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Volumn 100, Issue 2, 2008, Pages 297-305

Physiological concentrations of short-chain fatty acids immediately suppress colonic epithelial permeability

Author keywords

Barrier function; Caco 2 cells; Caecum; SCFA; T84 cells; Tight junction

Indexed keywords

ACETIC ACID; BUTYRIC ACID; CHOLESTEROL; GUANINE NUCLEOTIDE BINDING PROTEIN; LUCIFER YELLOW; MANNITOL; MONOCARBOXYLATE TRANSPORTER 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROPIONIC ACID; SHORT CHAIN FATTY ACID; TRITIUM;

EID: 52949134856     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114508888733     Document Type: Article
Times cited : (280)

References (42)
  • 1
    • 22444447674 scopus 로고    scopus 로고
    • Dose-dependent stimulatory and inhibitory effects of luminal and serosal n-butyric acid on epithelial cell proliferation of pig distal colonic mucosa
    • Inagaki A & Sakata T (2005) Dose-dependent stimulatory and inhibitory effects of luminal and serosal n-butyric acid on epithelial cell proliferation of pig distal colonic mucosa. J Nutr Sci Vitaminol (Tokyo) 51, 1561-160.
    • (2005) J Nutr Sci Vitaminol (Tokyo) , vol.51 , pp. 1561-2160
    • Inagaki, A.1    Sakata, T.2
  • 2
    • 0029286528 scopus 로고
    • Effect of n butyric acid on epithelial cell proliferation of pig colonic mucosa in short-term culture
    • Sakata T, Adachi M, Hashida M, Sato N & Kojima T (1995) Effect of n butyric acid on epithelial cell proliferation of pig colonic mucosa in short-term culture. Dtsch Tierarztl Wochenschr 102, 163-164.
    • (1995) Dtsch Tierarztl Wochenschr , vol.102 , pp. 163-164
    • Sakata, T.1    Adachi, M.2    Hashida, M.3    Sato, N.4    Kojima, T.5
  • 3
    • 0030069609 scopus 로고    scopus 로고
    • Mechanism of butyrate-induced vasorelaxation of rat mesenteric resistance artery
    • Aaronson PI, McKinnon W & Poston L (1996) Mechanism of butyrate-induced vasorelaxation of rat mesenteric resistance artery. Br J Pharmacol 117, 365-371.
    • (1996) Br J Pharmacol , vol.117 , pp. 365-371
    • Aaronson, P.I.1    McKinnon, W.2    Poston, L.3
  • 5
    • 0036486708 scopus 로고    scopus 로고
    • Effect of short-chain fatty acids on contraction of smooth muscle in the canine colon
    • McManus CM, Michel KE, Simon DM & Washabau RJ (2002) Effect of short-chain fatty acids on contraction of smooth muscle in the canine colon. Am J Vet Res 63, 295-300.
    • (2002) Am J Vet Res , vol.63 , pp. 295-300
    • McManus, C.M.1    Michel, K.E.2    Simon, D.M.3    Washabau, R.J.4
  • 6
    • 0028844444 scopus 로고
    • Kinetic studies on colonocyte metabolism of short chain fatty acids and glucose in ulcerative colitis
    • Clausen MR & Mortensen PB (1995) Kinetic studies on colonocyte metabolism of short chain fatty acids and glucose in ulcerative colitis. Gut 37, 684-689.
    • (1995) Gut , vol.37 , pp. 684-689
    • Clausen, M.R.1    Mortensen, P.B.2
  • 7
    • 0028084517 scopus 로고
    • Kinetic studies on the metabolism of short-chain fatty acids and glucose by isolated rat colonocytes
    • Clausen MR & Mortensen PB (1994) Kinetic studies on the metabolism of short-chain fatty acids and glucose by isolated rat colonocytes. Gastroenterology 106, 423-432.
    • (1994) Gastroenterology , vol.106 , pp. 423-432
    • Clausen, M.R.1    Mortensen, P.B.2
  • 8
    • 33846707942 scopus 로고    scopus 로고
    • Valproic acid and butyrate induce apoptosis in human cancer cells through inhibition of gene expression of Akt/protein kinase B
    • Chen J, Ghazawi FM, Bakkar W & Li Q (2006) Valproic acid and butyrate induce apoptosis in human cancer cells through inhibition of gene expression of Akt/protein kinase B. Mol Cancer 5, 71.
    • (2006) Mol Cancer , vol.5 , pp. 71
    • Chen, J.1    Ghazawi, F.M.2    Bakkar, W.3    Li, Q.4
  • 9
    • 34347251597 scopus 로고    scopus 로고
    • Docosahexaenoic acid and butyrate synergistically induce colonocyte apoptosis by enhancing mitochondrial Ca2 + accumulation
    • Kolar SS, Barhoumi R, Lupton JR & Chapkin RS (2007) Docosahexaenoic acid and butyrate synergistically induce colonocyte apoptosis by enhancing mitochondrial Ca2 + accumulation. Cancer Res 67, 5561-5568.
    • (2007) Cancer Res , vol.67 , pp. 5561-5568
    • Kolar, S.S.1    Barhoumi, R.2    Lupton, J.R.3    Chapkin, R.S.4
  • 10
    • 0032577975 scopus 로고    scopus 로고
    • Claudin-1 and -2: Novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin
    • Furuse M, Fujita K, Hiiragi T, Fujimoto K & Tsukita S (1998) Claudin-1 and -2: Novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin. J Cell Biol 141, 1539-1550.
    • (1998) J Cell Biol , vol.141 , pp. 1539-1550
    • Furuse, M.1    Fujita, K.2    Hiiragi, T.3    Fujimoto, K.4    Tsukita, S.5
  • 13
    • 0033681151 scopus 로고    scopus 로고
    • Molecular physiology and pathophysiology of tight junctions III. Tight junction regulation by intracellular messengers: Differences in response within and between epithelia
    • Karczewski J & Groot J (2000) Molecular physiology and pathophysiology of tight junctions III. Tight junction regulation by intracellular messengers: Differences in response within and between epithelia. Am J Physiol Gastrointest Liver Physiol 279, G660-G665.
    • (2000) Am J Physiol Gastrointest Liver Physiol , vol.279
    • Karczewski, J.1    Groot, J.2
  • 14
    • 0031885344 scopus 로고    scopus 로고
    • Absorption enhancement through intracellular regulation of tight junction permeability by medium chain fatty acids in CaCo-2 cells
    • Lindmark T, Kimura Y & Artursson P (1998) Absorption enhancement through intracellular regulation of tight junction permeability by medium chain fatty acids in CaCo-2 cells. J Pharmacol Exp Ther 284, 362-369.
    • (1998) J Pharmacol Exp Ther , vol.284 , pp. 362-369
    • Lindmark, T.1    Kimura, Y.2    Artursson, P.3
  • 15
    • 0036846448 scopus 로고    scopus 로고
    • Melibiose, difructose anhydride III and difructose anhydride IV enhance net calcium absorption in rat small and large intestinal epithelium by increasing the passage of tight junctions in vitro
    • Mineo H, Hara H, Shigematsu N, Okuhara Y & Tomita F (2002) Melibiose, difructose anhydride III and difructose anhydride IV enhance net calcium absorption in rat small and large intestinal epithelium by increasing the passage of tight junctions in vitro. J Nutr 132, 3394-3399.
    • (2002) J Nutr , vol.132 , pp. 3394-3399
    • Mineo, H.1    Hara, H.2    Shigematsu, N.3    Okuhara, Y.4    Tomita, F.5
  • 16
    • 33745794946 scopus 로고    scopus 로고
    • Difructose anhydride III and sodium caprate activate paracellular transport via different intracellular events in Caco-2 cells
    • Suzuki T & Hara H (2006) Difructose anhydride III and sodium caprate activate paracellular transport via different intracellular events in Caco-2 cells. Life Sci 79, 401-410.
    • (2006) Life Sci , vol.79 , pp. 401-410
    • Suzuki, T.1    Hara, H.2
  • 17
    • 0030926950 scopus 로고    scopus 로고
    • Effect of short-chain fatty acids on paracellular permeability in Caco-2 intestinal epithelium model
    • Mariadason JM, Barkla DH & Gibson PR (1997) Effect of short-chain fatty acids on paracellular permeability in Caco-2 intestinal epithelium model. Am J Physiol 272, G705-G712.
    • (1997) Am J Physiol , vol.272
    • Mariadason, J.M.1    Barkla, D.H.2    Gibson, P.R.3
  • 18
    • 21644484477 scopus 로고    scopus 로고
    • Differentiation of human colon adenocarcinoma cells alters the expression and intracellular localization of annexins A1, A2, and A5
    • Guzman-Aranguez A, Olmo N, Turnay J, Lecona E, Perez-Ramos P, Lopez de Silanes I & Lizarbe MA (2005) Differentiation of human colon adenocarcinoma cells alters the expression and intracellular localization of annexins A1, A2, and A5. J Cell Biochem 94, 178-193.
    • (2005) J Cell Biochem , vol.94 , pp. 178-193
    • Guzman-Aranguez, A.1    Olmo, N.2    Turnay, J.3    Lecona, E.4    Perez-Ramos, P.5    Lopez de Silanes, I.6    Lizarbe, M.A.7
  • 19
    • 33847636305 scopus 로고    scopus 로고
    • The induction of colonocyte differentiation in CaCo-2 cells by sodium butyrate causes an increase in glucosylceramide synthesis in order to avoid apoptosis based on ceramide
    • Yamane M & Yamane S (2007) The induction of colonocyte differentiation in CaCo-2 cells by sodium butyrate causes an increase in glucosylceramide synthesis in order to avoid apoptosis based on ceramide. Arch Biochem Biophys 459, 159-168.
    • (2007) Arch Biochem Biophys , vol.459 , pp. 159-168
    • Yamane, M.1    Yamane, S.2
  • 20
    • 32944482363 scopus 로고    scopus 로고
    • Two-week feeding of difructose anhydride III enhances calcium absorptive activity with epithelial cell proliferation in isolated rat cecal mucosa
    • Mineo H, Amano M, Minaminida K, Chiji H, Shigematsu N, Tomita F & Hara H (2006) Two-week feeding of difructose anhydride III enhances calcium absorptive activity with epithelial cell proliferation in isolated rat cecal mucosa. Nutrition 22, 312-320.
    • (2006) Nutrition , vol.22 , pp. 312-320
    • Mineo, H.1    Amano, M.2    Minaminida, K.3    Chiji, H.4    Shigematsu, N.5    Tomita, F.6    Hara, H.7
  • 21
    • 0032925303 scopus 로고    scopus 로고
    • Ingestion of guar gum hydrolysate, a soluble fiber, increases calcium absorption in totally gastrectomized rats
    • Hara H, Suzuki T, Kasai T, Aoyama Y & Ohta A (1999) Ingestion of guar gum hydrolysate, a soluble fiber, increases calcium absorption in totally gastrectomized rats. J Nutr 129, 39-45.
    • (1999) J Nutr , vol.129 , pp. 39-45
    • Hara, H.1    Suzuki, T.2    Kasai, T.3    Aoyama, Y.4    Ohta, A.5
  • 22
    • 24644511076 scopus 로고    scopus 로고
    • Promotive effects of non-digestible disaccharides on rat mineral absorption depend on the type of saccharide
    • Asvarujanon P, Ishizuka S & Hara H (2005) Promotive effects of non-digestible disaccharides on rat mineral absorption depend on the type of saccharide. Nutrition 21, 1025-1035.
    • (2005) Nutrition , vol.21 , pp. 1025-1035
    • Asvarujanon, P.1    Ishizuka, S.2    Hara, H.3
  • 23
    • 33745641132 scopus 로고    scopus 로고
    • Effects of long-term ingestign of difructose anhydride III (DFA III) on intestinal bacteria and bile acid metabolism in humans
    • Minamida K, Asakawa C, Sujaya IN, Kaneko M, Abe A, Sone T, Hara H, Asano K & Tomita F (2006) Effects of long-term ingestign of difructose anhydride III (DFA III) on intestinal bacteria and bile acid metabolism in humans. J Biosci Bioeng 101, 149-156.
    • (2006) J Biosci Bioeng , vol.101 , pp. 149-156
    • Minamida, K.1    Asakawa, C.2    Sujaya, I.N.3    Kaneko, M.4    Abe, A.5    Sone, T.6    Hara, H.7    Asano, K.8    Tomita, F.9
  • 25
    • 0033766454 scopus 로고    scopus 로고
    • Substrate and inhibitor specificity of butyrate uptake in apical membrane vesicles of the rat distal colon
    • Schroder O, Opritz J & Stein J (2000) Substrate and inhibitor specificity of butyrate uptake in apical membrane vesicles of the rat distal colon. Digestion 62, 152-158.
    • (2000) Digestion , vol.62 , pp. 152-158
    • Schroder, O.1    Opritz, J.2    Stein, J.3
  • 26
    • 3543083376 scopus 로고    scopus 로고
    • Ingestion of guar gum hydrolysate, a soluble and fermentable nondigestible saccharide, improves glucose intolerance and prevents hypertriglyceridemia in rats fed fructose
    • Suzuki T & Hara H (2004) Ingestion of guar gum hydrolysate, a soluble and fermentable nondigestible saccharide, improves glucose intolerance and prevents hypertriglyceridemia in rats fed fructose. J Nutr 134, 1942-1947.
    • (2004) J Nutr , vol.134 , pp. 1942-1947
    • Suzuki, T.1    Hara, H.2
  • 27
    • 0000130569 scopus 로고
    • Multiple range and multiple F test
    • Duncan DB (1955) Multiple range and multiple F test. Biometrics 11, 1-42.
    • (1955) Biometrics , vol.11 , pp. 1-42
    • Duncan, D.B.1
  • 28
    • 33745797135 scopus 로고    scopus 로고
    • Regulation of the intestinal epithelial barrier by the apical junctional complex
    • Laukoetter MG, Bruewer M & Nusrat A (2006) Regulation of the intestinal epithelial barrier by the apical junctional complex. Curr Opin Gastroenterol 22, 85-89.
    • (2006) Curr Opin Gastroenterol , vol.22 , pp. 85-89
    • Laukoetter, M.G.1    Bruewer, M.2    Nusrat, A.3
  • 29
    • 34447281675 scopus 로고    scopus 로고
    • Molecular basis of epithelial barrier regulation: From basic mechanisms to clinical application
    • Turner JR (2006) Molecular basis of epithelial barrier regulation: From basic mechanisms to clinical application. Am J Pathol 169, 1901-1909.
    • (2006) Am J Pathol , vol.169 , pp. 1901-1909
    • Turner, J.R.1
  • 30
    • 23044512956 scopus 로고    scopus 로고
    • Neural and non-neural mediation of propionate-induced contractile responses in the rat distal colon
    • Mitsui R, Ono S, Karaki S & Kuwahara A (2005) Neural and non-neural mediation of propionate-induced contractile responses in the rat distal colon. Neurogastroenterol Motil 17, 585-594.
    • (2005) Neurogastroenterol Motil , vol.17 , pp. 585-594
    • Mitsui, R.1    Ono, S.2    Karaki, S.3    Kuwahara, A.4
  • 31
    • 0032888238 scopus 로고    scopus 로고
    • Effect of butyrate on paracellular permeability in rat distal colonic mucosa ex vivo
    • Mariadason JM, Kilias D, Catto-Smith A & Gibson PR (1999) Effect of butyrate on paracellular permeability in rat distal colonic mucosa ex vivo. J Gastroenterol Hepatol 14, 873-879.
    • (1999) J Gastroenterol Hepatol , vol.14 , pp. 873-879
    • Mariadason, J.M.1    Kilias, D.2    Catto-Smith, A.3    Gibson, P.R.4
  • 32
    • 33746780618 scopus 로고    scopus 로고
    • Short-chain fatty acid formation in the hindgut of rats fed native and fermented oat fibre concentrates
    • Lambo-Fodje AM, Oste R & Nyman ME (2006) Short-chain fatty acid formation in the hindgut of rats fed native and fermented oat fibre concentrates. Br J Nutr 96, 47-55.
    • (2006) Br J Nutr , vol.96 , pp. 47-55
    • Lambo-Fodje, A.M.1    Oste, R.2    Nyman, M.E.3
  • 33
    • 0031898619 scopus 로고    scopus 로고
    • Nonionic diffusion of short-chain fatty acids across rat colon
    • Charney AN, Micic L & Egnor RW (1998) Nonionic diffusion of short-chain fatty acids across rat colon. Am J Physiol 274, G518-G524.
    • (1998) Am J Physiol , vol.274
    • Charney, A.N.1    Micic, L.2    Egnor, R.W.3
  • 34
    • 0026545041 scopus 로고
    • Involvement of cytoskeletal proteins in the barrier function of the human erythrocyte membrane. III. Permeability of spectrin-depleted inside-out membrane vesicles to hydrophilic nonelectrolytes. Formation of leaks by chemical or enzymatic modification of membrane proteins
    • Klonk S & Deuticke B (1992) Involvement of cytoskeletal proteins in the barrier function of the human erythrocyte membrane. III. Permeability of spectrin-depleted inside-out membrane vesicles to hydrophilic nonelectrolytes. Formation of leaks by chemical or enzymatic modification of membrane proteins. Biochim Riophys Acta 1106 143-150.
    • (1992) Biochim Riophys Acta , vol.1106 , pp. 143-150
    • Klonk, S.1    Deuticke, B.2
  • 35
    • 0038363378 scopus 로고    scopus 로고
    • The orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids
    • Brown AJ, Goldsworthy SM, Barnes AA, et al. (2003) The orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids. J Biol Chem 278, 11312-11319.
    • (2003) J Biol Chem , vol.278 , pp. 11312-11319
    • Brown, A.J.1    Goldsworthy, S.M.2    Barnes, A.A.3
  • 37
    • 33646376658 scopus 로고    scopus 로고
    • Short-chain fatty acid receptor, GPR43, is expressed by enteroendocrine ceffs and mucosal mast cells in rat intestine
    • Karaki S, Mitsui R, Hayashi H, Kato I, Sugiya H, Iwanaga T, Furness JB & Kuwahara A (2006) Short-chain fatty acid receptor, GPR43, is expressed by enteroendocrine ceffs and mucosal mast cells in rat intestine. Cell Tissue Res 324, 353-360.
    • (2006) Cell Tissue Res , vol.324 , pp. 353-360
    • Karaki, S.1    Mitsui, R.2    Hayashi, H.3    Kato, I.4    Sugiya, H.5    Iwanaga, T.6    Furness, J.B.7    Kuwahara, A.8
  • 38
    • 33845621932 scopus 로고    scopus 로고
    • Cooperative mitogenic signaling by G protein-coupled receptors and growth factors is dependent on G(q/11)
    • Kong KC, Billington CK, Gandhi U, Panettieri RA Jr & Penn RB (2006) Cooperative mitogenic signaling by G protein-coupled receptors and growth factors is dependent on G(q/11). FASEB J 20, 1558-1560.
    • (2006) FASEB J , vol.20 , pp. 1558-1560
    • Kong, K.C.1    Billington, C.K.2    Gandhi, U.3    Panettieri Jr, R.A.4    Penn, R.B.5
  • 39
    • 0030949124 scopus 로고    scopus 로고
    • Functional rafts in cell membranes
    • Simons K & Ikonen E (1997) Functional rafts in cell membranes. Nature 387, 569-572.
    • (1997) Nature , vol.387 , pp. 569-572
    • Simons, K.1    Ikonen, E.2
  • 40
    • 0034625373 scopus 로고    scopus 로고
    • Structure and function of sphingolipids-and cholesterol-rich membrane rafts
    • Brown DA & London E (2000) Structure and function of sphingolipids-and cholesterol-rich membrane rafts. J Biol Chem 275, 17221-17224.
    • (2000) J Biol Chem , vol.275 , pp. 17221-17224
    • Brown, D.A.1    London, E.2
  • 41
    • 0037201955 scopus 로고    scopus 로고
    • Dynamics of plasma membrane microdomains and cross-talk to the insulin signalling cascade
    • Muller G (2002) Dynamics of plasma membrane microdomains and cross-talk to the insulin signalling cascade. FEBS Lett 531, 81-87.
    • (2002) FEBS Lett , vol.531 , pp. 81-87
    • Muller, G.1


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