The role of muscarinic receptor subtypes in acetylcholine release from urinary bladder obtained from muscarinic receptor knockout mouse

Neuroscience

Volumn 156, Issue 2, 2008, Pages 381-389

  Takeuchi, T ^a   Yamashiro, N ^a   Kawasaki, T ^a   Nakajima, H ^a   Azuma, Y T ^a   Matsui, M ^b  

^a Osaka City University   (Japan)

^b CHIBA INSTITUTE OF SCIENCE   (Japan)

Author keywords

acetylcholine release; M4 receptor subtype; mouse bladder; muscarinic knockout mice; prejunctional inhibitory muscarinic receptor

Indexed keywords

ACETYLCHOLINE; CHOLINE ACETYLTRANSFERASE; MUSCARINIC M1 RECEPTOR; MUSCARINIC M2 RECEPTOR; MUSCARINIC M3 RECEPTOR; MUSCARINIC M4 RECEPTOR; MUSCARINIC M5 RECEPTOR;

ACETYLCHOLINE RELEASE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLADDER; BLADDER CONTRACTION; CONTROLLED STUDY; ELECTROSTIMULATION; ENZYME LOCALIZATION; FEMALE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMOOTH MUSCLE FIBER;

ACETYLCHOLINE; ADENOSINE TRIPHOSPHATE; ANESTHETICS, LOCAL; ANIMALS; ATROPINE; CHOLINE O-ACETYLTRANSFERASE; DOSE-RESPONSE RELATIONSHIP, RADIATION; ELECTRIC STIMULATION; FEMALE; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUSCARINIC ANTAGONISTS; MUSCLE CONTRACTION; MUSCLES; RECEPTORS, MUSCARINIC; RNA, MESSENGER; TETRODOTOXIN; URINARY BLADDER;

EID: 52949147142     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2008.07.056     Document Type: Article

References (33)

1. Alberts P. Classification of the presynaptic muscarinic receptor subtype that regulates 3H-acetylcholine secretion in the guinea pig urinary bladder in vitro. J Pharmacol Exp Ther 274 (1995) 458-468
2. Andersson K.E., and Arner A. Urinary bladder contraction and relaxation: physiology and pathophysiology. Physiol Rev 84 (2004) 935-986
3. Braverman A.S., Kohn I.J., Luthin G.R., and Ruggieri M.R. Prejunctional M1 facilitory and M2 inhibitory muscarinic receptors mediate rat bladder contractility. Am J Physiol 274 (1998) R517-R523
4. Braverman A.S., Tibb A.S., and Ruggieri Sr. M.R. M2 and M3 muscarinic receptor activation of urinary bladder contractile signal transduction. I. Normal rat bladder. J Pharmacol Exp Ther 316 (2006) 869-874
5. Caulfield M.P., and Birdsall N.J. International Union of Pharmacology. XVII. Classification of muscarinic acetylcholine receptors. Pharmacol Rev 50 (1998) 279-290
6. D'Agostino G., Barbieri A., Chiossa E., and Tonini M. M4 muscarinic autoreceptor-mediated inhibition of -3H-acetylcholine release in the rat isolated urinary bladder. J Pharmacol Exp Ther 283 (1997) 750-756
7. D'Agostino G., Bolognesi M.L., Lucchelli A., Vicini D., Balestra B., Spelta V., Melchiorre C., and Tonini M. Prejunctional muscarinic inhibitory control of acetylcholine release in the human isolated detrusor: involvement of the M4 receptor subtype. Br J Pharmacol 129 (2000) 493-500
8. de Groat W.C., and Yoshimura N. Pharmacology of the lower urinary tract. Annu Rev Pharmacol Toxicol 41 (2001) 691-721
9. Ehlert F.J., Ahn S., Pak K.J., Park G.J., Sangnil M.S., Tran J.A., and Matsui M. Neuronally released acetylcholine acts on the M2 muscarinic receptor to oppose the relaxant effect of isoproterenol on cholinergic contractions in mouse urinary bladder. J Pharmacol Exp Ther 322 (2007) 631-637
10. Ekman M., Andersson K.E., and Arner A. Developmental regulation of nerve and receptor mediated contractions of mammalian urinary bladder smooth muscle. Eur J Pharmacol 532 (2006) 99-106
11. Fetscher C., Fleichman M., Schmidt M., Krege S., and Michel M.C. M(3) muscarinic receptors mediate contraction of human urinary bladder. Br J Pharmacol 136 (2002) 641-643
12. Fukudome Y., Ohno-Shosaku T., Matsui M., Omori Y., Fukaya M., Tsubokawa H., Taketo M.M., Watanabe M., Manabe T., and Kano M. Two distinct classes of muscarinic action on hippocampal inhibitory synapses: M2-mediated direct suppression and M1/M3-mediated indirect suppression through endocannabinoid signalling. Eur J Neurosci 19 (2004) 2682-2692
13. Hegde S.S. Muscarinic receptors in the bladder: from basic research to therapeutics. Br J Pharmacol 147 Suppl 2 (2006) S80-S87
14. Hegde S.S., Choppin A., Bonhaus D., Briaud S., Loeb M., Moy T.M., Loury D., and Eglen R.M. Functional role of M2 and M3 muscarinic receptors in the urinary bladder of rats in vitro and in vivo. Br J Pharmacol 120 (1997) 1409-1418
15. Hegde S.S., and Eglen R.M. Muscarinic receptor subtypes modulating smooth muscle contractility in the urinary bladder. Life Sci 64 (1999) 419-428
16. Inadome A., Yoshida M., Takahashi W., Yono M., Seshita H., Miyamoto Y., Kawano T., and Ueda S. Prejunctional muscarinic receptors modulating acetylcholine release in rabbit detrusor smooth muscles. Urol Int 61 (1998) 135-141
17. Karasawa H., Taketo M.M., and Matsui M. Loss of anti-cataleptic effect of scopolamine in mice lacking muscarinic acetylcholine receptor subtype 4. Eur J Pharmacol 468 (2003) 15-19
18. Mansfield K.J., Liu L., Mitchelson F.J., Moore K.H., Millard R.J., and Burcher E. Muscarinic receptor subtypes in human bladder detrusor and mucosa, studied by radioligand binding and quantitative competitive RT-PCR: changes in ageing. Br J Pharmacol 144 (2005) 1089-1099
19. Matsui M., Motomura D., Fujikawa T., Jiang J., Takahashi S., Manabe T., and Taketo M.M. Mice lacking M2 and M3 muscarinic acetylcholine receptors are devoid of cholinergic smooth muscle contractions but still viable. J Neurosci 22 (2002) 10627-10632
20. Matsui M., Motomura D., Karasawa H., Fujikawa T., Jiang J., Komiya Y., Takahashi S., and Taketo M.M. Multiple functional defects in peripheral autonomic organs in mice lacking muscarinic acetylcholine receptor gene for the M3 subtype. Proc Natl Acad Sci U S A 97 (2000) 9579-9584
21. Nakamura T., Matsui M., Uchida K., Futatsugi A., Kusakawa S., Matsumoto N., Nakamura K., Manabe T., Taketo M.M., and Mikoshiba K. M(3) muscarinic acetylcholine receptor plays a critical role in parasympathetic control of salivation in mice. J Physiol 558 (2004) 561-575
22. Ohno-Shosaku T., Matsui M., Fukudome Y., Shosaku J., Tsubokawa H., Taketo M.M., Manabe T., and Kano M. Postsynaptic M1 and M3 receptors are responsible for the muscarinic enhancement of retrograde endocannabinoid signalling in the hippocampus. Eur J Neurosci 18 (2003) 109-116
23. Shen A., and Mitchelson F. Characterisation of the prejunctional inhibitory muscarinic receptor on cholinergic nerves in the rat urinary bladder. Eur J Pharmacol 413 (2001) 179-187
24. Somogyi G.T., Tanowitz M., and de Groat W.C. M1 muscarinic receptor-mediated facilitation of acetylcholine release in the rat urinary bladder. J Physiol 480 Pt 1 (1994) 81-89
25. Takeuchi T., Fujinami K., Goto H., Fujita A., Taketo M.M., Manabe T., Matsui M., and Hata F. Roles of M2 and M4 muscarinic receptors in regulating acetylcholine release from myenteric neurons of mouse ileum. J Neurophysiol 93 (2005) 2841-2848
26. Tobin G., and Sjogren C. Prejunctional facilitatory and inhibitory modulation of parasympathetic nerve transmission in the rabbit urinary bladder. J Auton Nerv Syst 68 (1998) 153-156
27. Tyagi S., Tyagi P., Van-le S., Yoshimura N., Chancellor M.B., and de Miguel F. Qualitative and quantitative expression profile of muscarinic receptors in human urothelium and detrusor. J Urol 176 (2006) 1673-1678
28. Wess J. Muscarinic acetylcholine receptor knockout mice: novel phenotypes and clinical implications. Annu Rev Pharmacol Toxicol 44 (2004) 423-450
29. Yamada M., Basile A.S., Fedorova I., Zhang W., Duttaroy A., Cui Y., Lamping K.G., Faraci F.M., Deng C.X., and Wess J. Novel insights into M5 muscarinic acetylcholine receptor function by the use of gene targeting technology. Life Sci 74 (2003) 345-353
30. Zarghooni S., Wunsch J., Bodenbenner M., Bruggmann D., Grando S.A., Schwantes U., Wess J., Kummer W., and Lips K.S. Expression of muscarinic and nicotinic acetylcholine receptors in the mouse urothelium. Life Sci 80 (2007) 2308-2313
31. Zhang H.M., Chen S.R., Matsui M., Gautam D., Wess J., and Pan H.L. Opposing functions of spinal M2, M3, and M4 receptor subtypes in regulation of GABAergic inputs to dorsal horn neurons revealed by muscarinic receptor knockout mice. Mol Pharmacol 69 (2006) 1048-1055
32. Zhang H.M., Li D.P., Chen S.R., and Pan H.L. M2, M3, and M4 receptor subtypes contribute to muscarinic potentiation of GABAergic inputs to spinal dorsal horn neurons. J Pharmacol Exp Ther 313 (2005) 697-704
33. Zhou H., Meyer A., Starke K., Gomeza J., Wess J., and Trendelenburg A.U. Heterogeneity of release-inhibiting muscarinic autoreceptors in heart atria and urinary bladder: a study with M(2)- and M(4)-receptor-deficient mice. Naunyn Schmiedebergs Arch Pharmacol 365 (2002) 112-122