Therapeutic monitoring of busulfan in pediatric bone marrow transplantation

Pediatric Hematology and Oncology

Volumn 19, Issue 1, 2002, Pages 31-37

  Krivoy, N ^a   Hoffer, E ^a   Tabak, A ^a   Elhasid, R ^a   Arush, M Weyl Ben ^a   Stein, J ^a   Yaniv, I ^a   Rowe, J M ^a  

^a RAMBAM MEDICAL CENTER   (Israel)

Author keywords

Bone marrow transplantation; Busulfan; Children; Dose adjustment

Indexed keywords

ANTINEOPLASTIC AGENT; BUSULFAN;

AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; BONE MARROW TRANSPLANTATION; CANCER CHEMOTHERAPY; CHILD; CHILDHOOD LEUKEMIA; CLINICAL ARTICLE; DRUG DISPOSITION; DRUG HALF LIFE; DRUG MONITORING; HEMATOPOIETIC SYSTEM TUMOR; HUMAN; SIDE EFFECT;

ANIMALS; ANTINEOPLASTIC AGENTS, ALKYLATING; AREA UNDER CURVE; BONE MARROW TRANSPLANTATION; BUSULFAN; CHILD; CHILD, PRESCHOOL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG MONITORING; HUMANS; INFANT; PROSPECTIVE STUDIES; TISSUE DISTRIBUTION;

EID: 0036086354     PISSN: 08880018     EISSN: None     Source Type: Journal    
DOI: 10.1080/088800102753356167     Document Type: Article

References (12)

1. Busulfan disposition: The role of therapeutic monitoring in bone marrow transplantation induction regimens
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4. The impact of obesity and disease on busulfan oral clearance in adults
5. Accidental busulfan overdose: Enhanced drug clearance with hemodialysis in a child with Wiskott-Aldrich syndrome
6. Individualizing high-dose oral busulfan: Prospective dose adjustment in a pediatric population undergoing allogeneic stem cell transplantation for advanced hematological malignancies
7. Relationship of plasma pharmacokinetics of high-dose oral busulfan to the outcome of allogeneic bone marrow transplantation in children with thalassemia
8. Venoocclusive disease of the liver after bone marrow transplantation: Diagnosis, incidence, and predisposing factors
9. Busulfan disposition and hepatic veno-occlusive disease in children undergoing bone marrow transplantation
10. Association of busulfan area under the curve with veno-occlusive disease following BMT
11. Marrow transplantation for chronic myeloid leukemia: The influence of plasma busulfan levels on the outcome of transplantation
12. An evaluation of engraftment, toxicity and busulfan concentration in children receiving bone marrow transplantation for leukemia or genetic disease