Mpv17l protects against mitochondrial oxidative stress and apoptosis by activation of Omi/HtrA2 protease

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 37, 2008, Pages 14106-14111

  Krick, Stefanie ^a   Shi, Shaolin ^a   Ju, Wenjun ^a   Faul, Christian ^a   Tsai, Su Yi ^a   Mundel, Peter ^a   Böttinger, Erwin P ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Hypoxia; Kidney injury; Proximal tubular epithelial cells; Reactive oxygen species; Transforming growth factor beta

Indexed keywords

MEMBRANE PROTEIN; MPV 17I PROTEIN; PDZ PROTEIN; SERINE PROTEINASE OMI; SUPEROXIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELLULAR STRESS SIGNAL; ENZYME ACTIVATION; ENZYME REGULATION; KIDNEY INJURY; KIDNEY PROXIMAL TUBULE; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN SYNTHESIS INHIBITION; PROTEIN SYNTHESIS REGULATION;

ANIMALS; ANTIMYCIN A; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BINDING SITES; CELL LINE; CERCOPITHECUS AETHIOPS; DISEASE PROGRESSION; DOWN-REGULATION; ENZYME ACTIVATION; HUMANS; KIDNEY DISEASES; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; MICROSCOPY, ELECTRON; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; OXIDATIVE STRESS; PROTEIN ISOFORMS; REACTIVE OXYGEN SPECIES; SERINE ENDOPEPTIDASES;

EID: 52949142730     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0801146105     Document Type: Article

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