Screening and replication using the same data set: Testing strategies for family-based studies in which all probands are affected

PLoS Genetics

Volumn 4, Issue 9, 2008, Pages

  Murphy, Amy ^a,b   Weiss, Scott T ^a,b   Lange, Christoph ^a,b,c  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; ASTHMA; BONFERRONI CORRECTION; CALCULATION; CHILD; DATA ANALYSIS; EFFECT SIZE; FAMILY BASED ASSOCIATION TRANSMISSION DISEQUILIBRIUM TEST; FAMILY STUDY; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC MARKER; GENETIC SCREENING; GENOTYPE; HEREDITY; HUMAN; MAJOR CLINICAL STUDY; MATHEMATICAL ANALYSIS; METHODOLOGY; NUCLEOTIDE SEQUENCE; PARENT; PROGENY; SIMULATION; SINGLE NUCLEOTIDE POLYMORPHISM; BIOLOGICAL MODEL; COMPUTER SIMULATION; FAMILY; FEMALE; GENETICS; GENOME; MALE; MEDICAL GENETICS; PEDIGREE; POPULATION GENETICS; QUANTITATIVE TRAIT; STATISTICAL MODEL;

ASTHMA; CHILD; COMPUTER SIMULATION; FAMILY; FEMALE; GENETIC MARKERS; GENETIC SCREENING; GENETICS, MEDICAL; GENETICS, POPULATION; GENOME, HUMAN; HUMANS; MALE; MODELS, GENETIC; MODELS, STATISTICAL; PEDIGREE; POLYMORPHISM, SINGLE NUCLEOTIDE; QUANTITATIVE TRAIT, HERITABLE;

EID: 52949101735     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1000197     Document Type: Article

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