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Volumn 14, Issue 20, 2008, Pages 1936-1949

Therapeutic drug monitoring of busulfan in transplantation

Author keywords

Busulfan; Hematopoietic stem cell (HSCs); Intravenous (IV) Bu; Malignancies; Therapeutic drug monitoring (TDM)

Indexed keywords

ALKYLATING AGENT; BUSULFAN; CYCLOPHOSPHAMIDE; CYTOTOXIC AGENT; ETOPOSIDE; FLUDARABINE; LYMPHOCYTE ANTIBODY; MELPHALAN; METRONIDAZOLE; PHENYTOIN; PYRROLE DERIVATIVE; THIOTEPA;

EID: 52949100982     PISSN: 13816128     EISSN: None     Source Type: Journal    
DOI: 10.2174/138161208785061382     Document Type: Review
Times cited : (76)

References (162)
  • 2
    • 0033823462 scopus 로고    scopus 로고
    • Plasma concentration monitoring of busulfan: Does it improve clinical outcome?
    • McCune JS, Gibbs JP, Slattery JT. Plasma concentration monitoring of busulfan: Does it improve clinical outcome? Clin Pharmacokinet 2000; 39: 155-65.
    • (2000) Clin Pharmacokinet , vol.39 , pp. 155-165
    • McCune, J.S.1    Gibbs, J.P.2    Slattery, J.T.3
  • 3
    • 0027323727 scopus 로고
    • Busulfan disposition: The role of therapeutic monitoring in bone marrow transplantation induction regimens
    • Grochow LB. Busulfan disposition: The role of therapeutic monitoring in bone marrow transplantation induction regimens. Semin Oncol 1993; 20: 18-25.
    • (1993) Semin Oncol , vol.20 , pp. 18-25
    • Grochow, L.B.1
  • 4
    • 0028556958 scopus 로고
    • Pharmacologically-guided dose adjustment of busulfan in high-dose chemotherapy regimens: Rationale and pitfalls (review)
    • Vassal G. Pharmacologically-guided dose adjustment of busulfan in high-dose chemotherapy regimens: Rationale and pitfalls (review). Anticancer Res 1994; 14: 2363-70.
    • (1994) Anticancer Res , vol.14 , pp. 2363-2370
    • Vassal, G.1
  • 5
  • 6
    • 0033946560 scopus 로고    scopus 로고
    • Allogeneic stem cell transplantation (BMT) for AML and MDS following i.v. busulfan and cyclophosphamide (i.v. BuCy)
    • Andersson BS, GaJewski J, Donato M, Giralt S, Gian V, Wingard J, et al. Allogeneic stem cell transplantation (BMT) for AML and MDS following i.v. busulfan and cyclophosphamide (i.v. BuCy). Bone Marrow Transplant 2000; 25(Suppl 2): S35-8.
    • (2000) Bone Marrow Transplant , vol.25 , Issue.SUPPL. 2
    • Andersson, B.S.1    GaJewski, J.2    Donato, M.3    Giralt, S.4    Gian, V.5    Wingard, J.6
  • 7
    • 0034567061 scopus 로고    scopus 로고
    • Acute safety and pharmacokinetics of intravenous busulfan when used with oral busulfan and cyclophosphamide as pretransplantation conditioning therapy: A phase I study
    • Andersson BS, Madden T, Tran HT, Hu WW, Blume KG, Chow DS, et al. Acute safety and pharmacokinetics of intravenous busulfan when used with oral busulfan and cyclophosphamide as pretransplantation conditioning therapy: A phase I study. Biol Blood Marrow Transplant 2000; 6: 548-54.
    • (2000) Biol Blood Marrow Transplant , vol.6 , pp. 548-554
    • Andersson, B.S.1    Madden, T.2    Tran, H.T.3    Hu, W.W.4    Blume, K.G.5    Chow, D.S.6
  • 8
    • 0036205591 scopus 로고    scopus 로고
    • Conditioning therapy with intravenous busulfan and cyclophosphamide (IV BuCy2) for hematologic malignancies prior to allogeneic stem cell transplantation: A phase II study
    • Andersson BS, Kashyap A, Gian V, Wingard JR, Fernandez H, Cagnoni PJ, et al. Conditioning therapy with intravenous busulfan and cyclophosphamide (IV BuCy2) for hematologic malignancies prior to allogeneic stem cell transplantation: A phase II study. Biol Blood Marrow Transplant 2002; 8: 145-54.
    • (2002) Biol Blood Marrow Transplant , vol.8 , pp. 145-154
    • Andersson, B.S.1    Kashyap, A.2    Gian, V.3    Wingard, J.R.4    Fernandez, H.5    Cagnoni, P.J.6
  • 9
    • 0036398471 scopus 로고    scopus 로고
    • Busulfan systemic exposure relative to regimen-related toxicity and acute graft-versus-host disease: Defining a therapeutic window for i.v. BuCy2 in chronic myelogenous leukemia
    • Andersson BS, Thall PF, Madden T, Couriel D, Wang X, Tran HT, et al. Busulfan systemic exposure relative to regimen-related toxicity and acute graft-versus-host disease: Defining a therapeutic window for i.v. BuCy2 in chronic myelogenous leukemia. Biol Blood Marrow Transplant 2002; 8: 477-85.
    • (2002) Biol Blood Marrow Transplant , vol.8 , pp. 477-485
    • Andersson, B.S.1    Thall, P.F.2    Madden, T.3    Couriel, D.4    Wang, X.5    Tran, H.T.6
  • 11
    • 0036402048 scopus 로고    scopus 로고
    • Evaluation of safety and pharmacokinetics of administering intravenous busulfan in a twice-daily or daily schedule to patients with advanced hematologic malignant disease undergoing stem cell transplantation
    • Fernandez HF, Tran HT, Albrecht F, Lennon S, Caldera H, Goodman MS. Evaluation of safety and pharmacokinetics of administering intravenous busulfan in a twice-daily or daily schedule to patients with advanced hematologic malignant disease undergoing stem cell transplantation. Biol Blood Marrow Tranplant 2002; 8: 486-92.
    • (2002) Biol Blood Marrow Tranplant , vol.8 , pp. 486-492
    • Fernandez, H.F.1    Tran, H.T.2    Albrecht, F.3    Lennon, S.4    Caldera, H.5    Goodman, M.S.6
  • 12
    • 0036400369 scopus 로고    scopus 로고
    • Intravenous versus oral busulfan as part of a busulfan/cyclophosphamide preparative regimen for allogeneic hematopoietic stem cell transplantation: Decreased incidence of hepatic venoocclusive disease (HVOD), HVOD-related mortality, and overall 100-day mortality
    • Kashyap A, Wingard J, Cagnoni P, Roy J, Tarantolo S, Hu W, et al. Intravenous versus oral busulfan as part of a busulfan/cyclophosphamide preparative regimen for allogeneic hematopoietic stem cell transplantation: Decreased incidence of hepatic venoocclusive disease (HVOD), HVOD-related mortality, and overall 100-day mortality. Biol Blood, Marrow Transplant 2002; 8: 493-500.
    • (2002) Biol Blood, Marrow Transplant , vol.8 , pp. 493-500
    • Kashyap, A.1    Wingard, J.2    Cagnoni, P.3    Roy, J.4    Tarantolo, S.5    Hu, W.6
  • 13
    • 0036401558 scopus 로고    scopus 로고
    • Once-daily intravenous busulfan given with fludarabine as conditioning for allogeneic stem cell transplantation: Study of pharmacokinetics and early clinical outcomes
    • Russell JA, Tran HT, Quinlan D, Chaudhry A, Duggan P, Brown C, et al. Once-daily intravenous busulfan given with fludarabine as conditioning for allogeneic stem cell transplantation: Study of pharmacokinetics and early clinical outcomes. Biol Blood Marrow Transplant 2002; 8: 468-76.
    • (2002) Biol Blood Marrow Transplant , vol.8 , pp. 468-476
    • Russell, J.A.1    Tran, H.T.2    Quinlan, D.3    Chaudhry, A.4    Duggan, P.5    Brown, C.6
  • 15
    • 0742323838 scopus 로고    scopus 로고
    • Intravenous busulfan in pretransplant chemotherapy: Bioavailability and patient benefit Biol Blood Marrow
    • Andesson BS, Kashyap A, Couriel D, Madden T, de Lima M, Thall PF, et al. Intravenous busulfan in pretransplant chemotherapy: bioavailability and patient benefit Biol Blood Marrow Transplant 2003; 9: 722-4.
    • (2003) Transplant , vol.9 , pp. 722-724
    • Andesson, B.S.1    Kashyap, A.2    Couriel, D.3    Madden, T.4    de Lima, M.5    Thall, P.F.6
  • 16
    • 0037562931 scopus 로고    scopus 로고
    • Intravenous busulfan-based conditioning prior to allogeneic hematopoietic stem cell transplantation: Myeloablation with reduced toxicity
    • Shimoni A, Bielorai B, Toren A, Hardan I, Avigdor A, Yeshurun M, et al. Intravenous busulfan-based conditioning prior to allogeneic hematopoietic stem cell transplantation: Myeloablation with reduced toxicity. Exp Hematol 2003; 31: 428-34.
    • (2003) Exp Hematol , vol.31 , pp. 428-434
    • Shimoni, A.1    Bielorai, B.2    Toren, A.3    Hardan, I.4    Avigdor, A.5    Yeshurun, M.6
  • 17
    • 0742300045 scopus 로고    scopus 로고
    • Slattery JT. Re: Intravenous versus oral busulfan - perhaps not as different as suggested. Biol Blood Marrow Transplant 2003; 9: 282-4
    • Slattery JT. Re: Intravenous versus oral busulfan - perhaps not as different as suggested. Biol Blood Marrow Transplant 2003; 9: 282-4
  • 18
    • 3242810563 scopus 로고    scopus 로고
    • Once-daily intravenous busulfan and fludarabine: Clinical and pharmacokinetic results of a myeloablative, reduced-toxicity conditioning regimen for allogeneic stem cell transplantation in AML and MDS
    • de Lima M, Couriel D, Thall PF, Wang X, Madden T, Jones R, et al. Once-daily intravenous busulfan and fludarabine: Clinical and pharmacokinetic results of a myeloablative, reduced-toxicity conditioning regimen for allogeneic stem cell transplantation in AML and MDS. Blood 2004; 104: 857-64.
    • (2004) Blood , vol.104 , pp. 857-864
    • de Lima, M.1    Couriel, D.2    Thall, P.F.3    Wang, X.4    Madden, T.5    Jones, R.6
  • 19
    • 2942530481 scopus 로고    scopus 로고
    • Nguyen L, Fuller D, Lennon S, Leger F, Puozzo C. I.V. busulfan in pediatrics: A novel dosing to improve safety/efficacy for hematopoietic progenitor cell transplantation recipients. Bone Marrow Transplant 2004; 33: 979-87.
    • Nguyen L, Fuller D, Lennon S, Leger F, Puozzo C. I.V. busulfan in pediatrics: A novel dosing to improve safety/efficacy for hematopoietic progenitor cell transplantation recipients. Bone Marrow Transplant 2004; 33: 979-87.
  • 20
    • 3242709629 scopus 로고    scopus 로고
    • Comparison of 100-day mortality rates associated with i.v. busulfan and cyclophosphamide vs other preparative regimens in allogeneic bone marrow transplantation for chronic myelogenous leukemia: Bayesian sensitivity analyses of confounded treatment and center effects
    • Thall PF, Champlin RE, Andersson BS. Comparison of 100-day mortality rates associated with i.v. busulfan and cyclophosphamide vs other preparative regimens in allogeneic bone marrow transplantation for chronic myelogenous leukemia: Bayesian sensitivity analyses of confounded treatment and center effects. Bone Marrow Transplant 2004; 33: 1191-9.
    • (2004) Bone Marrow Transplant , vol.33 , pp. 1191-1199
    • Thall, P.F.1    Champlin, R.E.2    Andersson, B.S.3
  • 21
    • 6444243739 scopus 로고    scopus 로고
    • Pharmacokinetics and individualized dose adjustment of intravenous busulfan in children with advanced hematologic malignancies undergoing allogeneic stem cell transplantation
    • Tran H, Petropoulos D, Worth L, Mullen CA, Madden T, Andersson B, et al. Pharmacokinetics and individualized dose adjustment of intravenous busulfan in children with advanced hematologic malignancies undergoing allogeneic stem cell transplantation. Biol Blood Marrow Transplant 2004; 10: 805-12.
    • (2004) Biol Blood Marrow Transplant , vol.10 , pp. 805-812
    • Tran, H.1    Petropoulos, D.2    Worth, L.3    Mullen, C.A.4    Madden, T.5    Andersson, B.6
  • 22
    • 4444242994 scopus 로고    scopus 로고
    • Dose modification protocol using intravenous busulfan (Busulfex) and cyclophosphamide followed by autologous or allogeneic peripheral blood stem cell transplantation in patients with hematologic malignancies
    • Williams CB, Day SD, Reed MD, Copelan EA, Bechtel T, Leather HL, et al. Dose modification protocol using intravenous busulfan (Busulfex) and cyclophosphamide followed by autologous or allogeneic peripheral blood stem cell transplantation in patients with hematologic malignancies. Biol Blood Marrow Transplant 2004; 10: 614-23.
    • (2004) Biol Blood Marrow Transplant , vol.10 , pp. 614-623
    • Williams, C.B.1    Day, S.D.2    Reed, M.D.3    Copelan, E.A.4    Bechtel, T.5    Leather, H.L.6
  • 23
    • 16244403369 scopus 로고    scopus 로고
    • Targeting once-daily intravenous busulfan in combination with fludarabine before allogeneic hematopoietic cell transplantation
    • Jenke A, Freiberg-Richter J, Johne C, Knoth H, Schleyer E, Ehninger G, et al. Targeting once-daily intravenous busulfan in combination with fludarabine before allogeneic hematopoietic cell transplantation. Bone Marrow Transplant 2005; 35: 627-8.
    • (2005) Bone Marrow Transplant , vol.35 , pp. 627-628
    • Jenke, A.1    Freiberg-Richter, J.2    Johne, C.3    Knoth, H.4    Schleyer, E.5    Ehninger, G.6
  • 24
    • 14344255918 scopus 로고    scopus 로고
    • Morbidity and nonrelapse mortality after allogeneic bone marrow transplantation in adult leukemia patients conditioned with busulfan plus cyclophosphamide: A retrospective comparison of oral versus intravenous busulfan
    • Kim SE, Lee JH, Choi SJ, Ryu SG, Lee KH. Morbidity and nonrelapse mortality after allogeneic bone marrow transplantation in adult leukemia patients conditioned with busulfan plus cyclophosphamide: A retrospective comparison of oral versus intravenous busulfan. Haematologica 2005; 90: 285-6.
    • (2005) Haematologica , vol.90 , pp. 285-286
    • Kim, S.E.1    Lee, J.H.2    Choi, S.J.3    Ryu, S.G.4    Lee, K.H.5
  • 25
    • 23244433213 scopus 로고    scopus 로고
    • Decreased incidence of hepatic veno-occlusive disease and fewer hemostatic derangements associated with intravenous busulfan vs oral busulfan in adults conditioned with busulfan + cyclophosphamide for allogeneic bone marrow transplantation
    • Lee JH, Choi SJ, Kim SE, Park CJ, Chi HS, Lee MS, et al. Decreased incidence of hepatic veno-occlusive disease and fewer hemostatic derangements associated with intravenous busulfan vs oral busulfan in adults conditioned with busulfan + cyclophosphamide for allogeneic bone marrow transplantation. Ann Hematol 2005; 84: 321-30.
    • (2005) Ann Hematol , vol.84 , pp. 321-330
    • Lee, J.H.1    Choi, S.J.2    Kim, S.E.3    Park, C.J.4    Chi, H.S.5    Lee, M.S.6
  • 27
    • 11844259396 scopus 로고    scopus 로고
    • Intravenous busulfan in children prior to stem cell transplantation: Study of pharmacokinetics in association with early clinical outcome and toxicity
    • Zwaveling J, Bredius RG, Cremers SC, Ball LM, Lankester AC, Teepe-Twiss IM, et al. Intravenous busulfan in children prior to stem cell transplantation: Study of pharmacokinetics in association with early clinical outcome and toxicity. Bone Marrow Transplant 2005; 35: 17-23
    • (2005) Bone Marrow Transplant , vol.35 , pp. 17-23
    • Zwaveling, J.1    Bredius, R.G.2    Cremers, S.C.3    Ball, L.M.4    Lankester, A.C.5    Teepe-Twiss, I.M.6
  • 28
    • 33745159360 scopus 로고    scopus 로고
    • Improved outcomes in intermediate- and high-risk aggressive non-Hodgkin lymphoma after autologous hematopoietic stem cell transplantation substituting intravenous for oral busulfan in a busulfan, cyclophosphamide, and etoposide preparative regimen
    • Aggarwal C, Gupta S, Vaughan WP, Saylors GB, Salzman DE, Katz RO, et al. Improved outcomes in intermediate- and high-risk aggressive non-Hodgkin lymphoma after autologous hematopoietic stem cell transplantation substituting intravenous for oral busulfan in a busulfan, cyclophosphamide, and etoposide preparative regimen. Biol Blood Marrow Transplant 2006; 12: 770-7.
    • (2006) Biol Blood Marrow Transplant , vol.12 , pp. 770-777
    • Aggarwal, C.1    Gupta, S.2    Vaughan, W.P.3    Saylors, G.B.4    Salzman, D.E.5    Katz, R.O.6
  • 29
    • 33646837336 scopus 로고    scopus 로고
    • Pretransplant conditioning in adults and children: Dose assurance with intravenous busulfan
    • Fisher VL, Barnes YJ, Nuss SL. Pretransplant conditioning in adults and children: Dose assurance with intravenous busulfan. Oncol Nurs Forum 2006; 33: E36-43.
    • (2006) Oncol Nurs Forum , vol.33
    • Fisher, V.L.1    Barnes, Y.J.2    Nuss, S.L.3
  • 30
    • 33644909940 scopus 로고    scopus 로고
    • Pharmacokinetics of a test dose of intravenous busulfan guide dose modifications to achieve an optimal area under the curve of a single daily dose of intravenous busulfan in children undergoing a reduced-intensity conditioning regimen with hematopoietic stem cell transplantation
    • Kletzel M, Jacobsohn D, Duerst R. Pharmacokinetics of a test dose of intravenous busulfan guide dose modifications to achieve an optimal area under the curve of a single daily dose of intravenous busulfan in children undergoing a reduced-intensity conditioning regimen with hematopoietic stem cell transplantation. Biol Blood Marrow Transplant 2006; 12: 472-9.
    • (2006) Biol Blood Marrow Transplant , vol.12 , pp. 472-479
    • Kletzel, M.1    Jacobsohn, D.2    Duerst, R.3
  • 31
    • 28844489966 scopus 로고    scopus 로고
    • Intravenous busulfan in adults prior to haematopoietic stem cell transplantation: A population pharmacokinetic study
    • Nguyen L, Leger F, Lennon S, Puozzo C. Intravenous busulfan in adults prior to haematopoietic stem cell transplantation: A population pharmacokinetic study. Cancer Chemother Pharmacol 2006; 57: 191-8.
    • (2006) Cancer Chemother Pharmacol , vol.57 , pp. 191-198
    • Nguyen, L.1    Leger, F.2    Lennon, S.3    Puozzo, C.4
  • 32
    • 33745661009 scopus 로고    scopus 로고
    • Monitoring of N,N-dimethyl-acetamide in children during i.v.-busulfan therapy by liquid chromatography-mass spectrometry
    • Oechtering D, Boos J, Hempel G. Monitoring of N,N-dimethyl-acetamide in children during i.v.-busulfan therapy by liquid chromatography-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 2006; 838: 129-34.
    • (2006) J Chromatogr B Analyt Technol Biomed Life Sci , vol.838 , pp. 129-134
    • Oechtering, D.1    Boos, J.2    Hempel, G.3
  • 33
    • 32844470773 scopus 로고    scopus 로고
    • Population pharmacokinetics of intravenous busulfan in patients undergoing hematopoietic stem cell transplantation
    • Takama H, Tanaka H, Nakashima D, Ueda R, Takaue Y. Population pharmacokinetics of intravenous busulfan in patients undergoing hematopoietic stem cell transplantation. Bone Marrow Transplant 2006; 37: 345-51.
    • (2006) Bone Marrow Transplant , vol.37 , pp. 345-351
    • Takama, H.1    Tanaka, H.2    Nakashima, D.3    Ueda, R.4    Takaue, Y.5
  • 34
    • 33748992558 scopus 로고    scopus 로고
    • Once-daily intravenous busulfan in children prior to stem cell transplantation: Study of pharmacokinetics and early clinical outcomes
    • Zwaveling J, den Hartigh J, Lankester AC, Guchelaar HJ, Egeler RM, Bredius RG. Once-daily intravenous busulfan in children prior to stem cell transplantation: Study of pharmacokinetics and early clinical outcomes. Anticancer Drugs 2006; 17: 1099-105.
    • (2006) Anticancer Drugs , vol.17 , pp. 1099-1105
    • Zwaveling, J.1    den Hartigh, J.2    Lankester, A.C.3    Guchelaar, H.J.4    Egeler, R.M.5    Bredius, R.G.6
  • 35
    • 33845753369 scopus 로고    scopus 로고
    • Population pharmacokinetic-based dosing of intravenous busulfan in pediatric patients
    • Booth BP, Rahman A, Dagher R, Griebel D, Lennon S, Fuller D, et al. Population pharmacokinetic-based dosing of intravenous busulfan in pediatric patients. J Clin Pharmacol 2007; 47: 101-11.
    • (2007) J Clin Pharmacol , vol.47 , pp. 101-111
    • Booth, B.P.1    Rahman, A.2    Dagher, R.3    Griebel, D.4    Lennon, S.5    Fuller, D.6
  • 36
    • 34248214199 scopus 로고    scopus 로고
    • Pharmacokinetics and tolerability of intravenous busulfan in hematopoietic stem cell transplantation
    • Cho YH, Lim HA, Lee MH, Kim I, Lee JS, Park S, et al. Pharmacokinetics and tolerability of intravenous busulfan in hematopoietic stem cell transplantation. Clin Transplant 2007; 21: 417-22.
    • (2007) Clin Transplant , vol.21 , pp. 417-422
    • Cho, Y.H.1    Lim, H.A.2    Lee, M.H.3    Kim, I.4    Lee, J.S.5    Park, S.6
  • 37
    • 34548089422 scopus 로고    scopus 로고
    • Intravenous busulfan: In the conditioning treatment of pediatric patients prior to hematopoietic stem cell transplantation
    • Hoy SM, Lyseng-Williamson KA. Intravenous busulfan: In the conditioning treatment of pediatric patients prior to hematopoietic stem cell transplantation. Paediatr Drugs 2007; 9: 271-8.
    • (2007) Paediatr Drugs , vol.9 , pp. 271-278
    • Hoy, S.M.1    Lyseng-Williamson, K.A.2
  • 38
    • 33845984552 scopus 로고    scopus 로고
    • Pharmacokinetics of once-daily IV busulfan as part of pretransplantation preparative regimens: A comparison with an every 6-hour dosing schedule
    • Madden T, de Lima M, Thapar N, Nguyen J, Roberson S, Couriel D, et al. Pharmacokinetics of once-daily IV busulfan as part of pretransplantation preparative regimens: A comparison with an every 6-hour dosing schedule. Biol Blood Marrow Transplant 2007; 13: 56-64
    • (2007) Biol Blood Marrow Transplant , vol.13 , pp. 56-64
    • Madden, T.1    de Lima, M.2    Thapar, N.3    Nguyen, J.4    Roberson, S.5    Couriel, D.6
  • 39
    • 34250173083 scopus 로고    scopus 로고
    • Allogeneic transplantation for adult acute leukemia in first and second remission with a novel regimen incorporating daily intravenous busulfan, fludarabine, 400 CGY total-body irradiation, and thymoglobulin
    • Russell JA, Savoie ML, Balogh A, Turner AR, Larratt L, Chaudhry MA, et al. Allogeneic transplantation for adult acute leukemia in first and second remission with a novel regimen incorporating daily intravenous busulfan, fludarabine, 400 CGY total-body irradiation, and thymoglobulin. Biol Blood Marrow Transplant 2007; 13: 814-21.
    • (2007) Biol Blood Marrow Transplant , vol.13 , pp. 814-821
    • Russell, J.A.1    Savoie, M.L.2    Balogh, A.3    Turner, A.R.4    Larratt, L.5    Chaudhry, M.A.6
  • 40
    • 34547683653 scopus 로고    scopus 로고
    • Randomized comparison of four-times-daily versus once-daily intravenous busulfan in conditioning therapy for hematopoietic cell transplantation
    • Ryu SG, Lee JH, Choi SJ, Lee YS, Seol M, Hur EH, et al. Randomized comparison of four-times-daily versus once-daily intravenous busulfan in conditioning therapy for hematopoietic cell transplantation. Biol Blood Marrow Transplant 2007; 13: 1095-105.
    • (2007) Biol Blood Marrow Transplant , vol.13 , pp. 1095-1105
    • Ryu, S.G.1    Lee, J.H.2    Choi, S.J.3    Lee, Y.S.4    Seol, M.5    Hur, E.H.6
  • 41
    • 33847079603 scopus 로고    scopus 로고
    • Pharmacokinetic disposition and clinical outcomes in infants and children receiving intravenous busulfan for allogeneic hematopoietic stem cell transplantation
    • Schechter T, Finkelstein Y, Doyle J, Verjee Z, Moretti M, Koren G, et al. Pharmacokinetic disposition and clinical outcomes in infants and children receiving intravenous busulfan for allogeneic hematopoietic stem cell transplantation. Biol Blood Marrow Transplant 2007; 13: 307-14.
    • (2007) Biol Blood Marrow Transplant , vol.13 , pp. 307-314
    • Schechter, T.1    Finkelstein, Y.2    Doyle, J.3    Verjee, Z.4    Moretti, M.5    Koren, G.6
  • 42
    • 34848829531 scopus 로고    scopus 로고
    • Prospective validation of a novel IV busulfan fixed dosing for paediatric patients to improve therapeutic AUC targeting without drug monitoring
    • Vassal G, Michel G, Esperou H, Gentet JC, Valteau-Couanet D, Doz F, et al. Prospective validation of a novel IV busulfan fixed dosing for paediatric patients to improve therapeutic AUC targeting without drug monitoring. Cancer Chemother Pharmacol 2008; 61: 113-23.
    • (2008) Cancer Chemother Pharmacol , vol.61 , pp. 113-123
    • Vassal, G.1    Michel, G.2    Esperou, H.3    Gentet, J.C.4    Valteau-Couanet, D.5    Doz, F.6
  • 43
    • 35748979989 scopus 로고    scopus 로고
    • Risk factors and mortality predictors of hepatic veno-occlusive disease after pediatric hematopoietic stem cell transplantation
    • Cheuk DK, Wang P, Lee TL, Chiang AK, Ha SY, Lau YL, et al. Risk factors and mortality predictors of hepatic veno-occlusive disease after pediatric hematopoietic stem cell transplantation. Bone Marrow Transplant 2007; 40: 935-44.
    • (2007) Bone Marrow Transplant , vol.40 , pp. 935-944
    • Cheuk, D.K.1    Wang, P.2    Lee, T.L.3    Chiang, A.K.4    Ha, S.Y.5    Lau, Y.L.6
  • 44
    • 38149015428 scopus 로고    scopus 로고
    • High busulfan exposure is associated with worse outcomes in a daily i.v. busulfan and fludarabine allogeneic transplant regimen
    • Geddes M, Kangarloo SB, Naveed F, Quinlan D, Chaudhry MA, Stewart D, et al. High busulfan exposure is associated with worse outcomes in a daily i.v. busulfan and fludarabine allogeneic transplant regimen. Biol Blood Marrow Transplant 2008; 14: 220-8.
    • (2008) Biol Blood Marrow Transplant , vol.14 , pp. 220-228
    • Geddes, M.1    Kangarloo, S.B.2    Naveed, F.3    Quinlan, D.4    Chaudhry, M.A.5    Stewart, D.6
  • 45
    • 33847046703 scopus 로고    scopus 로고
    • Adult recipients of matched related donor blood cell transplants given myeloablative regimens including pretransplant antithymocyte globulin have lower mortality related to graft-versus-host disease: A matched pair analysis
    • Russell JA, Turner AR, Larratt L, Chaudhry A, Morris D, Brown C, et al. Adult recipients of matched related donor blood cell transplants given myeloablative regimens including pretransplant antithymocyte globulin have lower mortality related to graft-versus-host disease: A matched pair analysis. Biol Blood Marrow Transplant 2007; 13: 299-306.
    • (2007) Biol Blood Marrow Transplant , vol.13 , pp. 299-306
    • Russell, J.A.1    Turner, A.R.2    Larratt, L.3    Chaudhry, A.4    Morris, D.5    Brown, C.6
  • 46
    • 32144433537 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic study of once-daily dosing of intravenously administered busulfan in the setting of a reduced-intensity preparative regimen and allogeneic hematopoietic stem cell transplantation as immunotherapy for renal cell carcinoma
    • Shaughnessy P, Alexander W, Tran H, Ririe D, Splichal J, Pollack M, et al. Phase I and pharmacokinetic study of once-daily dosing of intravenously administered busulfan in the setting of a reduced-intensity preparative regimen and allogeneic hematopoietic stem cell transplantation as immunotherapy for renal cell carcinoma. Mil Med 2006; 171: 161-5.
    • (2006) Mil Med , vol.171 , pp. 161-165
    • Shaughnessy, P.1    Alexander, W.2    Tran, H.3    Ririe, D.4    Splichal, J.5    Pollack, M.6
  • 47
    • 31444444950 scopus 로고    scopus 로고
    • Allogeneic hematopoietic stem-cell transplantation in AML and MDS using myeloablative versus reduced-intensity conditioning: The role of dose intensity
    • Shimoni A, Hardan I, Shem-Tov N, Yeshurun M, Yerushalmi R, Avigdor A, et al. Allogeneic hematopoietic stem-cell transplantation in AML and MDS using myeloablative versus reduced-intensity conditioning: The role of dose intensity. Leukemia 2006; 20: 322-8.
    • (2006) Leukemia , vol.20 , pp. 322-328
    • Shimoni, A.1    Hardan, I.2    Shem-Tov, N.3    Yeshurun, M.4    Yerushalmi, R.5    Avigdor, A.6
  • 48
    • 18144427165 scopus 로고    scopus 로고
    • Modification of the Bu/Cy myeloablative regimen using daily parenteral busulfan: Reduced toxicity without the need for pharmacokinetic monitoring
    • Mamlouk K, Saracino G, Berryman RB, Fay JW, Pineiro LA, Vance EA, et al. Modification of the Bu/Cy myeloablative regimen using daily parenteral busulfan: Reduced toxicity without the need for pharmacokinetic monitoring. Bone Marrow Transplant 2005; 35: 747-54
    • (2005) Bone Marrow Transplant , vol.35 , pp. 747-754
    • Mamlouk, K.1    Saracino, G.2    Berryman, R.B.3    Fay, J.W.4    Pineiro, L.A.5    Vance, E.A.6
  • 49
    • 37349060017 scopus 로고    scopus 로고
    • Once-daily intravenous busulfan with therapeutic drug monitoring compared to conventional oral busulfan improves survival and engraftment in children undergoing allogeneic stem cell transplantation
    • Bartelink IH, Bredius RG, Ververs TT, Raphael MF, van Kesteren C, Bierings M, et al. Once-daily intravenous busulfan with therapeutic drug monitoring compared to conventional oral busulfan improves survival and engraftment in children undergoing allogeneic stem cell transplantation. Biol Blood Marrow Transplant 2008; 14: 88-98.
    • (2008) Biol Blood Marrow Transplant , vol.14 , pp. 88-98
    • Bartelink, I.H.1    Bredius, R.G.2    Ververs, T.T.3    Raphael, M.F.4    van Kesteren, C.5    Bierings, M.6
  • 51
    • 33748157848 scopus 로고    scopus 로고
    • Optimization of conditioning for marrow transplantation from unrelated donors for patients with aplastic anemia after failure of immunosuppressive therapy
    • Deeg HJ, O'Donnell M, Tolar J, Agarwal R, Harris RE, Feig SA, et al. Optimization of conditioning for marrow transplantation from unrelated donors for patients with aplastic anemia after failure of immunosuppressive therapy. Blood 2006; 108: 1485-91.
    • (2006) Blood , vol.108 , pp. 1485-1491
    • Deeg, H.J.1    O'Donnell, M.2    Tolar, J.3    Agarwal, R.4    Harris, R.E.5    Feig, S.A.6
  • 52
    • 0022946339 scopus 로고
    • Engraftment rates related to busulphan and cyclophosphamide dosages for displacement bone marrow transplants in fifty children
    • Hobbs JR, Hugh-Jones K, Shaw PJ, Downie CJ, Williamson S. Engraftment rates related to busulphan and cyclophosphamide dosages for displacement bone marrow transplants in fifty children. Bone Marrow Transplant 1986; 1: 201-8.
    • (1986) Bone Marrow Transplant , vol.1 , pp. 201-208
    • Hobbs, J.R.1    Hugh-Jones, K.2    Shaw, P.J.3    Downie, C.J.4    Williamson, S.5
  • 53
    • 4344564516 scopus 로고    scopus 로고
    • Nonmyeloablative allogeneic stem cell transplantation (NST) after truly nonmyeloablative and reduced intensity conditioning regimens
    • Banna GL, Aversa S, Sileni VC, Favaretto A, Ghiotto C, Monfardini S. Nonmyeloablative allogeneic stem cell transplantation (NST) after truly nonmyeloablative and reduced intensity conditioning regimens. Crit Rev Oncol Hematol 2004; 51: 171-89.
    • (2004) Crit Rev Oncol Hematol , vol.51 , pp. 171-189
    • Banna, G.L.1    Aversa, S.2    Sileni, V.C.3    Favaretto, A.4    Ghiotto, C.5    Monfardini, S.6
  • 54
    • 0022952392 scopus 로고
    • Busulphan and cyclophosphamide cause little early toxicity during displacement bone marrow transplantation in fifty children
    • Shaw PJ, Hugh-Jones K, Hobbs JR, Downie CJ, Barnes R. Busulphan and cyclophosphamide cause little early toxicity during displacement bone marrow transplantation in fifty children. Bone Marrow Transplant 1986; 1: 193-200.
    • (1986) Bone Marrow Transplant , vol.1 , pp. 193-200
    • Shaw, P.J.1    Hugh-Jones, K.2    Hobbs, J.R.3    Downie, C.J.4    Barnes, R.5
  • 56
    • 0023574955 scopus 로고
    • Bone marrow transplantation for leukemia following a new busulfan and cyclophosphamide regimen
    • Tutschka PJ, Copelan EA, Klein JP. Bone marrow transplantation for leukemia following a new busulfan and cyclophosphamide regimen. Blood 1987; 70: 1382-88.
    • (1987) Blood , vol.70 , pp. 1382-1388
    • Tutschka, P.J.1    Copelan, E.A.2    Klein, J.P.3
  • 57
    • 0027160828 scopus 로고
    • Busulfan and cyclophosphamide versus cyclophosphamide and total body irradiation for marrow transplantation in chronic myelogenous leukemia-a review
    • Santos GW. Busulfan and cyclophosphamide versus cyclophosphamide and total body irradiation for marrow transplantation in chronic myelogenous leukemia-a review. Leuk Lymphoma 1993; 11 Suppl 1: 201-4.
    • (1993) Leuk Lymphoma , vol.11 , Issue.SUPPL. 1 , pp. 201-204
    • Santos, G.W.1
  • 58
    • 0024533447 scopus 로고
    • Replacing total body irradiation with busulfan as conditioning of patients with leukemia for allogeneic marrow transplantation
    • Tutschka PJ, Copelan EA, Kapoor N. Replacing total body irradiation with busulfan as conditioning of patients with leukemia for allogeneic marrow transplantation. Transplant Proc 1989; 21: 2952-4.
    • (1989) Transplant Proc , vol.21 , pp. 2952-2954
    • Tutschka, P.J.1    Copelan, E.A.2    Kapoor, N.3
  • 59
    • 0026602075 scopus 로고
    • Radiation-free preparation for allogeneic bone marrow transplantation in adults with acute lymphoblastic leukemia
    • Copelan EA, Biggs JC, Avalos BR, Szer J, Cunningham I, Klein JP, et al. Radiation-free preparation for allogeneic bone marrow transplantation in adults with acute lymphoblastic leukemia. J Clin Oncol 1992; 10: 237-42.
    • (1992) J Clin Oncol , vol.10 , pp. 237-242
    • Copelan, E.A.1    Biggs, J.C.2    Avalos, B.R.3    Szer, J.4    Cunningham, I.5    Klein, J.P.6
  • 60
    • 0026644798 scopus 로고
    • Conditioning for allogeneic marrow transplantation in patients with lymphohematopoietic malignancies without the use of total body irradiation
    • Copelan EA, Deeg HJ. Conditioning for allogeneic marrow transplantation in patients with lymphohematopoietic malignancies without the use of total body irradiation. Blood 1992; 80: 1648-58.
    • (1992) Blood , vol.80 , pp. 1648-1658
    • Copelan, E.A.1    Deeg, H.J.2
  • 61
    • 0021035301 scopus 로고
    • Marrow transplantation for acute nonlymphocytic leukemia after treatment with busulfan and cyclophosphamide. N
    • Santos GW, Tutschka PJ, Brookmeyer R, Saral R, Beschorner WE, Bias WB, et al. Marrow transplantation for acute nonlymphocytic leukemia after treatment with busulfan and cyclophosphamide. N Engl J Med 1983; 309: 1347-53.
    • (1983) Engl J Med , vol.309 , pp. 1347-1353
    • Santos, G.W.1    Tutschka, P.J.2    Brookmeyer, R.3    Saral, R.4    Beschorner, W.E.5    Bias, W.B.6
  • 62
    • 2042454565 scopus 로고    scopus 로고
    • Conditioning with fludarabine and targeted busulfan for transplantation of allogeneic hematopoietic stem cells
    • Bornhauser M, Storer B, Slattery JT, Appelbaum FR, Deeg HJ, Hansen J, et al. Conditioning with fludarabine and targeted busulfan for transplantation of allogeneic hematopoietic stem cells. Blood 2003; 102: 820-6.
    • (2003) Blood , vol.102 , pp. 820-826
    • Bornhauser, M.1    Storer, B.2    Slattery, J.T.3    Appelbaum, F.R.4    Deeg, H.J.5    Hansen, J.6
  • 63
    • 0034625609 scopus 로고    scopus 로고
    • Rapid and sensitive high-performance liquid chromatographic method for busulfan assay in plasma
    • Bleyzac N, Barou P, Aulagner G. Rapid and sensitive high-performance liquid chromatographic method for busulfan assay in plasma. J Chromatogr B Biomed Sci Appl 2000; 742: 427-32.
    • (2000) J Chromatogr B Biomed Sci Appl , vol.742 , pp. 427-432
    • Bleyzac, N.1    Barou, P.2    Aulagner, G.3
  • 64
    • 0023901651 scopus 로고
    • Determination of busulfan in human plasma by gas chromatography with electron-capture detection
    • Chen TL, Grochow LB, Hurowitz LA, Brundrett RB. Determination of busulfan in human plasma by gas chromatography with electron-capture detection. J Chromatogr 1988; 425: 303-9.
    • (1988) J Chromatogr , vol.425 , pp. 303-309
    • Chen, T.L.1    Grochow, L.B.2    Hurowitz, L.A.3    Brundrett, R.B.4
  • 65
    • 20644455941 scopus 로고    scopus 로고
    • Development of a rapid and specific assay for detection of busulfan in human plasma by high-performance liquid chromatography/electrospray ionization tandem mass spectrometry
    • dos Reis EO, Vianna-Jorge R, Suarez-Kurtz G, Lima EL, Azevedo DA. Development of a rapid and specific assay for detection of busulfan in human plasma by high-performance liquid chromatography/electrospray ionization tandem mass spectrometry. Rapid Commun Mass Spectrom 2005; 19: 1666-74.
    • (2005) Rapid Commun Mass Spectrom , vol.19 , pp. 1666-1674
    • dos Reis, E.O.1    Vianna-Jorge, R.2    Suarez-Kurtz, G.3    Lima, E.L.4    Azevedo, D.A.5
  • 66
    • 0020578245 scopus 로고
    • Determination of busulfan in plasma by GCMS with selected-ion monitoring
    • Ehrsson H, Hassan M. Determination of busulfan in plasma by GCMS with selected-ion monitoring. J Pharm Sci 1983; 72: 1203-5.
    • (1983) J Pharm Sci , vol.72 , pp. 1203-1205
    • Ehrsson, H.1    Hassan, M.2
  • 68
    • 0034072688 scopus 로고    scopus 로고
    • High-performance liquid chromatographic quantification of busulfan in human serum after fluorescence derivatization by 2- naphthalenethiol
    • Hara S, Tsuchie M, Tsujioka R, Kimura M, Fujii M, Kuroda T, et al. High-performance liquid chromatographic quantification of busulfan in human serum after fluorescence derivatization by 2- naphthalenethiol. Anal Sci 2000; 16: 287-91.
    • (2000) Anal Sci , vol.16 , pp. 287-291
    • Hara, S.1    Tsuchie, M.2    Tsujioka, R.3    Kimura, M.4    Fujii, M.5    Kuroda, T.6
  • 69
    • 0030953276 scopus 로고    scopus 로고
    • Validation of a high-performance liquid chromatographic assay method for pharmacokinetic evaluation of busulfan
    • Heggie JR, Wu M, Burns RB, Ng CS, Fung HC, Knight G, et al. Validation of a high-performance liquid chromatographic assay method for pharmacokinetic evaluation of busulfan. J Chromatogr B Biomed Sci Appl 1997; 692(2): 437-44.
    • (1997) J Chromatogr B Biomed Sci Appl , vol.692 , Issue.2 , pp. 437-444
    • Heggie, J.R.1    Wu, M.2    Burns, R.B.3    Ng, C.S.4    Fung, H.C.5    Knight, G.6
  • 70
    • 26444477714 scopus 로고    scopus 로고
    • Tandem mass spectrometry method for the quantification of serum busulfan
    • Kellogg MD, Law T, Sakamoto M, Rifai N. Tandem mass spectrometry method for the quantification of serum busulfan. Ther Drug Monit 2005; 27: 625-9.
    • (2005) Ther Drug Monit , vol.27 , pp. 625-629
    • Kellogg, M.D.1    Law, T.2    Sakamoto, M.3    Rifai, N.4
  • 71
    • 0034919230 scopus 로고    scopus 로고
    • Sensitive and rapid quantification of busulfan in small plasma volumes by liquid chromatography-electrospray mass spectrometry
    • Murdter TE, Coller J, Claviez A, Schonberger F, Hofmann U, Dreger P, et al. Sensitive and rapid quantification of busulfan in small plasma volumes by liquid chromatography-electrospray mass spectrometry. Clin Chem 2001; 47: 1437-42.
    • (2001) Clin Chem , vol.47 , pp. 1437-1442
    • Murdter, T.E.1    Coller, J.2    Claviez, A.3    Schonberger, F.4    Hofmann, U.5    Dreger, P.6
  • 72
    • 0033064050 scopus 로고    scopus 로고
    • Determination of busulfan in human plasma using high-performance liquid chromatography with pre-column derivatization and fluorescence detection
    • Peris JE, Latorre JA, Castel V, Verdeguer A, Esteve S, Torres- Molina F. Determination of busulfan in human plasma using high-performance liquid chromatography with pre-column derivatization and fluorescence detection. J Chromatogr B Biomed Sci Appl 1999; 730: 33-40.
    • (1999) J Chromatogr B Biomed Sci Appl , vol.730 , pp. 33-40
    • Peris, J.E.1    Latorre, J.A.2    Castel, V.3    Verdeguer, A.4    Esteve, S.5    Torres- Molina, F.6
  • 74
    • 0032958943 scopus 로고    scopus 로고
    • High-performance liquid chromatographic method for quantification of busulfan in plasma after derivatization by tetrafluorothiophenol
    • Quernin MH, Poonkuzhali B, Medard Y, Dennison D, Srivastava A, Krishnamoorthy R, et al. High-performance liquid chromatographic method for quantification of busulfan in plasma after derivatization by tetrafluorothiophenol. J Chromatogr B Biomed Sci Appl 1999; 721: 147-52.
    • (1999) J Chromatogr B Biomed Sci Appl , vol.721 , pp. 147-152
    • Quernin, M.H.1    Poonkuzhali, B.2    Medard, Y.3    Dennison, D.4    Srivastava, A.5    Krishnamoorthy, R.6
  • 75
    • 0035813545 scopus 로고    scopus 로고
    • Quantification of busulfan in plasma by liquid chromatography-ion spray mass spectrometry. Application to pharmacokinetic studies in children
    • Quernin MH, Duval M, Litalien C, Vilmer E, Aigrain EJ. Quantification of busulfan in plasma by liquid chromatography-ion spray mass spectrometry. Application to pharmacokinetic studies in children. J Chromatogr B Biomed Sci Appl 2001; 763(1-2): 61-9.
    • (2001) J Chromatogr B Biomed Sci Appl , vol.763 , Issue.1-2 , pp. 61-69
    • Quernin, M.H.1    Duval, M.2    Litalien, C.3    Vilmer, E.4    Aigrain, E.J.5
  • 78
    • 0034749408 scopus 로고    scopus 로고
    • Population pharmacokinetic analysis resulting in a tool for dose individualization of busulphan in bone marrow transplantation recipients
    • Sandstrom M, Karlsson MO, Ljungman P, Hassan Z, Jonsson EN, Nilsson C, et al. Population pharmacokinetic analysis resulting in a tool for dose individualization of busulphan in bone marrow transplantation recipients. Bone Marrow Transplant 2001; 28: 657-64.
    • (2001) Bone Marrow Transplant , vol.28 , pp. 657-664
    • Sandstrom, M.1    Karlsson, M.O.2    Ljungman, P.3    Hassan, Z.4    Jonsson, E.N.5    Nilsson, C.6
  • 83
    • 0030727574 scopus 로고    scopus 로고
    • Relationship of plasma pharmacokinetics of high-dose oral busulfan to the outcome of allogeneic bone marrow transplantation in children with thalassemia
    • Pawlowska AB, Blazar BR, Angelucci E, Baronciani D, Shu XO, Bostrom B. Relationship of plasma pharmacokinetics of high-dose oral busulfan to the outcome of allogeneic bone marrow transplantation in children with thalassemia. Bone Marrow Transplant 1997; 20: 915-20.
    • (1997) Bone Marrow Transplant , vol.20 , pp. 915-920
    • Pawlowska, A.B.1    Blazar, B.R.2    Angelucci, E.3    Baronciani, D.4    Shu, X.O.5    Bostrom, B.6
  • 85
    • 0033832458 scopus 로고    scopus 로고
    • Individualizing high-dose oral busulfan: Prospective dose adjustment in a pediatric population undergoing allogeneic stem cell transplantation for advanced hematologic malignancies
    • Tran HT, Madden T, Petropoulos D, Worth LL, Felix EA, Sprigg-Saenz HA, et al. Individualizing high-dose oral busulfan: Prospective dose adjustment in a pediatric population undergoing allogeneic stem cell transplantation for advanced hematologic malignancies. Bone Marrow Transplant 2000; 26: 463-70.
    • (2000) Bone Marrow Transplant , vol.26 , pp. 463-470
    • Tran, H.T.1    Madden, T.2    Petropoulos, D.3    Worth, L.L.4    Felix, E.A.5    Sprigg-Saenz, H.A.6
  • 88
    • 0036672230 scopus 로고    scopus 로고
    • Busulfan concentration and graft rejection in pediatric patients undergoing hematopoietic stem cell transplantation
    • McCune JS, Gooley T, Gibbs JP, Sanders JE, Petersdorf EW, Appelbaum FR, et al. Busulfan concentration and graft rejection in pediatric patients undergoing hematopoietic stem cell transplantation. Bone Marrow Transplant 2002; 30: 167-73.
    • (2002) Bone Marrow Transplant , vol.30 , pp. 167-173
    • McCune, J.S.1    Gooley, T.2    Gibbs, J.P.3    Sanders, J.E.4    Petersdorf, E.W.5    Appelbaum, F.R.6
  • 89
    • 0037223471 scopus 로고    scopus 로고
    • Plasma pharmacokinetics of high-dose oral busulfan in children and adults undergoing bone marrow transplantation
    • Bostrom B, Enockson K, Johnson A, Bruns A, Blazar B. Plasma pharmacokinetics of high-dose oral busulfan in children and adults undergoing bone marrow transplantation. Pediatr Transplant 2003; 7 Suppl 3: 12-8.
    • (2003) Pediatr Transplant , vol.7 , Issue.SUPPL. 3 , pp. 12-18
    • Bostrom, B.1    Enockson, K.2    Johnson, A.3    Bruns, A.4    Blazar, B.5
  • 90
    • 34248196538 scopus 로고    scopus 로고
    • Influence of underlying disease on busulfan disposition in pediatric bone marrow transplant recipients: A non-parametric population pharmacokinetic study
    • Bertholle-Bonnet V, Bleyzac N, Galambrun C, Mialou V, Bertrand Y, Souillet G, et al. Influence of underlying disease on busulfan disposition in pediatric bone marrow transplant recipients: A non-parametric population pharmacokinetic study. Ther Drug Monit 2007; 29: 177-84.
    • (2007) Ther Drug Monit , vol.29 , pp. 177-184
    • Bertholle-Bonnet, V.1    Bleyzac, N.2    Galambrun, C.3    Mialou, V.4    Bertrand, Y.5    Souillet, G.6
  • 93
    • 0025121395 scopus 로고
    • Dose-dependent neurotoxicity of highdose busulfan in children: A clinical and pharmacological study
    • Vassal G, Deroussent A, Hartmann O, Challine D, Benhamou E, Valteau-Couanet D, et al. Dose-dependent neurotoxicity of highdose busulfan in children: A clinical and pharmacological study. Cancer Res 1990; 50: 6203-7.
    • (1990) Cancer Res , vol.50 , pp. 6203-6207
    • Vassal, G.1    Deroussent, A.2    Hartmann, O.3    Challine, D.4    Benhamou, E.5    Valteau-Couanet, D.6
  • 95
    • 0026611646 scopus 로고
    • Is 600 mg/m2 the appropriate dosage of busulfan in children undergoing bone marrow transplantation?
    • Vassal G, Deroussent A, Challine D, Hartmann O, Koscielny S, Valteau-Couanet D, et al. Is 600 mg/m2 the appropriate dosage of busulfan in children undergoing bone marrow transplantation? Blood 1992; 79: 2475-9.
    • (1992) Blood , vol.79 , pp. 2475-2479
    • Vassal, G.1    Deroussent, A.2    Challine, D.3    Hartmann, O.4    Koscielny, S.5    Valteau-Couanet, D.6
  • 96
    • 0026801441 scopus 로고
    • Optimization of busulfan dosage in children under-going bone marrow transplantation: A pharmacokinetic study of dose escalation
    • Yeager AM, Wagner JE, Jr., Graham ML, Jones RJ, Santos GW, Grochow LB. Optimization of busulfan dosage in children under-going bone marrow transplantation: A pharmacokinetic study of dose escalation. Blood 1992; 80: 2425-8.
    • (1992) Blood , vol.80 , pp. 2425-2428
    • Yeager, A.M.1    Wagner Jr., J.E.2    Graham, M.L.3    Jones, R.J.4    Santos, G.W.5    Grochow, L.B.6
  • 98
    • 0027179363 scopus 로고
    • Busulfan disposition below the age of three: Alteration in children with lysosomal storage disease
    • Vassa G, Fischer A, Challine D, Boland I, Ledheist F, Lemerle S, et al. Busulfan disposition below the age of three: Alteration in children with lysosomal storage disease. Blood 1993; 82: 1030-4.
    • (1993) Blood , vol.82 , pp. 1030-1034
    • Vassa, G.1    Fischer, A.2    Challine, D.3    Boland, I.4    Ledheist, F.5    Lemerle, S.6
  • 100
    • 0028017526 scopus 로고
    • Busulfan pharmacokinetics using a single daily high-dose regimen in children with acute leukemia
    • Shaw PJ, Scharping CE, Brian RJ, Earl JW. Busulfan pharmacokinetics using a single daily high-dose regimen in children with acute leukemia. Blood 1994; 84: 2357-62.
    • (1994) Blood , vol.84 , pp. 2357-2362
    • Shaw, P.J.1    Scharping, C.E.2    Brian, R.J.3    Earl, J.W.4
  • 101
    • 0029848690 scopus 로고    scopus 로고
    • Aspects concerning busulfan pharmacokinetics and bioavailability
    • Hassan M, Ehrsson H, Ljungman P. Aspects concerning busulfan pharmacokinetics and bioavailability. Leuk Lymphoma 1996; 22: 395-407
    • (1996) Leuk Lymphoma , vol.22 , pp. 395-407
    • Hassan, M.1    Ehrsson, H.2    Ljungman, P.3
  • 103
    • 0030818478 scopus 로고    scopus 로고
    • An improved limited sampling method for individualised busulphan dosing in bone marrow transplantation in children
    • Chattergoon DS, Saunders EF, Klein J, Calderwood S, Doyle J, Freedman MH, et al. An improved limited sampling method for individualised busulphan dosing in bone marrow transplantation in children. Bone Marrow Transplant 1997; 20: 347-54.
    • (1997) Bone Marrow Transplant , vol.20 , pp. 347-354
    • Chattergoon, D.S.1    Saunders, E.F.2    Klein, J.3    Calderwood, S.4    Doyle, J.5    Freedman, M.H.6
  • 104
    • 0031454073 scopus 로고    scopus 로고
    • Age-dependent tetrahydrothiophenium ion formation in young children and adults receiving high-dose busulfan
    • Gibbs JP, Murray G, Risler L, Chien JY, Dev R, Slattery JT. Age-dependent tetrahydrothiophenium ion formation in young children and adults receiving high-dose busulfan. Cancer Res 1997; 57: 5509-16.
    • (1997) Cancer Res , vol.57 , pp. 5509-5516
    • Gibbs, J.P.1    Murray, G.2    Risler, L.3    Chien, J.Y.4    Dev, R.5    Slattery, J.T.6
  • 105
    • 0031919721 scopus 로고    scopus 로고
    • Comparison of human liver and small intestinal glutathione S-transferase-catalyzed busulfan conjugation in vitro
    • Gibbs JP, Yang JS, Slattery JT. Comparison of human liver and small intestinal glutathione S-transferase-catalyzed busulfan conjugation in vitro. Drug Metab Dispos 1998; 26: 52-5.
    • (1998) Drug Metab Dispos , vol.26 , pp. 52-55
    • Gibbs, J.P.1    Yang, J.S.2    Slattery, J.T.3
  • 106
    • 0032744935 scopus 로고    scopus 로고
    • Upregulation of glutathione S-transferase activity in enterocytes of young children
    • Gibbs JP, Liacouras CA, Baldassano RN, Slattery JT. Upregulation of glutathione S-transferase activity in enterocytes of young children. Drug Metab Dispos 1999; 27: 1466-9.
    • (1999) Drug Metab Dispos , vol.27 , pp. 1466-1469
    • Gibbs, J.P.1    Liacouras, C.A.2    Baldassano, R.N.3    Slattery, J.T.4
  • 107
    • 0032848730 scopus 로고    scopus 로고
    • The role of busulfan in bone marrow transplantation
    • Hassan M. The role of busulfan in bone marrow transplantation. Med Oncol 1999; 16: 166-76.
    • (1999) Med Oncol , vol.16 , pp. 166-176
    • Hassan, M.1
  • 109
    • 0034016713 scopus 로고    scopus 로고
    • An evaluation of engraftment, toxicity and busulfan concentration in children receiving bone marrow transplantation for leukemia or genetic disease
    • Bolinger AM, Zangwill AB, Slattery JT, Glidden D, DeSantes K, Heyn L, et al. An evaluation of engraftment, toxicity and busulfan concentration in children receiving bone marrow transplantation for leukemia or genetic disease. Bone Marrow Transplant 2000; 25: 925-30
    • (2000) Bone Marrow Transplant , vol.25 , pp. 925-930
    • Bolinger, A.M.1    Zangwill, A.B.2    Slattery, J.T.3    Glidden, D.4    DeSantes, K.5    Heyn, L.6
  • 110
    • 0033625973 scopus 로고    scopus 로고
    • Retrospective appraisal of busulfan dose adjustment in children
    • Dupuis LL, Najdova M, Saunders EF. Retrospective appraisal of busulfan dose adjustment in children. Bone Marrow Transplant 2000; 26: 1143-7
    • (2000) Bone Marrow Transplant , vol.26 , pp. 1143-1147
    • Dupuis, L.L.1    Najdova, M.2    Saunders, E.F.3
  • 111
    • 0034062137 scopus 로고    scopus 로고
    • Consolidation with a busulfan-containing regimen followed by stem cell transplantation in infants with poor prognosis stage 4 neuroblastoma
    • Valteau-Couanet D, Benhamou E, Vassal G, Stambouli F, Lapierre V, Couanet D, et al. Consolidation with a busulfan-containing regimen followed by stem cell transplantation in infants with poor prognosis stage 4 neuroblastoma. Bone Marrow Transplant 2000; 25: 937-42.
    • (2000) Bone Marrow Transplant , vol.25 , pp. 937-942
    • Valteau-Couanet, D.1    Benhamou, E.2    Vassal, G.3    Stambouli, F.4    Lapierre, V.5    Couanet, D.6
  • 112
    • 0035193194 scopus 로고    scopus 로고
    • Evaluation of existing limited sampling models for busulfan kinetics in children with beta thalassaemia major undergoing bone marrow transplantation
    • Balasubramanian P, Chandy M, Krishnamoorthy R, Srivastava A. Evaluation of existing limited sampling models for busulfan kinetics in children with beta thalassaemia major undergoing bone marrow transplantation. Bone Marrow Transplant 2001; 28: 821-5.
    • (2001) Bone Marrow Transplant , vol.28 , pp. 821-825
    • Balasubramanian, P.1    Chandy, M.2    Krishnamoorthy, R.3    Srivastava, A.4
  • 113
    • 0034987068 scopus 로고    scopus 로고
    • Oral busulfan pharmacokinetics and engraftment in children with Hurler syndrome and other inherited metabolic storage diseases undergoing hematopoietic cell transplantation
    • Jacobson P, Park JJ, DeFor TE, Thrall M, Abel S, Krivit W, et al. Oral busulfan pharmacokinetics and engraftment in children with Hurler syndrome and other inherited metabolic storage diseases undergoing hematopoietic cell transplantation, Bone Marrow Transplant 2001; 27: 855-61.
    • (2001) Bone Marrow Transplant , vol.27 , pp. 855-861
    • Jacobson, P.1    Park, J.J.2    DeFor, T.E.3    Thrall, M.4    Abel, S.5    Krivit, W.6
  • 114
    • 0035115017 scopus 로고    scopus 로고
    • Glutathione S-transferase activity influences busulfan pharmacokinetics in patients with beta thalassemia major undergoing bone marrow transplantation
    • Poonkuzhali B, Chandy M, Srivastava A, Dennison D, Krishnamoorthy R. Glutathione S-transferase activity influences busulfan pharmacokinetics in patients with beta thalassemia major undergoing bone marrow transplantation. Drug Metab Dispos 2001; 29: 264-7.
    • (2001) Drug Metab Dispos , vol.29 , pp. 264-267
    • Poonkuzhali, B.1    Chandy, M.2    Srivastava, A.3    Dennison, D.4    Krishnamoorthy, R.5
  • 115
    • 0344034840 scopus 로고    scopus 로고
    • In children and adolescents, the pharmacodynamics of high-dose busulfan is dependent on the second alkylating agent used in the combined regimen (melphalan or thiotepa)
    • Bouligand J, Boland I, Valteau-Couanet D, Deroussent A, Kalifa C, Hartmann O, et al. In children and adolescents, the pharmacodynamics of high-dose busulfan is dependent on the second alkylating agent used in the combined regimen (melphalan or thiotepa). Bone Marrow Transplant 2003; 32: 979-86.
    • (2003) Bone Marrow Transplant , vol.32 , pp. 979-986
    • Bouligand, J.1    Boland, I.2    Valteau-Couanet, D.3    Deroussent, A.4    Kalifa, C.5    Hartmann, O.6
  • 116
    • 0038702469 scopus 로고    scopus 로고
    • Retrospective appraisal of busulfan dose adjustment in children
    • Dupuis LL, Najdova M, Saunders EF. Retrospective appraisal of busulfan dose adjustment in children. Bone Marrow Transplant 2003; 31: 729.
    • (2003) Bone Marrow Transplant , vol.31 , pp. 729
    • Dupuis, L.L.1    Najdova, M.2    Saunders, E.F.3
  • 118
    • 4344712956 scopus 로고    scopus 로고
    • Busulphan given as four single daily doses of 150 mg/m2 is safe and effective in children of all ages
    • Shaw PJ, Nath C, Berry A, Earl JW. Busulphan given as four single daily doses of 150 mg/m2 is safe and effective in children of all ages. Bone Marrow Transplant 2004; 34: 197-205.
    • (2004) Bone Marrow Transplant , vol.34 , pp. 197-205
    • Shaw, P.J.1    Nath, C.2    Berry, A.3    Earl, J.W.4
  • 119
    • 39749200992 scopus 로고    scopus 로고
    • Risk-adjusted monitoring of veno-occlusive disease following Bayesian individualization of busulfan dosage for bone marrow transplantation in paediatrics
    • Brice K, Valerie B, Claire G, Valerie M, Yves B, Gilles A, et al. Risk-adjusted monitoring of veno-occlusive disease following Bayesian individualization of busulfan dosage for bone marrow transplantation in paediatrics. Pharmacoepidemiol Drug Saf 2008; 17(2): 135-43.
    • (2008) Pharmacoepidemiol Drug Saf , vol.17 , Issue.2 , pp. 135-143
    • Brice, K.1    Valerie, B.2    Claire, G.3    Valerie, M.4    Yves, B.5    Gilles, A.6
  • 120
    • 0035179652 scopus 로고    scopus 로고
    • Improved clinical outcome of paediatric bone marrow recipients using a test dose and Bayesian pharmacokinetic idividualization of busulfan dosage regimens
    • Bleyzac N, Souillet G, Magron P, Janoly A, Martin P, Bertrand Y, et al. Improved clinical outcome of paediatric bone marrow recipients using a test dose and Bayesian pharmacokinetic idividualization of busulfan dosage regimens. Bone Marrow Transplant 2001; 28: 743-51.
    • (2001) Bone Marrow Transplant , vol.28 , pp. 743-751
    • Bleyzac, N.1    Souillet, G.2    Magron, P.3    Janoly, A.4    Martin, P.5    Bertrand, Y.6
  • 122
    • 27844545839 scopus 로고    scopus 로고
    • Chandy M, Balasubramanian P, Ramachandran SV, Mathews V, George B, Dennison D, et al. Randomized trial of two different conditioning regimens for bone marrow transplantation in thalassemia - the role of busulfan pharmacokinetics in determining outcome. Bone Marrow Transplant 20051; 36: 839-45.
    • Chandy M, Balasubramanian P, Ramachandran SV, Mathews V, George B, Dennison D, et al. Randomized trial of two different conditioning regimens for bone marrow transplantation in thalassemia - the role of busulfan pharmacokinetics in determining outcome. Bone Marrow Transplant 20051; 36: 839-45.
  • 123
  • 124
    • 33646839143 scopus 로고    scopus 로고
    • Influence of glutathione S-transferase A1 polymorphism on the pharmacokinetics of busulfan
    • Kusama M, Kubota T, Matsukura Y, Matsuno K, Ogawa S, Kanda Y, et al. Influence of glutathione S-transferase A1 polymorphism on the pharmacokinetics of busulfan. Clin Chim Acta 2006; 368: 93-8.
    • (2006) Clin Chim Acta , vol.368 , pp. 93-98
    • Kusama, M.1    Kubota, T.2    Matsukura, Y.3    Matsuno, K.4    Ogawa, S.5    Kanda, Y.6
  • 125
    • 0021123313 scopus 로고
    • Binding of busulfan to plasma proteins and blood cells
    • Ehrsson H, Hassan M. Binding of busulfan to plasma proteins and blood cells. J Pharm Pharmacol 1984; 36: 694-6.
    • (1984) J Pharm Pharmacol , vol.36 , pp. 694-696
    • Ehrsson, H.1    Hassan, M.2
  • 126
    • 33846424934 scopus 로고    scopus 로고
    • Induction of glutathione synthesis explains pharmacodynamics of high-dose busulfan in mice and highlights putative mechanisms of drug interaction
    • Bouligand J, Deroussent A, Simonnard N, Opolon P, Morizet J, Connault E, et al. Induction of glutathione synthesis explains pharmacodynamics of high-dose busulfan in mice and highlights putative mechanisms of drug interaction. Drug Metab Dispos 2007; 35: 306-14.
    • (2007) Drug Metab Dispos , vol.35 , pp. 306-314
    • Bouligand, J.1    Deroussent, A.2    Simonnard, N.3    Opolon, P.4    Morizet, J.5    Connault, E.6
  • 127
    • 0029840656 scopus 로고    scopus 로고
    • Busulfan conjugation by glutathione S-transferases alpha, mu, and pi
    • Czerwinski M, Gibbs JP, Slattery JT. Busulfan conjugation by glutathione S-transferases alpha, mu, and pi. Drug Metab Dispos 1996; 24: 1015-9
    • (1996) Drug Metab Dispos , vol.24 , pp. 1015-1019
    • Czerwinski, M.1    Gibbs, J.P.2    Slattery, J.T.3
  • 128
    • 0029765411 scopus 로고    scopus 로고
    • Busulfan-glutathione conjugation catalyzed by human liver cytosolic glutathione S-transferases
    • Gibbs JP, Czerwinski M, Slattery JT. Busulfan-glutathione conjugation catalyzed by human liver cytosolic glutathione S-transferases. Cancer Res 1996; 56: 3678-81.
    • (1996) Cancer Res , vol.56 , pp. 3678-3681
    • Gibbs, J.P.1    Czerwinski, M.2    Slattery, J.T.3
  • 129
    • 0031032786 scopus 로고    scopus 로고
    • Higher frequency of glutathione S-transferase deletions in black children with acute lymphoblastic leukemia
    • Chen CL, Liu Q, Pui CH, Rivera GK, Sandlund JT, Ribeiro R, et al. Higher frequency of glutathione S-transferase deletions in black children with acute lymphoblastic leukemia. Blood 1997; 89: 1701-7.
    • (1997) Blood , vol.89 , pp. 1701-1707
    • Chen, C.L.1    Liu, Q.2    Pui, C.H.3    Rivera, G.K.4    Sandlund, J.T.5    Ribeiro, R.6
  • 130
    • 33947732450 scopus 로고    scopus 로고
    • Glutathione S-transferase A1 polymorphisms and acute graft-vs.-host disease in HLA-matched sibling allogencic hematopoietic stem cell transplantation
    • Kim I, Keam B, Lee KH, Kim JH, Oh SY, Ra EK, et al. Glutathione S-transferase A1 polymorphisms and acute graft-vs.-host disease in HLA-matched sibling allogencic hematopoietic stem cell transplantation. Clin Transplant 2007; 21: 207-13.
    • (2007) Clin Transplant , vol.21 , pp. 207-213
    • Kim, I.1    Keam, B.2    Lee, K.H.3    Kim, J.H.4    Oh, S.Y.5    Ra, E.K.6
  • 131
    • 34648843006 scopus 로고    scopus 로고
    • Cytochrome P450 2C19 loss-of-function polymorphism is associated with an increased treatment-related mortality in patients undergoing allogeneic transplantation
    • Elmaagacli AH, Koldehoff M, Steckel NK, Trenschel R, Ottinger H, Beelen DW. Cytochrome P450 2C19 loss-of-function polymorphism is associated with an increased treatment-related mortality in patients undergoing allogeneic transplantation. Bone Marrow Transplant 2007; 40: 659-64.
    • (2007) Bone Marrow Transplant , vol.40 , pp. 659-664
    • Elmaagacli, A.H.1    Koldehoff, M.2    Steckel, N.K.3    Trenschel, R.4    Ottinger, H.5    Beelen, D.W.6
  • 132
    • 0034960016 scopus 로고    scopus 로고
    • Busulfan levels are influenced by prior treatment and are associated with hepatic veno-occlusive disease and early mortality but not with delayed complications following marrow transplantation
    • Copelan EA, Bechtel TP, Avalos BR, Elder PJ, Ezzone SA, Scholl MD, et al. Busulfan levels are influenced by prior treatment and are associated with hepatic veno-occlusive disease and early mortality but not with delayed complications following marrow transplantation. Bone Marrow Transplant 2001; 27: 1121-4.
    • (2001) Bone Marrow Transplant , vol.27 , pp. 1121-1124
    • Copelan, E.A.1    Bechtel, T.P.2    Avalos, B.R.3    Elder, P.J.4    Ezzone, S.A.5    Scholl, M.D.6
  • 133
    • 9444277948 scopus 로고    scopus 로고
    • Itraconazole can increase systemic exposure to busulfan in patients given bone marrow transplantation. GITMO (Gruppo Italiano Trapianto di Midollo Osseo)
    • Buggia I, Zecca M, Alessandrino EP, Locatelli F, Rosti G, Bosi A, et al. Itraconazole can increase systemic exposure to busulfan in patients given bone marrow transplantation. GITMO (Gruppo Italiano Trapianto di Midollo Osseo). Anticancer Res 1996; 16: 2083-8.
    • (1996) Anticancer Res , vol.16 , pp. 2083-2088
    • Buggia, I.1    Zecca, M.2    Alessandrino, E.P.3    Locatelli, F.4    Rosti, G.5    Bosi, A.6
  • 134
    • 0242669388 scopus 로고    scopus 로고
    • The effect of metronidazole on busulfan pharmacokinetics in patients undergoing hematopoietic stem cell transplantation
    • Nilsson C, Aschan J, Hentschke P, Ringden O, Ljungman P, Hassan M. The effect of metronidazole on busulfan pharmacokinetics in patients undergoing hematopoietic stem cell transplantation. Bone Marrow Transplant 2003; 31: 429-35.
    • (2003) Bone Marrow Transplant , vol.31 , pp. 429-435
    • Nilsson, C.1    Aschan, J.2    Hentschke, P.3    Ringden, O.4    Ljungman, P.5    Hassan, M.6
  • 135
    • 0025250254 scopus 로고
    • Is dose normalization to weight or body surface area useful in adults?
    • Grochow LB, Baraldi C, Noe D. Is dose normalization to weight or body surface area useful in adults? J Natl Cancer Inst 1990; 82: 323-5.
    • (1990) J Natl Cancer Inst , vol.82 , pp. 323-325
    • Grochow, L.B.1    Baraldi, C.2    Noe, D.3
  • 137
    • 0030902219 scopus 로고    scopus 로고
    • Marrow transplantation for chronic myeloid leukemia: The influence of plasma busulfan levels on the outcome of transplantation
    • Slattery JT, Clift RA, Buckner CD, Radich J, Storer B, Bensinger WI, et al. Marrow transplantation for chronic myeloid leukemia: The influence of plasma busulfan levels on the outcome of transplantation. Blood 1997; 89: 3055-60.
    • (1997) Blood , vol.89 , pp. 3055-3060
    • Slattery, J.T.1    Clift, R.A.2    Buckner, C.D.3    Radich, J.4    Storer, B.5    Bensinger, W.I.6
  • 138
    • 33750205692 scopus 로고    scopus 로고
    • Impact of conditioning regimen intensity on outcome of allogeneic hematopoietic cell transplantation for advanced acute myelogenous leukemia and myelodysplastic syndrome
    • Alyea EP, Kim HT, Ho V, Cutler C, DeAngelo DJ, Stone R, et al. Impact of conditioning regimen intensity on outcome of allogeneic hematopoietic cell transplantation for advanced acute myelogenous leukemia and myelodysplastic syndrome. Biol Blood Marrow Transplant 2006; 12: 1047-55.
    • (2006) Biol Blood Marrow Transplant , vol.12 , pp. 1047-1055
    • Alyea, E.P.1    Kim, H.T.2    Ho, V.3    Cutler, C.4    DeAngelo, D.J.5    Stone, R.6
  • 140
    • 0024345093 scopus 로고
    • Pharmacokinetics of busulfan: Correlation with venoocclusive disease in patients undergoing bone marrow transplantation
    • Grochow LB, Jones RJ, Brundrett RB, Braine HG, Chen TL, Saral R, et al. Pharmacokinetics of busulfan: Correlation with venoocclusive disease in patients undergoing bone marrow transplantation. Cancer Chemother Pharmacol 1989; 25: 55-61.
    • (1989) Cancer Chemother Pharmacol , vol.25 , pp. 55-61
    • Grochow, L.B.1    Jones, R.J.2    Brundrett, R.B.3    Braine, H.G.4    Chen, T.L.5    Saral, R.6
  • 141
    • 0027478056 scopus 로고
    • Veno-occlusive disease of the liver and multiorgan failure after bone marrow transplantation: A cohort study of 355 patients
    • McDonald GB, Sharma P, Matthews DE, Shulman HM, Thomas ED. Veno-occlusive disease of the liver and multiorgan failure after bone marrow transplantation: A cohort study of 355 patients. Ann Intern Med 1993; 118: 255-67.
    • (1993) Ann Intern Med , vol.118 , pp. 255-267
    • McDonald, G.B.1    Sharma, P.2    Matthews, D.E.3    Shulman, H.M.4    Thomas, E.D.5
  • 143
    • 0036125693 scopus 로고    scopus 로고
    • Toxic injury to hepatic sinusoids: Sinusoidal obstruction syndrome (veno-occlusive disease)
    • DeLeve LD, Shulman HM, McDonald GB. Toxic injury to hepatic sinusoids: sinusoidal obstruction syndrome (veno-occlusive disease). Semin Liver Dis 2002; 22: 27-42.
    • (2002) Semin Liver Dis , vol.22 , pp. 27-42
    • DeLeve, L.D.1    Shulman, H.M.2    McDonald, G.B.3
  • 144
    • 0021363719 scopus 로고
    • Venocclusive disease of the liver after bone marrow transplantation: Diagnosis, incidence, and predisposing factors
    • McDonald GB, Sharma P, Matthews DE, Shulman HM, Thomas ED. Venocclusive disease of the liver after bone marrow transplantation: Diagnosis, incidence, and predisposing factors. Hepatology 1984; 4: 116-22.
    • (1984) Hepatology , vol.4 , pp. 116-122
    • McDonald, G.B.1    Sharma, P.2    Matthews, D.E.3    Shulman, H.M.4    Thomas, E.D.5
  • 145
    • 0032533633 scopus 로고    scopus 로고
    • Incidence and outcome of hepatic veno-occlusive disease after blood or marrow transplantation: A prospective cohort study of the European Group for Blood and Marrow Transplantation. European Group for Blood and Marrow Transplantation Chronic Leukemia Working Party
    • Carreras E, Bertz H, Arcese W, Vernant JP, Tomas JF, Hagglund H, et al. Incidence and outcome of hepatic veno-occlusive disease after blood or marrow transplantation: A prospective cohort study of the European Group for Blood and Marrow Transplantation. European Group for Blood and Marrow Transplantation Chronic Leukemia Working Party. Blood 1998; 92: 3599-604.
    • (1998) Blood , vol.92 , pp. 3599-3604
    • Carreras, E.1    Bertz, H.2    Arcese, W.3    Vernant, J.P.4    Tomas, J.F.5    Hagglund, H.6
  • 146
    • 0026759834 scopus 로고
    • Risk factors for hepatic veno-occlusive disease after high-dose busulfan-containing regimens followed by autologous bone marrow transplantation: A study in 136 children
    • Meresse V, Hartmann O, Vassal G, Benhamou E, Valteau-Couanet D, Brugieres L, et al. Risk factors for hepatic veno-occlusive disease after high-dose busulfan-containing regimens followed by autologous bone marrow transplantation: A study in 136 children. Bone Marrow Transplant 1992; 10: 135-41.
    • (1992) Bone Marrow Transplant , vol.10 , pp. 135-141
    • Meresse, V.1    Hartmann, O.2    Vassal, G.3    Benhamou, E.4    Valteau-Couanet, D.5    Brugieres, L.6
  • 147
    • 0030770990 scopus 로고    scopus 로고
    • High busulfan concentrations are associated with increased transplant-related mortality in allogeneic bone marrow transplant patients
    • Ljungman P, Hassan M, Bekassy AN, Ringden O, Oberg G. High busulfan concentrations are associated with increased transplant-related mortality in allogeneic bone marrow transplant patients. Bone Marrow Transplant 1997; 20: 909-13.
    • (1997) Bone Marrow Transplant , vol.20 , pp. 909-913
    • Ljungman, P.1    Hassan, M.2    Bekassy, A.N.3    Ringden, O.4    Oberg, G.5
  • 148
    • 0038644880 scopus 로고    scopus 로고
    • HLA-matched related hematopoietic cell transplantation for chronic-phase CML using a targeted busulfan and cyclophosphamide preparative regimen
    • Radich JP, Gooley T, Bensinger W, Chauncey T, Clift R, Flowers M, et al. HLA-matched related hematopoietic cell transplantation for chronic-phase CML using a targeted busulfan and cyclophosphamide preparative regimen. Blood 2003; 102: 31-5.
    • (2003) Blood , vol.102 , pp. 31-35
    • Radich, J.P.1    Gooley, T.2    Bensinger, W.3    Chauncey, T.4    Clift, R.5    Flowers, M.6
  • 149
    • 0034021677 scopus 로고    scopus 로고
    • The effect of busulphan on the pharmacokinetics of cyclophosphamide and its 4-hydroxy metabolite: Time interval influence on therapeutic efficacy and therapy-related toxicity
    • Hassan M, Ljungman P, Ringden O, Hassan Z, Oberg G, Nilsson C, et al. The effect of busulphan on the pharmacokinetics of cyclophosphamide and its 4-hydroxy metabolite: Time interval influence on therapeutic efficacy and therapy-related toxicity. Bone Marrow Transplant 2000; 25: 915-24.
    • (2000) Bone Marrow Transplant , vol.25 , pp. 915-924
    • Hassan, M.1    Ljungman, P.2    Ringden, O.3    Hassan, Z.4    Oberg, G.5    Nilsson, C.6
  • 150
    • 34250206633 scopus 로고    scopus 로고
    • Cyclophosphamide following targeted oral busulfan as conditioning for hematopoietic cell transplantation: Pharmacokinetics, liver toxicity, and mortality
    • McCune JS, Batchelder A, Deeg HJ, Gooley T, Cole S, Phillips B, et al. Cyclophosphamide following targeted oral busulfan as conditioning for hematopoietic cell transplantation: Pharmacokinetics, liver toxicity, and mortality. Biol Blood Marrow Transplant 2007; 13: 853-62.
    • (2007) Biol Blood Marrow Transplant , vol.13 , pp. 853-862
    • McCune, J.S.1    Batchelder, A.2    Deeg, H.J.3    Gooley, T.4    Cole, S.5    Phillips, B.6
  • 151
    • 0029809978 scopus 로고    scopus 로고
    • Cellular target of cyclophosphamide toxicity in the murine liver: Role of glutathione and site of metabolic activation
    • DeLeve LD. Cellular target of cyclophosphamide toxicity in the murine liver: Role of glutathione and site of metabolic activation. Hepatology 1996; 24: 830-7.
    • (1996) Hepatology , vol.24 , pp. 830-837
    • DeLeve, L.D.1
  • 152
    • 11444254918 scopus 로고    scopus 로고
    • Targeted busulfan and cyclophosphamide as compared to busulfan and TBI as preparative regimens for transplantation in patients with advanced MDS or transformation to AML
    • Scott B, Deeg HJ, Storer B, Chauncey T, Petersdorf S, Slattery J, et al. Targeted busulfan and cyclophosphamide as compared to busulfan and TBI as preparative regimens for transplantation in patients with advanced MDS or transformation to AML. Leuk Lymphoma 2004; 45: 2409-17.
    • (2004) Leuk Lymphoma , vol.45 , pp. 2409-2417
    • Scott, B.1    Deeg, H.J.2    Storer, B.3    Chauncey, T.4    Petersdorf, S.5    Slattery, J.6
  • 153
    • 0037370735 scopus 로고    scopus 로고
    • Cyclophosphamide metabolism, liver toxicity, and mortality following hematopoietic stem cell transplantation
    • McDonald GB, Slattery JT, Bouvier ME, Ren S, Batchelder AL, Kalhorn TF, et al. Cyclophosphamide metabolism, liver toxicity, and mortality following hematopoietic stem cell transplantation. Blood 2003; 101: 2043-8.
    • (2003) Blood , vol.101 , pp. 2043-2048
    • McDonald, G.B.1    Slattery, J.T.2    Bouvier, M.E.3    Ren, S.4    Batchelder, A.L.5    Kalhorn, T.F.6
  • 154
    • 33745011812 scopus 로고    scopus 로고
    • Absence of veno-occlussive disease in a cohort of multiple myeloma patients undergoing autologous stem cell transplantation with targeted busulfan dosage
    • Clopes A, Sureda A, Sierra J, Queralto JM, Broto A, Farre R, et al. Absence of veno-occlussive disease in a cohort of multiple myeloma patients undergoing autologous stem cell transplantation with targeted busulfan dosage. Eur J Haematol 2006; 77: 1-6.
    • (2006) Eur J Haematol , vol.77 , pp. 1-6
    • Clopes, A.1    Sureda, A.2    Sierra, J.3    Queralto, J.M.4    Broto, A.5    Farre, R.6
  • 156
    • 0036401557 scopus 로고    scopus 로고
    • Parenteral busulfan: Is therapeutic monitoring still warranted?
    • Grochow LB. Parenteral busulfan: Is therapeutic monitoring still warranted? Biol Blood Marrow Transplant 2002; 8: 465-7.
    • (2002) Biol Blood Marrow Transplant , vol.8 , pp. 465-467
    • Grochow, L.B.1
  • 157
    • 0037103191 scopus 로고    scopus 로고
    • Conditioning with targeted busulfan and cyclophosphamide for hemopoietic stem cell transplantation from related and unrelated donors in patients with myelodysplastic syndrome
    • Deeg HJ, Storer B, Slattery JT, Anasetti C, Doney KC, Hansen JA, et al. Conditioning with targeted busulfan and cyclophosphamide for hemopoietic stem cell transplantation from related and unrelated donors in patients with myelodysplastic syndrome. Blood 2002; 100: 1201-7.
    • (2002) Blood , vol.100 , pp. 1201-1207
    • Deeg, H.J.1    Storer, B.2    Slattery, J.T.3    Anasetti, C.4    Doney, K.C.5    Hansen, J.A.6
  • 158
    • 2542592386 scopus 로고    scopus 로고
    • A simple approximation for busulfan dose adjustment in adult patients undergoing bone marrow transplantation
    • Hoffer E, Akria L, Tabak A, Scherb I, Rowe JM, Krivoy N. A simple approximation for busulfan dose adjustment in adult patients undergoing bone marrow transplantation. Ther Drug Monit 2004; 26: 331-5.
    • (2004) Ther Drug Monit , vol.26 , pp. 331-335
    • Hoffer, E.1    Akria, L.2    Tabak, A.3    Scherb, I.4    Rowe, J.M.5    Krivoy, N.6
  • 159
    • 0034805016 scopus 로고    scopus 로고
    • Monitoring of busulfan area under the curve: Estimation by a single measurement
    • Tabak A, Hoffer E, Rowe JM, Krivoy N. Monitoring of busulfan area under the curve: Estimation by a single measurement. Ther Drug Monit 2001; 23: 526-8.
    • (2001) Ther Drug Monit , vol.23 , pp. 526-528
    • Tabak, A.1    Hoffer, E.2    Rowe, J.M.3    Krivoy, N.4
  • 160
    • 2942571352 scopus 로고    scopus 로고
    • Intraindividual variability in busulfan pharmacokinetics in patients undergoing a bone marrow transplant: Assessment of a test dose and first dose strategy
    • Lindley C, Shea T, McCune J, Shord S, Decker J, Harvey D, et al. Intraindividual variability in busulfan pharmacokinetics in patients undergoing a bone marrow transplant: Assessment of a test dose and first dose strategy. Anticancer Drugs 2004; 15: 453-9.
    • (2004) Anticancer Drugs , vol.15 , pp. 453-459
    • Lindley, C.1    Shea, T.2    McCune, J.3    Shord, S.4    Decker, J.5    Harvey, D.6
  • 161
    • 36048947430 scopus 로고    scopus 로고
    • Individual dose adjustment of oral busulfan using a test dose in hematopoietic stem cell transplantation
    • Takamatsu Y, Sasaki N, Eto T, Nagafuji K, Abe Y, Choi I, et al. Individual dose adjustment of oral busulfan using a test dose in hematopoietic stem cell transplantation. Int J Hematol 2007; 86: 261-8.
    • (2007) Int J Hematol , vol.86 , pp. 261-268
    • Takamatsu, Y.1    Sasaki, N.2    Eto, T.3    Nagafuji, K.4    Abe, Y.5    Choi, I.6
  • 162
    • 0032529287 scopus 로고    scopus 로고
    • Long-term follow-Up of a randomized trial of two irradiation regimens for patients receiving allogeneic marrow transplants during first remission of acute myeloid leukemia
    • Clift RA, Buckner CD, Appelbaum FR, Sullivan KM, Storb R, Thomas ED. Long-term follow-Up of a randomized trial of two irradiation regimens for patients receiving allogeneic marrow transplants during first remission of acute myeloid leukemia. Blood 1998; 92: 1455-6.
    • (1998) Blood , vol.92 , pp. 1455-1456
    • Clift, R.A.1    Buckner, C.D.2    Appelbaum, F.R.3    Sullivan, K.M.4    Storb, R.5    Thomas, E.D.6


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