Characterization of rat heart alkaline phosphatase isoenzymes and modulation of activity

Brazilian Journal of Medical and Biological Research

Volumn 41, Issue 7, 2008, Pages 600-609

  Mota, A ^a   Silva, P ^a   Neves, D ^a   Lemos, C ^a   Calhau, C ^a   Torres, D ^a   Martel, F ^a   Fraga, H ^a   Ribeiro, L ^a   Alcada M N M P ^a   Pinho, M J ^a   Negrao M R ^a   Pedrosa, R ^a   Guerreiro, S ^a   Guimaraes J T ^a   Azevedo, I ^a   Martins, M J ^a  

^a University of Porto   (Portugal)

Author keywords

Alkaline phosphatase; Heart; Methylxanthines; Polyphenol rich beverages; Steroid hormones

Indexed keywords

4 NITROPHENOL; 4 NITROPHENYL PHOSPHATE; ACETYLSALICYLIC ACID; ALKALINE PHOSPHATASE; ALKALINE PHOSPHATASE HEART ISOENZYME; ATENOLOL; CAFFEINE; CORTICOSTERONE; ESTRADIOL; LEVAMISOLE; PHENYLALANINE; POLYPHENOL; PROGESTERONE; PROPRANOLOL; SIMVASTATIN; THEOPHYLLINE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; DRUG TARGETING; ENZYME ACTIVITY; ENZYME INHIBITION; HEART PROTECTION; IMMUNOFLUORESCENCE; IN VITRO STUDY; MALE; NONHUMAN; PROTEIN LOCALIZATION; QUANTITATIVE ANALYSIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WISTAR RAT;

RATTUS; RATTUS NORVEGICUS;

EID: 52949094290     PISSN: 0100879X     EISSN: 1414431X     Source Type: Journal    
DOI: 10.1590/S0100-879X2008000700009     Document Type: Article

References (40)

1. Hui M, Tenenbaum HC. New face of an old enzyme: alkaline phosphatase may contribute to human tissue aging by inducing tissue hardening and calcification. Anat Rec 1998; 253: 91-94.
2. Van Hoof V, De Broe ME. Interpretation and clinical significance of alkaline phosphatase isoenzyme patterns. Crit Rev Clin Lab Sci 1994; 31: 197-293.
3. Fedde KN, Blair L, Silverstein J, Coburn SP, Ryan LM, Weinstein RS, et al. Alkaline phosphatase knock-out mice recapitulate the metabolic and skeletal defects of infantile hypophosphatasia. J Bone Miner Res 1999; 14: 2015-2026.
4. Narisawa S, Huang L, Iwasaki A, Hasegawa H, Alpers DH, Millan JL. Accelerated fat absorption in intestinal alkaline phosphatase knockout mice. Mol Cell Biol 2003; 23: 7525-7530.
5. Schultz-Hector S, Balz K, Bohm M, Ikehara Y, Rieke L. Cellular localization of endothelial alkaline phosphatase reaction product and enzyme protein in the myocardium. J Histochem Cytochem 1993; 41: 1813-1821.
6. Chen NX, Moe SM. Arterial calcification in diabetes. Curr Diab Rep 2003; 3: 28-32.
7. Mathieu P, Voisine P, Pepin A, Shetty R, Savard N, Dagenais F. Calcification of human valve interstitial cells is dependent on alkaline phosphatase activity. J Heart Valve Dis 2005; 14: 353-357.
8. Rajamannan NM, Subramaniam M, Rickard D, Stock SR, Donovan J, Springett M, et al. Human aortic valve calcification is associated with an osteoblast phenotype. Circulation 2003; 107: 2181-2184.
9. Kizu A, Shioi A, Jono S, Koyama H, Okuno Y, Nishizawa Y. Statins inhibit in vitro calcification of human vascular smooth muscle cells induced by inflammatory mediators. J Cell Biochem 2004; 93: 1011-1019.
10. Vasudev SC, Chandy T, Sharma CP, Mohanty M, Umasankar PR. Synergistic effect of released aspirin/heparin for preventing bovine pericardial calcification. Artif Organs 2000; 24: 129-136.
11. Clark-Greuel JN, Connolly JM, Sorichillo E, Narula NR, Rapoport HS, Mohler ER III, et al. Transforming growth factor-beta1 mechanisms in aortic valve calcification: increased alkaline phosphatase and related events. Ann Thorac Surg 2007; 83: 946-953.
12. Domar U, Nilsson B, Baranov V, Gerdes U, Stigbrand T. Expression of intestinal alkaline phosphatase in human organs. Histochemistry 1992; 98: 359-364.
13. Martins MJ, Negrao MR, Hipolito-Reis C. Alkaline phosphatase from rat liver and kidney is differentially modulated. Clin Biochem 2001; 34: 463-468.
14. Calhau C, Martel F, Pinheiro-Silva S, Pinheiro H, Soaresda-Silva P, Hipolito-Reis C, et al. Modulation of insulin transport in rat brain microvessel endothelial cells by an ectophosphatase activity. J Cell Biochem 2002; 84: 389-400.
15. Martins MJ, Negrao MR, Hipolito-Reis C, Azevedo I. Physiologic concentrations of bile salts inhibit rat hepatic alkaline phosphatase but not the intestinal isoenzyme. Clin Biochem 2000; 33: 611-617.
16. Van Belle H. Kinetics and inhibition of rat and avian alkaline phosphatases. Gen Pharmacol 1976; 7: 53-58.
17. Negrao MR, Mota A, Azevedo I, Martins MJ. Statins and tissue mineralization: putative involvement of alkaline phosphatase. Med Hypotheses 2006; 67: 524-528.
18. Keating E, Negrão MR, Martins MJ, Azevedo I. Human vascular smooth muscle cells ecto-ALP activity: modulation by steroids and phytochemicals. FASEB J 2004; 18: A285
19. Negrao MR, Keating E, Faria A, Azevedo I, Martins MJ. Acute effect of tea, wine, beer, and polyphenols on ectoalkaline phosphatase activity in human vascular smooth muscle cells. J Agric Food Chem 2006; 54: 4982-4988. (Abstract).
20. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976; 72: 248-254.
21. Goseki-Sone M, Oida S, Iimura T, Yamamoto A, Matsumoto HN, Omi N, et al. Expression of mRNA encoding intestinal type alkaline phosphatase in rat liver and its increase by fat-feeding. Liver 1996; 16: 358-364.
22. Xie Q, Alpers DH. The two isozymes of rat intestinal alkaline phosphatase are products of two distinct genes. Physiol Genomics 2000; 3: 1-8.
23. Muller E, Van Noorden S, Pearse AG. Ultrastructural localization of alkaline phosphatase in rat atrium. J Mol Cell Cardiol 1971; 3: 209-212.
24. Torun D, Sezer S, Baltali M, Adam FU, Erdem A, Ozdemir FN, et al. Association of cardiac valve calcification and inflammation in patients on hemodialysis. Ren Fail 2005; 27: 221-226.
25. Sanchez de Medina F, Martinez-Augustin O, Gonzalez R, Ballester I, Nieto A, Galvez J, et al. Induction of alkaline phosphatase in the inflamed intestine: a novel pharmacological target for inflammatory bowel disease. Biochem Pharmacol 2004; 68: 2317-2326.
26. Kapojos JJ, Poelstra K, Borghuis T, van den Berg A, Baelde HJ, Klok PA, et al. Induction of glomerular alkaline phosphatase after challenge with lipopolysaccharide. Int J Exp Pathol 2003; 84: 135-144.
27. Santos A, Alçada MN, Mota A, Martins MJ. Effect of beer, orange juice and soft drink on rat serum alkaline phosphatase. FASEB J 2005; 19: A1476 (Abstract).
28. Mody N, Parhami F, Sarafian TA, Demer LL. Oxidative stress modulates osteoblastic differentiation of vascular and bone cells. Free Radic Biol Med 2001; 31: 509-519.
29. Bravo L. Polyphenols: chemistry, dietary sources, metabolism, and nutritional significance. Nutr Rev 1998; 56: 317-333.
30. Kondo K. Beer and health: preventive effects of beer components on lifestyle-related diseases. Biofactors 2004; 22: 303-310.
31. Scalbert A, Manach C, Morand C, Remesy C, Jimenez L. Dietary polyphenols and the prevention of diseases. Crit Rev Food Sci Nutr 2005; 45: 287-306.
32. Sudano I, Binggeli C, Spieker L, Luscher TF, Ruschitzka F, Noll G, et al. Cardiovascular effects of coffee: is it a risk factor? Prog Cardiovasc Nurs 2005; 20: 65-69.
33. Teede HJ. Sex hormones and the cardiovascular system: effects on arterial function in women. Clin Exp Pharmacol Physiol 2007; 34: 672-676.
34. Maree AO, Fitzgerald DJ. Aspirin and coronary artery disease. Thromb Haemost 2004; 92: 1175-1181.
35. Khokher MA, Dandona P. The effect of indomethacin and aspirin on alkaline phosphatase secretion and [3H]thymidine incorporation by human osteoblasts. Br J Rheumatol 1988; 27: 291-294.
36. Horiuchi N, Maeda T. Statins and bone metabolism. Oral Dis 2006; 12: 85-101.
37. Ii M, Losordo DW. Statins and the endothelium. Vascul Pharmacol 2007; 46: 1-9.
38. Gilman AG, Rall TW, Nies AS, Taylor P. The pharmacological basis of therapeutics. 8th edn. New York: Pergamon Press; 1990.
39. Bonnet N, Gadois C, McCloskey E, Lemineur G, Lespessailles E, Courteix D, et al. Protective effect of beta blockers in postmenopausal women: influence on fractures, bone density, micro and macroarchitecture. Bone 2007; 40: 1209-1216.
40. Wu CH, Yang YC, Yao WJ, Lu FH, Wu JS, Chang CJ. Epidemiological evidence of increased bone mineral density in habitual tea drinkers. Arch Intern Med 2002; 162: 1001-1006.