3
Yu, S.4
Ackerley, C.5
Asa, S.L.6
-
28
-
-
15444368750
-
The zinc finger Ikaros transcription factor regulates pituitary growth hormone and prolactin gene expression through distinct effects on chromatin accessibility
-
Ezzat S, Yu S, Asa SL. The zinc finger Ikaros transcription factor regulates pituitary growth hormone and prolactin gene expression through distinct effects on chromatin accessibility. Mol Endocrinol 2005;19:1004-11.
-
(2005)
Mol Endocrinol
, vol.19
, pp. 1004-1011
-
-
Ezzat, S.1
Yu, S.2
Asa, S.L.3
-
29
-
-
34548220856
-
Ikaros is expressed in developing striatal neurons and involved in enkephalinergic differentiation
-
Agoston DV, Szemes M, Dobi A et al. Ikaros is expressed in developing striatal neurons and involved in enkephalinergic differentiation. J Neurochem 2007;102:1805-16.
-
(2007)
J Neurochem
, vol.102
, pp. 1805-1816
-
-
Agoston, D.V.1
Szemes, M.2
Dobi, A.3
-
31
-
-
42749095317
-
Mice lacking the transcription factor Ikaros display behavioral alterations of an anti-depressive phenotype
-
Kiehl TR, Fischer SE, Ezzat S, Asa SL. Mice lacking the transcription factor Ikaros display behavioral alterations of an anti-depressive phenotype. Exp Neurol 2008;211:107-14.
-
(2008)
Exp Neurol
, vol.211
, pp. 107-114
-
-
Kiehl, T.R.1
Fischer, S.E.2
Ezzat, S.3
Asa, S.L.4
|